May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA binding protein; C2H2-type zinc finger protein
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; DNA binding; metal ion binding; transcription factor activity
Biological Process: release of cytoplasmic sequestered NF-kappaB; regulation of protein heterodimerization activity; transcription, DNA-dependent; positive regulation of apoptosis; regulation of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein amino acid phosphorylation; positive regulation of cell differentiation; cell differentiation; positive regulation of transcription from RNA polymerase II promoter, mitotic; positive regulation of cell migration; negative regulation of apoptosis
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.