|
MyoD
a transcription factor of the basic helix-loop-helix family and the myogenic factors subfamily. Involved in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. It is involved in muscle cell differentiation, and is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis. Note: This description may include information from UniProtKB.
|
| Protein type: DNA binding protein; Transcription factor; RNA splicing |
|
Cellular Component: nucleoplasm; transcription factor complex; myofibril; nuclear chromatin; nucleus
|
|
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein heterodimerization activity; ubiquitin protein ligase binding; transcription coactivator activity; transcription factor binding
|
|
Biological Process: muscle development; skeletal muscle development; skeletal muscle fiber adaptation; positive regulation of skeletal muscle regeneration; myotube differentiation involved in skeletal muscle regeneration; muscle cell fate commitment; skeletal muscle fiber development; cellular response to starvation; protein amino acid phosphorylation; cardiac muscle cell differentiation; regulation of transcription from RNA polymerase II promoter; muscle cell differentiation; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; myoblast cell fate determination; regulation of alternative nuclear mRNA splicing, via spliceosome
|
|
Reference #:
P15172 (UniProtKB)
|
| Alt. Names/Synonyms: BHLHC1; Class C basic helix-loop-helix protein 1; Myf-3; MYF3; Myoblast determination protein 1; MYOD; MYOD1; myogenic differentiation 1; Myogenic factor 3; PUM |
| Gene Symbols: MYOD1 |
|
Molecular weight: 34,501 Da
|
|
Basal Isoelectric point: 5.56
Predict pI for various phosphorylation states
|
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
|
