Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Homodimer; disulfide-linked. Belongs to the 5'-nucleotidase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Phosphatase (non-protein); EC 188.8.131.52; Membrane protein, GPI anchor; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.