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Protein Page:
ACC1 (mouse)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Phosphorylation by AMPK or PKA inhibits the enzymatic activity of ACC. ACC-alpha is the predominant isoform in liver, adipocyte and mammary gland. ACC-beta is the major isoform in skeletal muscle and heart. Phosphorylation regulates its activity. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid biosynthesis; Ligase; EC 6.4.1.2; Carbohydrate Metabolism - pyruvate; EC 6.3.4.14
Cellular Component: mitochondrion; cytoplasm; cytosol
Molecular Function: protein binding; acetyl-CoA carboxylase activity; metal ion binding; nucleotide binding; biotin carboxylase activity; catalytic activity; kinase binding; biotin binding; ATP binding; ligase activity
Biological Process: acetyl-CoA metabolic process; metabolic process; multicellular organismal protein metabolic process; tissue homeostasis; lipid homeostasis; lipid metabolic process; fatty acid metabolic process; response to organic cyclic substance; fatty acid biosynthetic process; protein homotetramerization
Reference #:  Q5SWU9 (UniProtKB)
Alt. Names/Synonyms: A530025K05Rik; Acac; Acaca; ACC-alpha; Acc1; Acetyl-CoA carboxylase 1; Acetyl-CoA carboxylase 265; acetyl-Coenzyme A carboxylase alpha; Biotin carboxylase; Gm738; OTTMUSP00000000931
Gene Symbols: Acaca
Molecular weight: 265,257 Da
Basal Isoelectric point: 5.97  Predict pI for various phosphorylation states
CST Pathways:  AMPK Signaling  |  Warburg Effect
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ACC1

Protein Structure Not Found.


STRING  |  Reactome  |  BioGPS  |  Scansite  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UCSD-Nature  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

► Hide Isoforms
 
0 4 - gap
0 8 - gap
0 1 - gap
0 1 - gap
0 6 S5-p ___MDEPsPLAktLE
0 1 K9-ub DEPsPLAktLELNQH
0 1 T10-p EPsPLAktLELNQHs
0 1 S17-p tLELNQHsRFIIGsV
1 18 S23-p HsRFIIGsVsEDNsE
1 19 S25-p RFIIGsVsEDNsEDE
1 48 S29-p GsVsEDNsEDEIsNL
0 1 S34-p DNsEDEIsNLVKLDL
0 10 S47-p DLEEKEGsLsPAsVs
0 9 S49-p EEKEGsLsPAsVsSD
0 2 S52-p EGsLsPAsVsSDtLs
0 2 S54-p sLsPAsVsSDtLsDL
0 2 S55 LsPAsVsSDtLsDLG
0 1 T57-p PAsVsSDtLsDLGIS
0 2 S59-p sVsSDtLsDLGISGL
0 1 S76 GLAFHMRSsMsGLHL
6 0 S77-p LAFHMRSsMsGLHLV
99 48 S79-p FHMRSsMsGLHLVKQ
0 4 K85 MsGLHLVKQGRDRKK
0 1 S95-p RDRKKIDsQRDFTVA
0 1 T157-p IRFVVMVtPEDLKAN
0 1 S233 IAFMGPPSQAMWALG
0 2 K275-ub WQENDFSkRILNVPQ
0 1 Y285 LNVPQDLYEkGYVKD
0 3 K287-ub VPQDLYEkGYVKDVD
0 2 Y289 QDLYEkGYVKDVDDG
0 1 K310 VGYPVMIKASEGGGG
0 1 S343 VQAEVPGSPIFVMRL
0 1 Y416 KLAKMVGYVSAGTVE
0 1 Y433 YSQDGSFYFLELNPR
0 1 A487 GVSPWGDAPIDFENS
0 1 K519-ac ENPDEGFkPSSGTVQ
0 2 K519-ub ENPDEGFkPSSGTVQ
0 1 K578 SNMVVALKELSIRGD
0 3 T609-p FQLNRIDtGWLDRLI
0 1 Y675 TVDVELIYEGIKYVL
0 2 Y733-p MKEEVDRyRITIGNK
0 1 S755 NDPSVMRSPSAGKLI
0 1 Y800 VESGCIHYVKRPGAA
0 2 K824-ub MQLDNPSkVQQAELH
0 1 S834 QAELHTGSLPQIQST
0 1 S840 GSLPQIQSTALRGEK
0 1 Y854 KLHRVFHYVLDNLVN
0 1 Y866 LVNVMNGYCLPDPFF
0 1 S892 MKTLRDPSLPLLELQ
0 1 S906 QDIMTSVSGRIPLNV
0 1 K915-ub RIPLNVEkSIKKEMA
0 1 S976 QLVQRYRSGIRGHMK
0 2 T1041 TKKNLLVTMLIDQLC
0 1 T1072 LTQLSKTTNAKVALR
0 1 S1101-p LRHNQVEsIFLsAID
0 1 S1105-p QVEsIFLsAIDMyGH
0 1 Y1110-p FLsAIDMyGHQFCIE
0 5 T1195-p PNRGNIPtLNRMsFA
3 3 S1200-p IPtLNRMsFAsNLNH
0 2 S1203-p LNRMsFAsNLNHyGM
0 2 Y1208-p FAsNLNHyGMtHVAs
0 2 T1211-p NLNHyGMtHVAsVsD
3 4 S1215-p yGMtHVAsVsDVLLD
0 5 S1217-p MtHVAsVsDVLLDNA
0 3 T1226-p VLLDNAFtPPCQRMG
0 1 C1256 DEIMGCFCDsPPQsP
0 12 S1258-p IMGCFCDsPPQsPtF
2 9 S1262-p FCDsPPQsPtFPESG
0 6 T1264-p DsPPQsPtFPESGHT
0 1 S1272 FPESGHTSLYDEDKV
0 2 K1315-ub REFTQQNkATLVEHG
0 2 K1333 LTFLVAQKDFRkQVN
0 1 K1337-ub VAQKDFRkQVNCEVD
0 3 C1341 DFRkQVNCEVDQRFH
0 23 Y1369-p KFEEDRIyRHLEPAL
0 1 K1434 RHSDLVTKEASFEYL
0 1 Y1498 VRSMVMRYGSRLWKL
0 2 K1579 INTPYVTKDLLQSKR
0 1 K1662-ub EIGMVAWkMSLkSPE
0 1 K1666-ub VAWkMSLkSPEYPDG
0 1 S1719 RIYVAANSGARIGLA
0 1 K1748-ub EDPYKGYkYLYLTPQ
0 3 K1758-ac YLTPQDYkRVSALNS
0 2 K1758-ub YLTPQDYkRVSALNS
0 1 K1758-sc YLTPQDYkRVSALNS
0 1 K1780-ub DEGESRYkITDIIGk
0 1 K1787 kITDIIGKEEGLGAE
0 2 K1787-ub kITDIIGkEEGLGAE
0 2 S1843 RTIQVENSHLILTGA
0 1 K1855 TGAGALNKVLGREVY
0 1 K1855 TGAGALNKVLGREVY
0 1 S1907 YMPKSVHSSVPLLNS
0 1 K1915 SVPLLNSKDPIDRII
0 2 K1928-ub IIEFVPTkAPYDPRW
0 1 S1995-p ETRTVELsIPADPAN
0 1 S2005-p ADPANLDsEAKIIQQ
0 1 K2030 FKTYQAIKDFNREGL
0 1 K2030-ub FKTYQAIkDFNREGL
0 1 R2046 LMVFANWRGFSGGMk
0 1 K2053-ub RGFSGGMkDMYDQVL
0 1 T2098 SWVVIDPTINPRHME
0 1 Y2107 NPRHMEMYADRESRG
0 2 K2126-ac PEGTVEIkFRKKDLV
0 1 K2126-ub PEGTVEIkFRKKDLV
0 4 Y2143 MRRVDPVYIRLAERL
0 3 T2152-p RLAERLGtPELsPtE
0 1 S2156-p RLGtPELsPtERKEL
0 1 T2158-p GtPELsPtERKELES
0 1 K2208 INDILDWKTSRTFFY
0 1 K2230-ub LEDLVKKkIHNANPE
0 1 S2338-p AEVVRILsTMDsPST
0 5 S2342-p RILsTMDsPST____
3661 : Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody
11818 : Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit mAb
  ACC1 iso2  
S5 ___MMWWSTLMSLLR
T6 __MMWWSTLMSLLRA
S9 MWWSTLMSLLRASSF
T24-p WRRISAEtIRIIRAL
S43 ERIMDEPSPLAKTLE
K47 DEPSPLAKTLELNQH
T48 EPSPLAKTLELNQHS
S55 TLELNQHSRFIIGSV
S61 HSRFIIGSVSEDNSE
S63 RFIIGSVSEDNSEDE
S67 GSVSEDNSEDEISNL
S72 DNSEDEISNLVKLDL
S85 DLEEKEGSLSPASVS
S87 EEKEGSLSPASVSSD
S90 EGSLSPASVSSDTLS
S92 SLSPASVSSDTLSDL
S93 LSPASVSSDTLSDLG
T95 PASVSSDTLSDLGIS
S97 SVSSDTLSDLGISGL
S114 GLAFHMRSSMSGLHL
S115 LAFHMRSSMSGLHLV
S117 FHMRSSMSGLHLVKQ
K123 MSGLHLVKQGRDRKK
S133 RDRKKIDSQRDFTVA
T195 IRFVVMVTPEDLKAN
S271 IAFMGPPSQAMWALG
K313 WQENDFSKRILNVPQ
Y323 LNVPQDLYEKGYVKD
K325 VPQDLYEKGYVKDVD
Y327 QDLYEKGYVKDVDDG
K348 VGYPVMIKASEGGGG
S381 VQAEVPGSPIFVMRL
Y454 KLAKMVGYVSAGTVE
Y471 YSQDGSFYFLELNPR
A525 GVSPWGDAPIDFENS
K557 ENPDEGFKPSSGTVQ
K557 ENPDEGFKPSSGTVQ
K616 SNMVVALKELSIRGD
T647 FQLNRIDTGWLDRLI
Y713 TVDVELIYEGIKYVL
Y771 MKEEVDRYRITIGNK
S793 NDPSVMRSPSAGKLI
Y838 VESGCIHYVKRPGAA
K862 MQLDNPSKVQQAELH
S872 QAELHTGSLPQIQST
S878 GSLPQIQSTALRGEK
Y892 KLHRVFHYVLDNLVN
Y904 LVNVMNGYCLPDPFF
S930 MKTLRDPSLPLLELQ
S944 QDIMTSVSGRIPLNV
K953 RIPLNVEKSIKKEMA
S1014 QLVQRYRSGIRGHMK
T1079 TKKNLLVTMLIDQLC
T1110 LTQLSKTTNAKVALR
S1139 LRHNQVESIFLSAID
S1143 QVESIFLSAIDMYGH
Y1148 FLSAIDMYGHQFCIE
T1233 PNRGNIPTLNRMSFA
S1238 IPTLNRMSFASNLNH
S1241 LNRMSFASNLNHYGM
Y1246 FASNLNHYGMTHVAS
T1249 NLNHYGMTHVASVSD
S1253 YGMTHVASVSDVLLD
S1255 MTHVASVSDVLLDNA
T1264 VLLDNAFTPPCQRMG
C1294 DEIMGCFCDSPPQSP
S1296 IMGCFCDSPPQSPTF
S1300 FCDSPPQSPTFPESG
T1302 DSPPQSPTFPESGHT
S1310 FPESGHTSLYDEDKV
K1353 REFTQQNKATLVEHG
K1371 LTFLVAQKDFRKQVN
K1375 VAQKDFRKQVNCEVD
C1379 DFRKQVNCEVDQRFH
Y1407 KFEEDRIYRHLEPAL
K1472 RHSDLVTKEASFEYL
Y1536 VRSMVMRYGSRLWKL
K1617 INTPYVTKDLLQSKR
K1700 EIGMVAWKMSLKSPE
K1704 VAWKMSLKSPEYPDG
S1757 RIYVAANSGARIGLA
K1786 EDPYKGYKYLYLTPQ
K1796 YLTPQDYKRVSALNS
K1796 YLTPQDYKRVSALNS
K1796 YLTPQDYKRVSALNS
K1818 DEGESRYKITDIIGK
K1825 KITDIIGKEEGLGAE
K1825 KITDIIGKEEGLGAE
S1881 RTIQVENSHLILTGA
K1893 TGAGALNKVLGREVY
K1893 TGAGALNKVLGREVY
S1945 YMPKSVHSSVPLLNS
K1953 SVPLLNSKDPIDRII
K1966 IIEFVPTKAPYDPRW
S2033 ETRTVELSIPADPAN
S2043 ADPANLDSEAKIIQQ
K2068 FKTYQAIKDFNREGL
K2068 FKTYQAIKDFNREGL
R2084 LMVFANWRGFSGGMK
K2091 RGFSGGMKDMYDQVL
T2136 SWVVIDPTINPRHME
Y2145 NPRHMEMYADRESRG
K2164 PEGTVEIKFRKKDLV
K2164 PEGTVEIKFRKKDLV
Y2181 MRRVDPVYIRLAERL
T2190 RLAERLGTPELSPTE
S2194 RLGTPELSPTERKEL
T2196 GTPELSPTERKELES
K2246 INDILDWKTSRTFFY
K2268 LEDLVKKKIHNANPE
S2376 AEVVRILSTMDSPST
S2380 RILSTMDSPST____
  human

► Hide Isoforms
 
- gap
- gap
- gap
- gap
S5-p ___MDEPsPLAQPLE
Q9 DEPsPLAQPLELNQH
P10 EPsPLAQPLELNQHS
S17 PLELNQHSRFIIGsV
S23-p HSRFIIGsVsEDNsE
S25-p RFIIGsVsEDNsEDE
S29-p GsVsEDNsEDEISNL
S34 DNsEDEISNLVKLDL
S48-p LLEEKEGsLsPAsVG
S50-p EEKEGsLsPAsVGsD
S53-p EGsLsPAsVGsDTLs
G55 sLsPAsVGsDTLsDL
S56-p LsPAsVGsDTLsDLG
T58 PAsVGsDTLsDLGIS
S60-p sVGsDTLsDLGISSL
S77-p GLALHIRssMsGLHL
S78-p LALHIRssMsGLHLV
S80-p LHIRssMsGLHLVkQ
K86-ub MsGLHLVkQGRDRKK
S96-p RDRKKIDsQRDFTVA
T158 IRFVVMVTPEDLKAN
S234-p IAFMGPPsQAMWALG
K276-ub WQENDFSkRILNVPQ
Y286-p LNVPQELyEkGyVKD
K288-ub VPQELyEkGyVKDVD
Y290-p QELyEkGyVKDVDDG
K311-ub VGYPVMIkASEGGGG
S344-p VQAEVPGsPIFVMRL
Y417-p KLAKMVGyVSAGTVE
Y434-p YSQDGSFyFLELNPR
S488-p GVSPWGDsPIDFEDS
K520 ENPDEGFKPSSGTVQ
K520-ub ENPDEGFkPSSGTVQ
K579-ub SNMVVALkELSIRGD
T610-p FQMNRIDtGWLDRLI
Y676-p TVDVELIyEGVKYVL
Y734-p MKEEVDRyRITIGNK
S756-p NDPSVMRsPSAGKLI
Y801-p VESGCIHyVKRPGAA
K825-ub MQLDNPSkVQQAELH
S835-p QAELHTGsLPRIQsT
S841-p GsLPRIQsTALRGEK
Y855-p KLHRVFHyVLDNLVN
Y867-p LVNVMNGyCLPDPFF
S893-p MKTLRDPsLPLLELQ
S907-p QDIMTSVsGRIPPNV
K916 RIPPNVEKSIKKEMA
S977-p QLVQRYRsGIRGHMK
T1042-p TKKNLLVtMLIDQLC
T1073-p LTQLSKTtNAKVALR
S1102 LRHNQVESIFLSAID
S1106 QVESIFLSAIDMyGH
Y1111-p FLSAIDMyGHQFCIE
T1196-p PNRGNIPtLNRMsFS
S1201-p IPtLNRMsFSSNLNH
S1204 LNRMsFSSNLNHyGM
Y1209-p FSSNLNHyGMTHVAs
T1212 NLNHyGMTHVAsVsD
S1216-p yGMTHVAsVsDVLLD
S1218-p MTHVAsVsDVLLDNS
T1227-p VLLDNSFtPPCQRMG
S1257-p DEVMGCFsDsPPQsP
S1259-p VMGCFsDsPPQsPtF
S1263-p FsDsPPQsPtFPEAG
T1265-p DsPPQsPtFPEAGHT
S1273-p FPEAGHTsLYDEDKV
K1316-ub REFTQQNkATLVDHG
K1334-ac LTFLVAQkDFRKQVN
K1338 VAQkDFRKQVNyEVD
Y1342-p DFRKQVNyEVDRRFH
Y1370-p KFEEDRIyRHLEPAL
K1435-ub RHSDLVTkEASFEYL
Y1499-p VRSMVMRyGSRLWKL
K1580-ac INTPYVTkDLLQSKR
K1663 EIGMVAWKMTFKSPE
K1667 VAWKMTFKSPEYPEG
S1720-p RIYVSANsGARIGLA
R1749 EDPYKGYRYLYLTPQ
K1759-ac YLTPQDYkRVSALNS
K1759-ub YLTPQDYkRVSALNS
K1759 YLTPQDYKRVSALNS
K1781 DEGESRYKITDIIGk
K1788-ac KITDIIGkEEGIGPE
K1788-ub KITDIIGkEEGIGPE
S1844-p RTIQVENsHLILTGA
K1856-ac TGAGALNkVLGREVY
K1856-ub TGAGALNkVLGREVY
S1908-p YMPKSVHsSVPLLNS
K1916-ub SVPLLNSkDPIDRII
K1929-ub IIEFVPTkTPYDPRW
S1996 ETRTVELSIPADPAN
S2006 ADPANLDSEAKIIQQ
K2031-ac FKTYQAIkDFNREGL
K2031 FKTYQAIKDFNREGL
R2047-m2 LMVFANWrGFSGGMK
K2054 rGFSGGMKDMYDQVL
S2099-p SWVVIDSsINPRHME
Y2108-p NPRHMEMyADRESRG
K2127-ac PEGTVEIkFRRKDLV
K2127 PEGTVEIKFRRKDLV
Y2144-p MRRVDPVyIHLAERL
T2153-p HLAERLGtPELSTAE
S2157 RLGtPELSTAERKEL
A2159 GtPELSTAERKELEN
K2209-ub ISDILDWkTSRTFFY
K2231 LEDLVKKKIHNANPE
S2339 AEVIRILSTMDsPST
S2343-p RILSTMDsPST____
3661 : Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody
11818 : Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit mAb
  ACC1 iso4  
S4-p ____MWWstLMsILR
T5-p ___MWWstLMsILRA
S8-p MWWstLMsILRARSF
T23 WKWISTQTVRIIRAV
S42 GGIMDEPSPLAQPLE
Q46 DEPSPLAQPLELNQH
P47 EPSPLAQPLELNQHS
S54 PLELNQHSRFIIGSV
S60 HSRFIIGSVSEDNSE
S62 RFIIGSVSEDNSEDE
S66 GSVSEDNSEDEISNL
S71 DNSEDEISNLVKLDL
S85 LLEEKEGSLSPASVG
S87 EEKEGSLSPASVGSD
S90 EGSLSPASVGSDTLS
G92 SLSPASVGSDTLSDL
S93 LSPASVGSDTLSDLG
T95 PASVGSDTLSDLGIS
S97 SVGSDTLSDLGISSL
S114 GLALHIRSSMSGLHL
S115 LALHIRSSMSGLHLV
S117 LHIRSSMSGLHLVKQ
K123 MSGLHLVKQGRDRKK
S133 RDRKKIDSQRDFTVA
T195 IRFVVMVTPEDLKAN
S271 IAFMGPPSQAMWALG
K313 WQENDFSKRILNVPQ
Y323 LNVPQELYEKGYVKD
K325 VPQELYEKGYVKDVD
Y327 QELYEKGYVKDVDDG
K348 VGYPVMIKASEGGGG
S381 VQAEVPGSPIFVMRL
Y454 KLAKMVGYVSAGTVE
Y471 YSQDGSFYFLELNPR
S525 GVSPWGDSPIDFEDS
K557 ENPDEGFKPSSGTVQ
K557 ENPDEGFKPSSGTVQ
K616 SNMVVALKELSIRGD
T647 FQMNRIDTGWLDRLI
Y713 TVDVELIYEGVKYVL
Y771 MKEEVDRYRITIGNK
S793 NDPSVMRSPSAGKLI
Y838 VESGCIHYVKRPGAA
K862 MQLDNPSKVQQAELH
S872 QAELHTGSLPRIQST
S878 GSLPRIQSTALRGEK
Y892 KLHRVFHYVLDNLVN
Y904 LVNVMNGYCLPDPFF
S930 MKTLRDPSLPLLELQ
S944 QDIMTSVSGRIPPNV
K953 RIPPNVEKSIKKEMA
S1014 QLVQRYRSGIRGHMK
T1079 TKKNLLVTMLIDQLC
T1110 LTQLSKTTNAKVALR
S1139 LRHNQVESIFLSAID
S1143 QVESIFLSAIDMYGH
Y1148 FLSAIDMYGHQFCIE
T1233 PNRGNIPTLNRMSFS
S1238 IPTLNRMSFSSNLNH
S1241 LNRMSFSSNLNHYGM
Y1246 FSSNLNHYGMTHVAS
T1249 NLNHYGMTHVASVSD
S1253 YGMTHVASVSDVLLD
S1255 MTHVASVSDVLLDNS
T1264 VLLDNSFTPPCQRMG
S1294 DEVMGCFSDSPPQSP
S1296 VMGCFSDSPPQSPTF
S1300 FSDSPPQSPTFPEAG
T1302 DSPPQSPTFPEAGHT
S1310 FPEAGHTSLYDEDKV
K1353 REFTQQNKATLVDHG
K1371 LTFLVAQKDFRKQVN
K1375 VAQKDFRKQVNYEVD
Y1379 DFRKQVNYEVDRRFH
Y1407 KFEEDRIYRHLEPAL
K1472 RHSDLVTKEASFEYL
Y1536 VRSMVMRYGSRLWKL
K1617 INTPYVTKDLLQSKR
K1700 EIGMVAWKMTFKSPE
K1704 VAWKMTFKSPEYPEG
S1757 RIYVSANSGARIGLA
R1786 EDPYKGYRYLYLTPQ
K1796 YLTPQDYKRVSALNS
K1796 YLTPQDYKRVSALNS
K1796 YLTPQDYKRVSALNS
K1818 DEGESRYKITDIIGK
K1825 KITDIIGKEEGIGPE
K1825 KITDIIGKEEGIGPE
S1881 RTIQVENSHLILTGA
K1893 TGAGALNKVLGREVY
K1893 TGAGALNKVLGREVY
S1945 YMPKSVHSSVPLLNS
K1953 SVPLLNSKDPIDRII
K1966 IIEFVPTKTPYDPRW
S2033 ETRTVELSIPADPAN
S2043 ADPANLDSEAKIIQQ
K2068 FKTYQAIKDFNREGL
K2068 FKTYQAIKDFNREGL
R2084 LMVFANWRGFSGGMK
K2091 RGFSGGMKDMYDQVL
S2136 SWVVIDSSINPRHME
Y2145 NPRHMEMYADRESRG
K2164 PEGTVEIKFRRKDLV
K2164 PEGTVEIKFRRKDLV
Y2181 MRRVDPVYIHLAERL
T2190 HLAERLGTPELSTAE
S2194 RLGTPELSTAERKEL
A2196 GTPELSTAERKELEN
K2246 ISDILDWKTSRTFFY
K2268 LEDLVKKKIHNANPE
S2376 AEVIRILSTMDSPST
S2380 RILSTMDSPST____
  rat

► Hide Isoforms
 
- gap
- gap
- gap
- gap
S5-p ___MDEPsPLAKTLE
K9 DEPsPLAKTLELNQH
T10 EPsPLAKTLELNQHS
S17 TLELNQHSRFIIGsV
S23-p HSRFIIGsVsEDNsE
S25-p RFIIGsVsEDNsEDE
S29-p GsVsEDNsEDEIsNL
S34-p DNsEDEIsNLVKLDL
S47-p DLEEKEGsLsPASVs
S49-p EEKEGsLsPASVsSD
S52 EGsLsPASVsSDTLS
S54-p sLsPASVsSDTLSDL
S55 LsPASVsSDTLSDLG
T57 PASVsSDTLSDLGIS
S59 SVsSDTLSDLGISAL
S76 GLAFHMRSsMsGLHL
S77-p LAFHMRSsMsGLHLV
S79-p FHMRSsMsGLHLVKQ
K85 MsGLHLVKQGRDRKK
S95 RDRKKIDSQRDFTVA
T157-p IRFVVMVtPEDLKAN
S233 IAFMGPPSQAMWALG
K275 WQENDFSKRILNVPQ
Y285 LNVPQDLYEKGYVKD
K287 VPQDLYEKGYVKDVD
Y289 QDLYEKGYVKDVDDG
K310 VGYPVMIKASEGGGG
S343 VQAEVPGSPIFVMRL
Y416 KLAKMVGYVSAGTVE
Y433 YSQDGSFYFLELNPR
A487 GVSPWGDAPIDFENS
K519-ac ENPDEGFkPSSGTVQ
K519 ENPDEGFKPSSGTVQ
K578 SNMVVALKELSIRGD
T609-p FQLNRIDtGWLDRLI
Y675 TVDVELIYEGIKYVL
Y733 MKEEVDRYRITIGNK
S755 NDPSVMRSPSAGKLI
Y800 VESGCIHYVKRPGAA
K824 MQLDNPSKVQQAELH
S834 QAELHTGSLPQIQST
S840 GSLPQIQSTALRGEK
Y854 KLHRVFHYVLDNLVN
Y866 LVNVMNGYCLPDPFF
S892 MKTLRDPSLPLLELQ
S906 QDIMTSVSGRIPLNV
K915 RIPLNVEKSIKKEMA
S976 QLVQRYRSGIRGHMK
T1041 TKKNLLVTMLIDQLC
T1072 LTQLSKTTNAKVALR
S1101 VRHNQVESIFLSAID
S1105 QVESIFLSAIDMYGH
Y1110 FLSAIDMYGHQFCIE
T1195-p PNRGNIPtLNRMsFA
S1200-p IPtLNRMsFASNLNH
S1203 LNRMsFASNLNHYGM
Y1208 FASNLNHYGMTHVAs
T1211 NLNHYGMTHVAsVSD
S1215-p YGMTHVAsVSDVLLD
S1217 MTHVAsVSDVLLDNA
T1226 VLLDNAFTPPCQRMG
C1256 DEVMGCFCDsPPQsP
S1258-p VMGCFCDsPPQsPTF
S1262-p FCDsPPQsPTFPESG
T1264 DsPPQsPTFPESGHT
S1272 FPESGHTSLYDEDKV
K1315 REFTQQNKATLVEHG
K1333 LTFLVAQKDFRKQVN
K1337 VAQKDFRKQVNCEVD
C1341 DFRKQVNCEVDQRFH
Y1369 KFEEDRIYRHLEPAL
K1434 RHSDLVTKEASFEYL
Y1498 VRSMVMRYGSRLWKL
K1579-ac INTPYVTkDLLQSKR
K1662 EIGMVAWKMSLKSPE
K1666 VAWKMSLKSPEYPDG
S1719 RIYVAANSGARIGLA
K1748 EDPYKGYKYLYLTPQ
K1758-ac YLTPQDYkRVSALNS
K1758 YLTPQDYKRVSALNS
K1758 YLTPQDYKRVSALNS
K1780 DEGESRYKITDIIGk
K1787-ac KITDIIGkEEGLGAE
K1787 KITDIIGKEEGLGAE
S1843 RTIQVENSHLILTGA
K1855 TGAGALNKVLGREVY
K1855 TGAGALNKVLGREVY
S1907 YMPKNVHSSVPLLNS
K1915 SVPLLNSKDPIDRII
K1928 IIEFVPTKAPYDPRW
S1995 ETRTVELSVPADPAN
S2005 ADPANLDSEAKIIQQ
K2030 FKTYQAIKDFNREGL
K2030 FKTYQAIKDFNREGL
R2046 LMVFANWRGFSGGMK
K2053 RGFSGGMKDMYDQVL
T2098 SWVVIDPTINPRHME
Y2107 NPRHMEMYADRESRG
K2126-ac PEGTVEIkFRKKDLV
K2126 PEGTVEIKFRKKDLV
Y2143 MRRVDPVYIRLAERL
T2152 RLAERLGTPELSPTE
S2156 RLGTPELSPTERKEL
T2158 GTPELSPTERKELES
K2208 INDILDWKTSRTFFY
K2230 LEDLVKKKIHSANPE
S2338 AEVVRILSTMDSPST
S2342 RILSTMDSPST____
3661 : Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody
11818 : Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit mAb
  ACC1 iso2  
- gap
- gap
- gap
- gap
S5 ___MDEPSPLAKTLE
K9 DEPSPLAKTLELNQH
T10 EPSPLAKTLELNQHS
S17 TLELNQHSRFIIGSV
S23 HSRFIIGSVSEDNSE
S25 RFIIGSVSEDNSEDE
S29 GSVSEDNSEDEISNL
S34 DNSEDEISNLVKLDL
S47 DLEEKEGSLSPASVS
S49 EEKEGSLSPASVSSD
S52 EGSLSPASVSSDTLS
S54 SLSPASVSSDTLSDL
S55 LSPASVSSDTLSDLG
T57 PASVSSDTLSDLGIS
S59 SVSSDTLSDLGISAL
S76 GLAFHMRSSMSGLHL
S77 LAFHMRSSMSGLHLV
S79 FHMRSSMSGLHLVKQ
K85 MSGLHLVKQGRDRKK
S95 RDRKKIDSQRDFTVA
T157 IRFVVMVTPEDLKAN
S233 IAFMGPPSQAMWALG
K275 WQENDFSKRILNVPQ
Y285 LNVPQDLYEKGYVKD
K287 VPQDLYEKGYVKDVD
Y289 QDLYEKGYVKDVDDG
K310 VGYPVMIKASEGGGG
S343 VQAEVPGSPIFVMRL
Y416 KLAKMVGYVSAGTVE
Y433 YSQDGSFYFLELNPR
A487 GVSPWGDAPIDFENS
K519 ENPDEGFKPSSGTVQ
K519 ENPDEGFKPSSGTVQ
K578 SNMVVALKELSIRGD
T609 FQLNRIDTGWLDRLI
Y675 TVDVELIYEGIKYVL
Y733 MKEEVDRYRITIGNK
S755 NDPSVMRSPSAGKLI
Y800 VESGCIHYVKRPGAA
K824 MQLDNPSKVQQAELH
S834 QAELHTGSLPQIQST
S840 GSLPQIQSTALRGEK
Y854 KLHRVFHYVLDNLVN
Y866 LVNVMNGYCLPDPFF
S892 MKTLRDPSLPLLELQ
S906 QDIMTSVSGRIPLNV
K915 RIPLNVEKSIKKEMA
S976 QLVQRYRSGIRGHMK
T1041 TKKNLLVTMLIDQLC
T1072 LTQLSKTTNAKVALR
S1101 VRHNQVESIFLSAID
S1105 QVESIFLSAIDMYGH
Y1110 FLSAIDMYGHQFCIE
- gap
S1192-p TSHPNRMsFASNLNH
S1195 PNRMsFASNLNHYGM
Y1200 FASNLNHYGMTHVAS
T1203 NLNHYGMTHVASVSD
S1207 YGMTHVASVSDVLLD
S1209 MTHVASVSDVLLDNA
T1218 VLLDNAFTPPCQRMG
C1248 DEVMGCFCDSPPQSP
S1250 VMGCFCDSPPQSPTF
S1254 FCDSPPQSPTFPESG
T1256 DSPPQSPTFPESGHT
S1264 FPESGHTSLYDEDKV
K1307 REFTQQNKATLVEHG
K1325 LTFLVAQKDFRKQVN
K1329 VAQKDFRKQVNCEVD
C1333 DFRKQVNCEVDQRFH
Y1361 KFEEDRIYRHLEPAL
K1426 RHSDLVTKEASFEYL
Y1490 VRSMVMRYGSRLWKL
K1571 INTPYVTKDLLQSKR
K1654 EIGMVAWKMSLKSPE
K1658 VAWKMSLKSPEYPDG
S1711 RIYVAANSGARIGLA
K1740 EDPYKGYKYLYLTPQ
K1750 YLTPQDYKRVSALNS
K1750 YLTPQDYKRVSALNS
K1750 YLTPQDYKRVSALNS
K1772 DEGESRYKITDIIGK
K1779 KITDIIGKEEGLGAE
K1779 KITDIIGKEEGLGAE
S1835 RTIQVENSHLILTGA
K1847 TGAGALNKVLGREVY
K1847 TGAGALNKVLGREVY
S1899 YMPKNVHSSVPLLNS
K1907 SVPLLNSKDPIDRII
K1920 IIEFVPTKAPYDPRW
S1987 ETRTVELSVPADPAN
S1997 ADPANLDSEAKIIQQ
K2022 FKTYQAIKDFNREGL
K2022 FKTYQAIKDFNREGL
R2038 LMVFANWRGFSGGMK
K2045 RGFSGGMKDMYDQVL
T2090 SWVVIDPTINPRHME
Y2099 NPRHMEMYADRESRG
K2118 PEGTVEIKFRKKDLV
K2118 PEGTVEIKFRKKDLV
Y2135 MRRVDPVYIRLAERL
T2144 RLAERLGTPELSPTE
S2148 RLGTPELSPTERKEL
T2150 GTPELSPTERKELES
K2200 INDILDWKTSRTFFY
K2222 LEDLVKKKIHSANPE
S2330 AEVVRILSTMDSPST
S2334 RILSTMDSPST____
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