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Protein Page:
plectin 1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
plectin 1 a major cytoskeleton crosslinking protein that binds to actin, intermediate filaments and microtubules. A scaffold for proteins involved in cellular signaling. Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics. Regulates the organization of keratin intermediate filaments (IF) and MAPK signaling during cell migration. Downregulates PKC signaling by sequestering RACK1. Redistributes to the uropod associated with vimentin and fodrin during polarization of peripheral blood T lymphocytes. This vimentin-plectin-fodrin complex provides a continuous linkage from the nucleus (lamin B) to the cortical cytoskeleton. Defects in PLEC1 are the cause of epidermolysis bullosa simplex 1 (EBS1). Three alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal protein
Cellular Component: intermediate filament cytoskeleton; costamere; focal adhesion; hemidesmosome; cytoplasm; plasma membrane; cytosol; sarcoplasm; sarcolemma
Molecular Function: protein binding; structural constituent of muscle; ankyrin binding; actin binding
Biological Process: hemidesmosome assembly; apoptosis; cell structure disassembly during apoptosis
Reference #:  Q15149 (UniProtKB)
Alt. Names/Synonyms: EBS1; EBSO; HD1; Hemidesmosomal protein 1; PCN; PLEC; PLEC1; PLEC1b; plectin; plectin 1, intermediate filament binding protein 500kDa; Plectin-1; PLTN
Gene Symbols: PLEC
Molecular weight: 531,791 Da
Basal Isoelectric point: 5.74  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

plectin 1
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

► Hide Isoforms 		 
0 1 S54 QVMRAMASLRARGLV
0 3 T113-p MVMPARRtPHVQAVQ
0 6 S125-p AVQGPLGsPPkRGPL
0 3 K128-u GPLGsPPkRGPLPTE
0 1 K143-u EQRVYRRkELEEVsP
0 4 S149-p RkELEEVsPETPVVP
0 2 - gap
0 16 - gap
0 5 - gap
0 1 - gap
0 1 - gap
0 9 - gap
0 66 - gap
0 74 - gap
0 185 - gap
0 51 - gap
0 1 - gap
0 1 K187-a VQKKTFTkWVNKHLI
0 1 S201-p IKAQRHIsDLYEDLR
0 1 S284-p IILHFQIsDIQVSGQ
0 1 S305-p KEKLLLWsQRMVEGY
0 1 T351-p MNKVYRQtNLENLDQ
0 1 S361-p ENLDQAFsVAERDLG
0 1 S394 SIITYVSSLyDAMPR
0 33 Y396-p ITYVSSLyDAMPRVP
0 1 K462-a WSQFLKFkEMELPAk
0 1 K469-u kEMELPAkEADKNRS
0 1 K477-u EADKNRSkGIyQSLE
0 7 Y480-p KNRSkGIyQSLEGAV
0 1 K493-u AVQAGQLkVPPGYHP
0 1 K581-u EVERDLDkADSMIRL
0 1 K597-u FNDVQTLkDGRHPQG
0 2 Y608-p HPQGEQMyRRVyRLH
0 1 Y612-p EQMyRRVyRLHERLV
0 1 K630-u TEYNLRLkAGVAAPA
0 1 T638 AGVAAPATQVAQVTL
0 25 S720-p RSDEGQLsPATRGAY
0 1 T723 EGQLsPATRGAYRDC
0 1 K740-u RLDLQYAkLLNSSKA
0 1 S782-p EEVGFDWsDRNTNMT
0 1 S796-p TAKKESYsALMRELE
0 1 A815 KIKELQNAGDRLLRE
0 1 Y861-p HLKENAAyFQFFSDV
0 14 S887-p EALRRKYsCDRsATV
0 2 S891-p RKYsCDRsATVTRLE
0 2 K908-a LQDAQDEkEQLNEyK
0 1 K908-u LQDAQDEkEQLNEyK
0 1 Y914-p EkEQLNEyKGHLsGL
0 1 K915 kEQLNEyKGHLsGLA
0 1 S919-p NEyKGHLsGLAKRAK
0 3 K953-a LLAVCDYkQVEVTVH
0 6 S1047-p VQLIRSWsLATFRTL
0 2 Y1095 RLMAEREYGSCSHHY
0 4 K1165-u QRIAEQQkAQAEVEG
0 2 K1175-u AEVEGLGkGVARLSA
0 2 K1186-u RLSAEAEkVLALPEP
0 50 K1210-u ELELTLGkLEQVRSL
0 1 G1234 TISLVIRGTQGAEEV
0 1 T1235 ISLVIRGTQGAEEVL
0 1 K1250-u RAHEEQLkEAQAVPA
0 1 K1410-u EECQRFAkQYINAIk
0 1 K1417-u kQYINAIkDYELQLV
0 1 Y1426-p YELQLVTykAQLEPV
0 1 K1427-u ELQLVTykAQLEPVA
0 30 S1435-p AQLEPVAsPAKKPKV
0 1 T1465 THYSELTTLTSQYIK
0 1 Y1470 LTTLTSQYIKFISET
0 2 K1508-u EVEAALEkQRQLAEA
0 1 S1565-p ELQQLRQsSEAEIQA
0 1 K1573 SEAEIQAKARQAEAA
0 1 R1627-m1 EEAEAQKrQAQEEAE
0 1 R1637-m1 QEEAERLrRQVQDEs
0 1 S1644-p rRQVQDEsQRKRQAE
0 2 K1718-u AEAELQSkRAsFAEK
0 12 S1721-p ELQSkRAsFAEKTAQ
0 9 S1732-p KTAQLERsLQEEHVA
0 1 R1812-m1 EAEREARrRGKAEEQ
0 1 S1907-p EMEVLLAskARAEEE
0 1 K1908-a MEVLLAskARAEEES
0 1 T1983-p LAAIGEAtRLKTEAE
0 1 T2053-p QKGLVEDtLRQRRQV
0 1 K2182-a LAQEAAQkRLQAEEk
0 1 K2189-a kRLQAEEkAHAFAVQ
0 1 K2255-a VEEAERLkQSAEEQA
0 1 K2274-a QAQAAAEkLRKEAEQ
0 1 K2350-u DEELQRLkAEAtEAA
0 1 T2354-p QRLkAEAtEAARQRs
0 2 S2361-p tEAARQRsQVEEELF
0 1 S2516-p RQRQLEMsAEAERLK
0 3 S2578-p LEIQRQQsDHDAERL
0 1 K2604-u EKLQQEAkLLQLKSE
0 1 T2615-p LKSEEMQtVQQEQLL
0 1 K2636 QQSFLSEKDSLLQRE
0 1 K2650-u ERFIEQEkAKLEQLF
0 1 K2663-u LFQDEVAkAQQLREE
0 2 S2688-p ERQRLVAsMEEARRR
0 3 S2755-p HSEEVTAsQVAATKT
0 1 A2774 RDALDGPAAEAEPEH
0 5 S2791-p DGLRRKVsAQRLQEA
0 2 S2802-p LQEAGILsAEELQRL
0 10 R2826 LARREDVRHYLQGRS
0 1 K2841-a SIAGLLLkATNEKLS
0 1 K2841-u SIAGLLLkATNEKLS
0 41 T2886-p PVRNRRLtVNEAVKE
0 3 K2915-u ERAVTGYkDPYTGQQ
0 1 T2949-p LLEAQIAtGGVIDPV
0 2 K2988-u ADPSDDTkGFFDPNT
0 1 K3027-u PLTDKAAkGGELVyT
0 12 Y3033-p AkGGELVyTDSEARD
0 1 K3053 TVSAPFGKFQGKTVT
0 1 K3091-a TGRITVEkIIKIIIT
0 38 Y3134-p RVIDRELyQQLQRGE
0 5 T3152-p RDVAEVDtVRRALRG
0 1 Y3178 AGQKLSIYNALKKDL
0 1 S3188-p LKKDLLPsDMAVALL
0 1 K3237 EKLLSAEKAVTGYRD
0 1 Y3246 VTGYRDPYTGQSVsL
0 1 S3252-p PYTGQSVsLFQALKK
0 1 S3276-p RLLDAQLstGGIVDP
0 1 T3277-p LLDAQLstGGIVDPs
0 1 S3284-p tGGIVDPsKSHRVPL
0 1 E3302 CARGCLDEETSRALS
0 1 K3316-u SAPRADAkAYSDPST
0 13 Y3329-p STGEPATyGELQQRC
0 1 K3352 SLLPLSEKAARARQE
0 134 Y3362-p RARQEELySELQARE
0 1 P3375 RETFEKTPVEVPVGG
0 3 K3384-u EVPVGGFkGRTVTVW
0 1 Y3398-p WELISSEyFtAEQRQ
0 1 T3400-p LISSEyFtAEQRQEL
0 1 K3420-a TGKVTVEkVIKILIT
0 1 T3427 kVIKILITIVEEVET
0 1 S3457-p PASELLAsGVLsRAQ
0 1 G3458 ASELLAsGVLsRAQF
0 1 S3461-p LLAsGVLsRAQFEQL
0 1 T3486-p SELGSVRtLLQGsGC
0 1 S3491-p VRtLLQGsGCLAGIy
0 3 Y3498-p sGCLAGIyLEDTkEK
0 3 K3503-a GIyLEDTkEKVSIyE
0 1 Y3509-p TkEKVSIyEAMRrGL
0 1 R3514-m1 SIyEAMRrGLLRATT
0 1 K3590-u SLFQAMQkGLVLRQH
0 1 K3647-u ADPSDDTkGFFDPNT
0 1 T3766-p IIEIIEKtEIIRQQG
0 2 S3776-p IRQQGLAsyDyVRRR
0 41 Y3777-p RQQGLAsyDyVRRRL
0 2 Y3779-p QGLAsyDyVRRRLtA
0 7 T3785-p DyVRRRLtAEDLFEA
0 8 F3790 RLtAEDLFEARIISL
0 1 T3799-p ARIISLEtYNLLREG
0 1 T3807-p YNLLREGtRSLREAL
0 16 Y3833 TGSVAGVYLPGSRQT
0 1 Y3844-p SRQTLSIyQALKKGL
0 1 T3930-p MKKELIPtEEALRLL
0 1 K3968-u YQRGYLNkDTHDQLS
0 1 T4007-p RCRRDDGtGQLLLPL
0 4 T4021-p LSDARKLtFRGLRkQ
0 1 K4027-u LtFRGLRkQItMEEL
0 55 T4030-p RGLRkQItMEELVRs
0 1 S4037-p tMEELVRsQVMDEAT
0 1 S4054-p QLREGLTsIEEVTkN
0 1 K4060-u TsIEEVTkNLQKFLE
0 1 K4081-u GVFVDATkERLSVYQ
0 1 K4121-u IDPIKGLkLTVEEAV
0 1 K4138-u GIVGPEFkDKLLSAE
0 1 K4152-u ERAVTGYkDPySGkL
0 52 Y4155-p VTGYkDPySGkLISL
0 1 K4158-u YkDPySGkLISLFQA
0 1 K4167-a ISLFQAMkKGLILKD
0 7 K4205-a LPVEVAYkRGLFDEE
0 1 K4205-u LPVEVAYkRGLFDEE
0 23 T4267-p EKKRERKtssKssVR
0 127 S4268-p KKRERKtssKssVRK
0 5 S4269-p KRERKtssKssVRKR
0 1 S4271-p ERKtssKssVRKRRV
0 8 S4272-p RKtssKssVRKRRVV
0 1 T4285-p VVIVDPEtGkEMSVY
0 1 K4287-u IVDPEtGkEMSVYEA
0 1 R4296 MSVYEAYRKGLIDHQ
0 1 S4329-p SSDGVVKsMIIDRRs
0 1 S4336-p sMIIDRRsGRQyDID
0 1 Y4340-p DRRsGRQyDIDDAIA
0 1 K4348-u DIDDAIAkNLIDRsA
0 2 S4354-p AkNLIDRsALDQYRA
0 3 T4367-p RAGTLSItEFADMLs
0 2 S4374-p tEFADMLsGNAGGFR
0 52 S4382-p GNAGGFRsRsssVGs
0 79 S4384-p AGGFRsRsssVGsss
0 77 S4385-p GGFRsRsssVGssss
0 281 S4386-p GFRsRsssVGssssy
0 127 S4389-p sRsssVGssssyPIs
0 44 S4390-p RsssVGssssyPIsP
0 12 S4391-p sssVGssssyPIsPA
0 11 S4392-p ssVGssssyPIsPAV
0 28 Y4393-p sVGssssyPIsPAVs
0 178 S4396-p ssssyPIsPAVsRtQ
0 1 P4397 sssyPIsPAVsRtQL
0 8 S4400-p yPIsPAVsRtQLAsW
0 3 T4402-p IsPAVsRtQLAsWsD
0 10 S4406-p VsRtQLAsWsDPTEE
0 3 S4408-p RtQLAsWsDPTEETG
0 1 K4480 VNKGLVDKIMVDRIN
0 1 K4491-a DRINLAQkAFCGFED
0 1 T4501-p CGFEDPRtKTKMSAA
0 1 K4513-u SAAQALKkGWLyyEA
0 2 Y4517-p ALKkGWLyyEAGQRF
0 1 Y4518-p LKkGWLyyEAGQRFL
1 1 T4539-p GGLIEPDtPGRVPLD
0 2 G4566 AQKLRDVGAYSKYLT
0 2 K4609-u EAAAQSTkGyysPys
0 146 Y4611-p AAQSTkGyysPysVs
0 20 Y4612-p AQSTkGyysPysVsG
0 140 S4613-p QSTkGyysPysVsGs
0 289 Y4615-p TkGyysPysVsGsGs
0 34 S4616-p kGyysPysVsGsGst
0 33 S4618-p yysPysVsGsGstAG
0 26 S4620-p sPysVsGsGstAGsR
0 77 S4622-p ysVsGsGstAGsRtG
0 30 T4623-p sVsGsGstAGsRtGs
0 70 S4626-p GsGstAGsRtGsrtG
0 19 T4628-p GstAGsRtGsrtGsR
0 14 S4630-p tAGsRtGsrtGsRAG
0 1 R4631-m2 AGsRtGsrtGsRAGs
0 3 T4632-p GsRtGsrtGsRAGsR
0 7 S4634-p RtGsrtGsRAGsRRG
0 2 S4638-p rtGsRAGsRRGsFDA
0 109 S4642-p RAGsRRGsFDAtGsG
0 6 T4646-p RRGsFDAtGsGFSMT
0 7 S4648-p GsFDAtGsGFSMTFS
0 1 T4653 tGsGFSMTFSsSSys
0 1 S4656-p GFSMTFSsSSysSSG
0 3 Y4659-p MTFSsSSysSSGyGR
0 1 S4660-p TFSsSSysSSGyGRR
0 1 Y4664-p SSysSSGyGRRYAsG
0 3 S4670-p GyGRRYAsGsSAsLG
0 6 S4672-p GRRYAsGsSAsLGGP
0 2 S4675-p YAsGsSAsLGGPESA
  plectin 1 iso2  
- gap
- gap
- gap
- gap
- gap
- gap
S22-p VSNGSSGsPSPGDtL
T28-p GsPSPGDtLPWNLGK
S42-p KTQRSRRsGGGAGSN
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
K77 VQKKTFTKWVNKHLI
S91 IKAQRHISDLYEDLR
S174 IILHFQISDIQVSGQ
S195 KEKLLLWSQRMVEGY
T241 MNKVYRQTNLENLDQ
S251 ENLDQAFSVAERDLG
S284 SIITYVSSLYDAMPR
Y286 ITYVSSLYDAMPRVP
K352 WSQFLKFKEMELPAK
K359 KEMELPAKEADKNRS
K367 EADKNRSKGIYQSLE
Y370 KNRSKGIYQSLEGAV
K383 AVQAGQLKVPPGYHP
K471 EVERDLDKADSMIRL
K487 FNDVQTLKDGRHPQG
Y498 HPQGEQMYRRVYRLH
Y502 EQMYRRVYRLHERLV
K520 TEYNLRLKAGVAAPA
T528 AGVAAPATQVAQVTL
S610 RSDEGQLSPATRGAY
T613 EGQLSPATRGAYRDC
K630 RLDLQYAKLLNSSKA
S672 EEVGFDWSDRNTNMT
S686 TAKKESYSALMRELE
A705 KIKELQNAGDRLLRE
Y751 HLKENAAYFQFFSDV
S777 EALRRKYSCDRSATV
S781 RKYSCDRSATVTRLE
K798 LQDAQDEKEQLNEYK
K798 LQDAQDEKEQLNEYK
Y804 EKEQLNEYKGHLSGL
K805 KEQLNEYKGHLSGLA
S809 NEYKGHLSGLAKRAK
K843 LLAVCDYKQVEVTVH
S937 VQLIRSWSLATFRTL
Y985 RLMAEREYGSCSHHY
K1055 QRIAEQQKAQAEVEG
K1065 AEVEGLGKGVARLSA
K1076 RLSAEAEKVLALPEP
K1100 ELELTLGKLEQVRSL
G1124 TISLVIRGTQGAEEV
T1125 ISLVIRGTQGAEEVL
K1140 RAHEEQLKEAQAVPA
K1300 EECQRFAKQYINAIK
K1307 KQYINAIKDYELQLV
Y1316 YELQLVTYKAQLEPV
K1317 ELQLVTYKAQLEPVA
S1325 AQLEPVASPAKKPKV
T1355 THYSELTTLTSQYIK
Y1360 LTTLTSQYIKFISET
K1398 EVEAALEKQRQLAEA
S1455 ELQQLRQSSEAEIQA
K1463 SEAEIQAKARQAEAA
R1517 EEAEAQKRQAQEEAE
R1527 QEEAERLRRQVQDES
S1534 RRQVQDESQRKRQAE
K1608 AEAELQSKRASFAEK
S1611 ELQSKRASFAEKTAQ
S1622 KTAQLERSLQEEHVA
R1702 EAEREARRRGKAEEQ
S1797 EMEVLLASKARAEEE
K1798 MEVLLASKARAEEES
T1873 LAAIGEATRLKTEAE
T1943 QKGLVEDTLRQRRQV
K2072 LAQEAAQKRLQAEEK
K2079 KRLQAEEKAHAFAVQ
K2145-a VEEAERLkQSAEEQA
K2164-a QAQAAAEkLRKEAEQ
K2240 DEELQRLKAEATEAA
T2244 QRLKAEATEAARQRS
S2251 TEAARQRSQVEEELF
S2406 RQRQLEMSAEAERLK
S2468 LEIQRQQSDHDAERL
K2494 EKLQQEAKLLQLKSE
T2505 LKSEEMQTVQQEQLL
K2526 QQSFLSEKDSLLQRE
K2540 ERFIEQEKAKLEQLF
K2553 LFQDEVAKAQQLREE
S2578 ERQRLVASMEEARRR
S2645 HSEEVTASQVAATKT
A2664 RDALDGPAAEAEPEH
S2681 DGLRRKVSAQRLQEA
S2692 LQEAGILSAEELQRL
R2716 LARREDVRHYLQGRS
K2731 SIAGLLLKATNEKLS
K2731 SIAGLLLKATNEKLS
T2776-p PVRNRRLtVNEAVKE
K2805 ERAVTGYKDPYTGQQ
T2839 LLEAQIATGGVIDPV
K2878 ADPSDDTKGFFDPNT
K2917 PLTDKAAKGGELVYT
Y2923 AKGGELVYTDSEARD
K2943 TVSAPFGKFQGKTVT
K2981 TGRITVEKIIKIIIT
Y3024 RVIDRELYQQLQRGE
T3042 RDVAEVDTVRRALRG
Y3068 AGQKLSIYNALKKDL
S3078 LKKDLLPSDMAVALL
K3127 EKLLSAEKAVTGYRD
Y3136 VTGYRDPYTGQSVSL
S3142 PYTGQSVSLFQALKK
S3166 RLLDAQLSTGGIVDP
T3167 LLDAQLSTGGIVDPS
S3174 TGGIVDPSKSHRVPL
E3192 CARGCLDEETSRALS
K3206 SAPRADAKAYSDPST
Y3219 STGEPATYGELQQRC
K3242 SLLPLSEKAARARQE
Y3252 RARQEELYSELQARE
P3265 RETFEKTPVEVPVGG
K3274 EVPVGGFKGRTVTVW
Y3288 WELISSEYFTAEQRQ
T3290 LISSEYFTAEQRQEL
K3310 TGKVTVEKVIKILIT
T3317 KVIKILITIVEEVET
S3347 PASELLASGVLSRAQ
G3348 ASELLASGVLSRAQF
S3351 LLASGVLSRAQFEQL
T3376 SELGSVRTLLQGSGC
S3381 VRTLLQGSGCLAGIY
Y3388 SGCLAGIYLEDTKEK
K3393 GIYLEDTKEKVSIYE
Y3399 TKEKVSIYEAMRRGL
R3404 SIYEAMRRGLLRATT
K3480 SLFQAMQKGLVLRQH
K3537 ADPSDDTKGFFDPNT
T3656 IIEIIEKTEIIRQQG
S3666 IRQQGLASYDYVRRR
Y3667 RQQGLASYDYVRRRL
Y3669 QGLASYDYVRRRLTA
T3675 DYVRRRLTAEDLFEA
F3680 RLTAEDLFEARIISL
T3689 ARIISLETYNLLREG
T3697 YNLLREGTRSLREAL
Y3723 TGSVAGVYLPGSRQT
Y3734 SRQTLSIYQALKKGL
T3820 MKKELIPTEEALRLL
K3858 YQRGYLNKDTHDQLS
T3897 RCRRDDGTGQLLLPL
T3911 LSDARKLTFRGLRKQ
K3917 LTFRGLRKQITMEEL
T3920 RGLRKQITMEELVRS
S3927 TMEELVRSQVMDEAT
S3944 QLREGLTSIEEVTKN
K3950 TSIEEVTKNLQKFLE
K3971 GVFVDATKERLSVYQ
K4011 IDPIKGLKLTVEEAV
K4028 GIVGPEFKDKLLSAE
K4042 ERAVTGYKDPySGKL
Y4045-p VTGYKDPySGKLISL
K4048 YKDPySGKLISLFQA
K4057 ISLFQAMKKGLILKD
K4095 LPVEVAYKRGLFDEE
K4095 LPVEVAYKRGLFDEE
T4157-p EKKRERKtssKSsVR
S4158-p KKRERKtssKSsVRK
S4159-p KRERKtssKSsVRKR
S4161 ERKtssKSsVRKRRV
S4162-p RKtssKSsVRKRRVV
T4175 VVIVDPETGKEMSVY
K4177 IVDPETGKEMSVYEA
R4186 MSVYEAYRKGLIDHQ
S4219 SSDGVVKSMIIDRRS
S4226 SMIIDRRSGRQYDID
Y4230 DRRSGRQYDIDDAIA
K4238 DIDDAIAKNLIDRSA
S4244 AKNLIDRSALDQYRA
T4257 RAGTLSITEFADMLS
S4264 TEFADMLSGNAGGFR
S4272-p GNAGGFRsRsssVGs
S4274-p AGGFRsRsssVGsss
S4275-p GGFRsRsssVGssss
S4276-p GFRsRsssVGssssY
S4279-p sRsssVGssssYPIs
S4280-p RsssVGssssYPIsP
S4281-p sssVGssssYPIsPA
S4282-p ssVGssssYPIsPAV
Y4283 sVGssssYPIsPAVs
S4286-p ssssYPIsPAVsRTQ
P4287 sssYPIsPAVsRTQL
S4290-p YPIsPAVsRTQLASW
T4292 IsPAVsRTQLASWSD
S4296 VsRTQLASWSDPTEE
S4298 RTQLASWSDPTEETG
K4370 VNKGLVDKIMVDRIN
K4381 DRINLAQKAFCGFED
T4391 CGFEDPRTKTKMSAA
K4403 SAAQALKKGWLYYEA
Y4407 ALKKGWLYYEAGQRF
Y4408 LKKGWLYYEAGQRFL
T4429 GGLIEPDTPGRVPLD
G4456 AQKLRDVGAYSKYLT
K4499 EAAAQSTKGyySPyS
Y4501-p AAQSTKGyySPySVS
Y4502-p AQSTKGyySPySVSG
S4503 QSTKGyySPySVSGS
Y4505-p TKGyySPySVSGSGS
S4506 KGyySPySVSGSGST
S4508 yySPySVSGSGSTAG
S4510 SPySVSGSGSTAGSR
S4512 ySVSGSGSTAGSRTG
T4513 SVSGSGSTAGSRTGS
S4516 GSGSTAGSRTGSRTG
T4518 GSTAGSRTGSRTGSR
S4520 TAGSRTGSRTGSRAG
R4521 AGSRTGSRTGSRAGS
T4522 GSRTGSRTGSRAGSR
S4524 RTGSRTGSRAGSRRG
S4528 RTGSRAGSRRGsFDA
S4532-p RAGSRRGsFDATGSG
T4536 RRGsFDATGSGFSMT
S4538 GsFDATGSGFSMTFS
T4543 TGSGFSMTFSSSSYS
S4546 GFSMTFSSSSYSSSG
Y4549 MTFSSSSYSSSGYGR
S4550 TFSSSSYSSSGYGRR
Y4554 SSYSSSGYGRRYASG
S4560 GYGRRYASGSSASLG
S4562 GRRYASGSSASLGGP
S4565 YASGSSASLGGPESA
  plectin 1 iso4  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
T19-p EGLGRKRtssEDNLy
S20-p GLGRKRtssEDNLyL
S21-p LGRKRtssEDNLyLA
Y26-p tssEDNLyLAVLRAs
S33-p yLAVLRAsEGKKDER
K50 VQKKTFTKWVNKHLI
S64 IKAQRHISDLYEDLR
S147 IILHFQISDIQVSGQ
S168 KEKLLLWSQRMVEGY
T214 MNKVYRQTNLENLDQ
S224 ENLDQAFSVAERDLG
S257 SIITYVSSLYDAMPR
Y259 ITYVSSLYDAMPRVP
K325 WSQFLKFKEMELPAK
K332 KEMELPAKEADKNRS
K340 EADKNRSKGIyQSLE
Y343-p KNRSKGIyQSLEGAV
K356 AVQAGQLKVPPGYHP
K444 EVERDLDKADSMIRL
K460 FNDVQTLKDGRHPQG
Y471-p HPQGEQMyRRVyRLH
Y475-p EQMyRRVyRLHERLV
K493 TEYNLRLKAGVAAPA
T501 AGVAAPATQVAQVTL
S583 RSDEGQLSPATRGAY
T586 EGQLSPATRGAYRDC
K603 RLDLQYAKLLNSSKA
S645 EEVGFDWSDRNTNMT
S659 TAKKESYSALMRELE
A678 KIKELQNAGDRLLRE
Y724 HLKENAAYFQFFSDV
S750 EALRRKYSCDRSATV
S754 RKYSCDRSATVTRLE
K771 LQDAQDEKEQLNEYK
K771 LQDAQDEKEQLNEYK
Y777 EKEQLNEYKGHLSGL
K778 KEQLNEYKGHLSGLA
S782 NEYKGHLSGLAKRAK
K816 LLAVCDYKQVEVTVH
S910 VQLIRSWSLATFRTL
Y958 RLMAEREYGSCSHHY
K1028 QRIAEQQKAQAEVEG
K1038 AEVEGLGKGVARLSA
K1049 RLSAEAEKVLALPEP
K1073 ELELTLGKLEQVRSL
G1097 TISLVIRGTQGAEEV
T1098 ISLVIRGTQGAEEVL
K1113 RAHEEQLKEAQAVPA
K1273 EECQRFAKQYINAIK
K1280 KQYINAIKDYELQLV
Y1289 YELQLVTYKAQLEPV
K1290 ELQLVTYKAQLEPVA
S1298 AQLEPVASPAKKPKV
T1328 THYSELTTLTSQYIK
Y1333 LTTLTSQYIKFISET
K1371 EVEAALEKQRQLAEA
S1428 ELQQLRQSSEAEIQA
K1436 SEAEIQAKARQAEAA
R1490 EEAEAQKRQAQEEAE
R1500 QEEAERLRRQVQDEs
S1507-p RRQVQDEsQRKRQAE
K1581 AEAELQSKRASFAEK
S1584 ELQSKRASFAEKTAQ
S1595 KTAQLERSLQEEHVA
R1675 EAEREARRRGKAEEQ
S1770 EMEVLLASKARAEEE
K1771 MEVLLASKARAEEES
T1846 LAAIGEATRLKTEAE
T1916 QKGLVEDTLRQRRQV
K2045 LAQEAAQKRLQAEEK
K2052 KRLQAEEKAHAFAVQ
K2118-a VEEAERLkQSAEEQA
K2137-a QAQAAAEkLRKEAEQ
K2213 DEELQRLKAEATEAA
T2217 QRLKAEATEAARQRS
S2224 TEAARQRSQVEEELF
S2379 RQRQLEMSAEAERLK
S2441 LEIQRQQSDHDAERL
K2467 EKLQQEAKLLQLKSE
T2478 LKSEEMQTVQQEQLL
K2499 QQSFLSEKDSLLQRE
K2513 ERFIEQEKAKLEQLF
K2526 LFQDEVAKAQQLREE
S2551 ERQRLVASMEEARRR
S2618 HSEEVTASQVAATKT
A2637 RDALDGPAAEAEPEH
S2654 DGLRRKVSAQRLQEA
S2665 LQEAGILSAEELQRL
R2689 LARREDVRHYLQGRS
K2704 SIAGLLLKATNEKLS
K2704 SIAGLLLKATNEKLS
T2749-p PVRNRRLtVNEAVKE
K2778 ERAVTGYKDPYTGQQ
T2812 LLEAQIATGGVIDPV
K2851 ADPSDDTKGFFDPNT
K2890 PLTDKAAKGGELVyT
Y2896-p AKGGELVyTDSEARD
K2916 TVSAPFGKFQGKTVT
K2954 TGRITVEKIIKIIIT
Y2997 RVIDRELYQQLQRGE
T3015 RDVAEVDTVRRALRG
Y3041 AGQKLSIYNALKKDL
S3051 LKKDLLPSDMAVALL
K3100 EKLLSAEKAVTGYRD
Y3109 VTGYRDPYTGQSVSL
S3115 PYTGQSVSLFQALKK
S3139 RLLDAQLSTGGIVDP
T3140 LLDAQLSTGGIVDPS
S3147 TGGIVDPSKSHRVPL
E3165 CARGCLDEETSRALS
K3179 SAPRADAKAYSDPST
Y3192 STGEPATYGELQQRC
K3215 SLLPLSEKAARARQE
Y3225-p RARQEELySELQARE
P3238 RETFEKTPVEVPVGG
K3247 EVPVGGFKGRTVTVW
Y3261 WELISSEYFTAEQRQ
T3263 LISSEYFTAEQRQEL
K3283 TGKVTVEKVIKILIT
T3290 KVIKILITIVEEVET
S3320 PASELLASGVLSRAQ
G3321 ASELLASGVLSRAQF
S3324 LLASGVLSRAQFEQL
T3349 SELGSVRTLLQGSGC
S3354 VRTLLQGSGCLAGIY
Y3361 SGCLAGIYLEDTKEK
K3366 GIYLEDTKEKVSIYE
Y3372 TKEKVSIYEAMRRGL
R3377 SIYEAMRRGLLRATT
K3453 SLFQAMQKGLVLRQH
K3510 ADPSDDTKGFFDPNT
T3629 IIEIIEKTEIIRQQG
S3639 IRQQGLASYDYVRRR
Y3640 RQQGLASYDYVRRRL
Y3642 QGLASYDYVRRRLTA
T3648 DYVRRRLTAEDLFEA
F3653 RLTAEDLFEARIISL
T3662 ARIISLETYNLLREG
T3670 YNLLREGTRSLREAL
Y3696 TGSVAGVYLPGSRQT
Y3707 SRQTLSIYQALKKGL
T3793 MKKELIPTEEALRLL
K3831 YQRGYLNKDTHDQLS
T3870 RCRRDDGTGQLLLPL
T3884 LSDARKLTFRGLRKQ
K3890 LTFRGLRKQITMEEL
T3893 RGLRKQITMEELVRS
S3900 TMEELVRSQVMDEAT
S3917 QLREGLTSIEEVTKN
K3923 TSIEEVTKNLQKFLE
K3944 GVFVDATKERLSVYQ
K3984 IDPIKGLKLTVEEAV
K4001 GIVGPEFKDKLLSAE
K4015 ERAVTGYKDPySGKL
Y4018-p VTGYKDPySGKLISL
K4021 YKDPySGKLISLFQA
K4030 ISLFQAMKKGLILKD
K4068 LPVEVAYKRGLFDEE
K4068 LPVEVAYKRGLFDEE
T4130-p EKKRERKtssKSsVR
S4131-p KKRERKtssKSsVRK
S4132-p KRERKtssKSsVRKR
S4134 ERKtssKSsVRKRRV
S4135-p RKtssKSsVRKRRVV
T4148 VVIVDPETGKEMSVY
K4150 IVDPETGKEMSVYEA
R4159 MSVYEAYRKGLIDHQ
S4192 SSDGVVKSMIIDRRS
S4199 SMIIDRRSGRQYDID
Y4203 DRRSGRQYDIDDAIA
K4211 DIDDAIAKNLIDRSA
S4217 AKNLIDRSALDQYRA
T4230 RAGTLSITEFADMLS
S4237 TEFADMLSGNAGGFR
S4245-p GNAGGFRsRsssVGs
S4247-p AGGFRsRsssVGsss
S4248-p GGFRsRsssVGssss
S4249-p GFRsRsssVGssssy
S4252-p sRsssVGssssyPIs
S4253-p RsssVGssssyPIsP
S4254-p sssVGssssyPIsPA
S4255-p ssVGssssyPIsPAV
Y4256-p sVGssssyPIsPAVs
S4259-p ssssyPIsPAVsRTQ
P4260 sssyPIsPAVsRTQL
S4263-p yPIsPAVsRTQLASW
T4265 IsPAVsRTQLASWSD
S4269 VsRTQLASWSDPTEE
S4271 RTQLASWSDPTEETG
K4343 VNKGLVDKIMVDRIN
K4354 DRINLAQKAFCGFED
T4364 CGFEDPRTKTKMSAA
K4376 SAAQALKKGWLYYEA
Y4380 ALKKGWLYYEAGQRF
Y4381 LKKGWLYYEAGQRFL
T4402 GGLIEPDTPGRVPLD
G4429 AQKLRDVGAYSKYLT
K4472 EAAAQSTKGyySPyS
Y4474-p AAQSTKGyySPySVS
Y4475-p AQSTKGyySPySVSG
S4476 QSTKGyySPySVSGS
Y4478-p TKGyySPySVSGSGS
S4479 KGyySPySVSGSGST
S4481 yySPySVSGSGSTAG
S4483 SPySVSGSGSTAGSR
S4485 ySVSGSGSTAGSRTG
T4486 SVSGSGSTAGSRTGS
S4489 GSGSTAGSRTGSRTG
T4491 GSTAGSRTGSRTGSR
S4493 TAGSRTGSRTGSRAG
R4494 AGSRTGSRTGSRAGS
T4495 GSRTGSRTGSRAGSR
S4497 RTGSRTGSRAGSRRG
S4501 RTGSRAGSRRGsFDA
S4505-p RAGSRRGsFDATGSG
T4509 RRGsFDATGSGFSMT
S4511 GsFDATGSGFSMTFS
T4516 TGSGFSMTFSSSSYS
S4519 GFSMTFSSSSYSSSG
Y4522 MTFSSSSYSSSGYGR
S4523 TFSSSSYSSSGYGRR
Y4527 SSYSSSGYGRRYASG
S4533 GYGRRYASGSSASLG
S4535 GRRYASGSSASLGGP
S4538 YASGSSASLGGPESA
  plectin 1 iso6  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S2-p ______MsGAGGAFA
Y35-p PARRGYLyQQLCCVD
- gap
- gap
- gap
- gap
- gap
K54 VQKKTFTKWVNKHLI
S68 IKAQRHISDLYEDLR
S151 IILHFQISDIQVSGQ
S172 KEKLLLWSQRMVEGY
T218 MNKVYRQTNLENLDQ
S228 ENLDQAFSVAERDLG
S261 SIITYVSSLYDAMPR
Y263 ITYVSSLYDAMPRVP
K329 WSQFLKFKEMELPAK
K336 KEMELPAKEADKNRS
K344 EADKNRSKGIYQSLE
Y347 KNRSKGIYQSLEGAV
K360 AVQAGQLKVPPGYHP
K448 EVERDLDKADSMIRL
K464 FNDVQTLKDGRHPQG
Y475 HPQGEQMYRRVYRLH
Y479 EQMYRRVYRLHERLV
K497 TEYNLRLKAGVAAPA
T505 AGVAAPATQVAQVTL
S587 RSDEGQLSPATRGAY
T590 EGQLSPATRGAYRDC
K607 RLDLQYAKLLNSSKA
S649 EEVGFDWSDRNTNMT
S663 TAKKESYSALMRELE
A682 KIKELQNAGDRLLRE
Y728 HLKENAAYFQFFSDV
S754 EALRRKYSCDRSATV
S758 RKYSCDRSATVTRLE
K775 LQDAQDEKEQLNEYK
K775 LQDAQDEKEQLNEYK
Y781 EKEQLNEYKGHLSGL
K782 KEQLNEYKGHLSGLA
S786 NEYKGHLSGLAKRAK
K820 LLAVCDYKQVEVTVH
S914 VQLIRSWSLATFRTL
Y962 RLMAEREYGSCSHHY
K1032 QRIAEQQKAQAEVEG
K1042 AEVEGLGKGVARLSA
K1053 RLSAEAEKVLALPEP
K1077 ELELTLGKLEQVRSL
G1101 TISLVIRGTQGAEEV
T1102 ISLVIRGTQGAEEVL
K1117 RAHEEQLKEAQAVPA
K1277 EECQRFAKQYINAIK
K1284 KQYINAIKDYELQLV
Y1293 YELQLVTYKAQLEPV
K1294 ELQLVTYKAQLEPVA
S1302 AQLEPVASPAKKPKV
T1332 THYSELTTLTSQYIK
Y1337 LTTLTSQYIKFISET
K1375 EVEAALEKQRQLAEA
S1432 ELQQLRQSSEAEIQA
K1440 SEAEIQAKARQAEAA
R1494 EEAEAQKRQAQEEAE
R1504 QEEAERLRRQVQDES
S1511 RRQVQDESQRKRQAE
K1585 AEAELQSKRASFAEK
S1588 ELQSKRASFAEKTAQ
S1599 KTAQLERSLQEEHVA
R1679 EAEREARRRGKAEEQ
S1774 EMEVLLASKARAEEE
K1775 MEVLLASKARAEEES
T1850 LAAIGEATRLKTEAE
T1920 QKGLVEDTLRQRRQV
K2049 LAQEAAQKRLQAEEK
K2056 KRLQAEEKAHAFAVQ
K2122-a VEEAERLkQSAEEQA
K2141-a QAQAAAEkLRKEAEQ
K2217 DEELQRLKAEATEAA
T2221 QRLKAEATEAARQRS
S2228 TEAARQRSQVEEELF
S2383 RQRQLEMSAEAERLK
S2445 LEIQRQQSDHDAERL
K2471 EKLQQEAKLLQLKSE
T2482 LKSEEMQTVQQEQLL
K2503 QQSFLSEKDSLLQRE
K2517 ERFIEQEKAKLEQLF
K2530 LFQDEVAKAQQLREE
S2555 ERQRLVASMEEARRR
S2622 HSEEVTASQVAATKT
A2641 RDALDGPAAEAEPEH
S2658 DGLRRKVSAQRLQEA
S2669 LQEAGILSAEELQRL
R2693 LARREDVRHYLQGRS
K2708 SIAGLLLKATNEKLS
K2708 SIAGLLLKATNEKLS
T2753-p PVRNRRLtVNEAVKE
K2782 ERAVTGYKDPYTGQQ
T2816 LLEAQIATGGVIDPV
K2855 ADPSDDTKGFFDPNT
K2894 PLTDKAAKGGELVYT
Y2900 AKGGELVYTDSEARD
K2920 TVSAPFGKFQGKTVT
K2958 TGRITVEKIIKIIIT
Y3001 RVIDRELYQQLQRGE
T3019 RDVAEVDTVRRALRG
Y3045 AGQKLSIYNALKKDL
S3055 LKKDLLPSDMAVALL
K3104 EKLLSAEKAVTGYRD
Y3113 VTGYRDPYTGQSVSL
S3119 PYTGQSVSLFQALKK
S3143 RLLDAQLSTGGIVDP
T3144 LLDAQLSTGGIVDPS
S3151 TGGIVDPSKSHRVPL
E3169 CARGCLDEETSRALS
K3183 SAPRADAKAYSDPST
Y3196 STGEPATYGELQQRC
K3219 SLLPLSEKAARARQE
Y3229 RARQEELYSELQARE
P3242 RETFEKTPVEVPVGG
K3251 EVPVGGFKGRTVTVW
Y3265 WELISSEYFTAEQRQ
T3267 LISSEYFTAEQRQEL
K3287 TGKVTVEKVIKILIT
T3294 KVIKILITIVEEVET
S3324 PASELLASGVLSRAQ
G3325 ASELLASGVLSRAQF
S3328 LLASGVLSRAQFEQL
T3353 SELGSVRTLLQGSGC
S3358 VRTLLQGSGCLAGIY
Y3365 SGCLAGIYLEDTKEK
K3370 GIYLEDTKEKVSIYE
Y3376 TKEKVSIYEAMRRGL
R3381 SIYEAMRRGLLRATT
K3457 SLFQAMQKGLVLRQH
K3514 ADPSDDTKGFFDPNT
T3633 IIEIIEKTEIIRQQG
S3643 IRQQGLASYDYVRRR
Y3644 RQQGLASYDYVRRRL
Y3646 QGLASYDYVRRRLTA
T3652 DYVRRRLTAEDLFEA
F3657 RLTAEDLFEARIISL
T3666 ARIISLETYNLLREG
T3674 YNLLREGTRSLREAL
Y3700 TGSVAGVYLPGSRQT
Y3711 SRQTLSIYQALKKGL
T3797 MKKELIPTEEALRLL
K3835 YQRGYLNKDTHDQLS
T3874 RCRRDDGTGQLLLPL
T3888 LSDARKLTFRGLRKQ
K3894 LTFRGLRKQITMEEL
T3897 RGLRKQITMEELVRS
S3904 TMEELVRSQVMDEAT
S3921 QLREGLTSIEEVTKN
K3927 TSIEEVTKNLQKFLE
K3948 GVFVDATKERLSVYQ
K3988 IDPIKGLKLTVEEAV
K4005 GIVGPEFKDKLLSAE
K4019 ERAVTGYKDPySGKL
Y4022-p VTGYKDPySGKLISL
K4025 YKDPySGKLISLFQA
K4034 ISLFQAMKKGLILKD
K4072 LPVEVAYKRGLFDEE
K4072 LPVEVAYKRGLFDEE
T4134-p EKKRERKtssKSsVR
S4135-p KKRERKtssKSsVRK
S4136-p KRERKtssKSsVRKR
S4138 ERKtssKSsVRKRRV
S4139-p RKtssKSsVRKRRVV
T4152 VVIVDPETGKEMSVY
K4154 IVDPETGKEMSVYEA
R4163 MSVYEAYRKGLIDHQ
S4196 SSDGVVKSMIIDRRS
S4203 SMIIDRRSGRQYDID
Y4207 DRRSGRQYDIDDAIA
K4215 DIDDAIAKNLIDRSA
S4221 AKNLIDRSALDQYRA
T4234 RAGTLSITEFADMLS
S4241 TEFADMLSGNAGGFR
S4249-p GNAGGFRsRsssVGs
S4251-p AGGFRsRsssVGsss
S4252-p GGFRsRsssVGssss
S4253-p GFRsRsssVGssssY
S4256-p sRsssVGssssYPIs
S4257-p RsssVGssssYPIsP
S4258-p sssVGssssYPIsPA
S4259-p ssVGssssYPIsPAV
Y4260 sVGssssYPIsPAVs
S4263-p ssssYPIsPAVsRTQ
P4264 sssYPIsPAVsRTQL
S4267-p YPIsPAVsRTQLASW
T4269 IsPAVsRTQLASWSD
S4273 VsRTQLASWSDPTEE
S4275 RTQLASWSDPTEETG
K4347 VNKGLVDKIMVDRIN
K4358 DRINLAQKAFCGFED
T4368 CGFEDPRTKTKMSAA
K4380 SAAQALKKGWLYYEA
Y4384 ALKKGWLYYEAGQRF
Y4385 LKKGWLYYEAGQRFL
T4406 GGLIEPDTPGRVPLD
G4433 AQKLRDVGAYSKYLT
K4476 EAAAQSTKGyySPyS
Y4478-p AAQSTKGyySPySVS
Y4479-p AQSTKGyySPySVSG
S4480 QSTKGyySPySVSGS
Y4482-p TKGyySPySVSGSGS
S4483 KGyySPySVSGSGST
S4485 yySPySVSGSGSTAG
S4487 SPySVSGSGSTAGSR
S4489 ySVSGSGSTAGSRTG
T4490 SVSGSGSTAGSRTGS
S4493 GSGSTAGSRTGSRTG
T4495 GSTAGSRTGSRTGSR
S4497 TAGSRTGSRTGSRAG
R4498 AGSRTGSRTGSRAGS
T4499 GSRTGSRTGSRAGSR
S4501 RTGSRTGSRAGSRRG
S4505 RTGSRAGSRRGsFDA
S4509-p RAGSRRGsFDATGSG
T4513 RRGsFDATGSGFSMT
S4515 GsFDATGSGFSMTFS
T4520 TGSGFSMTFSSSSYS
S4523 GFSMTFSSSSYSSSG
Y4526 MTFSSSSYSSSGYGR
S4527 TFSSSSYSSSGYGRR
Y4531 SSYSSSGYGRRYASG
S4537 GYGRRYASGSSASLG
S4539 GRRYASGSSASLGGP
S4542 YASGSSASLGGPESA
  plectin 1 iso9  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y22-p YEEVREKyKDERDRV
- gap
- gap
- gap
- gap
- gap
- gap
- gap
K36 VQKKTFTKWVNKHLI
S50 IKAQRHISDLYEDLR
S133 IILHFQISDIQVSGQ
S154 KEKLLLWSQRMVEGY
T200 MNKVYRQTNLENLDQ
S210 ENLDQAFSVAERDLG
S243 SIITYVSSLYDAMPR
Y245 ITYVSSLYDAMPRVP
K311 WSQFLKFKEMELPAK
K318 KEMELPAKEADKNRS
K326 EADKNRSKGIYQSLE
Y329 KNRSKGIYQSLEGAV
K342 AVQAGQLKVPPGYHP
K430 EVERDLDKADSMIRL
K446 FNDVQTLKDGRHPQG
Y457 HPQGEQMYRRVYRLH
Y461 EQMYRRVYRLHERLV
K479 TEYNLRLKAGVAAPA
T487 AGVAAPATQVAQVTL
S569 RSDEGQLSPATRGAY
T572 EGQLSPATRGAYRDC
K589 RLDLQYAKLLNSSKA
S631 EEVGFDWSDRNTNMT
S645 TAKKESYSALMRELE
A664 KIKELQNAGDRLLRE
Y710 HLKENAAYFQFFSDV
S736 EALRRKYSCDRSATV
S740 RKYSCDRSATVTRLE
K757 LQDAQDEKEQLNEYK
K757 LQDAQDEKEQLNEYK
Y763 EKEQLNEYKGHLSGL
K764 KEQLNEYKGHLSGLA
S768 NEYKGHLSGLAKRAK
K802 LLAVCDYKQVEVTVH
S896 VQLIRSWSLATFRTL
Y944 RLMAEREYGSCSHHY
K1014 QRIAEQQKAQAEVEG
K1024 AEVEGLGKGVARLSA
K1035