Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
LTBR (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
LTBR Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Cellular Component: integral to membrane
Molecular Function: identical protein binding; protein binding; ubiquitin protein ligase binding
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; viral reproduction; apoptosis; positive regulation of JNK cascade; signal transduction
Reference #:  P36941 (UniProtKB)
Alt. Names/Synonyms: CD18; D12S370; LT-BETA-R; LTBR; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); Lymphotoxin-beta receptor; TNF-R-III; TNF-RIII; TNFCR; TNFR superfamily, member 3; TNFR-III; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3; TNR3; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; Tumor necrosis factor receptor type III
Gene Symbols: LTBR
Molecular weight: 46,709 Da
Basal Isoelectric point: 5.53  Predict pI for various phosphorylation states
CST Pathways:  NF-kB Signaling
Select Structure to View Below

LTBR

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Source  |  InnateDB  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S260-p SLCRKLGsLLKRRPQ
0 1 S323-p AGVPQQQsPLDLTRE
0 1 T421-gl ETEHCGAtPsNRGPR
0 1 S423-gl EHCGAtPsNRGPRNQ
  mouse

 
T256 SLCRKLGTLLKRHPE
S315 EVVLQQQSPLVQARE
- gap
- gap
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.