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Protein Page:
C/EBP-delta (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
C/EBP-delta C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1. Interacts with PRDM16. Belongs to the bZIP family. C/EBP subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA binding protein; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 8p11.2-p11.1
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
Reference #:  P49716 (UniProtKB)
Alt. Names/Synonyms: C/EBP delta; C/EBP-delta; CCAAT/enhancer binding protein (C/EBP), delta; CCAAT/enhancer-binding protein delta; CEBPD; CELF; CRP3; NF-IL6-beta; Nuclear factor NF-IL6-beta
Gene Symbols: CEBPD
Molecular weight: 28,467 Da
Basal Isoelectric point: 8.44  Predict pI for various phosphorylation states
Select Structure to View Below

C/EBP-delta

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 G10 AALFSLDGPARGAPW
2 0 K120-sm PAAPRLLkREPDWGD
1 0 K120-ac PAAPRLLkREPDWGD
1 0 S167-p SPEPPRSsPRQtPAP
1 0 T171-p PRSsPRQtPAPGPAR
0 1 S191-p KRGPDRGsPEYRQRR
0 2 S256-p QFFKQLPsPPFLPAA
  mouse

 
S10-p AALFSLDsPVRGTPW
K120-sm SVARGPLkREPDWGD
K120 SVARGPLKREPDWGD
S167 SPEPPRGSPGPSLAP
S171 PRGSPGPSLAPGTVR
S191 KRGPDRGSPEYRQRR
S256-p QFFKKLPsPPFLPPT
  rat

 
S10-p AALFSLDsPARGAPW
K120 SIARGPLKREPDWGD
K120 SIARGPLKREPDWGD
S167 SPEPPRGSPGPSLAP
S171 PRGSPGPSLAPGPVR
S191 KRGPDRGSPEYRQRR
S256 QFFKELPSPPFLPPT
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