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Protein Page:
53BP1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
53BP1 a DNA damage checkpoint protein that interacts with HDAC4 protein to mediate the DNA damage response. Inhibits E2F1-mediated apoptosis in prostate cancer cells. Recruited to double strand breaks via the binding of its Tudor domain to dimethylated H3 K20. Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is required for DNA binding. Binds to the central domain of p53. Interacts with Artemis. Interacts with histone H2AFX and this requires phosphorylation of H2AFX on S139. Interacts with histone H4 that has been dimethylated at K20. Has low affinity for histone H4 containing monomethylated K20. Does not bind histone H4 containing unmethylated or trimethylated K20. Has low affinity for histone H3 that has been dimethylated on K79. Does not bind unmethylated histone H3. Phosphorylated at basal level in the absence of DNA damage. Hyper-phosphorylated in an ATM-dependent manner in response to DNA damage induced by ionizing radiation. Hyper-phosphorylated in an ATR-dependent manner in response to DNA damage induced by UV irradiation. Two alternatively spliced human isoforms have been observed. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage; Transcription, coactivator/corepressor
Cellular Component: nucleoplasm; chromosome, telomeric region; cytoplasm; replication fork; nucleus
Molecular Function: protein binding; p53 binding; telomeric DNA binding; damaged DNA binding; methylated histone residue binding
Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; double-strand break repair; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; DNA repair; response to DNA damage stimulus; double-strand break repair via homologous recombination
Reference #:  Q12888 (UniProtKB)
Alt. Names/Synonyms: 53BP1; FLJ41424; MGC138366; p202; p53-binding protein 1; p53BP1; TP53B; TP53BP1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; Tumor suppressor p53-binding protein 1
Gene Symbols: TP53BP1
Molecular weight: 213,574 Da
Basal Isoelectric point: 4.62  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

53BP1

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Source  |  InnateDB  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Sites Implicated In
apoptosis, altered: S25‑p, S1778‑p
cell cycle regulation: S1219‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 0 S6-p __MDPTGsQLDSDFS
3 0 S25-p PCLIIEDsQPEsQVL
1 0 S29-p IEDsQPEsQVLEDDS
0 4 S63-p NPVLDVVsNPEQTAG
0 1 T68 VVsNPEQTAGEERGD
0 3 G76 AGEERGDGNsGFNEH
0 4 S78-p EERGDGNsGFNEHLK
0 2 G79 ERGDGNsGFNEHLKE
0 22 S105-p LDTCGSIsQVIEQLP
0 1 S119-p PQPNRTSsVLGMsVE
0 2 S124-p TSsVLGMsVESAPAV
0 1 K135-m1 APAVEEEkGEELEQK
1 0 S166-p GAEDTASsQLGFGVL
1 3 S176-p GFGVLELsQsQDVEE
1 2 S178-p GVLELsQsQDVEENT
0 3 Y188-p VEENTVPyEVDKEQL
0 3 K217-a VDANTAIkHEEQsNE
0 5 S222-p AIkHEEQsNEDIPIA
0 1 S259 QNPPPARSEDMPFsP
0 9 F264 ARSEDMPFsPKASVA
0 33 S265-p RSEDMPFsPKASVAA
0 2 S287-p SAQELMEsGLQIQKs
1 17 S294-p sGLQIQKsPEPEVLs
0 1 S301-p sPEPEVLstQEDLFD
1 13 T302-p PEPEVLstQEDLFDQ
0 2 T313-p LFDQSNKtVssDGCs
0 2 S315-p DQSNKtVssDGCstP
0 5 S316-p QSNKtVssDGCstPs
0 4 S320-p tVssDGCstPsREEG
0 11 T321-p VssDGCstPsREEGG
0 6 S323-p sDGCstPsREEGGCS
0 2 T334-p GGCSLAStPATTLHL
0 2 S349-p LQLSGQRsLVQDSLS
0 27 S366-p SSDLVAPsPDAFRST
0 7 S379-p STPFIVPssPtEQEG
2 31 S380-p TPFIVPssPtEQEGR
0 6 T382-p FIVPssPtEQEGRQD
0 4 S395-p QDKPMDTsVLsEEGG
0 8 S398-p PMDTsVLsEEGGEPF
0 1 T427 PPLLPESTVSPQAST
0 6 S429 LLPESTVSPQASTPI
1 1 S452-p PGSLPIPsQPQFSHD
0 4 S464 SHDIFIPSPSLEEQS
0 1 S466 DIFIPSPSLEEQSND
0 19 S500-p SEIEPKNsPEDLGLs
0 2 S507-p sPEDLGLsLTGDSCK
0 1 T509 EDLGLsLTGDSCKLM
0 1 S512 GLsLTGDSCKLMLst
0 2 S518-p DSCKLMLstsEysQs
0 2 T519-p SCKLMLstsEysQsP
0 1 S520-p CKLMLstsEysQsPk
0 6 Y522-p LMLstsEysQsPkME
1 25 S523-p MLstsEysQsPkMEs
0 20 S525-p stsEysQsPkMEsLS
0 1 K527-u sEysQsPkMEsLSsH
0 4 S530-p sQsPkMEsLSsHRID
0 17 S533-p PkMEsLSsHRIDEDG
0 1 I536 EsLSsHRIDEDGENt
0 49 T543-p IDEDGENtQIEDtEP
0 12 T548-p ENtQIEDtEPMsPVL
1 87 S552-p IEDtEPMsPVLNsKF
0 1 L555 tEPMsPVLNsKFVPA
0 1 S557-p PMsPVLNsKFVPAEN
0 7 S566-p FVPAENDsILMNPAQ
0 31 S580-p QDGEVQLsQNDDKtK
0 2 T586-p LsQNDDKtKGDDtDt
0 1 T591-p DKtKGDDtDtRDDIS
0 1 T593-p tKGDDtDtRDDISIL
0 1 S625-p DLTCDSGsQAVPsPA
0 1 S630-p SGsQAVPsPATRsEA
0 9 S635-p VPsPATRsEALssVL
0 12 S639-p ATRsEALssVLDQEE
0 12 S640-p TRsEALssVLDQEEA
0 1 S659-p EHHPEEGssGsEVEE
0 6 S660-p HHPEEGssGsEVEEI
0 5 S662-p PEEGssGsEVEEIPE
0 1 S674 IPETPCESQGEELKE
0 3 T696-p LHLSLTEtQsQGLCL
0 4 S698-p LSLTEtQsQGLCLQK
0 1 S724-p EVETSVIsIDsPQKL
0 6 S727-p TSVIsIDsPQKLAIL
0 1 T750-p QEAWEEAtsEDssVV
0 1 S751-p EAWEEAtsEDssVVI
0 1 S754-p EEAtsEDssVVIVDV
0 1 S755-p EAtsEDssVVIVDVK
0 11 S771-p PSPRVDVsCEPLEGV
0 4 S782-p LEGVEKCsDsQsWED
1 7 S784-p GVEKCsDsQsWEDIA
0 4 S786-p EKCsDsQsWEDIAPE
0 3 T804-p CAENRLDtKEEKsVE
0 6 S809-p LDtKEEKsVEYEGDL
0 1 D829-ca ETEPVEQdssQPsLP
0 12 S830-p TEPVEQdssQPsLPL
1 12 S831-p EPVEQdssQPsLPLV
0 3 S834-p EQdssQPsLPLVRAD
0 43 T855-p QELQQPQtQEKtsNs
0 6 T859-p QPQtQEKtsNsLTED
0 7 S860-p PQtQEKtsNsLTEDS
0 15 S862-p tQEKtsNsLTEDSKM
0 3 S876-p MANAKQLssDAEAQK
0 4 S877-p ANAKQLssDAEAQKL
0 7 S892-p GKPSAHAsQsFCESS
0 3 S894-p PSAHAsQsFCESSSE
0 6 T922-p IPPLTGAtPPLIGHL
0 3 T938-p LEPKRHStPIGISNY
0 1 S970-p THDPILGsGKGDsGA
0 3 S975-p LGsGKGDsGAAPDVD
0 6 S993-p CLRMKLVsPEtEAsE
0 1 T996-p MKLVsPEtEAsEEsL
0 4 S999-p VsPEtEAsEEsLQFN
0 4 S1002-p EtEAsEEsLQFNLEK
0 1 S1019 TGERKNGSTAVAEsV
0 3 S1025-p GSTAVAEsVAsPQKT
1 18 S1028-p AVAEsVAsPQKTMSV
0 2 T1055-p ARSEDPPttPIRGNL
0 20 T1056-p RSEDPPttPIRGNLL
0 14 S1067-p GNLLHFPssQGEEEK
0 24 S1068-p NLLHFPssQGEEEKE
1 9 S1086-p GDHTIRQsQQPMKPI
0 110 S1094-p QQPMKPIsPVKDPVs
0 1 - gap
0 116 S1101-p sPVKDPVsPAsQKMV
0 52 S1104-p KDPVsPAsQKMVIQG
0 5 - gap
0 1 - gap
0 5 S1113-p KMVIQGPssPQGEAM
1 29 S1114-p MVIQGPssPQGEAMV
0 5 S1148-p KALIERPsQNNIGIQ
0 1 R1162-m1 QTMECSLrVPETVSA
0 1 T1171-p PETVSAAtQTIkNVC
0 1 K1175-m1 SAAtQTIkNVCEQGT
0 3 S1208-p GSGEKPVsAPGDDtE
0 14 T1214-p VsAPGDDtEsLHsQG
0 16 S1216-p APGDDtEsLHsQGEE
3 18 S1219-p DDtEsLHsQGEEEFD
1 0 K1268 DGTEVERKVTEETEE
0 3 S1290-p CETEVSPsQTGGSSG
0 8 T1315-p KASSLHRtssGtsLS
0 10 S1316-p ASSLHRtssGtsLSA
0 21 S1317-p SSLHRtssGtsLSAM
0 8 T1319-p LHRtssGtsLSAMHS
0 12 S1320-p HRtssGtsLSAMHSS
0 22 K1332-a HSSGSSGkGAGPLRG
0 1 K1332 HSSGSSGKGAGPLRG
0 3 S1342-p GPLRGKTsGTEPADF
0 1 R1355 DFALPSSRGGPGKLs
0 26 S1362-p RGGPGKLsPRKGVsQ
0 9 S1368-p LsPRKGVsQTGtPVC
0 3 T1372-p KGVsQTGtPVCEEDG
2 0 R1396-m GKAPVTPrGrGrrGr
2 0 R1398-m APVTPrGrGrrGrPP
2 0 R1400-m VTPrGrGrrGrPPSR
2 0 R1401-m TPrGrGrrGrPPSRT
2 0 R1403-m rGrGrrGrPPSRTTG
0 14 S1426-p PLGIEDIsPNLsPDD
0 1 N1428 GIEDIsPNLsPDDKs
0 19 S1430-p EDIsPNLsPDDKsFS
0 1 S1435-p NLsPDDKsFSRVVPR
0 1 T1450-p VPDSTRRtDVGAGAL
0 4 S1460-p GAGALRRsDsPEIPF
0 16 S1462-p GALRRsDsPEIPFQA
0 1 A1471 EIPFQAAAGPsDGLD
0 1 P1473 PFQAAAGPsDGLDAs
0 1 S1474-p FQAAAGPsDGLDAss
0 1 S1480-p PsDGLDAssPGNSFV
0 3 S1481-p sDGLDAssPGNSFVG
1 1 Y1500-p AKWSSNGyFYSGKIT
1 4 Y1523-p KLLFDDGyECDVLGK
0 14 Y1552-p TALSEDEyFSAGVVK
0 11 Y1605-p EQYGLGPyEAVtPLt
1 13 T1609-p LGPyEAVtPLtKAAD
1 1 T1612-p yEAVtPLtKAADIsL
0 9 S1618-p LtKAADIsLDNLVEG
0 3 K1626-a LDNLVEGkRKRRsNV
0 1 K1626-m1 LDNLVEGkRKRRsNV
0 5 S1631-p EGkRKRRsNVssPAt
0 5 S1634-p RKRRsNVssPAtPtA
0 5 S1635-p KRRsNVssPAtPtAs
0 14 T1638-p sNVssPAtPtAssss
0 4 T1640-p VssPAtPtAssssst
0 2 S1642-p sPAtPtAsssssttP
0 1 S1643-p PAtPtAsssssttPT
0 2 S1644-p AtPtAsssssttPTR
0 1 S1645-p tPtAsssssttPTRK
0 2 S1646-p PtAsssssttPTRKI
0 3 T1647-p tAsssssttPTRKIt
0 14 T1648-p AsssssttPTRKItE
0 1 T1654-p ttPTRKItEsPRASM
0 4 S1656-p PTRKItEsPRASMGV
0 3 S1665-p RASMGVLsGkRKLIt
0 16 K1667-a SMGVLsGkRKLItsE
0 1 T1672-p sGkRKLItsEEERsP
0 6 S1673-p GkRKLItsEEERsPA
1 14 S1678-p ItsEEERsPAKRGRK
0 5 S1701-p VGAGEFVsPCEsGDN
0 2 S1705-p EFVsPCEsGDNTGEP
0 1 S1749-p SDKLASRsKLPDGPt
0 2 T1756-p sKLPDGPtGssEEEE
0 6 S1758-p LPDGPtGssEEEEEF
0 7 S1759-p PDGPtGssEEEEEFL
4 1 S1778-p FNKQYTEsQLRAGAG
2674 : Phospho-53BP1 (Ser25/29) Antibody
2674 : Phospho-53BP1 (Ser25/29) Antibody
3428 : Phospho-53BP1 (Thr543) Antibody
6209 : Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb
2675 : Phospho-53BP1 (Ser1778) Antibody
  mouse

 
S6 __MDPTGSQLDSDFS
S25 PCLIIEDSQPESQVL
S29 IEDSQPESQVLEEDA
S63-p NPVLDIVsNPEQsAV
S68-p IVsNPEQsAVEQGDs
S75-p sAVEQGDsNssFNEH
S77-p VEQGDsNssFNEHLK
S78-p EQGDsNssFNEHLKE
S104 LGTSGSISQVIERLP
S118 PQPNRTSSALAVTVE
T123 TSSALAVTVEAASLP
K134 ASLPEEEKEEEELEE
S163 AAEDSASSQLGFGVL
S173 GFGVLELSQSQDVEE
S175 GVLELSQSQDVEEHT
Y185 VEEHTVPYDVNQEHL
K214 VDASTAIKCEEQPTE
P219 AIKCEEQPTEDIAMI
S256-p QNLPLVRsEDRPssP
S261-p VRsEDRPssPQVSVA
S262-p RsEDRPssPQVSVAA
E284 PARELLEEGPQVQPS
S291 EGPQVQPSSEPEVSS
S298 SSEPEVSSTQEDLFD
T299 SEPEVSSTQEDLFDQ
T310 LFDQSSKTASDGCSt
S312 DQSSKTASDGCStPs
- gap
S316 KTASDGCStPsREEG
T317-p TASDGCStPsREEGG
S319-p SDGCStPsREEGGCS
T330 GGCSPVSTPATTLQL
P345 LQLSGQKPLVQESLS
S362-p SSDLVAPsPDAFRST
S375-p STPFIVPssPtEQGG
S376-p TPFIVPssPtEQGGR
T378-p FIVPssPtEQGGRKD
S391 KDEPMDMSVIPAGGE
P394 PMDMSVIPAGGEPFQ
T421-p PLLPSQPtVsPQAST
S423-p LPSQPtVsPQASTPV
S446-p PGSLPIPsQPEFSHD
S458-p SHDIFIPsPsLEEPS
S460-p DIFIPsPsLEEPSDD
F494 SESEPKNFTDDLGLS
S501 FTDDLGLSMtGDsCK
T503-p DDLGLSMtGDsCKLM
S506-p GLSMtGDsCKLMLst
S512-p DsCKLMLstSEYSQS
T513-p sCKLMLstSEYSQSS
S514 CKLMLstSEYSQSSK
Y516 LMLstSEYSQSSKME
S517 MLstSEYSQSSKMEs
S519 stSEYSQSSKMEsLG
K521 SEYSQSSKMEsLGsP
S524-p SQSSKMEsLGsPRtE
S527-p SKMEsLGsPRtEEDR
T530-p EsLGsPRtEEDRENt
T537-p tEEDRENtQIDDtEP
T542-p ENtQIDDtEPLsPVs
S546-p IDDtEPLsPVsNsKL
S549-p tEPLsPVsNsKLPAD
S551-p PLsPVsNsKLPADSE
N559 KLPADSENVLVTPSQ
S573 QDDQVEMSQNVDKAK
- gap
T584 DKAKEDETEDRGDCK
- gap
S611 DLTCDSGSQAVPsPA
S616-p SGSQAVPsPATRsEA
S621-p VPsPATRsEALssVL
S625-p ATRsEALssVLDQEE
S626-p TRsEALssVLDQEEA
- gap
S646-p HHPEEGFsGsEVEEV
S648-p PEEGFsGsEVEEVPE
S660-p VPETPCGsHREEPKE
T682 LHLSLTETQSEALCL
S684 LSLTETQSEALCLQK
S710-p EVETSVIsIDsPQKL
S713-p TSVIsIDsPQKLQVL
T736 PDTWEEATSEDSSVV
S737 DTWEEATSEDSSVVI
S740 EEATSEDSSVVIVDV
S741 EATSEDSSVVIVDVK
S757-p PSPRADVsCEPLEEV
S768-p LEEVEKCsDsQsWEG
S770-p EVEKCsDsQsWEGVA
S772-p EKCsDsQsWEGVAPE
T790-p CAENRLDtPEEKRIE
- gap
D815 EKDAVTEDsPQPPLP
S816-p KDAVTEDsPQPPLPS
- gap
- gap
- gap
- gap
S845 PQVQEKESPVTVDAE
- gap
- gap
- gap
S876-p EKAPACAsQsFCESS
S878-p APACAsQsFCESSSE
T906-p IPPLTGAtPPLIGHL
T922 LEPKRHSTPIGISNY
N954 INDPLLGNEKGDSES
S959 LGNEKGDSESAPEMD
S977-p SLKMKLVsPETEASE
T980 MKLVsPETEASEESL
S983 VsPETEASEESLQFS
S986 ETEASEESLQFSLEK
S1003 TAERKNGSTAIAEPV
- gap
S1012 AIAEPVASLQKPVPV
S1039 AQSEAPPSAPDRANL
- gap
S1051 ANLLHFPSAQEEDKE
- gap
S1069 VTPKLRQSEQPVKPV
- gap
S1088-p DDAAPEDsAsPVsQQ
S1090-p AAPEDsAsPVsQQRA
S1093-p EDsAsPVsQQRAsQE
S1098-p PVsQQRAsQEPFsPA
- gap
- gap
S1103-p RAsQEPFsPAEDVME
T1133 KMLMDRPTQSNIGIQ
- gap
T1156 PETVSAATQTVKSVC
K1160 SAATQTVKSVCEQGT
S1193-p GSGEKPAsAPVDDtE
T1199-p AsAPVDDtEsLHsQG
S1201-p APVDDtEsLHsQGEE
S1204-p DDtEsLHsQGEEEFE
K1253-u DGTEVERkVTEETEE
S1275 CETEVSPSQTGGSSG
T1300 KASSSHHTSSGTSLS
S1301 ASSSHHTSSGTSLSA
S1302 SSSHHTSSGTSLSAI
T1304 SHHTSSGTSLSAIHS
S1305 HHTSSGTSLSAIHSS
R1317 HSSGSSGRGAGPLKG
R1317-m1 HSSGSSGrGAGPLKG
S1327 GPLKGKASGTEAADF
R1340-m1 DFALPSSrGGPGKLs
S1347-p rGGPGKLsPRKGISQ
S1353 LsPRKGISQTGAPVC
- gap
R1381 GKAPVTPRGRGRRGR
R1383 APVTPRGRGRRGRPP
R1385 VTPRGRGRRGRPPSR
R1386 TPRGRGRRGRPPSRT
R1388 RGRGRRGRPPSRTTG
S1411-p PLGVEDIsPsMsPDD
S1413-p GVEDIsPsMsPDDKs
S1415-p EDIsPsMsPDDKsFT
S1420-p sMsPDDKsFTRIMPR
T1435 VPDSTKRTDASSSTL
S1445-p SSSTLRRsDsPEIPF
S1447-p STLRRsDsPEIPFQA
T1456-p EIPFQAAtGssDGLD
S1458-p PFQAAtGssDGLDSS
S1459-p FQAAtGssDGLDSSS
S1465 ssDGLDSSSSGNSFV
S1466 sDGLDSSSSGNSFVG
Y1485 AKWSSNGYFYSGKIT
Y1508 KLLFDDGYECDVLGK
Y1537 TALSEDEYFSAGVVK
Y1590 EQYGLGPYEAVTPLT
T1594 LGPYEAVTPLTKAAD
T1597 YEAVTPLTKAADIsL
S1603-p LTKAADIsLDNLVEG
K1611 LDNLVEGKRKRRsNI
K1611 LDNLVEGKRKRRsNI
S1616-p EGKRKRRsNIssPVT
S1619-p RKRRsNIssPVTPTA
S1620-p KRRsNIssPVTPTAA
T1623 sNIssPVTPTAASsS
T1625 IssPVTPTAASsSST
- gap
S1628 PVTPTAASsSSTtPT
S1629-p VTPTAASsSSTtPTR
S1630 TPTAASsSSTtPTRK
S1631 PTAASsSSTtPTRKA
T1632 TAASsSSTtPTRKAT
T1633-p AASsSSTtPTRKATE
T1639 TtPTRKATEsPRAST
S1641-p PTRKATEsPRASTGV
S1650 RASTGVPSGKRKLPT
K1652 STGVPSGKRKLPTSE
T1657 SGKRKLPTSEEERsP
S1658 GKRKLPTSEEERsPA
S1663-p PTSEEERsPAKRGRK
S1686 VGAAEFVSPCETGDN
T1690 EFVSPCETGDNIGEP
S1734 SDKLASRSKLLDGPT
T1741 SKLLDGPTGssEEEE
S1743-p LLDGPTGssEEEEEF
S1744-p LDGPTGssEEEEEFL
- gap
6209 : Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb
  rat

 
S11 EQMDPTGSQLDSDFS
S30 PCLIIEDSQPESQAL
S34 IEDSQPESQALEEDA
S68 NPVLDIMSNPEQTVA
T73 IMSNPEQTVAEQGDS
S80 TVAEQGDSNSSFSEH
S82 AEQGDSNSSFSEHLK
S83 EQGDSNSSFSEHLKE
S109 LGTSGPISQVIERLP
S123 PQPNRTSSALGVTVE
T128 TSSALGVTVEAASLA
K139 ASLAEEEKEEELEEE
S169 LAEDSASSQLGFGVL
S179-p GFGVLELsQSQDVEE
S181 GVLELsQSQDVEEHT
Y191 VEEHTVPYDVKQEHL
K223 NTDGKAIKCEEQSTD
S228 AIKCEEQSTDAISII
S264 QNLPLVRSEDLPSsP
S269 VRSEDLPSsPQVSVA
S270-p RSEDLPSsPQVSVAA
G292 PAQELLEGGLQVQVS
S299 GGLQVQVSSEPEVSS
S306 SSEPEVSSTQEDLFD
T307 SEPEVSSTQEDLFDQ
T318 LFDQSSKTASDGCST
S320 DQSSKTASDGCSTPS
- gap
S324 KTASDGCSTPSREEG
T325 TASDGCSTPSREEGG
S327 SDGCSTPSREEGGCS
T338 GGCSPVSTPATTLQL
P353 LQLSGQKPLVQESLS
S370 SSDLVAPSPDAFRST
S383 STPFIVPSsPTEQGQ
S384-p TPFIVPSsPTEQGQR
T386 FIVPSsPTEQGQRKD
S399 KDEPMDMSVIPEGGE
P402 PMDMSVIPEGGEHFQ
A429 PLLPSQPAVsPQAST
S431-p LPSQPAVsPQASTPV
S454 PASLPIPSQPEFSHD
S466-p SHDIFIPsPSLEEPS
S468 DIFIPsPSLEEPSND
F502 SESEPKNFTDDLGLS
S509 FTDDLGLSMTGDSCK
T511 DDLGLSMTGDSCKLM
S514 GLSMTGDSCKLMLST
S520 DSCKLMLSTSECSQS
T521 SCKLMLSTSECSQSS
S522 CKLMLSTSECSQSSK
C524 LMLSTSECSQSSKME
S525 MLSTSECSQSSKMEs
S527 STSECSQSSKMEsLG
K529 SECSQSSKMEsLGsP
S532-p SQSSKMEsLGsPRTE
S535-p SKMEsLGsPRTEEVG
T538 EsLGsPRTEEVGENT
T545 TEEVGENTQVEDTEP
T550 ENTQVEDTEPSsPVt
S554-p VEDTEPSsPVtKSKL
T557-p TEPSsPVtKSKLPAE
S559 PSsPVtKSKLPAESE
S567 KLPAESESVLVNPTQ
S581 QDDQVEMSQNVDKAK
- gap
- gap
- gap
S626 DLTCDSGSQAVPSPA
S631 SGSQAVPSPATRSEA
S636 VPSPATRSEALssVL
S640-p ATRSEALssVLDQEE
S641-p TRSEALssVLDQEEA
- gap
S661 HHPEEEFSGSEVEEV
S663 PEEEFSGSEVEEVPE
S675 VPETPCGSHREESKE
T697 LHLSLTETQSEALCL
S699 LSLTETQSEALCLQK
S725 EVETSVISIDSPQKL
S728 TSVISIDSPQKLPVL
T751 PETWEEATSEDSSVV
S752 ETWEEATSEDSSVVI
S755 EEATSEDSSVVIVDV
S756 EATSEDSSVVIVDVK
S772 PSPRVDISCEPVEGV
S783 VEGVGKCSDSQSLEG
S785 GVGKCSDSQSLEGAA
S787 GKCSDSQSLEGAAPE
T805-p CAENRLNtPEEKRVE
- gap
D830 EKNSVTEDsPQPPLP
S831-p KNSVTEDsPQPPLPS
- gap
- gap
- gap
- gap
S860-p PQVQEKEsPVTLDAK
- gap
- gap
S876 ADDKHLGSEGSCQQL
S891 EKAPARASQSFCESS
S893 APARASQSFCESSSE
T921 IPPLTGATPPLIGHL
T937 LEPKRHSTPIGISNY
N969 INDPLLGNEKGDSES
S974 LGNEKGDSESAPEMD
S992-p SLKMKLVsPETEASE
T995 MKLVsPETEASEESL
S998 VsPETEASEESLQFS
S1001 ETEASEESLQFSLEK
S1018-p TAERRNGsTAIAEPV
- gap
S1027 AIAEPVASPQKPMSV
S1054 AQSGDPPStPVRTNL
T1055-p QSGDPPStPVRTNLL
S1066 TNLLHFPSAQEEDRE
- gap
S1084 ATPQLRQSEQPVKLI
- gap
S1103 DAAASEDSASSVSQQ
S1105 AASEDSASSVSQQRA
S1108 EDSASSVSQQRAsQG
S1113-p SVSQQRAsQGsLsPQ
S1116-p QQRAsQGsLsPQEEV
- gap
S1118-p RAsQGsLsPQEEVME
T1148 KILMERPTQSNIGIQ
- gap
T1171 PETVSAATQTVKNVC
K1175 SAATQTVKNVCEQGT
S1208 GSGEKPASAPVDDTE
T1214 ASAPVDDTESLHSQG
S1216 APVDDTESLHSQGEE
S1219 DDTESLHSQGEEEFE
K1268 DGTEVERKVTEETEE
S1290 CETEVSPSQTGGSSG
T1315 KASSSHHTSSGTSLS
S1316 ASSSHHTSSGTSLSA
S1317 SSSHHTSSGTSLSAI
T1319 SHHTSSGTSLSAIHS
S1320 HHTSSGTSLSAIHSS
R1332 HSSGSSGRGAGPLKG
R1332 HSSGSSGRGAGPLKG
S1342 GPLKGKTSGTEPADF
R1355 DFALPSSRGGPGKLs
S1362-p RGGPGKLsPRKGISQ
S1368 LsPRKGISQTGAPVC
- gap
R1396 GKAPVTPRGRGRRGR
R1398 APVTPRGRGRRGRPP
R1400 VTPRGRGRRGRPPSR
R1401 TPRGRGRRGRPPSRT
R1403 RGRGRRGRPPSRTTG
S1426 PLGIEDTSPSMSPDD
S1428 GIEDTSPSMSPDDKS
S1430 EDTSPSMSPDDKSFT
S1435 SMSPDDKSFTRIMPR
M1450 VPDSTKRMDASSGAL
S1460 SSGALRRSDSPEIPF
S1462 GALRRSDSPEIPFQA
T1471 EIPFQAATGSSDGLD
S1473 PFQAATGSSDGLDSS
S1474 FQAATGSSDGLDSSS
S1480 SSDGLDSSSSGNSFV
S1481 SDGLDSSSSGNSFVG
Y1500 AKWSSNGYFYSGKIT
Y1523 KLLFDDGYECDVLGK
Y1552 TALSEDEYFSAGVVK
Y1605 EQYGLGPYEAVTPLT
T1609 LGPYEAVTPLTKAAD
T1612 YEAVTPLTKAADISL
S1618 LTKAADISLDNLVEG
K1626 LDNLVEGKRKRRSNI
K1626 LDNLVEGKRKRRSNI
S1631 EGKRKRRSNISSPAT
S1634 RKRRSNISSPATPtA
S1635 KRRSNISSPATPtAs
T1638 SNISSPATPtAsSSS
T1640-p ISSPATPtAsSSSSt
S1642-p SPATPtAsSSSStTP
S1643 PATPtAsSSSStTPT
S1644 ATPtAsSSSStTPTR
S1645 TPtAsSSSStTPTRK
S1646 PtAsSSSStTPTRKT
T1647-p tAsSSSStTPTRKTT
T1648 AsSSSStTPTRKTTE
T1654 tTPTRKTTESPRASM
S1656 PTRKTTESPRASMGV
S1665 RASMGVPSGKRKLTT
K1667 SMGVPSGKRKLTTSE
T1672 SGKRKLTTSEEERsP
S1673 GKRKLTTSEEERsPA
S1678-p TTSEEERsPAKRGRK
S1701-p VGAAELVsPCESGDN
S1705 ELVsPCESGDNTGEP
S1749 SDKLASRSKLLDGPT
T1756 SKLLDGPTGSSEEEE
S1758 LLDGPTGSSEEEEEF
S1759 LDGPTGSSEEEEEFL
- gap
6209 : Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb
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