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C/EBP-delta
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1. Interacts with PRDM16. Belongs to the bZIP family. C/EBP subfamily. Note: This description may include information from UniProtKB.
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| Protein type: DNA binding protein; Motility/polarity/chemotaxis |
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Cellular Component: nucleus
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Molecular Function: sequence-specific DNA binding; transcription factor activity
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Biological Process: transcription from RNA polymerase II promoter
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Reference #:
P49716 (UniProtKB)
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| Alt. Names/Synonyms: C/EBP delta; C/EBP-delta; CCAAT/enhancer binding protein (C/EBP), delta; CCAAT/enhancer-binding protein delta; CEBPD; CELF; CRP3; NF-IL6-beta; Nuclear factor NF-IL6-beta |
| Gene Symbols: CEBPD |
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Molecular weight: 28,467 Da
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Basal Isoelectric point: 8.44
Predict pI for various phosphorylation states
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