a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes. Does not associate with DNA or RelA/NFkB-p65. Note: This description may include information from UniProtKB.
Biological Process: transcription from RNA polymerase II promoter; I-kappaB kinase/NF-kappaB cascade; antigen processing and presentation; response to cytokine stimulus; T-helper 1 cell differentiation; innate immune response; positive regulation of transcription from RNA polymerase II promoter; myeloid dendritic cell differentiation; circadian regulation of gene expression; negative regulation of transcription from RNA polymerase II promoter; inflammatory response
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.