Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Belongs to the protamine P1 family. Note: This description may include information from UniProtKB.
Protein type: DNA binding protein; Cancer Testis Antigen (CTA)
Cellular Component: nucleoplasm; nucleosome
Molecular Function: DNA binding
Biological Process: chromosome condensation; multicellular organismal development; spermatogenesis; DNA packaging; spermatid development; nuclear organization and biogenesis
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.