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Protein Page:
GPS2 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
GPS2 Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; G protein regulator, misc.; Cell cycle regulation; Inhibitor protein; Transcription, coactivator/corepressor
Cellular Component: transcriptional repressor complex; nucleus
Molecular Function: protein binding; transcription corepressor activity; GTPase inhibitor activity
Biological Process: negative regulation of JNK cascade; JNK cascade; negative regulation of transcription from RNA polymerase II promoter; cell cycle; inactivation of MAPK activity
Reference #:  Q13227 (UniProtKB)
Alt. Names/Synonyms: AMF-1; G protein pathway suppressor 2; GPS-2; GPS2; MGC104294; MGC119287; MGC119288; MGC119289
Gene Symbols: GPS2
Molecular weight: 36,689 Da
Basal Isoelectric point: 9.52  Predict pI for various phosphorylation states
CST Pathways:  Protein Acetylation
Select Structure to View Below

GPS2

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K66-ub RMSLEETkEQILKLE
0 4 R312-m2 ATSQPGPrLPFIQHS
1 0 R323-m1 IQHSQNPrFYHK___
1 3 R323-m2 IQHSQNPrFYHK___
  mouse

 
K66 RMSLEETKEQILKLQ
R312-m2 TTSQPGPrLPFIQHS
R323 IQHSQNPRFYHK___
R323-m2 IQHSQNPrFYHK___
  rat

 
K66 RMSLEETKEQILKLQ
R312 TTSQPGPRLPFIQHS
R323 IQHSQNPRFYHK___
R323 IQHSQNPRFYHK___
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