synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The replication of DNA is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Note: This description may include information from UniProtKB.
Cellular Component: nucleoplasm; alpha DNA polymerase:primase complex
Molecular Function: DNA primase activity; DNA binding; metal ion binding; 4 iron, 4 sulfur cluster binding
Biological Process: telomere maintenance via semi-conservative replication; DNA replication initiation; M/G1 transition of mitotic cell cycle; telomere maintenance via recombination; DNA replication, synthesis of RNA primer; mitotic cell cycle; DNA strand elongation during DNA replication; S phase of mitotic cell cycle; telomere maintenance; G1/S transition of mitotic cell cycle
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.