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Protein Page:
LHX6 (human)

Overview
LHX6 Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA binding protein
Cellular Component: nucleus
Molecular Function: zinc ion binding; sequence-specific DNA binding; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; cerebral cortex GABAergic interneuron migration; cerebral cortex tangential migration; cell maturation; cerebral cortex radially oriented cell migration; forebrain neuron fate commitment
Reference #:  Q9UPM6 (UniProtKB)
Alt. Names/Synonyms: LHX6; LHX6.1; LIM homeobox 6; LIM homeobox protein 6; LIM homeodomain protein 6.1; LIM/homeobox protein Lhx6; LIM/homeobox protein Lhx6.1; MGC119542; MGC119544; MGC119545
Gene Symbols: LHX6
Molecular weight: 40,045 Da
Basal Isoelectric point: 8.77  Predict pI for various phosphorylation states
Select Structure to View Below

LHX6

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 2 Y185-p KVLCRIHyDtMIENL
0 1 T187-p LCRIHyDtMIENLKR
  mouse

 
Y185 KVLCRIHYDTMIENL
T187 LCRIHYDTMIENLKR
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