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Protein Page:
Gsc2 (human)

Overview
Gsc2 May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC. Belongs to the paired homeobox family. Bicoid subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA binding protein
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: nucleus
Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; anatomical structure morphogenesis
Reference #:  O15499 (UniProtKB)
Alt. Names/Synonyms: goosecoid homeobox 2; goosecoid-like; GSC-2; GSC-L; GSC2; GSCL; Homeobox protein goosecoid-2; Homeobox protein goosecoid-like
Gene Symbols: GSC2
Molecular weight: 21,545 Da
Basal Isoelectric point: 10.58  Predict pI for various phosphorylation states
Select Structure to View Below

Gsc2

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 L102 RLGPAVPLSLGAPAG
0 1 G105 PAVPLSLGAPAGGSG
0 1 S122-p PGAVGPGsQRRTRRH
0 1 S154-p QNQYPDVstRERLAG
0 1 T155-p NQYPDVstRERLAGR
0 1 S190-p HQKRASAsARLLPGV
  mouse

 
S99-p RLAPATPsPLtAPRA
T102-p PATPsPLtAPRAGSP
P119 TGTSGPGPQRRTRRH
G151 QNQYPDVGTRERLAV
T152 NQYPDVGTRERLAVR
S187 HQKRASSSRLLPGTK
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