Major acute phase reactant. Apolipoprotein of the HDL complex. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. Belongs to the SAA family. Note: This description may include information from UniProtKB.
Alt. Names/Synonyms: Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Serum amyloid A protein; serum amyloid A1; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); TP53I4; tumor protein p53 inducible protein 4
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.