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Protein Page:
N-CoR1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
N-CoR1 is a protein that regulates the activity of some transcription factors, including nuclear receptors, by promoting histone deacetylation and chromatin condensation, thereby altering the accessibility of various genes to the transcriptional machinery. Is known to play a role genetic programming including that for myogenesis. Is a component of a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid and the retinoic acid receptors in the absence of ligand. Interacts with the catalytic domain of HDAC9. Increased expression correlates with the loss of vitamin D responsiveness in aggressive androgen-independent prostate cancer cells. Its gene tends to be overexpressed in multiple-myeloma cell lines. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Cellular Component: nucleoplasm; transcription factor complex; Sin3 complex; membrane; transcriptional repressor complex; spindle microtubule; cytoplasm; nuclear chromatin; histone deacetylase complex; nucleus
Molecular Function: retinoid X receptor binding; protein binding; histone deacetylase regulator activity; sequence-specific DNA binding; histone deacetylase binding; chromatin binding; thyroid hormone receptor binding; transcription factor activity; transcription corepressor activity; nuclear hormone receptor binding
Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; negative regulation of JNK cascade; Notch signaling pathway; transcription, DNA-dependent; regulation of multicellular organism growth; thalamus development; cellular lipid metabolic process; chromatin modification; spindle assembly; negative regulation of transcription from RNA polymerase II promoter; cholesterol homeostasis; positive regulation of histone deacetylation; transforming growth factor beta receptor signaling pathway; gene expression; circadian regulation of gene expression; negative regulation of phosphoinositide 3-kinase cascade
Reference #:  O75376 (UniProtKB)
Alt. Names/Synonyms: hCIT529I10; hN-CoR; KIAA1047; MGC104216; N-CoR; N-CoR1; NCOR1; nuclear receptor co-repressor 1; Nuclear receptor corepressor 1; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC1
Gene Symbols: NCOR1
Molecular weight: 270,210 Da
Basal Isoelectric point: 6.66  Predict pI for various phosphorylation states
CST Pathways:  ErbB/HER Signaling  |  Protein Acetylation
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

N-CoR1

Protein Structure Not Found.


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Sites Implicated In
transcription, induced: S1450‑p
transcription, inhibited: S70‑p
intracellular localization: S70‑p
protein conformation: S1450‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 Y20-p FSTEQSRyPPHSVQY
0 1 S51 RSSHLEVSQASQLLQ
1 83 S70-p QQLRRRPsLLsEFHP
0 4 S73-p RRRPsLLsEFHPGSD
0 1 T87-p DRPQERRtsyEPFHP
1 6 S88-p RPQERRtsyEPFHPG
0 5 Y89-p PQERRtsyEPFHPGP
0 20 S97-p EPFHPGPsPVDHDSL
0 1 S106-p VDHDSLEsKRPRLEQ
1 0 K152 KDPAFGGKHEAPssP
0 4 S157-p GGKHEAPssPIsGQP
0 9 S158-p GKHEAPssPIsGQPC
0 1 S161-p EAPssPIsGQPCGDD
0 12 S172-p CGDDQNAsPsKLSKE
0 1 S174-p DDQNAsPsKLSKEEL
0 19 S224-p PEPEKPVsPPPVEQK
0 1 Y275-p QPSDTKVyHENIKTN
0 1 K294-ub KKLILFFkRRNHARK
0 1 D385-ca HEISEIIdGLSEQEN
0 1 K395 SEQENNEKQMRQLsV
0 1 S401-p EKQMRQLsVIPPMMF
0 1 Y477-p SVPDCVLyyYLTKKN
0 1 Y478-p VPDCVLyyYLTKKNE
0 1 S509-p NQQIARPsQEEKVEE
0 1 K533-ac EKKEEEKkDEEEKDE
0 1 D555-ca TKEKDKIdGTAEETE
0 4 T568-p TEEREQAtPRGRKTA
0 3 T586-p GRRKGRItRsMtNEA
0 12 S588-p RKGRItRsMtNEAAA
0 15 T590-p GRItRsMtNEAAAAS
0 3 S764 TETAPSTSPSLAVPS
0 1 S766 TAPSTSPSLAVPSTK
0 1 L767 APSTSPSLAVPSTKP
0 1 K842-ac KVEGDNTkERDLDRA
0 1 S918 TGSILVSSPLKPNPL
0 1 S989-p QIDLECRssTsPCGT
0 1 S990-p IDLECRssTsPCGTs
0 1 S992-p LECRssTsPCGTsKs
0 1 S997-p sTsPCGTsKsPNREW
0 15 S999-p sPCGTsKsPNREWEV
0 1 - gap
0 2 - gap
0 4 - gap
0 1 T1026 PEGVRLPTTRPTRPP
0 1 T1030 RLPTTRPTRPPPPLI
1 0 K1106 SATLPYIKQEEFsPR
0 15 S1111-p YIKQEEFsPRSQNsQ
0 1 S1117-p FsPRSQNsQPEGLLV
0 1 T1145-p AIQEGSItRGtPTsK
0 1 T1148-p EGSItRGtPTsKISV
0 1 S1151-p ItRGtPTsKISVESI
0 1 S1164-p SIPSLRGsITQGTPA
0 4 S1195-p SRMPIEDssPEKGRE
0 3 S1196-p RMPIEDssPEKGREE
0 1 S1206-p KGREEAAsKGHVIyE
0 19 Y1212-p AsKGHVIyEGKSGHI
0 1 S1221-p GKSGHILsyDNIKNA
0 1 Y1222-p KSGHILsyDNIKNAR
0 1 S1242-p PRTAHEIsLKRsyEs
0 1 S1246-p HEIsLKRsyEsVEGN
0 1 Y1247-p EIsLKRsyEsVEGNI
0 11 S1249-p sLKRsyEsVEGNIKQ
0 3 S1263-p QGMSMREsPVSAPLE
0 2 S1281-p CRALPRGsPHsDLKE
0 1 S1284-p LPRGsPHsDLKERTV
0 1 S1293-p LKERTVLsGSIMQGt
0 13 T1300-p sGSIMQGtPRATTES
1 0 K1319 LKYPKQIKREsPPIR
0 10 S1322-p PKQIKREsPPIRAFE
0 1 T1333-p RAFEGAItKGkPYDG
0 2 K1336-ac EGAItKGkPYDGITT
0 5 T1367-p LTQESRKtPEVVQST
0 1 S1405-p AIKHNVKsLItGPsk
0 1 T1408-p HNVKsLItGPskLsR
0 1 S1411-p KsLItGPskLsRGMP
0 1 K1412-ac sLItGPskLsRGMPP
0 1 K1412-ub sLItGPskLsRGMPP
0 1 S1414-p ItGPskLsRGMPPLE
0 2 Y1435-p KVVERGKyEDVKAGE
0 1 T1443-p EDVKAGEtVRSRHts
0 5 T1449-p EtVRSRHtsVVsSGP
1 52 S1450-p tVRSRHtsVVsSGPs
0 1 S1453-p SRHtsVVsSGPsVLR
0 1 S1457-p sVVsSGPsVLRSTLH
0 57 S1472-p EAPKAQLsPGIyDDt
0 19 Y1476-p AQLsPGIyDDtSARR
0 1 T1479-p sPGIyDDtSARRtPV
0 23 T1484-p DDtSARRtPVsyQNT
0 4 S1487-gl SARRtPVsyQNTMsR
0 2 Y1488-p ARRtPVsyQNTMsRG
0 1 S1493-p VsyQNTMsRGsPMMN
0 1 S1496-p QNTMsRGsPMMNRTS
0 1 K1518 KSTNHERKSTLtPTQ
0 1 T1520 TNHERKSTLtPTQRE
0 4 T1522-p HERKSTLtPTQREsI
0 1 S1528-p LtPTQREsIPAKsPV
0 10 S1533-p REsIPAKsPVPGVDP
0 1 S1543-p PGVDPVVsHsPFDPH
0 5 S1545-p VDPVVsHsPFDPHHR
0 4 Y1560-p GSTAGEVyRSHLPTH
0 3 S1592-p YLFQRQLsPtPGyPS
0 1 T1594-p FQRQLsPtPGyPSQY
0 2 Y1597-p QLsPtPGyPSQYQLY
0 1 S1599 sPtPGyPSQYQLYAM
0 1 T1612 AMENTRQTILNDYIT
0 1 Y1617 RQTILNDYITSQQMQ
0 1 R1628-m2 QQMQVNLrPDVARGL
0 6 T1670-p LVPHPGGtstPPMDR
0 5 S1671-p VPHPGGtstPPMDRI
0 2 T1672-p PHPGGtstPPMDRIT
0 1 S1742-p DLYLRPGsEQPGRPG
0 4 S1750-p EQPGRPGsHGyVRsP
0 4 Y1753-p GRPGsHGyVRsPsPS
0 8 S1756-p GsHGyVRsPsPSVRT
0 11 S1758-p HGyVRsPsPSVRTQE
0 1 S1760 yVRsPsPSVRTQEtM
0 1 T1766-p PSVRTQEtMLQQRPS
0 1 T1785-p TNGTSVItPLDPTAQ
0 2 S1806-p PAGGPSIsQGLPASR
0 1 Y1814 QGLPASRYNTAADAL
0 1 D1826-ca DALAALVdAAASAPQ
0 1 T1839 PQMDVSKTKESKHEA
0 1 S1842 DVSKTKESKHEAARL
0 2 T1883 RSVQCLYTSSAFPSG
0 1 S1884 SVQCLYTSSAFPSGK
0 1 S1955-p RERGSQSsDsSssLS
0 1 S1957-p RGSQSsDsSssLSsH
0 1 S1959-p SQSsDsSssLSsHRY
0 1 S1960-p QSsDsSssLSsHRYE
0 1 S1963-p DsSssLSsHRYETPS
0 16 S1977-p SDAIEVIsPAssPAP
0 3 S1980-p IEVIsPAssPAPPQE
0 11 S1981-p EVIsPAssPAPPQEK
0 7 T2050-p PRTHRLItLADHICQ
0 3 S2084-p PTSTFQNsPsALVst
0 1 S2086-p STFQNsPsALVstPV
0 1 S2090-p NsPsALVstPVRTKT
0 4 T2091-p sPsALVstPVRTKTS
0 4 S2102-p TKTSNRYsPEsQAQS
0 1 S2105-p SNRYsPEsQAQSVHH
0 21 S2120-p QRPGSRVsPENLVDK
0 1 S2128 PENLVDKSRGSRPGK
0 1 S2131 LVDKSRGSRPGKsPE
0 5 S2136-p RGSRPGKsPERSHVS
0 2 Y2147-p SHVSSEPyEPIsPPQ
0 21 S2151-p SEPyEPIsPPQVPVV
0 5 S2169-p QDSLLLLsQRGAEPA
0 27 S2184-p EQRNDARsPGsISyL
0 6 S2187-p NDARsPGsISyLPSF
0 1 S2189 ARsPGsISyLPSFFT
0 1 Y2190-p RsPGsISyLPSFFTK
0 1 S2193 GsISyLPSFFTKLEN
0 2 T2201-p FFTKLENtsPMVKSK
0 2 S2202-p FTKLENtsPMVKSKK
0 3 S2218-p EIFRKLNssGGGDsD
0 4 S2219-p IFRKLNssGGGDsDM
0 3 S2224-p NssGGGDsDMAAAQP
0 1 G2251 SGSVSSRGHsFADPA
0 4 S2253-p SVSSRGHsFADPAsN
0 2 S2259-p HsFADPAsNLGLEDI
0 1 S2315-p RREEGDPsPHSGGVC
1 0 S2332 KLISKSNSRKsKsPI
1 1 S2335-p SKSNSRKsKsPIPGQ
0 6 S2337-p SNSRKsKsPIPGQGY
0 1 T2347-p PGQGYLGtERPSsVs
0 3 S2352-p LGtERPSsVssVHsE
0 2 S2354-p tERPSsVssVHsEGD
0 3 S2355-p ERPSsVssVHsEGDY
0 3 S2358-p SsVssVHsEGDYHRQ
0 35 S2394-p PLTMRMLsstPPtPI
0 3 S2395-p LTMRMLsstPPtPIA
0 10 T2396-p TMRMLsstPPtPIAC
0 16 T2399-p MLsstPPtPIACAPS
0 1 Y2432-p APLLSAQyEtLsDsD
0 2 T2434-p LLSAQyEtLsDsDD_
1 18 S2436-p SAQyEtLsDsDD___
0 18 S2438-p QyEtLsDsDD_____
  mouse

► Hide Isoforms
 
Y20 FSTEQSRYPSHSVQY
S51-gl RSSHLEVsQASQLLQ
S70-p QQLRRRPsLLsEFHP
S73-p RRRPsLLsEFHPGSD
S87 DRPQERRSGYEQFHP
G88 RPQERRSGYEQFHPG
Y89 PQERRSGYEQFHPGP
S97 EQFHPGPSPVDHDSL
S106 VDHDSLESKRPRLEQ
K152-sm KDPAFGVkHEAPssP
S157-p GVkHEAPssPLSGQP
S158-p VkHEAPssPLSGQPC
S161 EAPssPLSGQPCGDD
S172-p CGDDQNAsPSKLSKE
S174 DDQNAsPSKLSKEEL
S224-p PEPEKPVsPPPVEQK
Y275 QPSDTKVYHENIKTN
K294 KKLILFFKRRNHARK
D385 HEISEIIDGLSEQEN
K395-ub SEQENNEkQMRQLSV
S401 EkQMRQLSVIPPMMF
Y477 SVPDCVLYYYLTKKN
Y478 VPDCVLYYYLTKKNE
S509 NQQIARPSQEEKVEE
K533 EKKEEEKKDDEEKDD
E555 TKEKDRTEATAEEPE
T568 PEEREQVTPRGRKTA
T586 GRGKGRVTRSMTSEA
S588 GKGRVTRSMTSEAAA
T590 GRVTRSMTSEAAAAN
S779-p TDPAPCAsPssAVPT
S781-p PAPCAsPssAVPTTK
S782-p APCAsPssAVPTTKP
K856 SKGEGDAKERDLEST
S930 PGSILISSPIKPNLL
S1001-p QVDLECRssTsPCST
S1002-p VDLECRssTsPCSTs
S1004-p LECRssTsPCSTsKs
S1009-p sTsPCSTsKsPNREW
S1011-p sPCSTsKsPNREWEV
- gap
- gap
- gap
T1038-p PEGVRLPtTRPtRPP
T1042-p RLPtTRPtRPPPPLI
K1117-sm AAPLTYIkQEEFsPR
S1122-p YIkQEEFsPRSQNSQ
S1128 FsPRSQNSQPEGLLV
T1156 AVQEGSITRGTPASK
T1159 EGSITRGTPASKISV
S1162 ITRGTPASKISVETI
S1175 TISSLRGSITQGTPA
S1206-p SRMPIEEssPEKVRE
S1207-p RMPIEEssPEKVREE
S1217 KVREEAASKGHVIYE
Y1223 ASKGHVIYEGKSGHI
S1232 GKSGHILSYDNIKNA
Y1233 KSGHILSYDNIKNAR
S1253 PRTAHEMSLKRSYEA
S1257 HEMSLKRSYEAVEGS
Y1258 EMSLKRSYEAVEGSI
A1260 SLKRSYEAVEGSIKQ
S1274-p QGMSMREsPVSAPLE
S1292 CRALPRGSPHSDLKE
S1295 LPRGSPHSDLKERTV
S1304 LKERTVLSGSIMQGT
T1311 SGSIMQGTPRATAES
K1330-sm LKYPKQIkREsPPIR
S1333-p PKQIkREsPPIRAFE
T1344 RAFEGAITKGKPYDG
K1347 EGAITKGKPYDGITT
T1378-p LTQESRKtPEVVQST
S1416 AIKHNVKSLITGPSK
T1419 HNVKSLITGPSKLPR
S1422 KSLITGPSKLPRGML
K1423 SLITGPSKLPRGMLE
K1423 SLITGPSKLPRGMLE
P1425 ITGPSKLPRGMLEIV
Y1444 KVVERGKYEDVKAGE
P1452 EDVKAGEPVRARHTs
T1458 EPVRARHTsVVSSGP
S1459-p PVRARHTsVVSSGPS
S1462 ARHTsVVSSGPSVLR
S1466 sVVSSGPSVLRSTLH
S1481-p EAPKAQLsPGLYDDS
Y1485 AQLsPGLYDDSSARR
S1488 sPGLYDDSSARRtPV
T1493-p DDSSARRtPVsYQNT
S1496-gl SARRtPVsYQNTISR
Y1497 ARRtPVsYQNTISRG
S1502 VsYQNTISRGSPMMN
S1505 QNTISRGSPMMNRTS
K1525-ub KSASHERkStLtPTQ
T1527-p ASHERkStLtPTQRE
T1529-p HERkStLtPTQRESI
S1535 LtPTQRESIPAKsPV
S1540-p RESIPAKsPVPGVDP
S1550 PGVDPIVSHSPFDPH
S1552 VDPIVSHSPFDPHHR
Y1567 SSAAGEVYRSHLPTH
S1598-p YLLQRQLsPtPGyPs
T1600-p LQRQLsPtPGyPsQY
Y1603-p QLsPtPGyPsQYQLY
S1605-p sPtPGyPsQYQLYAM
T1618 AMENTRQTILNDYIT
Y1623 RQTILNDYITSQQMQ
R1634 QQMQVNLRPDVTRGL
T1676 LVPHAGGTSTPPMDR
S1677 VPHAGGTSTPPMDRI
T1678 PHAGGTSTPPMDRIT
S1758-p DLYLRPGsEQPGRPG
S1766-p EQPGRPGsHGyVRsP
Y1769-p GRPGsHGyVRsPsPs
S1772-p GsHGyVRsPsPsVRT
S1774-p HGyVRsPsPsVRTQE
S1776-p yVRsPsPsVRTQETI
T1782 PsVRTQETILQQRPS
T1801 TNGTSVITPLDPTAQ
S1822 PSGGPSISQGLPASR
Y1830-p QGLPASRyNTAADAL
D1842 DALAALVDAAASAPQ
T1855-p PQMDVSKtKEsKHEA
S1858-p DVSKtKEsKHEAARL
T1899-gl RSVQCVCtsSALPSG
S1900-gl SVQCVCtsSALPSGK
S1971 RERGSQSSDSSSSLS
S1973 RGSQSSDSSSSLSSH
S1975 SQSSDSSSSLSSHRY
S1976 QSSDSSSSLSSHRYE
S1979 DSSSSLSSHRYETAS
S1993-p SDAIEVIsPAssPAP
S1996-p IEVIsPAssPAPPQE
S1997-p EVIsPAssPAPPQEK
T2068 PRTHRLITLADHICQ
S2098-p STSTFQTsPSALSST
S2100 STFQTsPSALSSTPV
S2104 TsPSALSSTPVRTKT
T2105 sPSALSSTPVRTKTS
S2116-p TKTSSRYsPESQSQT
S2119 SSRYsPESQSQTVLH
S2134-p PRPGPRVsPENLVDK
S2142-p PENLVDKsRGsRPGK
S2145-p LVDKsRGsRPGKsPE
S2150-p RGsRPGKsPERSHIP
Y2161 SHIPSEPYEPIsPPQ
S2165-p SEPYEPIsPPQGPAV
S2183 QDSMLLLSQRGVDPA
S2198-p EQRSDSRsPGsIsYL
S2201-p SDSRsPGsIsYLPSF
S2203-p SRsPGsIsYLPSFFT
Y2204 RsPGsIsYLPSFFTK
S2207 GsIsYLPSFFTKLES
T2215 FFTKLESTSPMVKSK
S2216 FTKLESTSPMVKSKK
S2232-p EIFRKLNssGGGDsD
S2233-p IFRKLNssGGGDsDM
S2238-p NssGGGDsDMAAAQP
S2265-p SGAVSSRsHsFADPA
S2267-p AVSSRsHsFADPAsN
S2273-p HsFADPAsNLGLEDI
S2329-p RRDEGEPsPHAGVCK
S2345-p KLINKSNsRKsKsPI
S2348-p NKSNsRKsKsPIPGQ
S2350-p SNsRKsKsPIPGQSY
T2360 PGQSYLGTERPSsVS
S2365-p LGTERPSsVSSVHsE
S2367 TERPSsVSSVHsEGD
S2368 ERPSsVSSVHsEGDY
S2371-p SsVSSVHsEGDYHRQ
S2407-p PLTIRMLsStPPTQI
S2408 LTIRMLsStPPTQIA
T2409-p TIRMLsStPPTQIAC
T2412 MLsStPPTQIACAPS
Y2445 APLLSAQYETLsDsD
T2447 LLSAQYETLsDsDD_
S2449-p SAQYETLsDsDD___
S2451-p QYETLsDsDD_____
  N-CoR1 iso4  
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S2 ______LSVIPPMMF
Y78 SVPDCVLYYYLTKKN
Y79 VPDCVLYYYLTKKNE
S110 NQQIARPSQEEKVEE
K134 EKKEEEKKDDEEKDD
E156 TKEKDRTEATAEEPE
T169 PEEREQVTPRGRKTA
T187 GRRKGRVTRSMTSEA
S189 RKGRVTRSMTSEAAA
T191 GRVTRSMTSEAAAAN
S370 TDPAPCASPSSAVPT
S372 PAPCASPSSAVPTTK
S373 APCASPSSAVPTTKP
K447 SKGEGDAKERDLEST
S521-p PGSILISsPIKPNPL
S592 QVDLECRSSTSPCST
S593 VDLECRSSTSPCSTS
S595 LECRSSTSPCSTSKs
S600 STSPCSTSKsPNREW
S602-p SPCSTSKsPNREWEG
S637-p MHSTAARsAsPCRLs
S639-p STAARsAsPCRLsPR
S644-p sAsPCRLsPREVSKA
T687 PEGVRLPTTRPTRPP
T691 RLPTTRPTRPPPPLI
K766 AAPLTYIKQEEFSPR
S771 YIKQEEFSPRSQNSQ
S777 FSPRSQNSQPEGLLV
T805 AVQEGSITRGTPASK
T808 EGSITRGTPASKISV
S811 ITRGTPASKISVETI
S824 TISSLRGSITQGTPA
S855 SRMPIEESSPEKVRE
S856 RMPIEESSPEKVREE
S866 KVREEAASKGHVIYE
Y872 ASKGHVIYEGKSGHI
S881 GKSGHILSYDNIKNA
Y882 KSGHILSYDNIKNAR
S902 PRTAHEMSLKRSYEA
S906 HEMSLKRSYEAVEGS
Y907 EMSLKRSYEAVEGSI
A909 SLKRSYEAVEGSIKQ
S923 QGMSMRESPVSAPLE
S941 CRALPRGSPHSDLKE
S944 LPRGSPHSDLKERTV
S953 LKERTVLSGSIMQGT
T960 SGSIMQGTPRATAES
K979 LKYPKQIKRESPPIR
S982 PKQIKRESPPIRAFE
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  rat

 
Y20 FSTEQSRYPSQSVQY
S51 RSSHIEVSQASQLLQ
S71-p QQLRRRPsLLSEFHP
S74 RRRPsLLSEFHPGSD
T88 DRPQERRTGYEQFHS
G89 RPQERRTGYEQFHSG
Y90 PQERRTGYEQFHSGP
S98 EQFHSGPSPVDHDSL
S107 VDHDSLESKRPRLEP
K153 KDSAFGGKHEAPSSP
S158 GGKHEAPSSPLAGQP
S159 GKHEAPSSPLAGQPC
A162 EAPSSPLAGQPCGDD
S173 CGDDQNASPSKLSKE
S175 DDQNASPSKLSKEEL
S225-p PEPEKPVsPPPVEQK
Y276 QPSDTKVYHENIKTG
K304 KKLILFFKRRNHARK
D395 HEISEIIDGLSEQEN
K405 SEQENNEKQMRQLSV
S411 EKQMRQLSVIPPMMF
Y487 SVPDCVLYYYLTKKN
Y488 VPDCVLYYYLTKKNE
S519 NQQIARPSQEEKVEE
K543 EKKEEEKKDDEEKDE
E565 TKEKDRTEATAEETE
T578 TEEREQVTPRGRKTA
T596 GRRKGRITRSMTSEA
S598 RKGRITRSMTSEAAA
T600 GRITRSMTSEAAAAS
S779 TDPAPCASPSSAVPT
S781 PAPCASPSSAVPTTK
S782 APCASPSSAVPTTKP
K856 SKGEGDAKDRDLESA
S930 PGSILISSPIKPNPL
S1001 QIDLECRSSTSPCGT
S1002 IDLECRSSTSPCGTS
S1004 LECRSSTSPCGTSKS
S1009 STSPCGTSKSPNREW
S1011 SPCGTSKSPNREWEG
- gap
- gap
- gap
T1096 PEGVRLPTTRPTRPP
T1100 RLPTTRPTRPPPPLI
K1175 SAPLTYIKQEEFSPR
S1180 YIKQEEFSPRSQNSQ
S1186 FSPRSQNSQPEGLLV
T1214 AVQEGSITRGTPASK
T1217 EGSITRGTPASKISV
S1220 ITRGTPASKISVESI
S1233 SISSLRGSITQGTPA
S1264 SRMPIEESSPEKVRE
S1265 RMPIEESSPEKVREE
S1275 KVREEAASKGHVIYE
Y1281 ASKGHVIYEGKSGHI
S1290 GKSGHILSYDNIKNA
Y1291 KSGHILSYDNIKNAR
S1311 PRTAHEMSLKRSYES
S1315 HEMSLKRSYESVEGN
Y1316 EMSLKRSYESVEGNV
S1318 SLKRSYESVEGNVKQ
S1332 QGMSMRESPVSAAPL
S1351 CRALPRGSPHSDLKE
S1354 LPRGSPHSDLKERTV
S1363 LKERTVLSGSIMQGT
T1370 SGSIMQGTPRATAES
K1389 LKYPKQIKREsPPSR
S1392-p PKQIKREsPPSRAFE
T1403 RAFEGAITKGKPYDG
K1406 EGAITKGKPYDGITT
T1437 LTQESRKTPEVVQST
S1475 AIKHNVKSLITGPSK
T1478 HNVKSLITGPSKLPR
S1481 KSLITGPSKLPRGML
K1482 SLITGPSKLPRGMLE
K1482 SLITGPSKLPRGMLE
P1484 ITGPSKLPRGMLEIV
Y1503 KVVERGKYEDVKAGE
P1511 EDVKAGEPVRPRHTS
T1517 EPVRPRHTSVVSSGP
S1518 PVRPRHTSVVSSGPS
S1521 PRHTSVVSSGPSVLR
S1525 SVVSSGPSVLRSTLH
S1540-p EAPKAQLsPGIYDDS
Y1544 AQLsPGIYDDSSARR
S1547 sPGIYDDSSARRTPV
T1552 DDSSARRTPVSYQNT
S1555 SARRTPVSYQNTISR
Y1556 ARRTPVSYQNTISRG
S1561 VSYQNTISRGSPMMN
S1564 QNTISRGSPMMNRTS
K1584 KTTSHERKSALTPTQ
A1586 TSHERKSALTPTQRE
T1588 HERKSALTPTQRESV
S1594 LTPTQRESVPAKSPV
S1599 RESVPAKSPVPAVDS
S1609 PAVDSVVSHSPFDPH
S1611 VDSVVSHSPFDPHHR
Y1626 STTAGEVYRSHLPTH
S1658 YLFQRQLSPTPGYPS
T1660 FQRQLSPTPGYPSQY
Y1663 QLSPTPGYPSQYQLY
S1665 SPTPGYPSQYQLYAM
T1678-p AMENTRQtILNDyIT
Y1683-p RQtILNDyITSQQMQ
R1694 QQMQVNLRPDVARGL
T1736 LVPHAGGTSTPPMDR
S1737 VPHAGGTSTPPMDRI
T1738 PHAGGTSTPPMDRIT
S1830 DLYLRPGSEQPGRPG
S1838 EQPGRPGSHGYVRSP
Y1841 GRPGSHGYVRSPSPS
S1844 GSHGYVRSPSPSVRT
S1846 HGYVRSPSPSVRTQE
S1848 YVRSPSPSVRTQETM
T1854 PSVRTQETMLQQRPS
T1873 TNGTSVITPLDPTAQ
S1894 PSGGPSISQGLPASR
Y1902 QGLPASRYNTAADAL
D1914 DALAALVDAAASAPQ
T1927 PQMDVSKTKESKHEA
S1930 DVSKTKESKHEAARL
T1971 RSVQCVCTSSALPSG
S1972 SVQCVCTSSALPSGK
S2043 RERGSQSSDSSSSLS
S2045 RGSQSSDSSSSLSSH
S2047 SQSSDSSSSLSSHRY
S2048 QSSDSSSSLSSHRYE
S2051 DSSSSLSSHRYEAPS
S2065 SDAIEVISPASSPAP
S2068 IEVISPASSPAPPQE
S2069 EVISPASSPAPPQEK
T2140 PRTHRLITLADHICQ
S2170-p STSTFQTsPSALSST
S2172 STFQTsPSALSSTPV
S2176 TsPSALSSTPVRTKP
T2177 sPSALSSTPVRTKPS
S2188-p TKPSSRYsPEsQSQT
S2191-p SSRYsPEsQSQTVLH
S2206-p PRPGPRVsPENLVDK
S2214 PENLVDKSRGSRPGK
S2217 LVDKSRGSRPGKSPE
S2222 RGSRPGKSPERSHIP
Y2233 SHIPSEPYEPIsPPQ
S2237-p SEPYEPIsPPQGPAV
S2255 QDSMLLLSQRGMDPA
S2270-p EQRSDSRsPGsIsyL
S2273-p SDSRsPGsIsyLPsF
S2275-p SRsPGsIsyLPsFFT
Y2276-p RsPGsIsyLPsFFTK
S2279-p GsIsyLPsFFTKLES
T2287-p FFTKLEStSPMVKSK
S2288 FTKLEStSPMVKSKK
S2304 EIFRKLNSSGGGDSD
S2305 IFRKLNSSGGGDSDM
S2310 NSSGGGDSDMAAAQP
S2337 SGAVSSRSHSFADPA
S2339 AVSSRSHSFADPASN
S2345 HSFADPASNLGLEDI
S2401 RRDEGDPSPHSGVCK
S2417 KLINKSNSRKSKSPI
S2420 NKSNSRKSKSPIPGQ
S2422 SNSRKSKSPIPGQNY
T2432 PGQNYLGTERPSSVS
S2437 LGTERPSSVSSVHSE
S2439 TERPSSVSSVHSEGD
S2440 ERPSSVSSVHSEGDY
S2443 SSVSSVHSEGDYHRQ
S2479 PLTIRMLSSTPPTPI
S2480 LTIRMLSSTPPTPIA
T2481 TIRMLSSTPPTPIAC
T2484 MLSSTPPTPIACAPS
Y2517 APLLSAQYETLSDSD
T2519 LLSAQYETLSDSDD_
S2521 SAQYETLSDSDD___
S2523 QYETLSDSDD_____
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