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Protein Page:
ZFX (human)

Overview
ZFX Probable transcriptional activator. Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding; transcription coactivator activity
Biological Process: embryonic development; fertilization; ovarian follicle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organism growth; death; homeostasis of number of cells; spermatogenesis; oocyte development; post-embryonic development
Reference #:  P17010 (UniProtKB)
Alt. Names/Synonyms: X-linked zinc finger protein; ZFX; zinc finger protein, X-linked; Zinc finger X-chromosomal protein
Gene Symbols: ZFX
Molecular weight: 90,522 Da
Basal Isoelectric point: 5.71  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ZFX

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 T268-p GEDDLGGtVDIVEsE
0 12 S274-p GtVDIVEsEPENDHG
0 1 Y409 RRPDSRQYQTAIIIG
0 2 T571-p KKHMRIHtGEKPYQC
  ZFX iso3  
T272 GEDDLGGTVDIVESE
S278 GTVDIVESEPENDHG
Y413-p RRPDSRQyQTGEGAR
- gap
  mouse

 
T263 GEDDLGGTVDIVEsE
S269-p GTVDIVEsEPENEHG
Y403 RRPDSRQYQTAIIIG
T565 KKHMRIHTGEKPYEC
  rat

 
T263 GEDDLGGTVDIVEsE
S269-p GTVDIVEsEPENEHG
Y403 RRPDSRQYQTESSTI
- gap
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