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PCM-1 (human)

Overview PCM-1 a pericentriolar protein of unknown function. Note: This description may include information from UniProtKB. Protein type: Cell cycle regulation Cellular Component: centrosome; pericentriolar material; nuclear membrane; nonmotile primary cilium; cytoplasm; cytosol Molecular Function: identical protein binding; protein binding Biological Process: centrosome organization and biogenesis; cilium biogenesis; mitotic cell cycle; G2/M transition of mitotic cell cycle; interkinetic nuclear migration; negative regulation of neurogenesis Reference #:  Q15154 (UniProtKB) Alt. Names/Synonyms: hPCM-1; PCM-1; PCM1; pericentriolar material 1; Pericentriolar material 1 protein; PTC4 Gene Symbols: PCM1 Molecular weight: 228,533 Da Basal Isoelectric point: 4.95  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below PCM-1

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  DISEASE 188550 600299  |  InnateDB  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human ► Hide Isoforms
0	1		K39-u	MDWGAQQkKANRSSE
0	1		K51-u	SSEKNKKkFGVESDK
0	1		T61-p	VESDKRVtNDIsPEs
0	135		S65-p	KRVtNDIsPEssPGV
0	78		S68-p	tNDIsPEssPGVGRR
0	68		S69-p	NDIsPEssPGVGRRR
0	4		T79-p	VGRRRTKtPHtFPHS
0	3		T82-p	RRTKtPHtFPHSRyM
0	4		Y88-p	HtFPHSRyMsQMsVP
0	4		S90-p	FPHSRyMsQMsVPEQ
0	36		S93-p	SRyMsQMsVPEQAEL
0	5		K102-u	PEQAELEkLkQRINF
0	2		K104-u	QAELEkLkQRINFsD
0	19		S110-p	LkQRINFsDLDQRsI
0	7		S116-p	FsDLDQRsIGsDsQG
0	7		S119-p	LDQRsIGsDsQGRAt
0	3		S121-p	QRsIGsDsQGRAtAA
0	2		T126-p	sDsQGRAtAANNKRQ
0	3		K139-u	RQLSENRkPFNFLPM
0	1		K152-u	PMQINTNkSKDASTS
0	2		K172-u	TIGSAQCkELFAsAL
0	1		S177-p	QCkELFAsALsNDLL
0	2		S180-p	ELFAsALsNDLLQNC
0	2		S203-p	GEPAMESsQIVSRLV
0	3		Y215-p	RLVQIRDyITkASSM
0	2		K218-u	QIRDyITkASSMRED
0	1		K229-u	MREDLVEkNERSANV
0	1		K255-u	EQEKSYMkFLKKILA
0	8		K259	SYMkFLKKILARDPQ
0	4		K277-u	MEEIENLkkQHDLLK
0	3		K278-u	EEIENLkkQHDLLKR
0	1		K309	ALLALQHKAEQAIAV
0	1		S320-p	AIAVMDDsVVAETAG
0	1		S356-p	FHNQLRDsQPPAVPD
0	1		S370-p	DNRRQAEsLsLtREV
0	14		S372-p	RRQAEsLsLtREVsQ
0	2		T374-p	QAEsLsLtREVsQsR
0	1		S378-p	LsLtREVsQsRKPsA
0	2		S380-p	LtREVsQsRKPsASE
0	12		S384-p	VsQsRKPsASERLPD
0	48		K393-u	SERLPDEkVELFSkM
0	1		K399-a	EkVELFSkMRVLQEK
0	5		K399-u	EkVELFSkMRVLQEK
0	1		K407-a	MRVLQEKkQkMDkLL
0	1		K409-a	VLQEKkQkMDkLLGE
0	1		K409-u	VLQEKkQkMDkLLGE
0	29		K412-u	EKkQkMDkLLGELHt
0	8		T419-p	kLLGELHtLRDQHLN
0	5		S428-p	RDQHLNNssssPQRs
0	4		S429-p	DQHLNNssssPQRsV
0	1		S430-p	QHLNNssssPQRsVD
0	8		S431-p	HLNNssssPQRsVDQ
0	2		S435-p	ssssPQRsVDQRSTS
0	12		K492-u	NPSEKLQkLNEVRKR
0	1		Y509-p	ELRELVHyYEQTSDM
0	6		T530-p	ENRKDEEtEEsEYDs
0	4		S533-p	KDEEtEEsEYDsEHE
0	6		S537-p	tEEsEYDsEHENsEP
0	2		S542-p	YDsEHENsEPVTNIR
0	2		T556-p	RNPQVAStWNEVNSH
0	1		S580-p	RDGRTVNsNCEINNR
0	6		S643	ASLSSHRSSLVDEHP
0	9		S644	SLSSHRSSLVDEHPE
0	1		K658-u	EDAEFEQkINRLMAA
0	2		Y700-p	ASNLDDFyPAEEDTk
0	6		K707-u	yPAEEDTkQNSNNTR
0	2		K719	NTRGNANKtQkDtGV
0	1		T720-p	TRGNANKtQkDtGVN
0	1		K722-u	GNANKtQkDtGVNEk
0	1		T724-p	ANKtQkDtGVNEkAR
0	3		K729-u	kDtGVNEkAREkFyE
0	1		K733-u	VNEkAREkFyEAkLQ
0	13		Y735-p	EkAREkFyEAkLQQQ
0	33		K738-u	REkFyEAkLQQQQRE
0	7		K762-u	KLIDIQEkIQALQTA
0	9		T768	EkIQALQTACPDLQL
0	4		S776-p	ACPDLQLsAAsVGNC
0	1		A778	PDLQLsAAsVGNCPt
0	4		S779-p	DLQLsAAsVGNCPtk
0	1		G781	QLsAAsVGNCPtkkY
0	1		N782	LsAAsVGNCPtkkYM
0	2		T785-p	AsVGNCPtkkYMPAV
0	23		K786-u	sVGNCPtkkYMPAVT
0	19		K787-u	VGNCPtkkYMPAVTs
0	2		S794-p	kYMPAVTstPtVNQH
0	2		T795-p	YMPAVTstPtVNQHE
0	4		T797-p	PAVTstPtVNQHETS
0	1		T803	PtVNQHETSTSkSVF
0	1		T805	VNQHETSTSkSVFEP
0	1		S806	NQHETSTSkSVFEPE
0	1		K807-u	QHETSTSkSVFEPED
0	7		K841-u	EELRQRRkQLEALMA
0	2		T859-p	RRQGLAEtAsPVAVs
0	1		A860	RQGLAEtAsPVAVsL
0	12		S861-p	QGLAEtAsPVAVsLR
0	5		S866-p	tAsPVAVsLRsDGsE
0	4		S869-p	PVAVsLRsDGsENLC
0	5		S872-p	VsLRsDGsENLCtPQ
0	6		T877-p	DGsENLCtPQQsRTE
0	1		S881-p	NLCtPQQsRTEKTMA
0	1		K954-u	KETKNRWkNNCPFsA
0	41		S960-p	WkNNCPFsADENyRP
0	128		Y965-p	PFsADENyRPLAkTR
0	26		K970-u	ENyRPLAkTRQQNIS
0	1		T971	NyRPLAkTRQQNISM
0	4		S988-p	QENLRWVsELsyVEE
0	18		S991-p	LRWVsELsyVEEkEQ
0	2		Y992-p	RWVsELsyVEEkEQW
0	3		K996-u	ELsyVEEkEQWQEQI
0	1		K1007-u	QEQINQLkKQLDFSV
0	10		K1076-u	QNNVQRLkQMLNELM
0	3		K1092-u	QQNQHPEkPGGkERG
0	12		K1096-u	HPEkPGGkERGSSAS
0	4		S1107-p	SSASHPPsPSLFCPF
0	30		T1174-p	AQNSSGKtEyMAFPk
0	221		Y1176-p	NSSGKtEyMAFPkPF
0	17		K1181-u	tEyMAFPkPFEsSss
0	10		S1185-p	AFPkPFEsSssIGAE
0	2		S1186	FPkPFEsSssIGAEk
0	8		S1187-p	PkPFEsSssIGAEkP
0	11		S1188-p	kPFEsSssIGAEkPR
0	12		K1193-u	SssIGAEkPRNkkLP
0	2		K1197-u	GAEkPRNkkLPEEEV
0	23		K1198-u	AEkPRNkkLPEEEVE
0	3		R1208	EEEVESSRtPWLyEQ
0	3		T1209-p	EEVESSRtPWLyEQE
0	17		Y1213-p	SSRtPWLyEQEGEVE
0	11		K1221-u	EQEGEVEkPFIkTGF
0	5		K1225-u	EVEkPFIkTGFSVsV
0	2		S1231-p	IkTGFSVsVEKSTSS
0	46		S1257-p	RRQFDEEsLEsFssM
0	40		S1260-p	FDEEsLEsFssMPDP
0	19		S1262-p	EEsLEsFssMPDPVD
0	45		S1263-p	EsLEsFssMPDPVDP
0	1		T1271-p	MPDPVDPtTVTkTFK
0	1		K1275-u	VDPtTVTkTFKtRKA
0	1		T1279-p	TVTkTFKtRKAsAQA
0	7		S1283-p	TFKtRKAsAQAsLAs
0	3		S1287-p	RKAsAQAsLAskDKt
0	3		S1290-p	sAQAsLAskDKtPKS
0	1		K1291-u	AQAsLAskDKtPKSK
0	1		T1294-p	sLAskDKtPKSKSKK
0	1		T1305-p	KSKKRNStQLKSRVK
0	1		K1312	tQLKSRVKNIRyEsA
0	1		Y1316-p	SRVKNIRyEsASMSS
0	5		S1318-p	VKNIRyEsASMSSTC
0	1		S1320	NIRyEsASMSSTCEP
0	1		S1322	RyEsASMSSTCEPCK
0	1		S1323	yEsASMSSTCEPCKS
0	1		K1329	SSTCEPCKSRNRHsA
0	1		S1335-p	CKSRNRHsAQTEEPV
0	2		K1345-u	TEEPVQAkVFSRKNH
0	1		S1373-p	EISSETGsDFSMFEA
0	5		S1435-p	DIVSRHIsESHEkGE
0	3		S1437	VSRHIsESHEkGENV
0	2		K1440-u	HIsESHEkGENVKSV
0	1		T1451-p	VKSVNSGtWIASNSE
0	2		T1468-p	PSESLATtDDETFEK
0	2		S1494	QNDADNASVLsVSSN
0	4		S1497-p	ADNASVLsVSSNFEP
0	1		S1499	NASVLsVSSNFEPFA
0	1		S1500	ASVLsVSSNFEPFAT
0	4		Y1527-p	ALARMREyERMktEA
0	1		K1531-u	MREyERMktEAESNS
0	5		T1532-p	REyERMktEAESNSN
0	1		D1551-ca	CRIIEDGdGAGAGTt
0	1		T1558-p	dGAGAGTtVNNLEEt
0	9		T1565-p	tVNNLEEtPVIENRS
0	1		S1573	PVIENRSSQQPVSEV
0	1		T1590-p	IPCPRIDtQQLDRQI
0	2		K1602-u	RQIKAIMkEVIPFLK
0	1		K1639-u	TQQNDESkEFVKFFH
0	3		K1647-u	EFVKFFHkQLGSILQ
0	1		S1656	LGSILQDSLAkFAGR
0	2		K1659-u	ILQDSLAkFAGRKLK
0	1		S1697-p	MQDLDNNsITVkQRC
0	4		K1701-u	DNNsITVkQRCKRKI
0	15		S1730-p	RILEDHGsPAGEIDD
0	158		Y1757-p	QTQTSEVyDGPKNVR
0	31		S1765-p	DGPKNVRsDIsDQEE
0	31		S1768-p	KNVRsDIsDQEEDEE
0	15		S1776-p	DQEEDEEsEGCPVSI
0	1		S1782	EsEGCPVSINLSKAE
0	1		S1786	CPVSINLSKAETQAL
0	3		T1794-p	KAETQALtNyGsGED
0	1		Y1796-p	ETQALtNyGsGEDEN
0	4		S1798-p	QALtNyGsGEDENED
0	1		K1845-u	VLQRDFKkTAESkNV
0	1		T1846	LQRDFKkTAESkNVP
0	1		K1850-u	FKkTAESkNVPLERE
0	2		L1854	AESkNVPLEREAtsk
0	5		T1859-p	VPLEREAtskNDQNN
0	1		S1860-p	PLEREAtskNDQNNC
0	1		K1861-u	LEREAtskNDQNNCP
0	2		C1867	skNDQNNCPVKPCYL
0	1		Y1873	NCPVKPCYLNILEDE
0	9		Y1947-p	SPVLVNDyEAESGNI
0	8		S1958-p	SGNISQKsDEEDFVK
0	29		Y1976-p	LPLKLTIysEADLRK
0	8		S1977-p	PLKLTIysEADLRKK
0	1		S2023	PETVGAQSI______
0	1		-	gap

	PCM-1 iso3
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K53	KETKNRWKNNCPFSA
S59	WKNNCPFSADENYRP
Y64	PFSADENYRPLAKTR
K69	ENYRPLAKTRQQNIS
T70	NYRPLAKTRQQNISM
S87	QENLRWVSELSYVEE
S90	LRWVSELSYVEEKEQ
Y91	RWVSELSYVEEKEQW
K95	ELSYVEEKEQWQEQI
K106	QEQINQLKKQLDFSV
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T150-p	MNRSYNVtLKRQQKA

	mouse
K39	MEWGGQQKKANRSSE
K51	SSEKNKKKFGVASDK
T61	VASDKRVTNAIsPEs
S65-p	KRVTNAIsPEssPGV
S68-p	TNAIsPEssPGVGRR
S69-p	NAIsPEssPGVGRRR
I79	VGRRRTKIPHTFPHS
T82	RRTKIPHTFPHSRYM
Y88	HTFPHSRYMtQMsVP
T90-p	FPHSRYMtQMsVPEQ
S93-p	SRYMtQMsVPEQAEL
K102-u	PEQAELEkLkQRINF
K104-u	QAELEkLkQRINFsD
S110-p	LkQRINFsDLDQRsI
S116-p	FsDLDQRsIGsDSQG
S119-p	LDQRsIGsDSQGRAT
S121	QRsIGsDSQGRATAA
T126	sDSQGRATAANNKRQ
K139-u	RQLSENRkPFNFLPM
K152	PMQINTNKSKDATAS
K172	MTTSAQCKELFASAL
S177	QCKELFASALSNDLL
S180	ELFASALSNDLLQNC
S203	GEPAMESSQIVSRLV
Y215	RLVQIRDYITKASSM
K218	QIRDYITKASSMRED
K229	MREDLVEKNERSANV
K255	EQEKSYMKFLQkILA
K259-u	SYMKFLQkILARDPQ
K277-u	MEETENLkkQHDLLK
K278-u	EETENLkkQHDLLKR
K309-u	ALLALQHkAEQAIAV
S320	AIAVMDDSVVTETTG
S356	FHNQLRDSQPPAVPD
S370	DNRRQAESLSLTREI
S372	RRQAESLSLTREISQ
T374	QAESLSLTREISQSR
S378	LSLTREISQSRNPsV
S380	LTREISQSRNPsVSE
S384-p	ISQSRNPsVSEHLPD
K393-u	SEHLPDEkVQLFSkM
K399	EkVQLFSKMRVLQEK
K399-u	EkVQLFSkMRVLQEK
K407	MRVLQEKKQKMDkLL
K409	VLQEKKQKMDkLLGE
K409	VLQEKKQKMDkLLGE
K412-u	EKKQKMDkLLGELHN
N419	kLLGELHNLRDQHLN
S428	RDQHLNNSSFVPSTS
S429	DQHLNNSSFVPSTSL
T434	NSSFVPSTSLQRSGD
S435	SSFVPSTSLQRSGDK
S439	PSTSLQRSGDKRSST
K497	NPAEKLQKLNEVQKR
Y514	ELRELVHYYEQTSDM
T535	ENTKDEETEESEYDs
S538	KDEETEESEYDsEHE
S542-p	TEESEYDsEHENSEP
S547	YDsEHENSEPVTNIR
T561	RNPQVASTWNEVNTN
S585	RDGRPVNSNCEINNR
S644-p	ASLSSRRssLVDEAP
S645-p	SLSSRRssLVDEAPE
K659	EDEEFEQKISRLMAA
Y700	ASNLDDFYAAEEDIk
K707-u	YAAEEDIkQNSNNAR
K719-u	NARENSNkIDTGVNE
I720	ARENSNkIDTGVNEk
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T722	ENSNkIDTGVNEkTR
K727-u	IDTGVNEkTREKFYE
K731	VNEkTREKFYEAkLQ
Y733	EkTREKFYEAkLQQQ
K736-u	REKFYEAkLQQQQRE
K760-u	KLIEIQEkIQAVQkA
K766-u	EkIQAVQkACPDLQL
S774-p	ACPDLQLsAtsIssG
T776-p	PDLQLsAtsIssGPt
S777-p	DLQLsAtsIssGPtK
S779-p	QLsAtsIssGPtKkY
S780-p	LsAtsIssGPtKkYL
T783-p	tsIssGPtKkYLPAI
K784	sIssGPtKkYLPAIT
K785-u	IssGPtKkYLPAITS
S792	kYLPAITSTPTVNEN
T793	YLPAITSTPTVNEND
T795	PAITSTPTVNENDsS
S801-p	PTVNENDsStsKCVI
T803-p	VNENDsStsKCVIDP
S804-p	NENDsStsKCVIDPE
K805	ENDsStsKCVIDPED
K839	EELRQRRKQLEALMA
T857-p	RRQGLAEtssPVAIs
S858-p	RQGLAEtssPVAIsL
S859-p	QGLAEtssPVAIsLR
S864-p	tssPVAIsLRsDGsE
S867-p	PVAIsLRsDGsENLC
S870-p	IsLRsDGsENLCtPQ
T875-p	DGsENLCtPQQSRTE
S879	NLCtPQQSRTEKTMA
K951	KETKTRWKSNRPVsA
S957-p	WKSNRPVsADGNyRP
Y962-p	PVsADGNyRPLAktR
K967-u	GNyRPLAktRQQNIS
T968-p	NyRPLAktRQQNISM
S985-p	QENLRWVsELsYIEE
S988-p	LRWVsELsYIEEKEQ
Y989	RWVsELsYIEEKEQW
K993	ELsYIEEKEQWQEQI
K1004	QEQINQLKKQLDFSV
K1073-u	QNNVQRLkQMLTELM
K1089-u	QQNQHPEkPRSKERG
K1093	HPEkPRSKERGSSAS
S1104	SSASHPSSPNLFCPF
T1171	AQNPSGKTEyMAFPk
Y1173-p	NPSGKTEyMAFPkPF
K1178-u	TEyMAFPkPFEssss
S1182-p	AFPkPFEssssLGAE
S1183-p	FPkPFEssssLGAEk
S1184-p	PkPFEssssLGAEkQ
S1185-p	kPFEssssLGAEkQR
K1190-u	sssLGAEkQRNQKQP
Q1194	GAEkQRNQKQPEEEA
K1195	AEkQRNQKQPEEEAE
K1205-u	EEEAENTkTPWLYDQ
T1206	EEAENTkTPWLYDQE
Y1210	NTkTPWLYDQEGGVE
K1218	DQEGGVEKPFFKTGF
K1222	GVEKPFFKTGFTEsV
S1228-p	FKTGFTEsVEKATNS
S1254-p	RRQFDEEsLEsFssM
S1257-p	FDEEsLEsFssMPDP
S1259-p	EEsLEsFssMPDPID
S1260-p	EsLEsFssMPDPIDP
T1268	MPDPIDPTTVTKTFK
K1272	IDPTTVTKTFKTRKA
T1276	TVTKTFKTRKAsAQA
S1280-p	TFKTRKAsAQAsLAs
S1284-p	RKAsAQAsLAsKDKT
S1287-p	sAQAsLAsKDKTPKS
K1288	AQAsLAsKDKTPKSK
T1291	sLAsKDKTPKSKSKK
T1302	KSKKRNSTQLKSRVk
K1309-u	TQLKSRVkNIGYEsA
Y1313	SRVkNIGYEsAsVss
S1315-p	VkNIGYEsAsVssTC
S1317-p	NIGYEsAsVssTCEP
S1319-p	GYEsAsVssTCEPCk
S1320-p	YEsAsVssTCEPCkN
K1326-u	ssTCEPCkNRNRHSA
S1332	CkNRNRHSAQTEEPV
K1342	TEEPVQAKLFSRKNH
S1370	EISSETGSDFSMFEA
S1432-p	DIVSRHIsEsDEREG
S1434-p	VSRHIsEsDEREGEN
R1437	HIsEsDEREGENVKP
T1449	VKPVNSGTWVASNSE
T1466	PSESLVTTDDETFEK
S1492-p	QNDADNVsVMsVssN
S1495-p	ADNVsVMsVssNFEP
S1497-p	NVsVMsVssNFEPFA
S1498-p	VsVMsVssNFEPFAT
Y1525	ALARMREYERMKTET
K1529	MREYERMKTETESHS
T1530	REYERMKTETESHSN
D1549	CRVIEDEDGAAAAAT
T1556	DGAAAAATVSNSEET
T1563	TVSNSEETPIIENHN
S1571-p	PIIENHNsPQPISDV
T1588	VPCPRIDTQQLDRQI
K1600	RQIKAIMKEVIPFLK
K1637	TQQNDESKEFVKFFH
K1645	EFVKFFHKQLGSILQ
S1654-p	LGSILQDsLAKFAGR
K1657	ILQDsLAKFAGRKLK
S1695	MQDLDNNSIAVKQRC
K1699	DNNSIAVKQRCKRKI
S1729-p	ILEGDHGsPAGEIDD
Y1756	QTQTSEVYDAKGPKN
S1766-p	KGPKNVRsDVsDQEE
S1769-p	KNVRsDVsDQEEDEE
S1777-p	DQEEDEEsERCPVsI
S1783-p	EsERCPVsINLsKAE
S1787-p	CPVsINLsKAESQAL
T1795	KAESQALTNYGSGED
Y1797	ESQALTNYGSGEDEN
S1799	QALTNYGSGEDENED
K1846	ILQHDLEKtPESTNV
T1847-p	LQHDLEKtPESTNVP
T1851	LEKtPESTNVPsDQE
S1855-p	PESTNVPsDQEPTSK
T1860	VPsDQEPTSKNDQDS
S1861	PsDQEPTSKNDQDSs
K1862	sDQEPTSKNDQDSsP
S1868-p	SKNDQDSsPVKPCyL
Y1874-p	SsPVKPCyLNILENE
Y1948-p	SPVLVNDyEAESGNI
S1959-p	SGNISQKsDEEDFVK
Y1977	LPLKLTVYSEEELRK
S1978	PLKLTVYSEEELRKK
S2024-p	PETVGAQsI______
-	gap

	rat
K39	MEWGGQQKKANRSSE
K51	SSEKNKKKFGVASDK
T61	VASDKRVTNDIsPEs
S65-p	KRVTNDIsPEssPGV
S68-p	TNDIsPEssPGVGRR
S69-p	NDIsPEssPGVGRRR
V79	VGRRRTKVPHTFPHS
T82	RRTKVPHTFPHSRYM
Y88	HTFPHSRYMTQMSVP
T90	FPHSRYMTQMSVPEQ
S93	SRYMTQMSVPEQAEL
K102	PEQAELEKLKQRINF
K104	QAELEKLKQRINFSD
S110	LKQRINFSDLDQRSI
S116	FSDLDQRSIGSDSQG
S119	LDQRSIGSDSQGRAT
S121	QRSIGSDSQGRATAA
T126	SDSQGRATAANNKRQ
K139	RQLGENRKPFNFLPM
K152	PMQINTNKSKDATAS
K172	TTTSAQCKELFASAL
S177	QCKELFASALSNDLL
S180	ELFASALSNDLLQNC
S203	GEPAMESSQIVSRLV
Y215	RLVQIRDYITKASSM
K218	QIRDYITKASSMRED
K229	MREDLVEKNERSANV
K255	EQEKSYMKFLQKILA
K259	SYMKFLQKILARENE
K316	MEETENLKKQHDLLK
K317	EETENLKKQHDLLKR
K348	ALLALQHKAEQAIAV
S359	AIAVMDDSVVTETTG
S395	FHNQLRDSQPPAVPD
S409	DNRRQAESLSLTREI
S411	RRQAESLSLTREISQ
T413	QAESLSLTREISQSR
S417	LSLTREISQSRNPSV
S419	LTREISQSRNPSVSE
S423	ISQSRNPSVSEHLPD
K432	SEHLPDEKVQLFSKM
K438	EKVQLFSKMRVLQEK
K438	EKVQLFSKMRVLQEK
K446	MRVLQEKKQKMDKLL
K448	VLQEKKQKMDKLLGE
K448	VLQEKKQKMDKLLGE
K451	EKKQKMDKLLGELHT
T458	KLLGELHTLRDQHLN
S467	RDQHLNNSSFVPSTS
S468	DQHLNNSSFVPSTSL
T473	NSSFVPSTSLPRSGD
S474	SSFVPSTSLPRSGDK
S478	PSTSLPRSGDKRSST
K536	NPAEKLQKLNEVQKR
Y553	ELRELVHYYEQTSDM
T574	ENTKDEETEESEYDS
S577	KDEETEESEYDSEHE
S581	TEESEYDSEHEHSEP
S586	YDSEHEHSEPVTNIR
T600	RNPQVASTWNEVNTN
S624	REGRSINSSCEINNR
S683	ASLSSRRSSLVDEAP
S684	SLSSRRSSLVDEAPE
K698	EDEEFEQKISRLMAA
Y739	ASNLDDFYVAEEDTK
K746	YVAEEDTKQNSNNAR
K758	NARENSNKVDTGVNE
V759	ARENSNKVDTGVNEK
-	gap
T761	ENSNKVDTGVNEKTR
K766	VDTGVNEKTREKFYE
K770	VNEKTREKFYEAKLQ
Y772	EKTREKFYEAKLQQQ
K775	REKFYEAKLQQQQRE
K799	KLIEIQEKIQAVQKA
K805	EKIQAVQKACPDLQL
S813	ACPDLQLSATSISSG
T815	PDLQLSATSISSGPT
S816	DLQLSATSISSGPTK
S818	QLSATSISSGPTKKY
S819	LSATSISSGPTKKYL
T822	TSISSGPTKKYLPAI
K823	SISSGPTKKYLPAIT
K824	ISSGPTKKYLPAITS
S831	KYLPAITSTPTVNEN
T832	YLPAITSTPTVNENE
T834	PAITSTPTVNENETS
T840	PTVNENETSTSKCDI
T842	VNENETSTSKCDIEP
S843	NENETSTSKCDIEPE
K844	ENETSTSKCDIEPED
K878	EELRQRRKQLEALMA
T896	RRQGLAETASPVAVS
A897	RQGLAETASPVAVSL
S898	QGLAETASPVAVSLR
S903	TASPVAVSLRSDGSE
S906	PVAVSLRSDGSENLG
S909	VSLRSDGSENLGTPQ
T914	DGSENLGTPQQSRTE
S918	NLGTPQQSRTEKTMA
K990	KETKNRWKNHRPVSA
S996	WKNHRPVSADGNYRP
Y1001	PVSADGNYRPLAKTR
K1006	GNYRPLAKTRQQNIS
T1007	NYRPLAKTRQQNISM
S1024	QENLRWVSELSYIEE
S1027	LRWVSELSYIEEKEQ
Y1028	RWVSELSYIEEKEQW
K1032	ELSYIEEKEQWQEQI
K1043	QEQINQLKKQLDFSV
K1112	QNNVQRLKQMLTELM
K1128	QQNQHPEKPRSKERG
K1132	HPEKPRSKERGSSAS
S1143	SSASHPSSPSLFCPF
T1210	AQNPSGKTEyMAFPK
Y1212-p	NPSGKTEyMAFPKPF
K1217	TEyMAFPKPFESSSS
S1221	AFPKPFESSSSLGAE
S1222	FPKPFESSSSLGAEK
S1223	PKPFESSSSLGAEKQ
S1224	KPFESSSSLGAEKQR
K1229	SSSLGAEKQRNQKQP
Q1233	GAEKQRNQKQPEEET
K1234	AEKQRNQKQPEEETE
K1244	EEETENTKTPWLYDQ
T1245	EETENTKTPWLYDQE
Y1249	NTKTPWLYDQEGGVE
K1257	DQEGGVEKPFFKTGF
K1261	GVEKPFFKTGFAVSV
S1267	FKTGFAVSVEKATNS
S1293	GRQFDEESLESFSSM
S1296	FDEESLESFSSMPDP
S1298	EESLESFSSMPDPID
S1299	ESLESFSSMPDPIDP
T1307	MPDPIDPTTVTKTFK
K1311	IDPTTVTKTFKTRKA
T1315	TVTKTFKTRKASAQA
S1319	TFKTRKASAQASLAS
S1323	RKASAQASLASKDKT
S1326	SAQASLASKDKTPKS
K1327	AQASLASKDKTPKSK
T1330	SLASKDKTPKSKSKK
T1341	KSKKRNSTQLKSRVK
K1348	TQLKSRVKTIGYESA
Y1352	SRVKTIGYESASVSS
S1354	VKTIGYESASVSSTC
S1356	TIGYESASVSSTCEP
S1358	GYESASVSSTCEPCK
S1359	YESASVSSTCEPCKS
K1365	SSTCEPCKSRNRHSA
S1371	CKSRNRHSAQTEEPV
K1381	TEEPVQAKLFSRKNH
S1409	EISSETGSDFSMFEA
S1471-p	DIVSRHIsESDEKEG
S1473	VSRHIsESDEKEGEN
K1476	HIsESDEKEGENIKS
T1488	IKSVNSGTWVASNSE
T1505	PSESLVTTDDETFEK
S1531	QNDADNVSVMSVSSN
S1534	ADNVSVMSVSSNFEP
S1536	NVSVMSVSSNFEPFA
S1537	VSVMSVSSNFEPFAT
Y1564	ALARMREYERMKTET
K1568	MREYERMKTETESNS
T1569	REYERMKTETESNSN
D1588	CRVIEDEDGAAATTT
T1595	DGAAATTTVSNAEET
T1602	TVSNAEETPIIENHS
S1610	PIIENHSSPQPTSDV
T1627	VPCPRIDTQQLDRQI
K1639	RQIKAIMKEVIPFLK
K1676	TQQNDESKEFVKFFH
K1684	EFVKFFHKQLGSILQ
S1693	LGSILQDSLAKFAGR
K1696	ILQDSLAKFAGRKLK
S1734	MQDLDNNSIAVKQRC
K1738	DNNSIAVKQRCKRKI
S1768	ILEGDRGSPAGEIDD
Y1795	QTQTSEVYDAKGPKN
S1805	KGPKNVRSDVSDQEE
S1808	KNVRSDVSDQEEDEE
S1816	DQEEDEESERCPVSI
S1822	ESERCPVSINLSKAE
S1826	CPVSINLSKAESQAL
T1834	KAESQALTNYGSGED
Y1836	ESQALTNYGSGEDEN
S1838	QALTNYGSGEDENED
K1885	VLQHDLEKTQESTNV
T1886	LQHDLEKTQESTNVP
T1890	LEKTQESTNVPsDQE
S1894-p	QESTNVPsDQEGTSK
T1899	VPsDQEGTSKNDQDS
S1900	PsDQEGTSKNDQDSS
K1901	sDQEGTSKNDQDSSP
S1907	SKNDQDSSPVKPCYL
Y1913	SSPVKPCYLNILENE
Y1988	SPVLVNDYEAESGNI
S1999	SGNISQKSDEEDFVK
C2017	LPLKLTVCSEAELRK
S2018	PLKLTVCSEAELRKK
S2064	PETVGAQSV______
-	gap

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