eukaryotic translation initiation factor 3 subunit 4. Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. This subunit binds to the 18S rRNA. eIF-3 is composed of at least 12 different subunits. Contains 1 RNA recognition motif (RRM) domain. Note: This description may include information from UniProtKB.
Protein type: Translation; Translation initiation
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: eukaryotic translation initiation factor 3 complex; perinuclear region of cytoplasm; cytoplasm; cytosol; nucleus
Molecular Function: protein binding; translation initiation factor activity; nucleotide binding
Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.