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Protein Page:
PCM-1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
PCM-1 a pericentriolar protein of unknown function. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation
Cellular Component: centrosome; pericentriolar material; nuclear membrane; protein complex; nonmotile primary cilium; cytoplasm; cytosol
Molecular Function: identical protein binding; protein binding
Biological Process: centrosome organization and biogenesis; cilium biogenesis; mitotic cell cycle; G2/M transition of mitotic cell cycle; interkinetic nuclear migration; cytoplasmic microtubule organization and biogenesis; negative regulation of neurogenesis
Reference #:  Q15154 (UniProtKB)
Alt. Names/Synonyms: hPCM-1; PCM-1; PCM1; pericentriolar material 1; Pericentriolar material 1 protein; PTC4
Gene Symbols: PCM1
Molecular weight: 228,533 Da
Basal Isoelectric point: 4.95  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

PCM-1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 K39-ub MDWGAQQkKANRSSE
0 1 K51-ub SSEKNKKkFGVEsDK
0 2 S56-p KKkFGVEsDKRVtND
0 2 T61-p VEsDKRVtNDIsPEs
0 143 S65-p KRVtNDIsPEssPGV
0 83 S68-p tNDIsPEssPGVGRR
0 72 S69-p NDIsPEssPGVGRRR
0 9 T79-p VGRRRTKtPHtFPHS
0 8 T82-p RRTKtPHtFPHSRyM
0 4 Y88-p HtFPHSRyMsQMsVP
0 6 S90-p FPHSRyMsQMsVPEQ
0 42 S93-p SRyMsQMsVPEQAEL
0 5 K102-ub PEQAELEkLkQRINF
0 2 K104-ub QAELEkLkQRINFsD
0 21 S110-p LkQRINFsDLDQRsI
0 11 S116-p FsDLDQRsIGsDsQG
0 10 S119-p LDQRsIGsDsQGRAt
0 3 S121-p QRsIGsDsQGRAtAA
0 2 T126-p sDsQGRAtAANNKRQ
0 3 K139-ub RQLSENRkPFNFLPM
0 1 K152-ub PMQINTNkSKDAsTs
0 1 S157-p TNkSKDAsTsPPNRE
0 3 S159-p kSKDAsTsPPNREtI
0 1 T165-p TsPPNREtIGsAQCk
0 1 S168-p PNREtIGsAQCkELF
0 2 K172-ub tIGsAQCkELFAsAL
0 1 S177-p QCkELFAsALsNDLL
0 2 S180-p ELFAsALsNDLLQNC
0 2 S203-p GEPAMESsQIVSRLV
0 3 Y215-p RLVQIRDyITkASSM
0 2 K218-ub QIRDyITkASSMRED
0 1 K229-ub MREDLVEkNERSANV
0 1 K255-ub EQEKSYMkFLKKILA
0 8 K259 SYMkFLKKILARDPQ
0 4 K277-ub MEEIENLkkQHDLLK
0 3 K278-ub EEIENLkkQHDLLKR
0 1 K309 ALLALQHKAEQAIAV
0 1 S320-p AIAVMDDsVVAETAG
0 1 S356-p FHNQLRDsQPPAVPD
0 2 S370-p DNRRQAEsLsLtREV
0 15 S372-p RRQAEsLsLtREVsQ
0 2 T374-p QAEsLsLtREVsQsR
0 1 S378-p LsLtREVsQsRKPsA
0 3 S380-p LtREVsQsRKPsASE
0 14 S384-p VsQsRKPsASERLPD
0 48 K393-ub SERLPDEkVELFSkM
0 1 K399-ac EkVELFSkMRVLQEK
0 5 K399-ub EkVELFSkMRVLQEK
0 1 K407-ac MRVLQEKkQkMDkLL
0 1 K409-ac VLQEKkQkMDkLLGE
0 1 K409-ub VLQEKkQkMDkLLGE
0 29 K412-ub EKkQkMDkLLGELHt
0 8 T419-p kLLGELHtLRDQHLN
0 6 S428-p RDQHLNNssssPQRs
0 4 S429-p DQHLNNssssPQRsV
0 1 S430-p QHLNNssssPQRsVD
0 9 S431-p HLNNssssPQRsVDQ
0 2 S435-p ssssPQRsVDQRSTS
0 12 K492-ub NPSEKLQkLNEVRKR
0 1 Y509-p ELRELVHyYEQTSDM
0 6 T530-p ENRKDEEtEEsEYDs
0 6 S533-p KDEEtEEsEYDsEHE
0 8 S537-p tEEsEYDsEHENsEP
0 2 S542-p YDsEHENsEPVTNIR
0 2 T556-p RNPQVAStWNEVNSH
0 1 S580-p RDGRTVNsNCEINNR
0 2 S588-p NCEINNRsAANIRAL
0 1 S634-p EAEEEGVsGASLsSH
0 1 S639-p GVsGASLsSHRSsLV
0 7 S643 ASLsSHRSsLVDEHP
0 11 S644-p SLsSHRSsLVDEHPE
0 1 K658-ub EDAEFEQkINRLMAA
0 2 Y700-p ASNLDDFyPAEEDTk
0 6 K707-ub yPAEEDTkQNSNNTR
0 2 K719 NTRGNANKtQkDtGV
0 1 T720-p TRGNANKtQkDtGVN
0 1 K722-ub GNANKtQkDtGVNEk
0 1 T724-p ANKtQkDtGVNEkAR
0 3 K729-ub kDtGVNEkAREkFyE
0 1 K733-ub VNEkAREkFyEAkLQ
0 13 Y735-p EkAREkFyEAkLQQQ
0 33 K738-ub REkFyEAkLQQQQRE
0 7 K762-ub KLIDIQEkIQALQTA
0 9 T768 EkIQALQTACPDLQL
0 5 S776-p ACPDLQLsAAsVGNC
0 1 A778 PDLQLsAAsVGNCPt
0 5 S779-p DLQLsAAsVGNCPtk
0 1 G781 QLsAAsVGNCPtkkY
0 1 N782 LsAAsVGNCPtkkYM
0 3 T785-p AsVGNCPtkkYMPAV
0 23 K786-ub sVGNCPtkkYMPAVT
0 19 K787-ub VGNCPtkkYMPAVTs
0 2 S794-p kYMPAVTstPtVNQH
0 4 T795-p YMPAVTstPtVNQHE
0 4 T797-p PAVTstPtVNQHEts
0 1 T803-p PtVNQHEtstSkSVF
0 1 S804-p tVNQHEtstSkSVFE
0 1 T805-p VNQHEtstSkSVFEP
0 1 S806 NQHEtstSkSVFEPE
0 1 K807-ub QHEtstSkSVFEPED
0 7 K841-ub EELRQRRkQLEALMA
0 3 T859-p RRQGLAEtAsPVAVs
0 1 A860 RQGLAEtAsPVAVsL
0 18 S861-p QGLAEtAsPVAVsLR
0 7 S866-p tAsPVAVsLRsDGsE
0 5 S869-p PVAVsLRsDGsENLC
0 6 S872-p VsLRsDGsENLCtPQ
0 7 T877-p DGsENLCtPQQsRTE
0 1 S881-p NLCtPQQsRTEKTMA
0 1 K954-ub KETKNRWkNNCPFsA
0 1 N955 ETKNRWkNNCPFsAD
0 45 S960-p WkNNCPFsADENyRP
0 125 Y965-p PFsADENyRPLAkTR
0 26 K970-ub ENyRPLAkTRQQNIs
0 1 T971 NyRPLAkTRQQNIsM
0 2 S977-p kTRQQNIsMQRQENL
0 5 S988-p QENLRWVsELsyVEE
0 18 S991-p LRWVsELsyVEEkEQ
0 2 Y992-p RWVsELsyVEEkEQW
0 3 K996-ub ELsyVEEkEQWQEQI
0 1 K1007-ub QEQINQLkKQLDFSV
0 10 K1076-ub QNNVQRLkQMLNELM
0 3 K1092-ub QQNQHPEkPGGkERG
0 12 K1096-ub HPEkPGGkERGSSAS
0 4 S1107-p SSASHPPsPSLFCPF
0 30 T1174-p AQNSSGKtEyMAFPk
0 220 Y1176-p NSSGKtEyMAFPkPF
0 17 K1181-ub tEyMAFPkPFEssss
0 10 S1185-p AFPkPFEssssIGAE
0 2 S1186-p FPkPFEssssIGAEk
0 12 S1187-p PkPFEssssIGAEkP
0 13 S1188-p kPFEssssIGAEkPR
0 12 K1193-ub sssIGAEkPRNkkLP
0 2 K1197-ub GAEkPRNkkLPEEEV
0 23 K1198-ub AEkPRNkkLPEEEVE
0 3 R1208 EEEVESSRtPWLyEQ
0 3 T1209-p EEVESSRtPWLyEQE
0 17 Y1213-p SSRtPWLyEQEGEVE
0 11 K1221-ub EQEGEVEkPFIkTGF
0 5 K1225-ub EVEkPFIkTGFsVsV
0 1 S1229-p PFIkTGFsVsVEKST
0 4 S1231-p IkTGFsVsVEKSTSS
0 47 S1257-p RRQFDEEsLEsFssM
0 42 S1260-p FDEEsLEsFssMPDP
0 19 S1262-p EEsLEsFssMPDPVD
0 45 S1263-p EsLEsFssMPDPVDP
0 1 K1275-ub VDPTTVTkTFKTRKA
0 8 S1283-p TFKTRKAsAQAsLAs
0 3 S1287-p RKAsAQAsLAskDKt
0 3 S1290-p sAQAsLAskDKtPKS
0 1 K1291-ub AQAsLAskDKtPKSK
0 1 T1294-p sLAskDKtPKSKSKK
0 1 T1305-p KSKKRNStQLKSRVK
0 1 K1312 tQLKSRVKNIRyEsA
0 1 Y1316-p SRVKNIRyEsASMSS
0 5 S1318-p VKNIRyEsASMSSTC
0 1 S1320 NIRyEsASMSSTCEP
0 1 S1322 RyEsASMSSTCEPCK
0 1 S1323 yEsASMSSTCEPCKS
0 1 K1329 SSTCEPCKSRNRHsA
0 1 S1335-p CKSRNRHsAQTEEPV
0 2 K1345-ub TEEPVQAkVFsRKNH
0 1 S1348-p PVQAkVFsRKNHEQL
0 1 S1373-p EISSETGsDFSMFEA
0 7 S1435-p DIVSRHIsESHEkGE
0 5 S1437 VSRHIsESHEkGENV
0 2 K1440-ub HIsESHEkGENVKSV
0 1 T1451-p VKSVNSGtWIASNSE
0 3 T1468-p PSESLATtDDETFEK
0 2 S1494 QNDADNASVLsVSSN
0 5 S1497-p ADNASVLsVSSNFEP
0 2 S1499 NASVLsVSSNFEPFA
0 1 S1500 ASVLsVSSNFEPFAT
0 4 Y1527-p ALARMREyERMktEA
0 1 K1531-ub MREyERMktEAESNS
0 5 T1532-p REyERMktEAESNSN
0 1 D1551-ca CRIIEDGdGAGAGTt
0 1 T1558-p dGAGAGTtVNNLEEt
0 9 T1565-p tVNNLEEtPVIENRS
0 2 S1573 PVIENRSSQQPVSEV
0 1 T1590-p IPCPRIDtQQLDRQI
0 2 K1602-ub RQIKAIMkEVIPFLK
0 1 K1639-ub TQQNDESkEFVKFFH
0 3 K1647-ub EFVKFFHkQLGSILQ
0 1 S1656 LGSILQDSLAkFAGR
0 2 K1659-ub ILQDSLAkFAGRKLK
0 2 S1697-p MQDLDNNsItVkQRC
0 1 T1699-p DLDNNsItVkQRCKR
0 4 K1701-ub DNNsItVkQRCKRKI
0 20 S1730-p RILEDHGsPAGEIDD
0 150 Y1757-p QTQTSEVyDGPKNVR
0 40 S1765-p DGPKNVRsDIsDQEE
0 41 S1768-p KNVRsDIsDQEEDEE
0 20 S1776-p DQEEDEEsEGCPVsI
0 1 S1782-p EsEGCPVsINLsKAE
0 1 S1786-p CPVsINLsKAETQAL
0 3 T1794-p KAETQALtNyGsGED
0 1 Y1796-p ETQALtNyGsGEDEN
0 4 S1798-p QALtNyGsGEDENED
0 1 K1845-ub VLQRDFKkTAESkNV
0 1 T1846 LQRDFKkTAESkNVP
0 1 K1850-ub FKkTAESkNVPLERE
0 2 L1854 AESkNVPLEREAtsk
0 5 T1859-p VPLEREAtskNDQNN
0 1 S1860-p PLEREAtskNDQNNC
0 1 K1861-ub LEREAtskNDQNNCP
0 1 N1866 tskNDQNNCPVKPCY
0 3 C1867 skNDQNNCPVKPCYL
0 2 Y1873 NCPVKPCYLNILEDE
0 9 Y1947-p SPVLVNDyEAESGNI
0 9 S1958-p SGNISQKsDEEDFVK
0 27 Y1976-p LPLKLTIysEADLRK
0 9 S1977-p PLKLTIysEADLRKK
0 1 S2023 PETVGAQSI______
0 1 - gap
  PCM-1 iso3  
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K53 KETKNRWKNNCPFSA
N54 ETKNRWKNNCPFSAD
S59 WKNNCPFSADENYRP
Y64 PFSADENYRPLAKTR
K69 ENYRPLAKTRQQNIS
T70 NYRPLAKTRQQNISM
S76 KTRQQNISMQRQENL
S87 QENLRWVSELSYVEE
S90 LRWVSELSYVEEKEQ
Y91 RWVSELSYVEEKEQW
K95 ELSYVEEKEQWQEQI
K106 QEQINQLKKQLDFSV
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T150-p MNRSYNVtLKRQQKA
  mouse

 
K39 MEWGGQQKKANRSSE
K51 SSEKNKKKFGVASDK
S56 KKKFGVASDKRVTNA
T61 VASDKRVTNAIsPEs
S65-p KRVTNAIsPEssPGV
S68-p TNAIsPEssPGVGRR
S69-p NAIsPEssPGVGRRR
I79 VGRRRTKIPHTFPHS
T82 RRTKIPHTFPHSRYM
Y88 HTFPHSRYMtQMsVP
T90-p FPHSRYMtQMsVPEQ
S93-p SRYMtQMsVPEQAEL
K102-ub PEQAELEkLkQRINF
K104-ub QAELEkLkQRINFsD
S110-p LkQRINFsDLDQRsI
S116-p FsDLDQRsIGsDSQG
S119-p LDQRsIGsDSQGRAT
S121 QRsIGsDSQGRATAA
T126 sDSQGRATAANNKRQ
K139-ub RQLSENRkPFNFLPM
K152 PMQINTNKSKDATAS
T157 TNKSKDATASLPKRE
S159 KSKDATASLPKREMT
M165 ASLPKREMTTSAQCK
S168 PKREMTTSAQCKELF
K172 MTTSAQCKELFASAL
S177 QCKELFASALSNDLL
S180 ELFASALSNDLLQNC
S203 GEPAMESSQIVSRLV
Y215 RLVQIRDYITKASSM
K218 QIRDYITKASSMRED
K229 MREDLVEKNERSANV
K255 EQEKSYMKFLQkILA
K259-ub SYMKFLQkILARDPQ
K277-ub MEETENLkkQHDLLK
K278-ub EETENLkkQHDLLKR
K309-ub ALLALQHkAEQAIAV
S320 AIAVMDDSVVTETTG
S356 FHNQLRDSQPPAVPD
S370 DNRRQAESLSLTREI
S372 RRQAESLSLTREISQ
T374 QAESLSLTREISQSR
S378 LSLTREISQSRNPsV
S380 LTREISQSRNPsVSE
S384-p ISQSRNPsVSEHLPD
K393-ub SEHLPDEkVQLFSkM
K399 EkVQLFSKMRVLQEK
K399-ub EkVQLFSkMRVLQEK
K407 MRVLQEKKQKMDkLL
K409 VLQEKKQKMDkLLGE
K409 VLQEKKQKMDkLLGE
K412-ub EKKQKMDkLLGELHN
N419 kLLGELHNLRDQHLN
S428 RDQHLNNSSFVPSTS
S429 DQHLNNSSFVPSTSL
T434 NSSFVPSTSLQRSGD
S435 SSFVPSTSLQRSGDK
S439 PSTSLQRSGDKRSST
K497 NPAEKLQKLNEVQKR
Y514 ELRELVHYYEQTSDM
T535 ENTKDEETEESEYDs
S538 KDEETEESEYDsEHE
S542-p TEESEYDsEHENSEP
S547 YDsEHENSEPVTNIR
T561 RNPQVASTWNEVNTN
S585 RDGRPVNSNCEINNR
S593 NCEINNRSAANIRAL
S635 EVEEEGVSGASLSSR
S640 GVSGASLSSRRssLV
S644-p ASLSSRRssLVDEAP
S645-p SLSSRRssLVDEAPE
K659 EDEEFEQKISRLMAA
Y700 ASNLDDFYAAEEDIk
K707-ub YAAEEDIkQNSNNAR
K719-ub NARENSNkIDTGVNE
I720 ARENSNkIDTGVNEk
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T722 ENSNkIDTGVNEkTR
K727-ub IDTGVNEkTREKFYE
K731 VNEkTREKFYEAkLQ
Y733 EkTREKFYEAkLQQQ
K736-ub REKFYEAkLQQQQRE
K760-ub KLIEIQEkIQAVQkA
K766-ub EkIQAVQkACPDLQL
S774-p ACPDLQLsAtsIssG
T776-p PDLQLsAtsIssGPt
S777-p DLQLsAtsIssGPtK
S779-p QLsAtsIssGPtKkY
S780-p LsAtsIssGPtKkYL
T783-p tsIssGPtKkYLPAI
K784 sIssGPtKkYLPAIT
K785-ub IssGPtKkYLPAITS
S792 kYLPAITSTPTVNEN
T793 YLPAITSTPTVNEND
T795 PAITSTPTVNENDsS
S801-p PTVNENDsStsKCVI
S802 TVNENDsStsKCVID
T803-p VNENDsStsKCVIDP
S804-p NENDsStsKCVIDPE
K805 ENDsStsKCVIDPED
K839 EELRQRRKQLEALMA
T857-p RRQGLAEtssPVAIs
S858-p RQGLAEtssPVAIsL
S859-p QGLAEtssPVAIsLR
S864-p tssPVAIsLRsDGsE
S867-p PVAIsLRsDGsENLC
S870-p IsLRsDGsENLCtPQ
T875-p DGsENLCtPQQSRTE
S879 NLCtPQQSRTEKTMA
K951 KETKTRWKsNRPVsA
S952-p ETKTRWKsNRPVsAD
S957-p WKsNRPVsADGNyRP
Y962-p PVsADGNyRPLAktR
K967-ub GNyRPLAktRQQNIS
T968-p NyRPLAktRQQNISM
S974 ktRQQNISMQRQENL
S985-p QENLRWVsELsYIEE
S988-p LRWVsELsYIEEKEQ
Y989 RWVsELsYIEEKEQW
K993 ELsYIEEKEQWQEQI
K1004 QEQINQLKKQLDFSV
K1073-ub QNNVQRLkQMLTELM
K1089-ub QQNQHPEkPRSKERG
K1093 HPEkPRSKERGSSAS
S1104 SSASHPSSPNLFCPF
T1171 AQNPSGKTEyMAFPk
Y1173-p NPSGKTEyMAFPkPF
K1178-ub TEyMAFPkPFEssss
S1182-p AFPkPFEssssLGAE
S1183-p FPkPFEssssLGAEk
S1184-p PkPFEssssLGAEkQ
S1185-p kPFEssssLGAEkQR
K1190-ub sssLGAEkQRNQKQP
Q1194 GAEkQRNQKQPEEEA
K1195 AEkQRNQKQPEEEAE
K1205-ub EEEAENTkTPWLYDQ
T1206 EEAENTkTPWLYDQE
Y1210 NTkTPWLYDQEGGVE
K1218 DQEGGVEKPFFKTGF
K1222 GVEKPFFKTGFTEsV
T1226 PFFKTGFTEsVEKAT
S1228-p FKTGFTEsVEKATNS
S1254-p RRQFDEEsLEsFssM
S1257-p FDEEsLEsFssMPDP
S1259-p EEsLEsFssMPDPID
S1260-p EsLEsFssMPDPIDP
K1272 IDPTTVTKTFKTRKA
S1280-p TFKTRKAsAQAsLAs
S1284-p RKAsAQAsLAsKDKT
S1287-p sAQAsLAsKDKTPKS
K1288 AQAsLAsKDKTPKSK
T1291 sLAsKDKTPKSKSKK
T1302 KSKKRNSTQLKSRVk
K1309-ub TQLKSRVkNIGYEsA
Y1313 SRVkNIGYEsAsVss
S1315-p VkNIGYEsAsVssTC
S1317-p NIGYEsAsVssTCEP
S1319-p GYEsAsVssTCEPCk
S1320-p YEsAsVssTCEPCkN
K1326-ub ssTCEPCkNRNRHSA
S1332 CkNRNRHSAQTEEPV
K1342 TEEPVQAKLFSRKNH
S1345 PVQAKLFSRKNHEQL
S1370 EISSETGSDFSMFEA
S1432-p DIVSRHIsEsDEREG
S1434-p VSRHIsEsDEREGEN
R1437 HIsEsDEREGENVKP
T1449 VKPVNSGTWVASNSE
T1466 PSESLVTTDDETFEK
S1492-p QNDADNVsVMsVssN
S1495-p ADNVsVMsVssNFEP
S1497-p NVsVMsVssNFEPFA
S1498-p VsVMsVssNFEPFAT
Y1525 ALARMREYERMKTET
K1529 MREYERMKTETESHS
T1530 REYERMKTETESHSN
D1549 CRVIEDEDGAAAAAT
T1556 DGAAAAATVSNSEET
T1563 TVSNSEETPIIENHN
S1571-p PIIENHNsPQPISDV
T1588 VPCPRIDTQQLDRQI
K1600 RQIKAIMKEVIPFLK
K1637 TQQNDESKEFVKFFH
K1645 EFVKFFHKQLGSILQ
S1654-p LGSILQDsLAKFAGR
K1657 ILQDsLAKFAGRKLK
S1695 MQDLDNNSIAVKQRC
A1697 DLDNNSIAVKQRCKR
K1699 DNNSIAVKQRCKRKI
S1729-p ILEGDHGsPAGEIDD
Y1756 QTQTSEVYDAKGPKN
S1766-p KGPKNVRsDVsDQEE
S1769-p KNVRsDVsDQEEDEE
S1777-p DQEEDEEsERCPVsI
S1783-p EsERCPVsINLsKAE
S1787-p CPVsINLsKAESQAL
T1795 KAESQALTNYGSGED
Y1797 ESQALTNYGSGEDEN
S1799 QALTNYGSGEDENED
K1846 ILQHDLEKtPESTNV
T1847-p LQHDLEKtPESTNVP
T1851 LEKtPESTNVPsDQE
S1855-p PESTNVPsDQEPTSK
T1860 VPsDQEPTSKNDQDs
S1861 PsDQEPTSKNDQDss
K1862 sDQEPTSKNDQDssP
S1867-p TSKNDQDssPVKPCy
S1868-p SKNDQDssPVKPCyL
Y1874-p ssPVKPCyLNILENE
Y1948-p SPVLVNDyEAESGNI
S1959-p SGNISQKsDEEDFVK
Y1977 LPLKLTVYSEEELRK
S1978 PLKLTVYSEEELRKK
S2024-p PETVGAQsI______
- gap
  rat

 
K39 MEWGGQQKKANRSSE
K51 SSEKNKKKFGVASDK
S56 KKKFGVASDKRVTND
T61 VASDKRVTNDIsPEs
S65-p KRVTNDIsPEssPGV
S68-p TNDIsPEssPGVGRR
S69-p NDIsPEssPGVGRRR
V79 VGRRRTKVPHTFPHS
T82 RRTKVPHTFPHSRYM
Y88 HTFPHSRYMTQMSVP
T90 FPHSRYMTQMSVPEQ
S93 SRYMTQMSVPEQAEL
K102 PEQAELEKLKQRINF
K104 QAELEKLKQRINFSD
S110 LKQRINFSDLDQRSI
S116 FSDLDQRSIGSDSQG
S119 LDQRSIGSDSQGRAT
S121 QRSIGSDSQGRATAA
T126 SDSQGRATAANNKRQ
K139 RQLGENRKPFNFLPM
K152 PMQINTNKSKDATAS
T157 TNKSKDATASLPKRE
S159 KSKDATASLPKRETT
T165 ASLPKRETTTSAQCK
S168 PKRETTTSAQCKELF
K172 TTTSAQCKELFASAL
S177 QCKELFASALSNDLL
S180 ELFASALSNDLLQNC
S203 GEPAMESSQIVSRLV
Y215 RLVQIRDYITKASSM
K218 QIRDYITKASSMRED
K229 MREDLVEKNERSANV
K255 EQEKSYMKFLQKILA
K259 SYMKFLQKILARDPQ
K277 MEETENLKKQHDLLK
K278 EETENLKKQHDLLKR
K309 ALLALQHKAEQAIAV
S320 AIAVMDDSVVTETTG
S356 FHNQLRDSQPPAVPD
S370 DNRRQAESLSLTREI
S372 RRQAESLSLTREISQ
T374 QAESLSLTREISQSR
S378 LSLTREISQSRNPSV
S380 LTREISQSRNPSVSE
S384 ISQSRNPSVSEHLPD
K393 SEHLPDEKVQLFSKM
K399 EKVQLFSKMRVLQEK
K399 EKVQLFSKMRVLQEK
K407 MRVLQEKKQKMDKLL
K409 VLQEKKQKMDKLLGE
K409 VLQEKKQKMDKLLGE
K412 EKKQKMDKLLGELHT
T419 KLLGELHTLRDQHLN
S428 RDQHLNNSSFVPSTS
S429 DQHLNNSSFVPSTSL
T434 NSSFVPSTSLPRSGD
S435 SSFVPSTSLPRSGDK
S439 PSTSLPRSGDKRSST
K497 NPAEKLQKLNEVQKR
Y514 ELRELVHYYEQTSDM
T535 ENTKDEETEESEYDS
S538 KDEETEESEYDSEHE
S542 TEESEYDSEHEHSEP
S547 YDSEHEHSEPVTNIR
T561 RNPQVASTWNEVNTN
S585 REGRSINSSCEINNR
S593 SCEINNRSAANIRPL
S635 EVEEEGVSGASLSSR
S640 GVSGASLSSRRSSLV
S644 ASLSSRRSSLVDEAP
S645 SLSSRRSSLVDEAPE
K659 EDEEFEQKISRLMAA
Y700 ASNLDDFYVAEEDTK
K707 YVAEEDTKQNSNNAR
K719 NARENSNKVDTGVNE
V720 ARENSNKVDTGVNEK
- gap
T722 ENSNKVDTGVNEKTR
K727 VDTGVNEKTREKFYE
K731 VNEKTREKFYEAKLQ
Y733 EKTREKFYEAKLQQQ
K736 REKFYEAKLQQQQRE
K760 KLIEIQEKIQAVQKA
K766 EKIQAVQKACPDLQL
S774 ACPDLQLSATSISSG
T776 PDLQLSATSISSGPT
S777 DLQLSATSISSGPTK
S779 QLSATSISSGPTKKY
S780 LSATSISSGPTKKYL
T783 TSISSGPTKKYLPAI
K784 SISSGPTKKYLPAIT
K785 ISSGPTKKYLPAITS
S792 KYLPAITSTPTVNEN
T793 YLPAITSTPTVNENE
T795 PAITSTPTVNENETS
T801 PTVNENETSTSKCDI
S802 TVNENETSTSKCDIE
T803 VNENETSTSKCDIEP
S804 NENETSTSKCDIEPE
K805 ENETSTSKCDIEPED
K839 EELRQRRKQLEALMA
T857 RRQGLAETASPVAVS
A858 RQGLAETASPVAVSL
S859 QGLAETASPVAVSLR
S864 TASPVAVSLRSDGSE
S867 PVAVSLRSDGSENLG
S870 VSLRSDGSENLGTPQ
T875 DGSENLGTPQQSRTE
S879 NLGTPQQSRTEKTMA
K951 KETKNRWKNHRPVSA
N952 ETKNRWKNHRPVSAD
S957 WKNHRPVSADGNYRP
Y962 PVSADGNYRPLAKTR
K967 GNYRPLAKTRQQNIS
T968 NYRPLAKTRQQNISM
S974 KTRQQNISMQRQENL
S985 QENLRWVSELSYIEE
S988 LRWVSELSYIEEKEQ
Y989 RWVSELSYIEEKEQW
K993 ELSYIEEKEQWQEQI
K1004 QEQINQLKKQLDFSV
K1073 QNNVQRLKQMLTELM
K1089 QQNQHPEKPRSKERG
K1093 HPEKPRSKERGSSAS
S1104 SSASHPSSPSLFCPF
T1171 AQNPSGKTEyMAFPK
Y1173-p NPSGKTEyMAFPKPF
K1178 TEyMAFPKPFESSSS
S1182 AFPKPFESSSSLGAE
S1183 FPKPFESSSSLGAEK
S1184 PKPFESSSSLGAEKQ
S1185 KPFESSSSLGAEKQR
K1190 SSSLGAEKQRNQKQP
Q1194 GAEKQRNQKQPEEET
K1195 AEKQRNQKQPEEETE
K1205 EEETENTKTPWLYDQ
T1206 EETENTKTPWLYDQE
Y1210 NTKTPWLYDQEGGVE
K1218 DQEGGVEKPFFKTGF
K1222 GVEKPFFKTGFAVSV
A1226 PFFKTGFAVSVEKAT
S1228 FKTGFAVSVEKATNS
S1254 GRQFDEESLESFSSM
S1257 FDEESLESFSSMPDP
S1259 EESLESFSSMPDPID
S1260 ESLESFSSMPDPIDP
K1272 IDPTTVTKTFKTRKA
S1280 TFKTRKASAQASLAS
S1284 RKASAQASLASKDKT
S1287 SAQASLASKDKTPKS
K1288 AQASLASKDKTPKSK
T1291 SLASKDKTPKSKSKK
T1302 KSKKRNSTQLKSRVK
K1309 TQLKSRVKTIGYESA
Y1313 SRVKTIGYESASVSS
S1315 VKTIGYESASVSSTC
S1317 TIGYESASVSSTCEP
S1319 GYESASVSSTCEPCK
S1320 YESASVSSTCEPCKS
K1326 SSTCEPCKSRNRHSA
S1332 CKSRNRHSAQTEEPV
K1342 TEEPVQAKLFSRKNH
S1345 PVQAKLFSRKNHEQL
S1370 EISSETGSDFSMFEA
S1432-p DIVSRHIsEsDEKEG
S1434-p VSRHIsEsDEKEGEN
K1437 HIsEsDEKEGENIKS
T1449 IKSVNSGTWVASNSE
T1466 PSESLVTTDDETFEK
S1492 QNDADNVSVMSVSSN
S1495 ADNVSVMSVSSNFEP
S1497 NVSVMSVSSNFEPFA
S1498 VSVMSVSSNFEPFAT
Y1525 ALARMREYERMKTET
K1529 MREYERMKTETESNS
T1530 REYERMKTETESNSN
D1549 CRVIEDEDGAAATTT
T1556 DGAAATTTVSNAEET
T1563 TVSNAEETPIIENHS
S1571 PIIENHSSPQPTSDV
T1588 VPCPRIDTQQLDRQI
K1600 RQIKAIMKEVIPFLK
K1637 TQQNDESKEFVKFFH
K1645 EFVKFFHKQLGSILQ
S1654 LGSILQDSLAKFAGR
K1657 ILQDSLAKFAGRKLK
S1695 MQDLDNNSIAVKQRC
A1697 DLDNNSIAVKQRCKR
K1699 DNNSIAVKQRCKRKI
S1729 ILEGDRGSPAGEIDD
Y1756 QTQTSEVYDAKGPKN
S1766-p KGPKNVRsDVsDQEE
S1769-p KNVRsDVsDQEEDEE
S1777 DQEEDEESERCPVSI
S1783 ESERCPVSINLSKAE
S1787 CPVSINLSKAESQAL
T1795 KAESQALTNYGSGED
Y1797 ESQALTNYGSGEDEN
S1799 QALTNYGSGEDENED
K1846 VLQHDLEKTQESTNV
T1847 LQHDLEKTQESTNVP
T1851 LEKTQESTNVPsDQE
S1855-p QESTNVPsDQEGTSK
T1860 VPsDQEGTSKNDQDS
S1861 PsDQEGTSKNDQDSS
K1862 sDQEGTSKNDQDSSP
S1867 TSKNDQDSSPVKPCY
S1868 SKNDQDSSPVKPCYL
Y1874 SSPVKPCYLNILENE
Y1949 SPVLVNDYEAESGNI
S1960 SGNISQKSDEEDFVK
C1978 LPLKLTVCSEAELRK
S1979 PLKLTVCSEAELRKK
S2025 PETVGAQSV______
- gap
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