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ZFX (human)

Overview ZFX Probable transcriptional activator. Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: C2H2-type zinc finger protein Cellular Component: nucleolus; nucleus Molecular Function: DNA binding; zinc ion binding; transcription coactivator activity Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent Reference #:  P17010 (UniProtKB) Alt. Names/Synonyms: X-linked zinc finger protein; ZFX; zinc finger protein, X-linked; Zinc finger X-chromosomal protein Gene Symbols: ZFX Molecular weight: 90,522 Da Basal Isoelectric point: 5.71  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below ZFX

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	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human ► Hide Isoforms
0	8		S274-p	GTVDIVEsEPENDHG
0	1		Y409	RRPDSRQYQTAIIIG
0	1		Y425-p	DGHPLTVyPCMICGK
0	1		K517-a	HKEKGANkMHKCKFC
0	2		T571-p	KKHMRIHtGEKPYQC

	ZFX iso3
S274	GTVDIVESEPENDHG
Y409-p	RRPDSRQyQTGEGAR
-	gap
-	gap
-	gap

	mouse
S269-p	GTVDIVEsEPENEHG
Y403	RRPDSRQYQTAIIIG
Y419	DGHPLTVYPCMICGK
K511-a	HKEKGANkMHKCKFC
T565	KKHMRIHTGEKPYEC

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