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Protein Page:
NCL (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
NCL the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and preribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-RNA transcription and ribosome assembly. Note: This description may include information from UniProtKB.
Protein type: Helicase; DNA binding protein; RNA binding protein; Nuclear receptor co-regulator
Cellular Component: nucleoplasm; nucleolus; cell cortex; ribonucleoprotein complex; nucleus
Molecular Function: protein C-terminus binding; identical protein binding; protein binding; RNA binding; nucleotide binding; telomeric DNA binding
Biological Process: angiogenesis
Reference #:  P19338 (UniProtKB)
Alt. Names/Synonyms: C23; FLJ45706; FLJ59041; NCL; NUCL; Nucleolin; Protein C23
Gene Symbols: NCL
Molecular weight: 76,614 Da
Basal Isoelectric point: 4.6  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

NCL

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 53 K9-a VKLAKAGkNQGDPkk
1 51 K15-a GkNQGDPkkMAPPPK
0 4 K16-a kNQGDPkkMAPPPKE
0 32 S28-p PKEVEEDsEDEEMsE
1 28 S34-p DsEDEEMsEDEEDDs
0 14 D40 MsEDEEDDssGEEVV
0 29 S41-p sEDEEDDssGEEVVI
0 15 S42-p EDEEDDssGEEVVIP
0 1 T59 KGKKAAATSAkkVVV
0 7 K62-a KAAATSAkkVVVsPt
1 0 K63-a AAATSAkkVVVsPtk
1 56 S67-p SAkkVVVsPtkkVAV
0 32 T69-p kkVVVsPtkkVAVAt
1 56 K70-a kVVVsPtkkVAVAtP
0 9 K71-a VVVsPtkkVAVAtPA
1 28 T76-p tkkVAVAtPAkkAAV
1 26 K79-a VAVAtPAkkAAVtPG
1 0 K80-a AVAtPAkkAAVtPGk
0 7 T84-p PAkkAAVtPGkkAAA
1 76 K87-a kAAVtPGkkAAAtPA
1 3 K88-a AAVtPGkkAAAtPAk
0 11 T92-p PGkkAAAtPAkKTVt
0 4 K95-a kAAAtPAkKTVtPAk
0 19 T99-p tPAkKTVtPAkAVtt
2 30 K102-a kKTVtPAkAVttPGk
0 2 T105-p VtPAkAVttPGkkGA
0 7 T106-p tPAkAVttPGkkGAt
1 35 K109-a kAVttPGkkGAtPGk
1 8 K110-a AVttPGkkGAtPGkA
0 6 T113-p tPGkkGAtPGkALVA
2 32 K116-a kkGAtPGkALVAtPG
2 34 T121-p PGkALVAtPGkkGAA
1 186 K124-a ALVAtPGkkGAAIPA
1 1 K125-a LVAtPGkkGAAIPAk
0 3 K132-a kGAAIPAkGAkNGKN
1 1 K135-a AIPAkGAkNGKNAKK
0 110 S145-p KNAKKEDsDEEEDDD
0 66 S153-p DEEEDDDsEEDEEDD
0 42 E157 DDDsEEDEEDDEDED
1 37 S184-p AAAAAPAsEDEDDED
1 45 S206-p DDDEEDDsEEEAMEt
0 2 T213-p sEEEAMEttPAKGKK
0 5 T214-p EEEAMEttPAKGKKA
0 5 T301-p KKQKVEGtEPttAFN
0 2 T304-p KVEGtEPttAFNLFV
0 3 T305-p VEGtEPttAFNLFVG
0 1 K318-a VGNLNFNkSAPELkT
0 4 K318-u VGNLNFNkSAPELkT
0 11 K324-u NkSAPELkTGISDVF
0 1 K333-a GISDVFAkNDLAVVD
0 27 K333-u GISDVFAkNDLAVVD
0 1 I343 LAVVDVRIGMTRkFG
0 1 M345 VVDVRIGMTRkFGYV
0 2 K348-u VRIGMTRkFGYVDFE
0 4 S356-p FGYVDFEsAEDLEKA
0 4 T367-p LEKALELtGLkVFGN
0 8 K370-a ALELtGLkVFGNEIk
0 37 K370-u ALELtGLkVFGNEIk
0 1 K377-a kVFGNEIkLEKPKGK
0 2 K387-a KPKGKDSkKERDART
0 8 K398-a DARTLLAkNLPykVt
0 3 K398-u DARTLLAkNLPykVt
0 14 P401 TLLAkNLPykVtQDE
0 7 Y402-p LLAkNLPykVtQDEL
0 6 K403-a LAkNLPykVtQDELk
0 20 K403-u LAkNLPykVtQDELk
0 16 T405-p kNLPykVtQDELkEV
0 2 K410-u kVtQDELkEVFEDAA
0 1 S423-p AAEIRLVsKDGKsKG
0 1 S428-p LVsKDGKsKGIAYIE
0 1 K444-a KTEADAEkTFEEkQG
1 3 K449-a AEkTFEEkQGTEIDG
0 1 K449 AEkTFEEKQGTEIDG
0 7 S458-p GTEIDGRsIsLyytG
0 3 S460-p EIDGRsIsLyytGEk
1 64 Y462-p DGRsIsLyytGEkGQ
0 4 Y463-p GRsIsLyytGEkGQN
0 2 T464-p RsIsLyytGEkGQNQ
0 3 K467-a sLyytGEkGQNQDyR
0 45 K467-u sLyytGEkGQNQDyR
0 20 Y473-p EkGQNQDyRGGkNST
0 8 K477-u NQDyRGGkNSTWSGE
0 1 T487-p TWSGESKtLVLSNLs
0 1 S494-p tLVLSNLsYSAtEET
0 1 T498-p SNLsYSAtEETLQEV
0 4 E499 NLsYSAtEETLQEVF
0 4 K508-u TLQEVFEkATFIkVP
0 1 K513-a FEkATFIkVPQNQNG
0 60 K513-u FEkATFIkVPQNQNG
0 7 K521-u VPQNQNGkSkGyAFI
0 20 K523-u QNQNGkSkGyAFIEF
0 3 Y525-p QNGkSkGyAFIEFAs
0 8 S532-p yAFIEFAsFEDAkEA
0 6 K537-u FAsFEDAkEALNSCN
0 17 K545-a EALNSCNkREIEGRA
0 11 K545-u EALNSCNkREIEGRA
0 1 R561-m1 RLELQGPrGsPNARS
0 21 S563-p ELQGPrGsPNARSQP
0 1 K572-a NARSQPSkTLFVkGL
0 11 K572-u NARSQPSkTLFVkGL
0 2 K577-a PSkTLFVkGLsEDTT
0 15 K577-u PSkTLFVkGLsEDTT
0 11 S580-p TLFVkGLsEDTTEET
0 8 K589-u DTTEETLkESFDGSV
0 17 T602-p SVRARIVtDrETGSS
0 1 R604-m1 RARIVtDrETGSSkG
0 8 K610-u DrETGSSkGFGFVDF
0 18 S619-p FGFVDFNsEEDAKAA
0 1 K627 EEDAKAAKEAMEDGE
1 1 T641-p EIDGNKVtLDWAkPK
0 5 K646-a KVtLDWAkPKGEGGF
2 1 R656-m2 GEGGFGGrGGGrGGF
0 13 R656-m1 GEGGFGGrGGGrGGF
2 1 R660-m2 FGGrGGGrGGFGGrG
0 10 R660-m1 FGGrGGGrGGFGGrG
2 0 R666-m2 GrGGFGGrGGGrGGr
2 0 R670-m2 FGGrGGGrGGrGGFG
2 1 R673-m2 rGGGrGGrGGFGGrG
1 1 R679-m2 GrGGFGGrGrGGFGG
1 1 R681-m2 GGFGGrGrGGFGGrG
0 4 R681-m1 GGFGGrGrGGFGGrG
1 1 R687-m2 GrGGFGGrGGFRGGR
0 8 R687-m1 GrGGFGGrGGFRGGR
1 0 R691 FGGrGGFRGGRGGGG
1 0 R694 rGGFRGGRGGGGDHK
0 5 R694 rGGFRGGRGGGGDHK
0 3 K705 GDHKPQGKKtKFE__
1 0 T707-p HKPQGKKtKFE____
  mouse

 
K9-a VKLAKAGkTHGEAkk
K15-a GkTHGEAkkMAPPPK
K16-a kTHGEAkkMAPPPKE
S28-p PKEVEEDsEDEEMsE
S34-p DsEDEEMsEDEDDss
S40-p MsEDEDDssGEEEVV
S41-p sEDEDDssGEEEVVI
G42 EDEDDssGEEEVVIP
T59-p KGKKATTtPAKKVVV
K62 KATTtPAKKVVVSQT
K63 ATTtPAKKVVVSQTk
S67 PAKKVVVSQTkkAAV
T69 KKVVVSQTkkAAVPt
K70-a KVVVSQTkkAAVPtP
K71-a VVVSQTkkAAVPtPA
T76-p TkkAAVPtPAkKAAV
K79-a AAVPtPAkKAAVtPG
K80 AVPtPAkKAAVtPGk
T84-p PAkKAAVtPGkKAVA
K87-a KAAVtPGkKAVAtPA
K88 AAVtPGkKAVAtPAk
T92-p PGkKAVAtPAkKNIt
K95-a KAVAtPAkKNItPAk
T99-p tPAkKNItPAkVIPt
K102-a kKNItPAkVIPtPGK
P105 ItPAkVIPtPGKKGA
T106-p tPAkVIPtPGKKGAA
K109 kVIPtPGKKGAAQAk
K110 VIPtPGKKGAAQAkA
A113 tPGKKGAAQAkALVP
K116-a KKGAAQAkALVPtPG
T121-p QAkALVPtPGkKGAA
K124-a ALVPtPGkKGAATPA
K125 LVPtPGkKGAATPAK
K132 KGAATPAKGAKNGKN
K135 ATPAKGAKNGKNAKK
S145-p KNAKKEDsDEDEDEE
D153 DEDEDEEDEDDsDED
S157-p DEEDEDDsDEDEDDE
S189-p AAPAAPAsEDEEDDE
S212-p DEEEEDDsEEEVMEI
I219 sEEEVMEITTAKGKK
T220 EEEVMEITTAKGKKT
S303-p KKQKVEGsEPttPFN
T306-p KVEGsEPttPFNLFI
T307-p VEGsEPttPFNLFIG
K320 IGNLNPNKSVNELkF
K320-u IGNLNPNkSVNELkF
K326-u NkSVNELkFAISELF
K335 AISELFAKNDLAVVD
K335-u AISELFAkNDLAVVD
T345-p LAVVDVRtGtNRKFG
T347-p VVDVRtGtNRKFGYV
K350 VRtGtNRKFGYVDFE
S358-p FGYVDFEsAEDLEKA
T369 LEKALELTGLkVFGN
K372 ALELTGLKVFGNEIK
K372-u ALELTGLkVFGNEIK
K379 kVFGNEIKLEKPKGR
K389-a KPKGRDSkKVRAART
K400 AARTLLAKNLsFNIT
K400-u AARTLLAkNLsFNIT
S403-p TLLAkNLsFNITEDE
F404 LLAkNLsFNITEDEL
N405 LAkNLsFNITEDELK
N405 LAkNLsFNITEDELK
T407 kNLsFNITEDELKEV
K412 NITEDELKEVFEDAM
S425 AMEIRLVSQDGKSKG
S430 LVSQDGKSKGIAYIE
K446 KSEADAEKNLEEkQG
K451 AEKNLEEKQGAEIDG
K451-u AEKNLEEkQGAEIDG
S460-p GAEIDGRsVSLyYTG
S462 EIDGRsVSLyYTGEk
Y464-p DGRsVSLyYTGEkGQ
Y465 GRsVSLyYTGEkGQR
T466 RsVSLyYTGEkGQRQ
K469 SLyYTGEKGQRQERT
K469-u SLyYTGEkGQRQERT
- gap
K478 QRQERTGKTSTWSGE
T488 TWSGESKTLVLSNLs
S495-p TLVLSNLsYSAtkET
T499-p SNLsYSAtkETLEEV
K500-u NLsYSAtkETLEEVF
K509-u TLEEVFEkATFIKVP
K514 FEkATFIKVPQNPHG
K514 FEkATFIKVPQNPHG
K522 VPQNPHGKPKGYAFI
K524 QNPHGKPKGYAFIEF
Y526 PHGKPKGYAFIEFAS
S533 YAFIEFASFEDAKEA
K538 FASFEDAKEALNSCN
K546 EALNSCNKMEIEGRT
K546-u EALNSCNkMEIEGRT
- under review  
- gap
K569 NSRSQPSKTLFVkGL
K569 NSRSQPSKTLFVkGL
K574 PSKTLFVKGLsEDTT
K574-u PSKTLFVkGLsEDTT
S577-p TLFVkGLsEDTTEET
K586-u DTTEETLkESFEGSV
T599 SVRARIVTDRETGSS
R601 RARIVTDRETGSSkG
K607-u DRETGSSkGFGFVDF
S616-p FGFVDFNsEEDAKAA
K624-u EEDAKAAkEAMEDGE
T638 EIDGNKVTLDWAKPK
K643 KVTLDWAKPKGEGGF
R653 GEGGFGGRGGGrGGF
R653-m1 GEGGFGGrGGGrGGF
R657 FGGrGGGRGGFGGRG
R657-m1 FGGrGGGrGGFGGRG
R663 GrGGFGGRGGGRGGR
R667 FGGRGGGRGGRGGFG
R670 RGGGRGGRGGFGGRG
R676 GRGGFGGRGRGGFGG
R678 GGFGGRGRGGFGGrG
R678 GGFGGRGRGGFGGrG
R684 GRGGFGGRGGFRGGr
R684-m1 GRGGFGGrGGFRGGr
R688 FGGrGGFRGGrGGGG
R691 rGGFRGGRGGGGDFK
R691-m1 rGGFRGGrGGGGDFK
K702-a GDFKPQGkKTKFE__
T704 FKPQGkKTKFE____
  rat

► Hide Isoforms
 
K9 VKLAKAGKTHGESKK
K15 GKTHGESKKMAPPPK
K16 KTHGESKKMAPPPKE
S28-p PKEVEEDsEDEEMsE
S34-p DsEDEEMsEDEDDss
S40-p MsEDEDDssGEEEVV
S41-p sEDEDDssGEEEVVI
G42 EDEDDssGEEEVVIP
T59 KGKKATTTPAKKVVV
K62 KATTTPAKKVVVSQT
K63 ATTTPAKKVVVSQTK
S67 PAKKVVVSQTKKAAV
T69 KKVVVSQTKKAAVPT
K70 KVVVSQTKKAAVPTP
K71 VVVSQTKKAAVPTPA
T76 TKKAAVPTPAKKAAV
K79 AAVPTPAKKAAVTPG
K80 AVPTPAKKAAVTPGK
T84 PAKKAAVTPGKKAAA
K87 KAAVTPGKKAAATPA
K88 AAVTPGKKAAATPAK
T92 PGKKAAATPAKKAVT
K95 KAAATPAKKAVTPAK
T99 TPAKKAVTPAKVVPT
K102 KKAVTPAKVVPTPGK
P105 VTPAKVVPTPGKKGA
T106 TPAKVVPTPGKKGAA
K109 KVVPTPGKKGAAQAK
K110 VVPTPGKKGAAQAKA
A113 TPGKKGAAQAKALVP
K116 KKGAAQAKALVPTPG
T121 QAKALVPTPGKKGAV
K124 ALVPTPGKKGAVTPA
K125 LVPTPGKKGAVTPAK
K132 KGAVTPAKGAKNGKN
K135 VTPAKGAKNGKNAKK
S145-p KNAKKEDsDEDEDEE
D153 DEDEDEEDEDDsDED
S157-p DEEDEDDsDEDEDEE
S187-p AAPAAPAsEDEDEED
S213-p EEEEEDDsEEEVMEI
I220 sEEEVMEITPAKGKK
T221 EEEVMEITPAKGKKT
S305 KKQKIEGSEPTTPFN
T308 KIEGSEPTTPFNLFI
T309 IEGSEPTTPFNLFIG
K322 IGNLNPNKSVAELKV
K322 IGNLNPNKSVAELKV
K328 NKSVAELKVAISELF
K337 AISELFAKNDLAAVD
K337 AISELFAKNDLAAVD
T347 LAAVDVRTGTNRKFG
T349 AVDVRTGTNRKFGYV
K352 VRTGTNRKFGYVDFE
S360 FGYVDFESAEDLEKA
T371 LEKALELTGLKVFGN
K374 ALELTGLKVFGNEIK
K374 ALELTGLKVFGNEIK
K381 KVFGNEIKLEKPKGR
K391 KPKGRDSKKVRAART
K402 AARTLLAKNLSFNIT
K402 AARTLLAKNLSFNIT
S405 TLLAKNLSFNITEDE
F406 LLAKNLSFNITEDEL
N407 LAKNLSFNITEDELK
N407 LAKNLSFNITEDELK
T409 KNLSFNITEDELKEV
K414 NITEDELKEVFEDAV
S427 AVEIRLVSQDGRSKG
S432 LVSQDGRSKGIAYIE
K448 KSEADAEKNLEEKQG
K453 AEKNLEEKQGAEIDG
K453 AEKNLEEKQGAEIDG
S462 GAEIDGRSVSLyYTG
S464 EIDGRSVSLyYTGEK
Y466-p DGRSVSLyYTGEKGQ
Y467 GRSVSLyYTGEKGQR
T468 RSVSLyYTGEKGQRQ
K471 SLyYTGEKGQRQERT
K471 SLyYTGEKGQRQERT
- gap
K480 QRQERTGKNSTWSGE
T490 TWSGESKTLVLSNLS
S497 TLVLSNLSYSATEET
T501 SNLSYSATEETLQEV
E502 NLSYSATEETLQEVF
K511 TLQEVFEKATFIKVP
K516 FEKATFIKVPQNPHG
K516 FEKATFIKVPQNPHG
K524 VPQNPHGKSKGYAFI
K526 QNPHGKSKGYAFIEF
Y528 PHGKSKGYAFIEFAS
S535 YAFIEFASFEDAKEA
K540 FASFEDAKEALNSCN
K548 EALNSCNKMEIEGRT
K548 EALNSCNKMEIEGRT
R564 RLELQGPRGsPNARS
S566-p ELQGPRGsPNARSQP
K575 NARSQPSKTLFVKGL
K575 NARSQPSKTLFVKGL
K580 PSKTLFVKGLSEDTT
K580 PSKTLFVKGLSEDTT
S583 TLFVKGLSEDTTEET
K592 DTTEETLKESFEGSV
T605 SVRARIVTDRETGSS
R607 RARIVTDRETGSSKG
K613 DRETGSSKGFGFVDF
S622 FGFVDFNSEEDAKAA
K630 EEDAKAAKEAMEDGE
T644 EIDGNKVTLDWAKPK
K649 KVTLDWAKPKGEGGF
R659-m2 GEGGFGGrGGGrGGF
R659-m1 GEGGFGGrGGGrGGF
R663-m2 FGGrGGGrGGFGGrG
R663-m1 FGGrGGGrGGFGGrG
R669-m2 GrGGFGGrGGGrGGr
R673-m2 FGGrGGGrGGrGGFG
R676-m2 rGGGrGGrGGFGGrG
R682-m2 GrGGFGGrGrGGFGG
R684-m2 GGFGGrGrGGFGGrG
R684 GGFGGrGRGGFGGrG
R690-m2 GrGGFGGrGGFrGGr
R690 GrGGFGGRGGFrGGr
R694-m2 FGGrGGFrGGrGGGG
R697-m2 rGGFrGGrGGGGDFK
R697 rGGFrGGRGGGGDFK
K708 GDFKPQGKKTKFE__
T710 FKPQGKKTKFE____
  NCL iso6  
K9 VKLAKAGKTHGESKK
K15 GKTHGESKKMAPPPK
K16 KTHGESKKMAPPPKE
S28 PKEVEEDSEDEEMSE
S34 DSEDEEMSEDEDDSS
S40 MSEDEDDSSGEEEVV
S41 SEDEDDSSGEEEVVI
G42 EDEDDSSGEEEVVIP
T59 KGKKATTTPAKKVVV
K62 KATTTPAKKVVVSQT
K63 ATTTPAKKVVVSQTK
S67 PAKKVVVSQTKKAAV
T69 KKVVVSQTKKAAVPT
K70 KVVVSQTKKAAVPTP
K71 VVVSQTKKAAVPTPA
T76 TKKAAVPTPAKKAAV
K79 AAVPTPAKKAAVTPG
K80 AVPTPAKKAAVTPGK
T84 PAKKAAVTPGKKAAA
K87 KAAVTPGKKAAATPA
K88 AAVTPGKKAAATPAK
T92 PGKKAAATPAKKAVT
K95 KAAATPAKKAVTPAK
T99 TPAKKAVTPAKVVPT
K102 KKAVTPAKVVPTPGK
P105 VTPAKVVPTPGKKGA
T106 TPAKVVPTPGKKGAA
K109 KVVPTPGKKGAAQAK
K110 VVPTPGKKGAAQAKA
A113 TPGKKGAAQAKALVP
K116 KKGAAQAKALVPTPG
T121 QAKALVPTPGKKGAV
K124 ALVPTPGKKGAVTPA
K125 LVPTPGKKGAVTPAK
K132 KGAVTPAKGAKNGKN
K135 VTPAKGAKNGKNAKK
S145 KNAKKEDSDEDEDEE
- under review  
- under review  
S187 AAPAAPASEDEDEED
S214 EEEEEDDSEEEVMEI
I221 SEEEVMEITPAKGKK
T222 EEEVMEITPAKGKKT
S306 KKQKIEGSEPTTPFN
T309 KIEGSEPTTPFNLFI
T310 IEGSEPTTPFNLFIG
K323 IGNLNPNKSVAELKV
K323 IGNLNPNKSVAELKV
K329 NKSVAELKVAISELF
K338 AISELFAKNDLAAVD
K338 AISELFAKNDLAAVD
T348 LAAVDVRTGTNRKFG
T350 AVDVRTGTNRKFGYV
K353 VRTGTNRKFGYVDFE
S361 FGYVDFESAEDLEKA
T372 LEKALELTGLKVFGN
K375 ALELTGLKVFGNEIK
K375 ALELTGLKVFGNEIK
K382 KVFGNEIKLEKPKGR
K392 KPKGRDSKKVRAART
K403 AARTLLAKNLSFNIT
K403 AARTLLAKNLSFNIT
S406 TLLAKNLSFNITEDE
F407 LLAKNLSFNITEDEL
N408 LAKNLSFNITEDELK
N408 LAKNLSFNITEDELK
T410 KNLSFNITEDELKEV
K415 NITEDELKEVFEDAV
S428 AVEIRLVSQDGRSKG
S433 LVSQDGRSKGIAYIE
K449 KSEADAEKNLEEKQG
K454 AEKNLEEKQGAEIDG
K454 AEKNLEEKQGAEIDG
S463 GAEIDGRSVSLYYTG
S465 EIDGRSVSLYYTGEK
Y467 DGRSVSLYYTGEKGQ
Y468 GRSVSLYYTGEKGQR
T469 RSVSLYYTGEKGQRQ
K472 SLYYTGEKGQRQERT
K472 SLYYTGEKGQRQERT
- under review  
K481 QRQERTGKNSTWSGE
T491 TWSGESKTLVLSNLS
S498 TLVLSNLSYSATEET
T502 SNLSYSATEETLQEV
E503 NLSYSATEETLQEVF
K512 TLQEVFEKATFIKVP
K517 FEKATFIKVPQNPHG
K517 FEKATFIKVPQNPHG
K525 VPQNPHGKSKGYAFI
K527 QNPHGKSKGYAFIEF
Y529 PHGKSKGYAFIEFAS
S536 YAFIEFASFEDAKEA
K541 FASFEDAKEALNSCN
K549 EALNSCNKMEIEGRT
K549 EALNSCNKMEIEGRT
R565 RLELQGPRGSPNARS
S567 ELQGPRGSPNARSQP
K576 NARSQPSKTLFVKGL
K576 NARSQPSKTLFVKGL
K581 PSKTLFVKGLSEDTT
K581 PSKTLFVKGLSEDTT
S584 TLFVKGLSEDTTEET
K593 DTTEETLKESFEGSV
T606 SVRARIVTDRETGSS
R608 RARIVTDRETGSSKG
K614 DRETGSSKGFGFVDF
S623 FGFVDFNSEEDAKAA
K631 EEDAKAAKEAMEDGE
T645 EIDGNKVTLDWAKPK
K650 KVTLDWAKPKGEGGF
R660 GEGGFGGRGGGRGGF
R660 GEGGFGGRGGGRGGF
R664 FGGRGGGRGGFGGRG
R664 FGGRGGGRGGFGGRG
R670 GRGGFGGRGGGRGGR
R674 FGGRGGGRGGRGGFG
R677 RGGGRGGRGGFGGRG
R683 GRGGFGGRGRGGFGG
R685 GGFGGRGRGGFGGRG
R685 GGFGGRGRGGFGGRG
R691 GRGGFGGRGGFRGGR
R691 GRGGFGGRGGFRGGR
R695 FGGRGGFRGGRGGGG
R698 RGGFRGGRGGGGDFK
R698 RGGFRGGRGGGGDFK
K709 GDFKPQGKKTKFE__
T711 FKPQGKKTKFE____
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