Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
53BP1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
53BP1 a DNA damage checkpoint protein that interacts with HDAC4 protein to mediate the DNA damage response. Inhibits E2F1-mediated apoptosis in prostate cancer cells. Recruited to double strand breaks via the binding of its Tudor domain to dimethylated H3 K20. Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is required for DNA binding. Binds to the central domain of p53. Interacts with Artemis. Interacts with histone H2AFX and this requires phosphorylation of H2AFX on S139. Interacts with histone H4 that has been dimethylated at K20. Has low affinity for histone H4 containing monomethylated K20. Does not bind histone H4 containing unmethylated or trimethylated K20. Has low affinity for histone H3 that has been dimethylated on K79. Does not bind unmethylated histone H3. Phosphorylated at basal level in the absence of DNA damage. Hyper-phosphorylated in an ATM-dependent manner in response to DNA damage induced by ionizing radiation. Hyper-phosphorylated in an ATR-dependent manner in response to DNA damage induced by UV irradiation. Two alternatively spliced human isoforms have been observed. Note: This description may include information from UniProtKB.
Protein type: Transcription, coactivator/corepressor; DNA repair, damage
Cellular Component: nucleoplasm; chromosome, telomeric region; cytoplasm; replication fork; nucleus
Molecular Function: protein binding; p53 binding; telomeric DNA binding; damaged DNA binding; methylated histone residue binding
Biological Process: transcription from RNA polymerase II promoter; double-strand break repair; positive regulation of transcription, DNA-dependent; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; DNA repair; response to DNA damage stimulus; double-strand break repair via homologous recombination
Reference #:  Q12888 (UniProtKB)
Alt. Names/Synonyms: 53BP1; FLJ41424; MGC138366; p202; p53-binding protein 1; p53BP1; TP53B; TP53BP1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; Tumor suppressor p53-binding protein 1
Gene Symbols: TP53BP1
Molecular weight: 213,574 Da
Basal Isoelectric point: 4.62  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

53BP1

Protein Structure Not Found.


STRING  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  InnateDB


Sites Implicated In
apoptosis, altered: S25‑p, S1778‑p
cell cycle regulation: S1219‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 0 S6-p __MDPTGsQLDSDFS
3 0 S25-p PCLIIEDsQPEsQVL
1 0 S29-p IEDsQPEsQVLEDDS
0 1 K54-ac LPNLQTHkENPVLDV
0 4 S63-p NPVLDVVsNPEQTAG
0 1 T68 VVsNPEQTAGEERGD
0 3 G76 AGEERGDGNsGFNEH
0 5 S78-p EERGDGNsGFNEHLK
0 2 G79 ERGDGNsGFNEHLKE
0 1 T100-p VDSSNLDtCGsIsQV
0 1 S103-p SNLDtCGsIsQVIEQ
0 23 S105-p LDtCGsIsQVIEQLP
0 1 T117-p QLPQPNRtSsVLGMs
0 1 S119-p PQPNRtSsVLGMsVE
0 3 S124-p tSsVLGMsVEsAPAV
0 1 S127-p VLGMsVEsAPAVEEE
0 1 K135-m1 APAVEEEkGEELEQK
1 0 S166-p GAEDTASsQLGFGVL
1 3 S176-p GFGVLELsQsQDVEE
1 2 S178-p GVLELsQsQDVEENT
0 3 Y188-p VEENTVPyEVDKEQL
0 1 S208-p NSGYTRLsDVDANTA
0 3 K217-ac VDANTAIkHEEQsNE
0 6 S222-p AIkHEEQsNEDIPIA
0 1 K244-ac PVTAQPSkDVHVVKE
0 1 S259-p QNPPPARsEDMPFsP
0 10 F264 ARsEDMPFsPKASVA
0 35 S265-p RsEDMPFsPKASVAA
0 1 A275 ASVAAMEAKEQLSAQ
0 2 S287-p SAQELMEsGLQIQKs
1 19 S294-p sGLQIQKsPEPEVLs
0 1 S301-p sPEPEVLstQEDLFD
1 13 T302-p PEPEVLstQEDLFDQ
0 2 T313-p LFDQSNKtVssDGCs
0 2 S315-p DQSNKtVssDGCstP
0 6 S316-p QSNKtVssDGCstPs
0 4 S320-p tVssDGCstPsREEG
0 12 T321-p VssDGCstPsREEGG
0 6 S323-p sDGCstPsREEGGCS
0 2 T334-p GGCSLAStPAtTLHL
0 1 T337-p SLAStPAtTLHLLQL
0 2 S349-p LQLSGQRsLVQDSLS
0 27 S366-p SSDLVAPsPDAFRSt
0 1 T373-p sPDAFRStPFIVPss
0 10 S379-p StPFIVPssPtEQEG
2 33 S380-p tPFIVPssPtEQEGR
0 7 T382-p FIVPssPtEQEGRQD
0 1 T394-p RQDKPMDtsVLsEEG
0 6 S395-p QDKPMDtsVLsEEGG
0 11 S398-p PMDtsVLsEEGGEPF
0 1 T427 PPLLPESTVSPQAST
0 7 S429 LLPESTVSPQASTPI
1 2 S452-p PGSLPIPsQPQFSHD
0 5 S464 SHDIFIPSPSLEEQS
0 1 S466 DIFIPSPSLEEQSND
0 22 S500-p SEIEPKNsPEDLGLs
0 2 S507-p sPEDLGLsLTGDSCK
0 1 T509 EDLGLsLTGDSCKLM
0 1 S512 GLsLTGDSCKLMLst
0 3 S518-p DSCKLMLstsEysQs
0 2 T519-p SCKLMLstsEysQsP
0 2 S520-p CKLMLstsEysQsPk
0 6 Y522-p LMLstsEysQsPkME
1 31 S523-p MLstsEysQsPkMEs
0 23 S525-p stsEysQsPkMEsLs
0 1 K527-ac sEysQsPkMEsLssH
0 1 K527-ub sEysQsPkMEsLssH
0 6 S530-p sQsPkMEsLssHRID
0 2 S532-p sPkMEsLssHRIDED
0 18 S533-p PkMEsLssHRIDEDG
0 1 I536 EsLssHRIDEDGENt
0 52 T543-p IDEDGENtQIEDtEP
0 13 T548-p ENtQIEDtEPMsPVL
1 95 S552-p IEDtEPMsPVLNsKF
0 1 L555 tEPMsPVLNsKFVPA
0 4 S557-p PMsPVLNsKFVPAEN
0 8 S566-p FVPAENDsILMNPAQ
0 33 S580-p QDGEVQLsQNDDKtK
0 3 T586-p LsQNDDKtKGDDtDt
0 2 T591-p DKtKGDDtDtRDDIs
0 2 T593-p tKGDDtDtRDDIsIL
0 1 S598-p tDtRDDIsILATGCK
0 1 S625-p DLTCDSGsQAVPsPA
0 2 S630-p SGsQAVPsPATRsEA
0 10 S635-p VPsPATRsEALssVL
0 14 S639-p ATRsEALssVLDQEE
0 14 S640-p TRsEALssVLDQEEA
0 1 S659-p EHHPEEGssGsEVEE
0 6 S660-p HHPEEGssGsEVEEI
0 5 S662-p PEEGssGsEVEEIPE
0 1 S674 IPETPCESQGEELKE
0 1 S686-p LKEENMEsVPLHLsL
0 1 S692-p EsVPLHLsLTEtQsQ
0 3 T696-p LHLsLTEtQsQGLCL
0 4 S698-p LsLTEtQsQGLCLQK
0 3 S724-p EVETSVIsIDsPQKL
0 8 S727-p TSVIsIDsPQKLAIL
0 1 T750-p QEAWEEAtsEDssVV
0 1 S751-p EAWEEAtsEDssVVI
0 1 S754-p EEAtsEDssVVIVDV
0 1 S755-p EAtsEDssVVIVDVK
0 13 S771-p PSPRVDVsCEPLEGV
0 4 S782-p LEGVEKCsDsQsWED
1 7 S784-p GVEKCsDsQsWEDIA
0 4 S786-p EKCsDsQsWEDIAPE
0 4 T804-p CAENRLDtKEEKsVE
0 7 S809-p LDtKEEKsVEyEGDL
0 2 Y812-p KEEKsVEyEGDLKSG
0 1 T820-p EGDLKSGtAEtEPVE
0 2 T823-p LKSGtAEtEPVEQds
0 1 D829-ca EtEPVEQdssQPsLP
0 15 S830-p tEPVEQdssQPsLPL
1 14 S831-p EPVEQdssQPsLPLV
0 4 S834-p EQdssQPsLPLVRAD
0 43 T855-p QELQQPQtQEKtsNs
0 6 T859-p QPQtQEKtsNsLTED
0 7 S860-p PQtQEKtsNsLTEDs
0 16 S862-p tQEKtsNsLTEDsKM
0 1 S867-p sNsLTEDsKMANAKQ
0 4 S876-p MANAKQLssDAEAQK
0 5 S877-p ANAKQLssDAEAQKL
0 8 S892-p GKPSAHAsQsFCESS
0 3 S894-p PSAHAsQsFCESSsE
0 1 S900-p QsFCESSsETPFHFT
0 1 T919-p GDIIPPLtGAtPPLI
0 8 T922-p IPPLtGAtPPLIGHL
0 3 T938-p LEPKRHStPIGISNY
0 1 T952-p YPESTIAtSDVMSES
0 1 S970-p THDPILGsGKGDsGA
0 6 S975-p LGsGKGDsGAAPDVD
0 7 S993-p CLRMKLVsPEtEAsE
0 2 T996-p MKLVsPEtEAsEEsL
0 8 S999-p VsPEtEAsEEsLQFN
0 7 S1002-p EtEAsEEsLQFNLEK
0 1 T1012-p FNLEKPAtGERKNGS
0 1 S1019 tGERKNGSTAVAEsV
0 4 S1025-p GSTAVAEsVAsPQKt
1 20 S1028-p AVAEsVAsPQKtMsV
0 1 T1032-p sVAsPQKtMsVLsCI
0 1 S1034-p AsPQKtMsVLsCICE
0 1 S1037-p QKtMsVLsCICEARQ
0 2 S1050-p RQENEARsEDPPttP
0 2 T1055-p ARsEDPPttPIRGNL
0 23 T1056-p RsEDPPttPIRGNLL
0 17 S1067-p GNLLHFPssQGEEEK
0 30 S1068-p NLLHFPssQGEEEKE
1 10 S1086-p GDHTIRQsQQPMKPI
0 112 S1094-p QQPMKPIsPVKDPVs
0 1 - gap
0 118 S1101-p sPVKDPVsPAsQKMV
0 53 S1104-p KDPVsPAsQKMVIQG
0 5 - gap
0 1 - gap
0 5 S1113-p KMVIQGPssPQGEAM
1 32 S1114-p MVIQGPssPQGEAMV
0 1 T1122-p PQGEAMVtDVLEDQK
0 6 S1148-p KALIERPsQNNIGIQ
0 2 T1156-p QNNIGIQtMECsLrV
0 2 S1160-p GIQtMECsLrVPEtV
0 1 R1162-m1 QtMECsLrVPEtVSA
0 1 T1166-p CsLrVPEtVSAAtQT
0 2 T1171-p PEtVSAAtQTIkNVC
0 1 K1175-m1 SAAtQTIkNVCEQGT
0 1 S1202-p TVQTERGsGEKPVsA
0 4 S1208-p GsGEKPVsAPGDDtE
0 23 T1214-p VsAPGDDtEsLHsQG
0 24 S1216-p APGDDtEsLHsQGEE
3 29 S1219-p DDtEsLHsQGEEEFD
1 0 K1268 DGTEVERKVTEETEE
0 3 S1290-p CETEVSPsQtGGSSG
0 1 T1292-p TEVSPsQtGGSSGDL
0 10 T1315-p KASSLHRtssGtsLS
0 10 S1316-p ASSLHRtssGtsLSA
0 26 S1317-p SSLHRtssGtsLSAM
0 8 T1319-p LHRtssGtsLSAMHS
0 15 S1320-p HRtssGtsLSAMHSs
0 1 S1327-p sLSAMHSsGssGkGA
0 1 S1329-p SAMHSsGssGkGAGP
0 1 S1330-p AMHSsGssGkGAGPL
0 23 K1332-ac HSsGssGkGAGPLRG
0 1 K1332 HSsGssGKGAGPLRG
0 1 T1341-p AGPLRGKtsGTEPAD
0 3 S1342-p GPLRGKtsGTEPADF
0 2 S1354-p ADFALPSsRGGPGKL
0 1 R1355 DFALPSsRGGPGKLs
0 30 S1362-p RGGPGKLsPRKGVsQ
0 14 S1368-p LsPRKGVsQTGtPVC
0 3 T1372-p KGVsQTGtPVCEEDG
0 1 K1390-ac LGIRQGGkAPVtPrG
0 1 T1394-p QGGkAPVtPrGrGrr
2 0 R1396-me GkAPVtPrGrGrrGr
2 0 R1398-me APVtPrGrGrrGrPP
2 0 R1400-me VtPrGrGrrGrPPSR
2 0 R1401-me tPrGrGrrGrPPSRT
2 0 R1403-me rGrGrrGrPPSRTTG
0 16 S1426-p PLGIEDIsPNLsPDD
0 1 N1428 GIEDIsPNLsPDDKs
0 22 S1430-p EDIsPNLsPDDKsFs
0 2 S1435-p NLsPDDKsFsRVVPR
0 1 S1437-p sPDDKsFsRVVPRVP
0 1 T1450-p VPDSTRRtDVGAGAL
0 5 S1460-p GAGALRRsDsPEIPF
0 19 S1462-p GALRRsDsPEIPFQA
0 1 A1471 EIPFQAAAGPsDGLD
0 1 P1473 PFQAAAGPsDGLDAs
0 4 S1474-p FQAAAGPsDGLDAss
0 2 S1480-p PsDGLDAssPGNsFV
0 4 S1481-p sDGLDAssPGNsFVG
0 1 S1485-p DAssPGNsFVGLRVV
1 1 Y1500-p AKWSSNGyFYSGkIT
0 1 K1505-ac NGyFYSGkITRDVGA
1 4 Y1523-p KLLFDDGyECDVLGK
0 1 S1548 DTEVTALSEDEyFsA
0 15 Y1552-p TALSEDEyFsAGVVK
0 2 S1554-p LSEDEyFsAGVVKGH
0 13 Y1605-p EQYGLGPyEAVtPLt
2 17 T1609-p LGPyEAVtPLtKAAD
1 2 T1612-p yEAVtPLtKAADIsL
1 11 S1618-p LtKAADIsLDNLVEG
0 3 K1626-ac LDNLVEGkRKRRsNV
0 1 K1626-m1 LDNLVEGkRKRRsNV
0 1 K1626-ub LDNLVEGkRKRRsNV
0 5 S1631-p EGkRKRRsNVssPAt
0 5 S1634-p RKRRsNVssPAtPtA
0 6 S1635-p KRRsNVssPAtPtAs
0 14 T1638-p sNVssPAtPtAssss
0 5 T1640-p VssPAtPtAssssst
0 2 S1642-p sPAtPtAsssssttP
0 1 S1643-p PAtPtAsssssttPT
0 2 S1644-p AtPtAsssssttPTR
0 1 S1645-p tPtAsssssttPTRK
0 2 S1646-p PtAsssssttPTRKI
0 3 T1647-p tAsssssttPTRKIt
0 14 T1648-p AsssssttPTRKItE
0 2 T1654-p ttPTRKItEsPRAsM
0 5 S1656-p PTRKItEsPRAsMGV
0 1 S1660-p ItEsPRAsMGVLsGk
0 1 M1661 tEsPRAsMGVLsGkR
0 4 S1665-p RAsMGVLsGkRKLIt
0 16 K1667-ac sMGVLsGkRKLItsE
0 2 T1672-p sGkRKLItsEEERsP
0 8 S1673-p GkRKLItsEEERsPA
1 16 S1678-p ItsEEERsPAKRGRK
0 1 S1686-p PAKRGRKsATVKPGA
0 6 S1701-p VGAGEFVsPCEsGDN
0 3 S1705-p EFVsPCEsGDNtGEP
0 1 T1709-p PCEsGDNtGEPsALE
0 1 S1713-p GDNtGEPsALEEQRG
0 2 S1749-p SDKLASRsKLPDGPt
0 3 T1756-p sKLPDGPtGssEEEE
0 7 S1758-p LPDGPtGssEEEEEF
0 8 S1759-p PDGPtGssEEEEEFL
4 1 S1778-p FNKQYTEsQLRAGAG
0 1 S1929-p TDPSCPAsVLKCAEA
2674 : Phospho-53BP1 (Ser25/29) Antibody
2674 : Phospho-53BP1 (Ser25/29) Antibody
3428 : Phospho-53BP1 (Thr543) Antibody
6209 : Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb
2675 : Phospho-53BP1 (Ser1778) Antibody
  mouse

 
S6 __MDPTGSQLDSDFS
S25 PCLIIEDSQPESQVL
S29 IEDSQPESQVLEEDA
K54 LPNLQMHKENPVLDI
S63-p NPVLDIVsNPEQsAV
S68-p IVsNPEQsAVEQGDs
S75-p sAVEQGDsNssFNEH
S77-p VEQGDsNssFNEHLK
S78-p EQGDsNssFNEHLKE
T99 VESSHLGTSGSISQV
S102 SHLGTSGSISQVIER
S104 LGTSGSISQVIERLP
T116 RLPQPNRTSSALAVT
S118 PQPNRTSSALAVTVE
T123 TSSALAVTVEAASLP
- gap
K134 ASLPEEEKEEEELEE
S163 AAEDSASSQLGFGVL
S173 GFGVLELSQSQDVEE
S175 GVLELSQSQDVEEHT
Y185 VEEHTVPYDVNQEHL
S205 NSGSSPLSDVDASTA
K214 VDASTAIKCEEQPTE
P219 AIKCEEQPTEDIAMI
K241 PVTVQPGKGIHVVEE
S256-p QNLPLVRsEDRPssP
S261-p VRsEDRPssPQVSVA
S262-p RsEDRPssPQVSVAA
T272-p VSVAAVEtKEQVPAR
E284 PARELLEEGPQVQPS
S291 EGPQVQPSSEPEVSS
S298 SSEPEVSSTQEDLFD
T299 SEPEVSSTQEDLFDQ
T310 LFDQSSKTASDGCSt
S312 DQSSKTASDGCStPs
- gap
S316 KTASDGCStPsREEG
T317-p TASDGCStPsREEGG
S319-p SDGCStPsREEGGCS
T330 GGCSPVSTPATTLQL
T333 SPVSTPATTLQLLQL
P345 LQLSGQKPLVQESLS
S362-p SSDLVAPsPDAFRST
T369 sPDAFRSTPFIVPss
S375-p STPFIVPssPtEQGG
S376-p TPFIVPssPtEQGGR
T378-p FIVPssPtEQGGRKD
M390 RKDEPMDMSVIPAGG
S391 KDEPMDMSVIPAGGE
P394 PMDMSVIPAGGEPFQ
T421-p PLLPSQPtVsPQAST
S423-p LPSQPtVsPQASTPV
S446-p PGSLPIPsQPEFSHD
S458-p SHDIFIPsPsLEEPS
S460-p DIFIPsPsLEEPSDD
F494 SESEPKNFTDDLGLS
S501 FTDDLGLSMtGDsCK
T503-p DDLGLSMtGDsCKLM
S506-p GLSMtGDsCKLMLst
S512-p DsCKLMLstSEYSQS
T513-p sCKLMLstSEYSQSS
S514 CKLMLstSEYSQSSK
Y516 LMLstSEYSQSSKME
S517 MLstSEYSQSSKMEs
S519 stSEYSQSSKMEsLG
K521 SEYSQSSKMEsLGsP
K521 SEYSQSSKMEsLGsP
S524-p SQSSKMEsLGsPRtE
G526 SSKMEsLGsPRtEED
S527-p SKMEsLGsPRtEEDR
T530-p EsLGsPRtEEDRENt
T537-p tEEDRENtQIDDtEP
T542-p ENtQIDDtEPLsPVs
S546-p IDDtEPLsPVsNsKL
S549-p tEPLsPVsNsKLPAD
S551-p PLsPVsNsKLPADSE
N559 KLPADSENVLVTPSQ
S573 QDDQVEMSQNVDKAK
- gap
T584 DKAKEDETEDRGDCK
- gap
- gap
S611 DLTCDSGSQAVPsPA
S616-p SGSQAVPsPATRsEA
S621-p VPsPATRsEALssVL
S625-p ATRsEALssVLDQEE
S626-p TRsEALssVLDQEEA
- gap
S646-p HHPEEGFsGsEVEEV
S648-p PEEGFsGsEVEEVPE
S660-p VPETPCGsHREEPKE
S672 PKEEAMESIPLHLSL
S678 ESIPLHLSLTETQSE
T682 LHLSLTETQSEALCL
S684 LSLTETQSEALCLQK
S710-p EVETSVIsIDsPQKL
S713-p TSVIsIDsPQKLQVL
T736 PDTWEEATSEDSSVV
S737 DTWEEATSEDSSVVI
S740 EEATSEDSSVVIVDV
S741 EATSEDSSVVIVDVK
S757-p PSPRADVsCEPLEEV
S768-p LEEVEKCsDsQsWEG
S770-p EVEKCsDsQsWEGVA
S772-p EKCsDsQsWEGVAPE
T790-p CAENRLDtPEEKRIE
- gap
- gap
T806 DGDSKAETTEKDAVT
K809 SKAETTEKDAVTEDs
D815 EKDAVTEDsPQPPLP
S816-p KDAVTEDsPQPPLPS
- gap
- gap
- gap
- gap
S845 PQVQEKESPVTVDAE
- gap
- gap
- gap
- gap
S876-p EKAPACAsQsFCESS
S878-p APACAsQsFCESSSE
S884 QsFCESSSETPFHFT
T903 GDIIPPLTGAtPPLI
T906-p IPPLTGAtPPLIGHL
T922 LEPKRHSTPIGISNY
T936 YPESTIATSDVTSES
N954 INDPLLGNEKGDSES
S959 LGNEKGDSESAPEMD
S977-p SLKMKLVsPETEASE
T980 MKLVsPETEASEESL
S983 VsPETEASEESLQFS
S986 ETEASEESLQFSLEK
T996 FSLEKPTTAERKNGS
S1003 TAERKNGSTAIAEPV
- gap
S1012 AIAEPVASLQKPVPV
- gap
- gap
- gap
S1034-p QQEKEAQsEAPPSAP
S1039 AQsEAPPSAPDRANL
- gap
S1051 ANLLHFPSAQEEDKE
- gap
S1069 VTPKLRQSEQPVKPV
- gap
S1088-p DDAAPEDsAsPVsQQ
S1090-p AAPEDsAsPVsQQRA
S1093-p EDsAsPVsQQRAsQE
S1098-p PVsQQRAsQEPFsPA
- gap
- gap
S1103-p RAsQEPFsPAEDVME
T1111-p PAEDVMEtDLLEGLA
T1133 KMLMDRPTQSNIGIQ
T1141 QSNIGIQTVDHSLCA
S1145 GIQTVDHSLCAPETV
- gap
T1151 HSLCAPETVSAATQT
T1156 PETVSAATQTVKSVC
K1160 SAATQTVKSVCEQGT
S1187-p TVQTERGsGEKPAsA
S1193-p GsGEKPAsAPVDDtE
T1199-p AsAPVDDtEsLHsQG
S1201-p APVDDtEsLHsQGEE
S1204-p DDtEsLHsQGEEEFE
K1253-ub DGTEVERkVTEETEE
S1275 CETEVSPSQTGGSSG
T1277 TEVSPSQTGGSSGDL
T1300 KASSSHHTSSGTSLS
S1301 ASSSHHTSSGTSLSA
S1302 SSSHHTSSGTSLSAI
T1304 SHHTSSGTSLSAIHS
S1305 HHTSSGTSLSAIHSS
S1312 SLSAIHSSGSSGrGA
S1314 SAIHSSGSSGrGAGP
S1315 AIHSSGSSGrGAGPL
R1317 HSSGSSGRGAGPLKG
R1317-m1 HSSGSSGrGAGPLKG
A1326 AGPLKGKASGTEAAD
S1327 GPLKGKASGTEAADF
S1339 ADFALPSSrGGPGKL
R1340-m1 DFALPSSrGGPGKLs
S1347-p rGGPGKLsPRKGISQ
S1353 LsPRKGISQTGAPVC
- gap
K1375 LGIRQGGKAPVTPRG
T1379 QGGKAPVTPRGRGRR
R1381 GKAPVTPRGRGRRGR
R1383 APVTPRGRGRRGRPP
R1385 VTPRGRGRRGRPPSR
R1386 TPRGRGRRGRPPSRT
R1388 RGRGRRGRPPSRTTG
S1411-p PLGVEDIsPsMsPDD
S1413-p GVEDIsPsMsPDDKs
S1415-p EDIsPsMsPDDKsFt
S1420-p sMsPDDKsFtRIMPR
T1422-p sPDDKsFtRIMPRVP
T1435 VPDSTKRTDASSSTL
S1445-p SSSTLRRsDsPEIPF
S1447-p STLRRsDsPEIPFQA
T1456-p EIPFQAAtGssDGLD
S1458-p PFQAAtGssDGLDSS
S1459-p FQAAtGssDGLDSSS
S1465 ssDGLDSSSSGNSFV
S1466 sDGLDSSSSGNSFVG
S1470 DSSSSGNSFVGLRVV
Y1485 AKWSSNGYFYSGKIT
K1490 NGYFYSGKITRDVGA
Y1508 KLLFDDGYECDVLGK
S1533-p DTEVTALsEDEYFSA
Y1537 TALsEDEYFSAGVVK
S1539 LsEDEYFSAGVVKGH
Y1590 EQYGLGPYEAVTPLT
T1594 LGPYEAVTPLTKAAD
T1597 YEAVTPLTKAADIsL
S1603-p LTKAADIsLDNLVEG
K1611 LDNLVEGKRKRRsNI
K1611 LDNLVEGKRKRRsNI
K1611 LDNLVEGKRKRRsNI
S1616-p EGKRKRRsNIssPVT
S1619-p RKRRsNIssPVTPTA
S1620-p KRRsNIssPVTPTAA
T1623 sNIssPVTPTAASsS
T1625 IssPVTPTAASsSST
- gap
S1628 PVTPTAASsSSTtPT
S1629-p VTPTAASsSSTtPTR
S1630 TPTAASsSSTtPTRK
S1631 PTAASsSSTtPTRKA
T1632 TAASsSSTtPTRKAT
T1633-p AASsSSTtPTRKATE
T1639 TtPTRKATEsPRASt
S1641-p PTRKATEsPRAStGV
S1645 ATEsPRAStGVPSGK
T1646-p TEsPRAStGVPSGKR
S1650 RAStGVPSGKRKLPT
K1652 StGVPSGKRKLPTSE
T1657 SGKRKLPTSEEERsP
S1658 GKRKLPTSEEERsPA
S1663-p PTSEEERsPAKRGRK
S1671 PAKRGRKSATVKPGT
S1686 VGAAEFVSPCETGDN
T1690 EFVSPCETGDNIGEP
- gap
S1698 GDNIGEPSVLEEPRG
S1734 SDKLASRSKLLDGPT
T1741 SKLLDGPTGssEEEE
S1743-p LLDGPTGssEEEEEF
S1744-p LDGPTGssEEEEEFL
- gap
S1914 TDPSCPASVLKCAEA
6209 : Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb
  rat

 
S11 EQMDPTGSQLDSDFS
S30 PCLIIEDSQPESQAL
S34 IEDSQPESQALEEDA
K59 LPNLQMHKENPVLDI
S68 NPVLDIMSNPEQTVA
T73 IMSNPEQTVAEQGDS
S80 TVAEQGDSNSSFSEH
S82 AEQGDSNSSFSEHLK
S83 EQGDSNSSFSEHLKE
T104 VESSHLGTSGPISQV
P107 SHLGTSGPISQVIER
S109 LGTSGPISQVIERLP
T121 RLPQPNRTSSALGVT
S123 PQPNRTSSALGVTVE
T128 TSSALGVTVEAASLA
- gap
K139 ASLAEEEKEEELEEE
S169 LAEDSASSQLGFGVL
S179-p GFGVLELsQSQDVEE
S181 GVLELsQSQDVEEHT
Y191 VEEHTVPYDVKQEHL
S211 NSGSTQLSDVDANTD
K223 NTDGKAIKCEEQSTD
S228 AIKCEEQSTDAISII
K249 PVTVQPSKGSHVVEE
S264 QNLPLVRSEDLPSsP
S269 VRSEDLPSsPQVSVA
S270-p RSEDLPSsPQVSVAA
T280 VSVAAVETKEQVPAQ
G292 PAQELLEGGLQVQVS
S299 GGLQVQVSSEPEVSS
S306 SSEPEVSSTQEDLFD
T307 SEPEVSSTQEDLFDQ
T318 LFDQSSKTASDGCST
S320 DQSSKTASDGCSTPS
- gap
S324 KTASDGCSTPSREEG
T325 TASDGCSTPSREEGG
S327 SDGCSTPSREEGGCS
T338 GGCSPVSTPATTLQL
T341 SPVSTPATTLQLLQL
P353 LQLSGQKPLVQESLS
S370 SSDLVAPSPDAFRST
T377 SPDAFRSTPFIVPSs
S383 STPFIVPSsPTEQGQ
S384-p TPFIVPSsPTEQGQR
T386 FIVPSsPTEQGQRKD
M398 RKDEPMDMSVIPEGG
S399 KDEPMDMSVIPEGGE
P402 PMDMSVIPEGGEHFQ
A429 PLLPSQPAVsPQAST
S431-p LPSQPAVsPQASTPV
S454 PASLPIPSQPEFSHD
S466-p SHDIFIPsPSLEEPS
S468 DIFIPsPSLEEPSND
F502 SESEPKNFTDDLGLS
S509 FTDDLGLSMTGDSCK
T511 DDLGLSMTGDSCKLM
S514 GLSMTGDSCKLMLST
S520 DSCKLMLSTSECSQS
T521 SCKLMLSTSECSQSS
S522 CKLMLSTSECSQSSK
C524 LMLSTSECSQSSKME
S525 MLSTSECSQSSKMEs
S527 STSECSQSSKMEsLG
K529 SECSQSSKMEsLGsP
K529 SECSQSSKMEsLGsP
S532-p SQSSKMEsLGsPRTE
G534 SSKMEsLGsPRTEEV
S535-p SKMEsLGsPRTEEVG
T538 EsLGsPRTEEVGENT
T545 TEEVGENTQVEDTEP
T550 ENTQVEDTEPSsPVt
S554-p VEDTEPSsPVtKSKL
T557-p TEPSsPVtKSKLPAE
S559 PSsPVtKSKLPAESE
S567 KLPAESESVLVNPTQ
S581 QDDQVEMSQNVDKAK
- gap
- gap
- gap
- gap
S626 DLTCDSGSQAVPSPA
S631 SGSQAVPSPATRSEA
S636 VPSPATRSEALssVL
S640-p ATRSEALssVLDQEE
S641-p TRSEALssVLDQEEA
- gap
S661 HHPEEEFSGSEVEEV
S663 PEEEFSGSEVEEVPE
S675 VPETPCGSHREESKE
S687 SKEEPMESIPLHLSL
S693 ESIPLHLSLTETQSE
T697 LHLSLTETQSEALCL
S699 LSLTETQSEALCLQK
S725 EVETSVISIDSPQKL
S728 TSVISIDSPQKLPVL
T751 PETWEEATSEDSSVV
S752 ETWEEATSEDSSVVI
S755 EEATSEDSSVVIVDV
S756 EATSEDSSVVIVDVK
S772 PSPRVDISCEPVEGV
S783 VEGVGKCSDSQSLEG
S785 GVGKCSDSQSLEGAA
S787 GKCSDSQSLEGAAPE
T805-p CAENRLNtPEEKRVE
- gap
- gap
T821 DGDSKAETTEKNSVT
K824 SKAETTEKNSVTEDs
D830 EKNSVTEDsPQPPLP
S831-p KNSVTEDsPQPPLPS
- gap
- gap
- gap
- gap
S860-p PQVQEKEsPVTLDAK
- gap
- gap
- gap
S876 ADDKHLGSEGSCQQL
S891 EKAPARASQSFCESS
S893 APARASQSFCESSSE
S899 QSFCESSSETPFHFT
T918 GDIIPPLTGATPPLI
T921 IPPLTGATPPLIGHL
T937 LEPKRHSTPIGISNY
T951 YPESTIATSDVMSES
N969 INDPLLGNEKGDSES
S974 LGNEKGDSESAPEMD
S992-p SLKMKLVsPETEASE
T995 MKLVsPETEASEESL
S998 VsPETEASEESLQFS
S1001 ETEASEESLQFSLEK
T1011 FSLEKPTTAERRNGs
S1018-p TAERRNGsTAIAEPV
- gap
S1027 AIAEPVASPQKPMSV
- gap
S1033 ASPQKPMSVFGCIYE
- gap
S1049 QQEEEAQSGDPPStP
S1054 AQSGDPPStPVRTNL
T1055-p QSGDPPStPVRTNLL
S1066 TNLLHFPSAQEEDRE
- gap
S1084 ATPQLRQSEQPVKLI
- gap
S1103 DAAASEDSASSVSQQ
S1105 AASEDSASSVSQQRA
S1108 EDSASSVSQQRAsQG
S1113-p SVSQQRAsQGsLsPQ
S1116-p QQRAsQGsLsPQEEV
- gap
S1118-p RAsQGsLsPQEEVME
- gap
T1148 KILMERPTQSNIGIQ
T1156 QSNIGIQTMDHSLCA
S1160 GIQTMDHSLCAPETV
- gap
T1166 HSLCAPETVSAATQT
T1171 PETVSAATQTVKNVC
K1175 SAATQTVKNVCEQGT
S1202 TVQTERGSGEKPASA
S1208 GSGEKPASAPVDDTE
T1214 ASAPVDDTESLHSQG
S1216 APVDDTESLHSQGEE
S1219 DDTESLHSQGEEEFE
K1268 DGTEVERKVTEETEE
S1290 CETEVSPSQTGGSSG
T1292 TEVSPSQTGGSSGDL
T1315 KASSSHHTSSGTSLS
S1316 ASSSHHTSSGTSLSA
S1317 SSSHHTSSGTSLSAI
T1319 SHHTSSGTSLSAIHS
S1320 HHTSSGTSLSAIHSS
S1327 SLSAIHSSGSSGRGA
S1329 SAIHSSGSSGRGAGP
S1330 AIHSSGSSGRGAGPL
R1332 HSSGSSGRGAGPLKG
R1332 HSSGSSGRGAGPLKG
T1341 AGPLKGKTSGTEPAD
S1342 GPLKGKTSGTEPADF
S1354 ADFALPSSRGGPGKL
R1355 DFALPSSRGGPGKLs
S1362-p RGGPGKLsPRKGISQ
S1368 LsPRKGISQTGAPVC
- gap
K1390 LGIRQGGKAPVTPRG
T1394 QGGKAPVTPRGRGRR
R1396 GKAPVTPRGRGRRGR
R1398 APVTPRGRGRRGRPP
R1400 VTPRGRGRRGRPPSR
R1401 TPRGRGRRGRPPSRT
R1403 RGRGRRGRPPSRTTG
S1426 PLGIEDTSPSMSPDD
S1428 GIEDTSPSMSPDDKS
S1430 EDTSPSMSPDDKSFT
S1435 SMSPDDKSFTRIMPR
T1437 SPDDKSFTRIMPRVP
M1450 VPDSTKRMDASSGAL
S1460 SSGALRRSDSPEIPF
S1462 GALRRSDSPEIPFQA
T1471 EIPFQAATGSSDGLD
S1473 PFQAATGSSDGLDSS
S1474 FQAATGSSDGLDSSS
S1480 SSDGLDSSSSGNSFV
S1481 SDGLDSSSSGNSFVG
S1485 DSSSSGNSFVGLRVV
Y1500 AKWSSNGYFYSGKIT
K1505 NGYFYSGKITRDVGA
Y1523 KLLFDDGYECDVLGK
S1548 DTEVTALSEDEYFSA
Y1552 TALSEDEYFSAGVVK
S1554 LSEDEYFSAGVVKGH
Y1605 EQYGLGPYEAVTPLT
T1609 LGPYEAVTPLTKAAD
T1612 YEAVTPLTKAADISL
S1618 LTKAADISLDNLVEG
K1626 LDNLVEGKRKRRSNI
K1626 LDNLVEGKRKRRSNI
K1626 LDNLVEGKRKRRSNI
S1631 EGKRKRRSNISSPAT
S1634 RKRRSNISSPATPtA
S1635 KRRSNISSPATPtAs
T1638 SNISSPATPtAsSSS
T1640-p ISSPATPtAsSSSSt
S1642-p SPATPtAsSSSStTP
S1643 PATPtAsSSSStTPT
S1644 ATPtAsSSSStTPTR
S1645 TPtAsSSSStTPTRK
S1646 PtAsSSSStTPTRKT
T1647-p tAsSSSStTPTRKTT
T1648 AsSSSStTPTRKTTE
T1654 tTPTRKTTESPRASM
S1656 PTRKTTESPRASMGV
S1660 TTESPRASMGVPSGK
- gap
S1665 RASMGVPSGKRKLTT
K1667 SMGVPSGKRKLTTSE
T1672 SGKRKLTTSEEERsP
S1673 GKRKLTTSEEERsPA
S1678-p TTSEEERsPAKRGRK
S1686 PAKRGRKSATVKPGT
S1701-p VGAAELVsPCESGDN
S1705 ELVsPCESGDNTGEP
T1709 PCESGDNTGEPSVLE
S1713 GDNTGEPSVLEEPRG
S1749 SDKLASRSKLLDGPT
T1756 SKLLDGPTGSSEEEE
S1758 LLDGPTGSSEEEEEF
S1759 LDGPTGSSEEEEEFL
- gap
S1929 TDPSCPASVLKCAEA
6209 : Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.