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Protein Page:
IL28A (human)

Overview
IL28A Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Secreted, signal peptide; Secreted
Cellular Component: extracellular space
Molecular Function: cytokine activity
Biological Process: defense response to virus
Reference #:  Q8IZJ0 (UniProtKB)
Alt. Names/Synonyms: Cytokine Zcyto20; IFN-lambda-2; IFNL2; IL-28A; IL28A; interferon lambda 2; Interferon lambda-2; interferon-lambda 2; interleukin 28A (interferon, lambda 2); Interleukin-28A; ZCYTO20
Gene Symbols: IFNL2
Molecular weight: 22,288 Da
Basal Isoelectric point: 8.15  Predict pI for various phosphorylation states
Select Structure to View Below

IL28A

Protein Structure Not Found.


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