a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; Adaptor/scaffold
Molecular Function: insulin-like growth factor receptor binding; protein domain specific binding; protein binding; enzyme binding; sodium channel regulator activity; protein heterodimerization activity; actin binding; glucocorticoid receptor binding
Biological Process: transcription initiation from RNA polymerase II promoter; apoptosis; regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; programmed cell death; regulation of synaptic plasticity; negative regulation of dendrite morphogenesis; regulation of sodium ion transport; intracellular protein transport; substantia nigra development; small GTPase mediated signal transduction; glucocorticoid receptor signaling pathway; glucocorticoid catabolic process; gene expression
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.