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Protein Page:
MRS2 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
MRS2 Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial
Chromosomal Location of Human Ortholog: 6p22.3-p22.1
Cellular Component: mitochondrial inner membrane; integral to membrane
Molecular Function: magnesium ion transmembrane transporter activity
Biological Process: magnesium ion transport
Reference #:  Q9HD23 (UniProtKB)
Alt. Names/Synonyms: HPT; Magnesium transporter MRS2 homolog, mitochondrial; MGC78523; MRS2; MRS2 magnesium homeostasis factor homolog (S. cerevisiae); MRS2-like protein; MRS2-like, magnesium homeostasis factor; MRS2L
Gene Symbols: MRS2
Molecular weight: 50,318 Da
Basal Isoelectric point: 6.44  Predict pI for various phosphorylation states
Select Structure to View Below

MRS2

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 - gap
0 2 K90-ac APVFTVTkFDKQGNV
0 1 K281-ub SDPQVFEkSSAGIDH
  mouse

 
R38-m1 CRTGVLGrLPGCPRA
K126-ac AQVFAVTkFDKEGNV
K317 SDPHVFEKSSTGIDH
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