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Protein Page:
NOXIN (mouse)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
NOXIN Acts as an anti-apoptotic factor and its absence increases cell death under normal and stress conditions. Can induce cell cycle arrest in the G1 or early S phase and this activity is independent of p53/TP53. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Cellular Component: cytoplasm; nucleus
Biological Process: apoptosis; hemopoiesis; cell cycle; cell cycle arrest; response to DNA damage stimulus; spermatid development
Reference #:  Q6NZG4 (UniProtKB)
Alt. Names/Synonyms: 4632434I11Rik; Nitric oxide-inducible gene protein; Noxin; RIKEN cDNA 4632434I11 gene
Gene Symbols: Noxin
Molecular weight: 99,945 Da
Basal Isoelectric point: 7.46  Predict pI for various phosphorylation states
Select Structure to View Below

NOXIN

Protein Structure Not Found.


STRING  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

 
0 1 S11 RRKFLFASVLAVQNS
0 2 Y22 VQNSNFIYPSCQRCF
0 1 S24 NSNFIYPSCQRCFSK
0 1 F39 IILESKRFTCPKCGS
0 1 S46 FTCPKCGSSGDTGST
0 1 S47 TCPKCGSSGDTGSTN
0 1 Y57-p TGSTNYRyKLSLKVA
0 1 S494 SNCKSNSSPHIQKES
0 1 H496 CKSNSSPHIQKESKA
0 1 S501 SPHIQKESKADKTEA
0 1 R516-m1 AVSIAGSrSDISEDF
0 1 T534 TCSSALFTSSKDREA
0 1 S535 CSSALFTSSKDREAF
0 1 S536 SSALFTSSKDREAFI
0 1 N623 WPKKEDDNFTICRKL
0 1 K793-ac NANYKNRkNSPLTGQ
0 1 - gap
0 3 - gap
  human

 
S11-p RRKFLLAsVLALQNS
Y22-p LQNSSFIyPsCQKCF
S24-p NSSFIyPsCQKCFSR
S39-p IILVSKRsNCPKCGs
S46-p sNCPKCGstGESGNA
T47-p NCPKCGstGESGNAN
Y57 SGNANYRYKLSLKVA
S504-p FNCKGNLsPsVEKEs
S506-p CKGNLsPsVEKEsQP
S511-p sPsVEKEsQPDNKVE
G526 AVSVNHNGRDMSEYF
S544-p PYLSALSsssKDLET
S545-p YLSALSsssKDLETI
S546-p LSALSsssKDLETIV
S624-p WSKNQDDsFTICRKL
R809 DGNYEKIRIFPENDK
K918-ac GTNKGLIkKKLKNML
K931-m3 MLAAVVTkKKTHKYN
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