a protein of the ubiquitin-activating E1 family. Acts as a UBL1 E1 ligase. Mediates ATP-dependent activation of UBL1 and formation of a thiolester with a conserved cysteine residue on SAE2. Note: This description may include information from UniProtKB.
Protein type: EC 6.3.2.-; Ubiquitin ligase; Ligase; Motility/polarity/chemotaxis; EC 22.214.171.124; Ubiquitin conjugating system
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: SUMO activating enzyme activity; protein binding; protein heterodimerization activity; metal ion binding; enzyme activator activity; transcription factor binding; ATP binding; ligase activity
Biological Process: positive regulation of catalytic activity; cellular protein metabolic process; protein sumoylation; post-translational protein modification
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.