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Protein Page:
MMP10 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
MMP10 Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Belongs to the peptidase M10A family. Note: This description may include information from UniProtKB.
Protein type: Protease; Secreted; Extracellular matrix; EC 3.4.24.22; Secreted, signal peptide
Cellular Component: proteinaceous extracellular matrix; extracellular space; extracellular region
Molecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion binding
Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; proteolysis; regulation of cell migration
Reference #:  P09238 (UniProtKB)
Alt. Names/Synonyms: matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP-10; MMP10; SL-2; STMY2; stromelysin 2; Stromelysin-2; transin 2; Transin-2
Gene Symbols: MMP10
Molecular weight: 54,151 Da
Basal Isoelectric point: 5.49  Predict pI for various phosphorylation states
CST Pathways:  Angiogenesis  |  GPCR Signaling to MAPKs
Select Structure to View Below

MMP10

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K54-a DVKQFRRkDSNLIVK
0 2 S281-p VPTKSVPsGSEMPAK
  mouse

 
K55 EKQIFKRKDSSPVVK
- under review  
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