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Protein Page:
TNNC2 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
TNNC2 Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Belongs to the troponin C family. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis
Cellular Component: troponin complex; cytosol
Molecular Function: calcium ion binding; actin binding
Biological Process: skeletal muscle contraction; regulation of muscle contraction; muscle filament sliding
Reference #:  P02585 (UniProtKB)
Alt. Names/Synonyms: TNNC2; troponin C type 2 (fast); Troponin C, skeletal muscle; troponin C2, fast
Gene Symbols: TNNC2
Molecular weight: 18,122 Da
Basal Isoelectric point: 4.06  Predict pI for various phosphorylation states
Select Structure to View Below

TNNC2
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 2 K89 RQMKEDAKGKSEEEL
0 3 K38 GGGDISVKELGtVMR
0 2 K91 MKEDAKGKSEEELAE
0 1 K137 EEIESLMKDGDKNND
0 2 K141 SLMKDGDKNNDGRID
  mouse

 
K89-u RQMKEDAkGkSEEEL
K38-u GGGDISVkELGTVMR
K91-u MKEDAkGkSEEELAE
K137-u EEIESLMkDGDkNND
K141-u SLMkDGDkNNDGRID
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