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Protein Page:
RAD21L1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
RAD21L1 Meiosis-specific component of some cohesin complex. Probably required during early meiosis for separation of sister chromatids and homologous chromosomes. Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I. May be involved in synapsis initiation and crossover recombination between homologous chromosomes. Belongs to the rad21 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Cellular Component: lateral element; chromosome; nucleus
Biological Process: fertilization; linear element formation; spermatogenesis; meiotic prophase I; double-strand break repair via homologous recombination; chromosome segregation
Reference #:  Q9H4I0 (UniProtKB)
Alt. Names/Synonyms: Double-strand-break repair protein rad21-like protein 1; RAD21L1; RD21L
Gene Symbols: RAD21L1
Molecular weight: 63,324 Da
Basal Isoelectric point: 5.07  Predict pI for various phosphorylation states
Select Structure to View Below

RAD21L1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T429-p QHSSHEDtNKNINSE
0 10 K521-ub DRKQAAAkFYSFLVL
0 1 N555 TMGPMFYNI______
  mouse

 
V427 VGSFQENVNMNVNSE
K517 DRKQAAAKFYTLLIL
K551-ub TVGPMFYkM______
  rat

 
I428 MGSFQENINRNINSK
K518 DRKQAAAKFYTLLIL
K552 TVGPMFHKL______
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