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GNGT1 (human)

Overview GNGT1 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family. Note: This description may include information from UniProtKB. Protein type: G protein, heterotrimeric; G protein; G protein, heterotrimeric gamma Cellular Component: plasma membrane; heterotrimeric G-protein complex Molecular Function: GTPase activity; signal transducer activity Biological Process: G-protein coupled receptor protein signaling pathway; synaptic transmission; protein localization; eye photoreceptor cell development; GTP catabolic process; phototransduction; signal transduction Reference #:  P63211 (UniProtKB) Alt. Names/Synonyms: GBG1; GNG1; GNGT1; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; Guanine nucleotide-binding protein G(T) subunit gamma-T1; Transducin gamma chain Gene Symbols: GNGT1 Molecular weight: 8,496 Da Basal Isoelectric point: 4.76  Predict pI for various phosphorylation states CST Pathways:  GPCRs Signaling to MAPK/Erk  |  Parkinson's Disease  |  Phospholipase Signaling  |  PI3K/Akt Signaling

Select Structure to View Below GNGT1

STRING  |  Scansite  |  Phospho.ELM  |  Pfam  |  DISEASE  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		Y43-p	CCEEVRDyVEERsGE
0	1		S48-p	RDyVEERsGEDPLVK

	mouse
Y43	CCEEVRDYIEERSGE
S48	RDYIEERSGEDPLVK

	cow
Y43	CCEEFRDYVEERSGE
S48	RDYVEERSGEDPLVK

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