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Protein Page:
RCAS1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
RCAS1 May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1- beta converting enzyme (ICE)-like proteases. Homodimer. By estrogen. Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Membrane protein, integral
Cellular Component: Golgi membrane; Golgi apparatus; focal adhesion; plasma membrane; integral to membrane; secretory granule
Molecular Function: apoptotic protease activator activity
Biological Process: apoptosis; regulation of cell growth
Reference #:  O00559 (UniProtKB)
Alt. Names/Synonyms: cancer associated surface antigen; Cancer-associated surface antigen RCAS1; EB9; EBAG9; estrogen receptor binding site associated, antigen, 9; Estrogen receptor-binding fragment-associated gene 9 protein; PDAF; RCAS1; Receptor-binding cancer antigen expressed on SiSo cells
Gene Symbols: EBAG9
Molecular weight: 24,377 Da
Basal Isoelectric point: 6.04  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

RCAS1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 148 S36-p SGRGRKLsGDQItLP
0 11 T41-p KLsGDQItLPTTVDy
0 46 Y48-p tLPTTVDyssVPKQT
0 21 S49-p LPTTVDyssVPKQTD
0 8 S50-p PTTVDyssVPKQTDV
0 1 S62-p TDVEEWTsWDEDAPT
0 1 T82-p GGNGNVAtQQNsLEQ
0 2 S86-p NVAtQQNsLEQLEPD
0 86 Y94-p LEQLEPDyFKDMtPt
0 4 T99-p PDyFKDMtPtIRKTQ
0 10 T101-p yFKDMtPtIRKTQKI
0 1 T134-p FSSRLAAtQDLPFIH
0 1 K202-ac KEAQRLMkKEQNKIG
  mouse

 
S36-p SGRGRKLsGDQItLP
T41-p KLsGDQItLPTTVDY
Y48 tLPTTVDYSSVPKQT
S49 LPTTVDYSSVPKQTD
S50 PTTVDYSSVPKQTDV
S62 TDVEEWTSWDEDAPT
T82 GGNGNVATQQNSLEQ
S86 NVATQQNSLEQLEPD
Y94 LEQLEPDYFKDMTPT
T99 PDYFKDMTPTIRKTQ
T101 YFKDMTPTIRKTQKI
T134 FSSRLAATQDMPFIH
K202 KEAQRLMKKEQNKIG
  rat

 
S36-p SGRGRKLsGDQITLP
T41 KLsGDQITLPTTVDY
Y48 TLPTTVDYSSVPKQT
S49 LPTTVDYSSVPKQTD
S50 PTTVDYSSVPKQTDV
S62 TDVEEWTSWDEDAPT
A82 GGTGNAAAQQNSLEQ
S86 NAAAQQNSLEQLEPD
Y94 LEQLEPDYFKDMTPT
T99 PDYFKDMTPTIRKTQ
T101 YFKDMTPTIRKTQKI
T134 FSSRLAATQDMPFIH
K202 KEAQRLLKKEQNKMG
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