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Protein Page:
Afadin (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
Afadin plays a role in adhesion by participating, along with E-cadherin and catenin, in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Essential for the association of nectin and E-cadherin. Contains 1 forkhead-associated (FHA) domain, a phosphopeptide recognition domain; 1 dilute (DIL) domain, a myosin-like domain which may play a functional role in cellular processes or vectorial vesicle transport; 1 PDZ domain, which frequently binds the carboxyl-terminal sequences of proteins or phosphatidylinositol 4,5-bisphosphate in the plasma membrane; and 2 RA domains, which are associated with RasGTP effector activity. Five alternatively spliced isoforms have been described. Isoform 2 does not interact with F-actin. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Cell adhesion
Cellular Component: cell-cell adherens junction; apical part of cell; cytoplasm; plasma membrane; nucleolus; intercellular junction; cytosol; cell junction; nucleus
Molecular Function: protein C-terminus binding; protein binding; cell adhesion molecule binding
Biological Process: intercellular junction assembly and maintenance; cell-cell signaling; signal transduction; cell adhesion
Reference #:  P55196 (UniProtKB)
Alt. Names/Synonyms: AF-6; AF6; AFAD; Afadin; ALL1-fused gene from chromosome 6 protein; FLJ34371; MLLT4; myeloid/lymphoid or mixed-lineage leukemia, translocated to, 4; Protein AF-6; RP3-431P23.3; translocated to, 4
Gene Symbols: MLLT4
Molecular weight: 206,804 Da
Basal Isoelectric point: 6.06  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

Afadin

Protein Structure Not Found.


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Sites Implicated In
molecular association, regulation: T909‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 K90 MRMLSSPKYSLyEVH
0 1 Y91 RMLSSPKYSLyEVHV
0 110 Y94-p SSPKYSLyEVHVSGE
0 2 T160-p VIQNFKRtLsKKEKK
0 2 S162-p QNFKRtLsKKEKKEK
0 1 S181-p KEALRQAsDKDDRPF
0 17 Y203-p SRLAAEVyKDMPETs
0 1 S210-p yKDMPETsFTRTIsN
0 1 T214 PETsFTRTIsNPEVV
0 57 S216-p TsFTRTIsNPEVVMK
0 4 S246-p SSDGRPDsGGtLRIy
0 4 T249-p GRPDsGGtLRIyADs
0 2 Y253-p sGGtLRIyADsLKPN
0 1 S256-p tLRIyADsLKPNIPy
0 1 K258 RIyADsLKPNIPyKT
0 26 Y263-p sLKPNIPyKTILLST
0 1 Y295-p EKENPKDyCIARVML
0 1 K315 HSDEKGAKEIILDDD
0 1 K336 FREWPSDKGILVFQL
0 1 K336 FREWPSDKGILVFQL
0 1 T363 KKHLEGKTPKGKERA
0 2 S373 GKERADGSGyGSTLP
0 10 Y375-p ERADGSGyGSTLPPE
0 1 K383 GSTLPPEKLPYLVEL
0 5 S391 LPYLVELSPGRRNHF
0 1 Y401 RRNHFAYYNYHTYED
0 6 S424-p KLYRLQLsVTEVGTE
0 1 T430 LsVTEVGTEKLDDNS
0 3 S512-p DHALAKRsVDGGLMV
0 1 S551-p TALPTSKsTTRLDsD
0 1 T552 ALPTSKsTTRLDsDR
0 7 S557-p KsTTRLDsDRVssAs
0 4 S561-p RLDsDRVssAsstAE
0 7 S562-p LDsDRVssAsstAER
0 2 S564-p sDRVssAsstAERGM
0 3 S565-p DRVssAsstAERGMV
0 4 T566-p RVssAsstAERGMVK
0 40 Y584-p RVEQQPDyRRQEsRT
0 2 S589-p PDyRRQEsRTQDASG
0 5 S655-p NQYRPDIsPTERTHK
0 1 S672-p AVVNKMVsMMEGVIQ
1 0 T909-p VVTVAENtADELARS
0 1 S973-p RLIPHTRsPGtWTIy
0 1 T976-p PHTRsPGtWTIyFEG
0 2 Y980-p sPGtWTIyFEGADyE
0 18 Y986-p IyFEGADyESHLLRE
0 1 T995-p SHLLRENtELAQPLR
0 1 K1013 EIITVTLKKQNGMGL
0 1 K1026 GLSIVAAKGAGQDKL
0 1 K1032 AKGAGQDKLGIYVKS
0 1 K1042 IYVKSVVKGGAADVD
0 4 T1081-p AAELMTRtSsVVtLE
0 44 S1083-p ELMTRtSsVVtLEVA
0 1 T1086-p TRtSsVVtLEVAKQG
0 1 Y1096-p VAKQGAIyHGLAtLL
0 1 T1101-p AIyHGLAtLLNQPsP
0 57 S1107-p AtLLNQPsPMMQRIS
0 19 S1126-p SGKPRPKsEGFELyN
0 6 Y1132-p KsEGFELyNNstQNG
0 1 S1135-p GFELyNNstQNGsPE
0 1 T1136-p FELyNNstQNGsPEs
0 3 S1140-p NNstQNGsPEsPQLP
0 5 S1143-p tQNGsPEsPQLPWAE
0 2 Y1151-p PQLPWAEySEPKKLP
0 33 S1172-p KNRADHRssPNVANQ
0 26 S1173-p NRADHRssPNVANQP
0 81 S1182-p NVANQPPsPGGKsAy
0 2 S1187-p PPsPGGKsAyASGTt
0 5 Y1189-p sPGGKsAyASGTtAK
0 1 S1191 GGKsAyASGTtAKIT
0 1 T1194-p sAyASGTtAKITsVs
0 3 S1199-p GTtAKITsVstGNLC
0 8 S1201-p tAKITsVstGNLCtE
0 2 T1202-p AKITsVstGNLCtEE
0 5 T1207-p VstGNLCtEEQtPPP
0 15 T1211-p NLCtEEQtPPPRPEA
0 3 Y1219-p PPPRPEAyPIPTQTy
0 4 Y1226-p yPIPTQTyTREyFtF
0 100 Y1230-p TQTyTREyFtFPAsK
0 48 T1232-p TyTREyFtFPAsKsQ
0 2 S1236-p EyFtFPAsKsQDRMA
0 1 K1237 yFtFPAsKsQDRMAP
0 3 S1238-p FtFPAsKsQDRMAPP
0 2 Y1252-p PQNQWPNyEEKPHMH
0 1 T1260 EEKPHMHTDSNHSSI
0 17 S1275-p AIQRVTRsQEELRED
0 32 Y1285-p ELREDKAyQLERHRI
0 1 S1300-p EAAMDRKsDSDMWIN
0 3 S1328-p HLNHSSKsVtPAStL
0 10 T1330-p NHSSKsVtPAStLTK
0 2 T1334-p KsVtPAStLTKSGPG
0 1 T1336 VtPAStLTKSGPGRW
0 1 K1337 tPAStLTKSGPGRWK
1 2 T1352-p TPAAIPAtPVAVSQP
0 2 Y1419-p REEHQRWyEKEKARL
0 10 S1455-p SLNPAPFsPLtAQQM
0 1 T1458-p PAPFsPLtAQQMKPE
0 3 T1489-p QPQQQPRtIERRDLQ
0 168 Y1497-p IERRDLQyItVsKEE
0 3 T1499-p RRDLQyItVsKEELS
0 8 S1501-p DLQyItVsKEELSSG
0 10 S1512-p LSSGDSLsPDPWKRD
0 73 Y1656-p KRRQEEGyysRLEAE
0 113 Y1657-p RRQEEGyysRLEAER
0 4 S1658-p RQEEGyysRLEAERR
0 10 Y1692-p RPPLPRDyEPPsPsP
0 4 S1696-p PRDyEPPsPsPAPGA
0 2 S1698-p DyEPPsPsPAPGAPP
0 1 K1716 QRNASYLKTQVLsPD
0 20 S1721-p YLKTQVLsPDSLFTA
0 1 S1753 GPNSYPGSTGAAVGA
0 1 H1761 TGAAVGAHDACRDAK
0 7 S1774-p AKEKRSKsQDADsPG
0 12 S1779-p SKsQDADsPGssGAP
0 6 S1782-p QDADsPGssGAPENL
0 2 S1783-p DADsPGssGAPENLT
0 297 S1799-p KERQRLFsQGQDVsN
0 1 S1805-p FsQGQDVsNKVKASR
0 49 T1815-p VKASRKLtELENELN
0 1 T1823-p ELENELNtK______
0 1 K1824 LENELNtK_______
  Afadin iso2  
K90 MRMLSSPKYSLYEVH
Y91 RMLSSPKYSLYEVHV
Y94 SSPKYSLYEVHVSGE
T159 VIQNFKRTLSKKEKK
S161 QNFKRTLSKKEKKEK
S180 KEALRQASDKDDRPF
Y202 SRLAAEVYKDMPETS
S209 YKDMPETSFTRTISN
T213 PETSFTRTISNPEVV
S215 TSFTRTISNPEVVMK
S245 SSDGRPDSGGTLRIY
T248 GRPDSGGTLRIYADS
Y252 SGGTLRIYADSLKPN
S255 TLRIYADSLKPNIPY
K257 RIYADSLKPNIPYKT
Y262 SLKPNIPYKTILLST
Y294 EKENPKDYCIARVML
K314 HSDEKGAKEIILDDD
K335 FREWPSDKGILVFQL
K335 FREWPSDKGILVFQL
T362 KKHLEGKTPKGKERA
S372 GKERADGSGyGSTLP
Y374-p ERADGSGyGSTLPPE
K382 GSTLPPEKLPYLVEL
S390-p LPYLVELsPDGSDSR
- gap
S408 KLYRLQLSVTEVGTE
T414 LSVTEVGTEKLDDNS
S496 DHALAKRSVDGGLMV
S535 TALPTSKSTTRLDSD
T536 ALPTSKSTTRLDSDR
S541 KSTTRLDSDRVSSAS
S545 RLDSDRVSSASSTAE
S546 LDSDRVSSASSTAER
S548 SDRVSSASSTAERGM
S549 DRVSSASSTAERGMV
T550 RVSSASSTAERGMVK
Y568 RVEQQPDYRRQESRT
S573 PDYRRQESRTQDASG
S639 NQYRPDISPTERTHK
S656 AVVNKMVSMMEGVIQ
T893 VVTVAENTADELARS
S957 RLIPHTRSPGTWTIY
T960 PHTRSPGTWTIYFEG
Y964 SPGTWTIYFEGADYE
Y970 IYFEGADYESHLLRE
T979 SHLLRENTELAQPLR
K997 EIITVTLKKQNGMGL
K1010 GLSIVAAKGAGQDKL
K1016 AKGAGQDKLGIYVKS
K1026 IYVKSVVKGGAADVD
T1065 AAELMTRTSSVVTLE
S1067 ELMTRTSSVVTLEVA
T1070 TRTSSVVTLEVAKQG
Y1080 VAKQGAIYHGLATLL
T1085 AIYHGLATLLNQPSP
S1091 ATLLNQPSPMMQRIS
S1110 SGKPRPKSEGFELYN
Y1116 KSEGFELYNNSTQNG
S1119 GFELYNNSTQNGSPE
T1120 FELYNNSTQNGSPES
S1124 NNSTQNGSPESPQLP
S1127 TQNGSPESPQLPWAE
Y1135 PQLPWAEYSEPKKLP
S1156 KNRADHRSSPNVANQ
S1157 NRADHRSSPNVANQP
S1166 NVANQPPSPGGKSAY
S1171 PPSPGGKSAYASGTT
Y1173 SPGGKSAYASGTTAK
S1175 GGKSAYASGTTAKIT
T1178 SAYASGTTAKITSVS
S1183 GTTAKITSVSTGNLC
S1185 TAKITSVSTGNLCTE
T1186 AKITSVSTGNLCTEE
T1191 VSTGNLCTEEQTPPP
T1195 NLCTEEQTPPPRPEA
Y1203 PPPRPEAYPIPTQTY
Y1210 YPIPTQTYTREYFTF
Y1214 TQTYTREYFTFPASK
T1216 TYTREYFTFPASKSQ
S1220 EYFTFPASKSQDRMA
K1221 YFTFPASKSQDRMAP
S1222 FTFPASKSQDRMAPP
Y1236 PQNQWPNYEEKPHMH
T1244 EEKPHMHTDSNHSSI
S1259 AIQRVTRSQEELRED
Y1269 ELREDKAYQLERHRI
S1284 EAAMDRKSDSDMWIN
S1312 HLNHSSKSVTPASTL
T1314 NHSSKSVTPASTLTK
T1318 KSVTPASTLTKSGPG
T1320 VTPASTLTKSGPGRW
K1321 TPASTLTKSGPGRWK
T1336 TPAAIPATPVAVSQP
Y1403 REEHQRWYEKEKARL
S1439 SLNPAPFSPLTAQQM
T1442 PAPFSPLTAQQMKPE
T1473 QPQQQPRTIERRDLQ
Y1481 IERRDLQYITVSKEE
T1483 RRDLQYITVSKEELS
S1485 DLQYITVSKEELSSG
S1496 LSSGDSLSPDPWKRD
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- under review  
- gap
- gap
- gap
  Afadin iso3  
K90 MRMLSSPKYSLyEVH
Y91 RMLSSPKYSLyEVHV
Y94-p SSPKYSLyEVHVSGE
T159 VIQNFKRTLSKKEKK
S161 QNFKRTLSKKEKKEK
S180 KEALRQASDKDDRPF
Y202 SRLAAEVYKDMPETS
S209 YKDMPETSFTRTISN
T213 PETSFTRTISNPEVV
S215 TSFTRTISNPEVVMK
S245 SSDGRPDSGGTLRIY
T248 GRPDSGGTLRIYADS
Y252 SGGTLRIYADSLKPN
S255 TLRIYADSLKPNIPY
K257 RIYADSLKPNIPYKT
Y262 SLKPNIPYKTILLST
Y294 EKENPKDYCIARVML
K314 HSDEKGAKEIILDDD
K335 FREWPSDKGILVFQL
K335 FREWPSDKGILVFQL
T362 KKHLEGKTPKGKERA
S372-p GKERADGsGyGSTLP
Y374-p ERADGsGyGSTLPPE
K382 GSTLPPEKLPYLVEL
S390-p LPYLVELsPDGSDSR
- gap
S408 KLYRLQLSVTEVGTE
T414 LSVTEVGTEKLDDNS
S496 DHALAKRSVDGGLMV
S535 TALPTSKSTTRLDSD
T536 ALPTSKSTTRLDSDR
S541 KSTTRLDSDRVSSAS
S545 RLDSDRVSSASSTAE
S546 LDSDRVSSASSTAER
S548 SDRVSSASSTAERGM
S549 DRVSSASSTAERGMV
T550 RVSSASSTAERGMVK
Y568 RVEQQPDYRRQESRT
S573 PDYRRQESRTQDASG
S639 NQYRPDISPTERTHK
S656 AVVNKMVSMMEGVIQ
T893 VVTVAENTADELARS
S957 RLIPHTRSPGTWTIY
T960 PHTRSPGTWTIYFEG
Y964 SPGTWTIYFEGADYE
Y970 IYFEGADYESHLLRE
T979 SHLLRENTELAQPLR
K997 EIITVTLKKQNGMGL
K1010 GLSIVAAKGAGQDKL
K1016 AKGAGQDKLGIYVKS
K1026 IYVKSVVKGGAADDG
T1064 AAELMTRTSSVVTLE
S1066 ELMTRTSSVVTLEVA
T1069 TRTSSVVTLEVAKQG
Y1079 VAKQGAIYHGLATLL
T1084 AIYHGLATLLNQPsP
S1090-p ATLLNQPsPMMQRIS
S1109-p SGKPRPKsEGFELYN
Y1115 KsEGFELYNNSTQNG
S1118 GFELYNNSTQNGSPE
T1119 FELYNNSTQNGSPES
S1123 NNSTQNGSPESPQLP
S1126 TQNGSPESPQLPWAE
Y1134 PQLPWAEYSEPKKLP
S1155 KNRADHRSSPNVANQ
S1156 NRADHRSSPNVANQP
S1165 NVANQPPSPGGKSAY
S1170 PPSPGGKSAYASGTT
Y1172 SPGGKSAYASGTTAK
S1174 GGKSAYASGTTAKIT
T1177 SAYASGTTAKITSVS
S1182 GTTAKITSVSTGNLC
S1184 TAKITSVSTGNLCTE
T1185 AKITSVSTGNLCTEE
T1190 VSTGNLCTEEQTPPP
T1194 NLCTEEQTPPPRPEA
Y1202 PPPRPEAYPIPTQTY
Y1209 YPIPTQTYTREyFTF
Y1213-p TQTYTREyFTFPASK
T1215 TYTREyFTFPASKSQ
S1219 EyFTFPASKSQDRMA
K1220 yFTFPASKSQDRMAP
S1221 FTFPASKSQDRMAPP
Y1235 PQNQWPNYEEKPHMH
T1243 EEKPHMHTDSNHSSI
S1258 AIQRVTRSQEELRED
Y1268-p ELREDKAyQLERHRI
S1283 EAAMDRKSDSDMWIN
S1311 HLNHSSKSVTPASTL
T1313 NHSSKSVTPASTLTK
T1317 KSVTPASTLTKSGPG
T1319 VTPASTLTKSGPGRW
K1320 TPASTLTKSGPGRWK
T1335 TPAAIPATPVAVSQP
Y1402 REEHQRWYEKEKARL
S1438 SLNPAPFSPLTAQQM
T1441 PAPFSPLTAQQMKPE
T1472 QPQQQPRTIERRDLQ
Y1480-p IERRDLQyITVSKEE
T1482 RRDLQyITVSKEELS
S1484 DLQyITVSKEELSSG
S1495 LSSGDSLSPDPWKRD
Y1639-p KRRQEEGyYSRLEAE
Y1640 RRQEEGyYSRLEAER
S1641 RQEEGyYSRLEAERR
- gap
- gap
- gap
- gap
- gap
S1672-p GPNSYPGsTGAAVGA
H1680 TGAAVGAHDACRDAK
S1693 AKEKRSKSQDADsPG
S1698-p SKSQDADsPGssGAP
S1701-p QDADsPGssGAPENL
S1702-p DADsPGssGAPENLT
S1718-p KERQRLFsQGQDVSN
S1724 FsQGQDVSNKVKASR
T1734-p VKASRKLtELENELN
T1742 ELENELNTK______
K1743 LENELNTK_______
5485 : Phospho-Afadin (Ser1718) Antibody
  mouse

► Hide Isoforms
 
K90-ub MRMLSSPkySLyEVH
Y91-p RMLSSPkySLyEVHV
Y94-p SSPkySLyEVHVSGE
T160 VIQNFKRTLSKKEKK
S162 QNFKRTLSKKEKKEK
S181 KEALRQASDKEERPS
Y203-p SRLAAEVyKDMPETS
S210 yKDMPETSFTRtIsN
T214-p PETSFTRtIsNPEVV
S216-p TSFTRtIsNPEVVMK
S246-p SSDGRPDsGGtLRIy
T249-p GRPDsGGtLRIyADS
Y253-p sGGtLRIyADSLkPN
S256 tLRIyADSLkPNIPY
K258-ub RIyADSLkPNIPYKT
Y263 SLkPNIPYKTILLST
Y295 EKENPKDYCIARVML
K315-ub HSDERGAkEIILDDD
K336-ac FREWPSDkGILVFQL
K336-ub FREWPSDkGILVFQL
S363-p KKHVEGKsLKGKDRA
S373 GKDRADGSGYGSALP
Y375 DRADGSGYGSALPPE
K383 GSALPPEKLPYLVEL
S391-p LPYLVELsPGRRNHF
Y401-p RRNHFAYySYHTYED
S424-p KLYRLQLsVTEVGtE
T430-p LsVTEVGtEKFDDNS
S512-p DHVLSKRsVDGGLMV
S551-p TALPASRstTRLDsD
T552-p ALPASRstTRLDsDR
S557-p RstTRLDsDRVssAs
S561-p RLDsDRVssAsstAE
S562-p LDsDRVssAsstAER
S564-p sDRVssAsstAERGM
S565-p DRVssAsstAERGMV
T566-p RVssAsstAERGMVK
Y584-p RLDQEQEyRRRENRT
N589 QEyRRRENRTQDATG
S655-p SQHRPDIsPTERTHK
S672 AVVNKMVSMMEGVIQ
T909 VVAVAENTADELARS
S973 RLVPHTRSPGTWTIY
T976 PHTRSPGTWTIYFEG
Y980 SPGTWTIYFEGADYE
Y986 IYFEGADYESHLMRE
A995 SHLMRENAELAQPLR
K1013-ub EIITVTLkKQNGMGL
K1026-ac GLSIVAAkGAGQDkL
K1032-ac AkGAGQDkLGIYVKS
K1042-ub IYVKSVVkGGAADVD
T1081-p AAELMTRtSsVVtLE
S1083-p ELMTRtSsVVtLEVA
T1086-p TRtSsVVtLEVAKQG
Y1096 VAKQGAIYHGLATLL
T1101 AIYHGLATLLNQPsP
S1107-p ATLLNQPsPMMQRIS
S1126-p SGKPRPKsEGFELyN
Y1132-p KsEGFELyNNsAQNG
S1135-p GFELyNNsAQNGsPE
A1136 FELyNNsAQNGsPEs
S1140-p NNsAQNGsPEsPQMP
S1143-p AQNGsPEsPQMPWTE
Y1151 PQMPWTEYSEPKKLP
S1172-p KNRADHRssPNVANQ
S1173-p NRADHRssPNVANQP
S1182-p NVANQPPsPGGKGPy
G1187 PPsPGGKGPyTsGTA
Y1189-p sPGGKGPyTsGTAAK
S1191-p GGKGPyTsGTAAKIT
A1194 GPyTsGTAAKITsVs
S1199-p GTAAKITsVstGNLC
S1201-p AAKITsVstGNLCtE
T1202-p AKITsVstGNLCtEE
T1207-p VstGNLCtEEQsPPP
S1211-p NLCtEEQsPPPRPEA
Y1219-p PPPRPEAyPIPTQTY
Y1226 yPIPTQTYTREyFtF
Y1230-p TQTYTREyFtFPAsk
T1232-p TYTREyFtFPAsksQ
S1236-p EyFtFPAsksQDRMA
K1237-ub yFtFPAsksQDRMAP
S1238-p FtFPAsksQDRMAPP
Y1252 PQSQWPNYEEKPHVH
T1260-p EEKPHVHtESNHSSI
S1275-p AIQRVTRsQEELREE
Y1285-p ELREEKVyQLERHRV
C1300 EAGMDRKCDSDMWIN
S1328-p HLNHSSKsVtPAStL
T1330-p NHSSKsVtPAStLtk
T1334-p KsVtPAStLtkSGPG
T1336-p VtPAStLtkSGPGRW
K1337-ub tPAStLtkSGPGRWK
T1352 TPAAVLPTPVAVSQP
Y1418 REEHQRWYEKEKARL
S1454 TLNPASFSPLATQAK
- gap
T1487 QPQQQPRTIERKDLQ
Y1495-p IERKDLQyItIsKEE
T1497-p RKDLQyItIsKEELS
S1499-p DLQyItIsKEELSSG
S1510-p LSSGDSLsPDPWKRD
Y1654-p KRRQEEGyYSRLEAE
Y1655 RRQEEGyYSRLEAER
S1656 RQEEGyYSRLEAERR
Y1690 RPPLPRDYEPPSLSS
S1694 PRDYEPPSLSSAPCA
S1696 DYEPPSLSSAPCAPP
K1714-ub QRNASYLkTQVLsPD
S1719-p YLkTQVLsPDSLFTA
S1749 GPNSYSGSAGTAVGA
Y1757-p AGTAVGAyDAPREAR
S1770-p AREKLTRsQDADLPG
L1775 TRsQDADLPGSSGAP
S1778 QDADLPGSSGAPENL
S1779 DADLPGSSGAPENLT
S1795-p KERQRLFsQGQDVSD
S1801 FsQGQDVSDKVKASR
T1811-p VKASRKLtELENELN
T1819 ELENELNTk______
K1820-ac LENELNTk_______
5485 : Phospho-Afadin (Ser1718) Antibody
  Afadin iso2  
K90 MRMLSSPKYSLYEVH
Y91 RMLSSPKYSLYEVHV
Y94 SSPKYSLYEVHVSGE
T160 VIQNFKRTLSKKEKK
S162 QNFKRTLSKKEKKEK
S181 KEALRQASDKEERPS
Y203 SRLAAEVYKDMPETS
S210 YKDMPETSFTRTISN
T214 PETSFTRTISNPEVV
S216 TSFTRTISNPEVVMK
S246 SSDGRPDSGGTLRIY
T249 GRPDSGGTLRIYADS
Y253 SGGTLRIYADSLKPN
S256 TLRIYADSLKPNIPY
K258 RIYADSLKPNIPYKT
Y263 SLKPNIPYKTILLST
Y295 EKENPKDYCIARVML
K315 HSDERGAKEIILDDD
K336 FREWPSDKGILVFQL
K336 FREWPSDKGILVFQL
S363 KKHVEGKSLKGKDRA
S373 GKDRADGSGYGSALP
Y375 DRADGSGYGSALPPE
K383-ub GSALPPEkLPYLVEL
S391 LPYLVELSPDGSDSR
- gap
S409 KLYRLQLSVTEVGTE
T415 LSVTEVGTEKFDDNS
S497 DHVLSKRSVDGGLMV
S536 TALPASRSTTRLDSD
T537 ALPASRSTTRLDSDR
S542 RSTTRLDSDRVSSAS
S546 RLDSDRVSSASSTAE
S547 LDSDRVSSASSTAER
S549 SDRVSSASSTAERGM
S550 DRVSSASSTAERGMV
T551 RVSSASSTAERGMVK
Y569 RLDQEQEYRRRENRT
N574 QEYRRRENRTQDATG
S640 SQHRPDISPTERTHK
S657 AVVNKMVSMMEGVIQ
T894 VVAVAENTADELARS
S958 RLVPHTRSPGTWTIY
T961 PHTRSPGTWTIYFEG
Y965 SPGTWTIYFEGADYE
Y971 IYFEGADYESHLMRE
A980 SHLMRENAELAQPLR
K998 EIITVTLKKQNGMGL
K1011 GLSIVAAKGAGQDKL
K1017 AKGAGQDKLGIYVKS
K1027 IYVKSVVKGGAADVD
T1066 AAELMTRTSSVVTLE
S1068 ELMTRTSSVVTLEVA
T1071 TRTSSVVTLEVAKQG
Y1081 VAKQGAIYHGLATLL
T1086 AIYHGLATLLNQPSP
S1092 ATLLNQPSPMMQRIS
S1111 SGKPRPKSEGFELYN
Y1117 KSEGFELYNNSAQNG
S1120 GFELYNNSAQNGSPE
A1121 FELYNNSAQNGSPES
S1125 NNSAQNGSPESPQMP
S1128 AQNGSPESPQMPWTE
Y1136 PQMPWTEYSEPKKLP
S1157 KNRADHRSSPNVANQ
S1158 NRADHRSSPNVANQP
S1167 NVANQPPSPGGKGPY
G1172 PPSPGGKGPYTSGTA
Y1174 SPGGKGPYTSGTAAK
S1176 GGKGPYTSGTAAKIT
A1179 GPYTSGTAAKITSVS
S1184 GTAAKITSVSTGNLC
S1186 AAKITSVSTGNLCTE
T1187 AKITSVSTGNLCTEE
T1192 VSTGNLCTEEQSPPP
S1196 NLCTEEQSPPPRPEA
Y1204 PPPRPEAYPIPTQTY
Y1211 YPIPTQTYTREYFTF
Y1215 TQTYTREYFTFPASK
T1217 TYTREYFTFPASKSQ
S1221 EYFTFPASKSQDRMA
K1222 YFTFPASKSQDRMAP
S1223 FTFPASKSQDRMAPP
Y1237 PQSQWPNYEEKPHVH
T1245 EEKPHVHTESNHSSI
S1260 AIQRVTRSQEELREE
Y1270 ELREEKVYQLERHRV
C1285 EAGMDRKCDSDMWIN
S1313 HLNHSSKSVTPASTL
T1315 NHSSKSVTPASTLTK
T1319 KSVTPASTLTKSGPG
T1321 VTPASTLTKSGPGRW
K1322 TPASTLTKSGPGRWK
T1337 TPAAVLPTPVAVSQP
Y1403 REEHQRWYEKEKARL
S1439 TLNPASFSPLATQAK
- gap
T1472 QPQQQPRTIERKDLQ
Y1480 IERKDLQYITISKEE
T1482 RKDLQYITISKEELS
S1484 DLQYITISKEELSSG
S1495 LSSGDSLSPDPWKRD
Y1639 KRRQEEGYYSRLEAE
Y1640 RRQEEGYYSRLEAER
S1641 RQEEGYYSRLEAERR
Y1675 RPPLPRDYEPPSLSS
S1679 PRDYEPPSLSSAPCA
S1681 DYEPPSLSSAPCAPP
K1699 QRNASYLKTQVLSPD
S1704 YLKTQVLSPDSLFTA
S1734 GPNSYSGSAGTAVGA
Y1742 AGTAVGAYDAPREAR
S1755 AREKLTRSQDADLPG
L1760 TRSQDADLPGSSGAP
S1763 QDADLPGSSGAPENL
S1764 DADLPGSSGAPENLT
S1780 KERQRLFSQGQDVSD
S1786 FSQGQDVSDKVKASR
T1796 VKASRKLTELENELN
T1804 ELENELNTK______
K1805 LENELNTK_______
5485 : Phospho-Afadin (Ser1718) Antibody
  rat

 
K90 MRMLSSPKYSLYEVH
Y91 RMLSSPKYSLYEVHV
Y94 SSPKYSLYEVHVSGE
T160 VIQNFKRTLSKKEKK
S162 QNFKRTLSKKEKKEK
S181 KEALRQASDKEERPS
Y203 SRLAAEVYKDMPETS
S210 YKDMPETSFTRTIsN
T214 PETSFTRTIsNPEVV
S216-p TSFTRTIsNPEVVMK
S246 SSDGRPDSGGTLRIY
T249 GRPDSGGTLRIYADS
Y253 SGGTLRIYADSLKPN
S256 TLRIYADSLKPNIPY
K258 RIYADSLKPNIPYKT
Y263 SLKPNIPYKTILLST
Y295 EKENPKDYCIARVML
K315 HSDERGAKEIILDDD
K336-ac FREWPSDkGILVFQL
K336 FREWPSDKGILVFQL
P363 KKHVEGKPLKGKDRA
S373 GKDRADGSGYGSALP
Y375 DRADGSGYGSALPPE
K383 GSALPPEKLPYLVEL
S391-p LPYLVELsPGRRNHF
Y401 RRNHFAYYSYHTYED
S424 KLYRLQLSVTEVGTE
T430 LSVTEVGTEKFDDNS
S512-p DHVLSKRsVDGGLMV
S551 TALPASRSTTRLDsD
T552 ALPASRSTTRLDsDR
S557-p RSTTRLDsDRVSSAS
S561 RLDsDRVSSASSTAE
S562 LDsDRVSSASSTAER
S564 sDRVSSASSTAERGM
S565 DRVSSASSTAERGMV
T566 RVSSASSTAERGMVK
Y584 RLDQEQDYRRREsRT
S589-p QDYRRREsRTQDAAG
S655 SQHRPDISPTERTHK
S672 AVVNKMVSMMEGVIQ
T916 VVAVAENTADELARS
S980 RLVPHTRSPGTWTIY
T983 PHTRSPGTWTIYFEG
Y987 SPGTWTIYFEGADYE
Y993 IYFEGADYESHLMRE
T1002 SHLMRENTELTQPLR
K1020 EVITVTLKKQNGMGL
K1033 GLSIVAAKGAGQDKL
K1039 AKGAGQDKLGIYVKS
K1049 IYVKSVVKGGAADVD
T1088 AAELMTRTSsVVTLE
S1090-p ELMTRTSsVVTLEVA
T1093 TRTSsVVTLEVAKQG
Y1103 VAKQGAIYHGLATLL
T1108 AIYHGLATLLNQPsP
S1114-p ATLLNQPsPMMQRIS
S1133 SGKPRPKSEGFELYN
Y1139 KSEGFELYNNSAQNG
S1142 GFELYNNSAQNGsPE
A1143 FELYNNSAQNGsPEs
S1147-p NNSAQNGsPEsPQMP
S1150-p AQNGsPEsPQMPWTE
Y1158 PQMPWTEYSEPKKLP
S1179-p KNRADHRssPNVANQ
S1180-p NRADHRssPNVANQP
S1189-p NVANQPPsPGGKSPY
S1194 PPsPGGKSPYTSGTA
Y1196 sPGGKSPYTSGTAAK
S1198 GGKSPYTSGTAAKIT
A1201 SPYTSGTAAKITSVS
S1206 GTAAKITSVSTGNLC
S1208 AAKITSVSTGNLCTE
T1209 AKITSVSTGNLCTEE
T1214 VSTGNLCTEEQtPPP
T1218-p NLCTEEQtPPPRPEA
Y1226 PPPRPEAYPIPTQTY
Y1233 YPIPTQTYTREYFTF
Y1237 TQTYTREYFTFPASK
T1239 TYTREYFTFPASKSQ
S1243 EYFTFPASKSQDRMA
K1244 YFTFPASKSQDRMAP
S1245 FTFPASKSQDRMAPV
Y1259 VQNQWPNYEEKPHMH
T1267 EEKPHMHTESDHASI
S1282-p AIQRVTRsQEELREE
Y1292-p ELREEKVyQLERHRV
C1307 ESGMDRKCDSDMWIN
S1335 HLNHSSKSVTPASTL
T1337 NHSSKSVTPASTLTK
T1341 KSVTPASTLTKSGPG
T1343 VTPASTLTKSGPGRW
K1344 TPASTLTKSGPGRWK
T1359 TPAAVLPTPVAVSQP
Y1425 REEHQRWYEKEKARL
S1461 SLNPASFSPLATQAK
- gap
T1494 QPQQQPRTIERRDLQ
Y1502 IERRDLQYITIsKEE
T1504 RRDLQYITIsKEELS
S1506-p DLQYITIsKEELSSG
S1517-p LSSGDSLsPDPWKRD
Y1661 KRRQEEGYYSRLEAE
Y1662 RRQEEGYYSRLEAER
S1663 RQEEGYYSRLEAERR
Y1697 RPPLPQDYEPPSQSS
S1701 PQDYEPPSQSSAPSA
S1703 DYEPPSQSSAPSAPP
K1721 QRNASYLKTQVLsPD
S1726-p YLKTQVLsPDSLFTA
S1758 GPNSYSGSAGTTAGT
Y1766 AGTTAGTYDAPRDTR
S1779-p TREKLSRsQDADLPG
L1784 SRsQDADLPGSSGAP
S1787 QDADLPGSSGAPENL
S1788 DADLPGSSGAPENLT
S1804-p RERQRLFsQGQDVSD
S1810 FsQGQDVSDKVKASR
T1820 VKASRKLTELENELN
T1828 ELENELNTK______
K1829 LENELNTK_______
5485 : Phospho-Afadin (Ser1718) Antibody
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