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Protein Page:
ZFX (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ZFX Probable transcriptional activator. Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding; transcription coactivator activity
Biological Process: embryonic development; fertilization; transcription, DNA-dependent; ovarian follicle development; regulation of transcription, DNA-dependent; death; multicellular organism growth; homeostasis of number of cells; spermatogenesis; oocyte development; post-embryonic development
Reference #:  P17010 (UniProtKB)
Alt. Names/Synonyms: X-linked zinc finger protein; ZFX; zinc finger protein, X-linked; Zinc finger X-chromosomal protein
Gene Symbols: ZFX
Molecular weight: 90,522 Da
Basal Isoelectric point: 5.71  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ZFX

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 2 T268-p GEDDLGGtVDIVEsE
0 13 S274-p GtVDIVEsEPENDHG
0 1 Y409 RRPDSRQYQTAIIIG
0 1 Y425-p DGHPLTVyPCMICGK
0 1 K517 HKEKGANKMHKCKFC
0 3 T571-p KKHMRIHtGEKPYQC
  ZFX iso3  
T272 GEDDLGGTVDIVESE
S278 GTVDIVESEPENDHG
Y413-p RRPDSRQyQTGEGAR
- gap
- gap
- gap
  mouse

 
T263 GEDDLGGTVDIVEsE
S269-p GTVDIVEsEPENEHG
Y403 RRPDSRQYQTAIIIG
Y419 DGHPLTVYPCMICGK
K511-ac HKEKGANkMHKCKFC
T565 KKHMRIHTGEKPYEC
  rat

 
T263 GEDDLGGTVDIVEsE
S269-p GTVDIVEsEPENEHG
Y403 RRPDSRQYQTESSTI
- gap
- gap
- gap
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