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Protein Page:
TUBB8 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
TUBB8 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal protein
Cellular Component: microtubule; cytoplasm
Molecular Function: GTPase activity; GTP binding; structural constituent of cytoskeleton
Biological Process: protein polymerization; GTP catabolic process; microtubule-based process
Reference #:  Q3ZCM7 (UniProtKB)
Alt. Names/Synonyms: FLJ40100; HSA10p15 beta-tubulin 4Q; TBB8; TUBB8; Tubulin beta-8 chain; tubulin, beta 8
Gene Symbols: TUBB8
Molecular weight: 49,776 Da
Basal Isoelectric point: 4.79  Predict pI for various phosphorylation states
Select Structure to View Below

TUBB8

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T7-p _MREIVLtQIGQCGN
0 5 K122-ub SVMDVVRkEAEsCDC
0 1 S126-p VVRkEAEsCDCLQGF
0 7 K154-ub MGTLLLSkIREEyPD
0 1 Y159-p LSkIREEyPDRIINT
0 1 S168-p DRIINTFsILPsPKV
0 1 S172-p NTFsILPsPKVSDTV
0 1 K216-ub DICSKTLkLPTPTYG
0 73 K252-ub QLNADLRkLAVNMVP
0 19 Y281-p TSRGSQQyRALTVAE
0 1 K297-ub TQQMFDAkNMMAACD
0 4 S339-p NIQDKNSsyFADWLP
0 3 Y340-p IQDKNSsyFADWLPN
0 2 R380-m1 AIQELFKrVSEQFTA
0 3 K392-ub FTAMFRRkAFLHWYT
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