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Protein Page:
GPR18 (human)

Overview
GPR18 Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 13q32
Cellular Component: plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Reference #:  Q14330 (UniProtKB)
Alt. Names/Synonyms: G protein-coupled receptor 18; G-protein coupled receptor 18; GPCRW; GPR18; N-arachidonyl glycine receptor; NAGly receptor
Gene Symbols: GPR18
Molecular weight: 38,134 Da
Basal Isoelectric point: 9.38  Predict pI for various phosphorylation states
Select Structure to View Below

GPR18

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T3-p _____MItLNNQDQP
0 1 Y303-p RVISVMLyRNYLRSM
0 2 S317 MRRKSFRSGSLRSLS
0 1 S319 RKSFRSGSLRSLSNI
0 5 S322 FRSGSLRSLSNINSE
  mouse

 
T3 _____MATLSNHNQL
Y303 RVISVMLYRNYLRSV
S317-p VRRKSVRsGsLRsLS
S319-p RKSVRsGsLRsLSNM
S322-p VRsGsLRsLSNMNSE
  rat

 
I3 _____MAIPSNRDQL
Y303 RVISVMLYRNYLRSV
S317 VRRKSVRSGSLRsLS
S319 RKSVRSGSLRsLSNM
S322-p VRSGSLRsLSNMNSE
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