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Nkx2-3 (human)

Overview Nkx2-3 Transcription factor. Belongs to the NK-2 homeobox family. Note: This description may include information from UniProtKB. Protein type: DNA binding protein Cellular Component: nucleus Molecular Function: sequence-specific DNA binding; transcription factor activity Biological Process: spleen development; Peyer's patch development; plasma cell differentiation; macrophage differentiation; CD4-positive, alpha beta T cell differentiation; transcription, DNA-dependent; lymph node development; post-embryonic gut morphogenesis; regulation of cell proliferation; odontogenesis of dentine-containing teeth; triacylglycerol metabolic process; positive regulation of transcription from RNA polymerase II promoter; gland morphogenesis; leukocyte migration; leukocyte homeostasis Reference #:  Q8TAU0 (UniProtKB) Alt. Names/Synonyms: CSX3; Homeobox protein NK-2 homolog C; Homeobox protein Nkx-2.3; NK2 transcription factor related, locus 3 (Drosophila); NK2.3; NKX2-3; NKX2.3; NKX23; NKX2C; NKX4-3 Gene Symbols: NKX2-3 Molecular weight: 38,406 Da Basal Isoelectric point: 7.19  Predict pI for various phosphorylation states

Select Structure to View Below Nkx2-3

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	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		S211	KRQRQDKSLELGAHA
0	1		A216	DKSLELGAHAPPPPP
0	1		-	gap
0	1		-	gap

	mouse ► Hide Isoforms
S208-p	KRQRQDKsLELGtHA
T213-p	DKsLELGtHAPPPPP
-	gap
-	gap

	Nkx2-3 iso2
S208	KRQRQDKSLELGTHA
T213	DKSLELGTHAPPPPP
T376-p	TRRASYCtLGtAGMR
T379-p	ASYCtLGtAGMRHEK

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