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MYO6 (human)

Overview MYO6 a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins. Note: This description may include information from UniProtKB. Protein type: Actin binding protein; Motility/polarity/chemotaxis; Motor protein Cellular Component: Golgi apparatus; nuclear membrane; microvillus; cytoplasmic membrane-bound vesicle; clathrin coated vesicle membrane; coated pit; cell cortex; clathrin-coated endocytic vesicle; DNA-directed RNA polymerase II, holoenzyme; cytosol; nucleoplasm; filamentous actin; ruffle; cell soma; axon; perinuclear region of cytoplasm; endocytic vesicle; apical part of cell; cytoplasm; unconventional myosin complex; plasma membrane; nucleus Molecular Function: calmodulin binding; actin filament binding; minus-end directed microfilament motor activity; protein binding; motor activity; actin binding; ADP binding; ATP binding Biological Process: response to drug; inner ear morphogenesis; DNA damage response, signal transduction by p53 class mediator; actin filament-based movement; regulation of synaptic plasticity; auditory receptor cell differentiation; regulation of secretion; endocytosis; locomotory behavior; synaptic transmission; intracellular protein transport; synaptogenesis; sensory perception of sound; glutamate secretion; dendrite development; positive regulation of transcription from RNA polymerase II promoter; protein targeting Reference #:  Q9UM54 (UniProtKB) Alt. Names/Synonyms: DFNA22; DFNB37; KIAA0389; MYO6; myosin VI; Myosin-VI; Unconventional myosin-6 Gene Symbols: MYO6 Molecular weight: 149,691 Da Basal Isoelectric point: 8.74  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below MYO6 2KIA - A=1137-1265 (mouse) 3H8D - A/D/C/B=1137-1265 (mouse) 2BKH - A=2-816 (pig) 2BKI - A=1-859 (pig) 2V26 - A=379-789 (pig) 2VAS - A=379-816 (pig) 2VB6 - A=379-816 (pig) 2X51 - A=304-816 (pig) 3GN4 - A/E=771-918 (pig) 3L9I - A=2-816 (pig) 4ANJ - A=1-817 (pig)

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  DISEASE 600970 606346  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human ► Hide Isoforms
0	1		K37	TIEPLNQKGKTFLAL
0	1		K56-a	FPAEEDSkkDVEDNC
0	2		K57-a	PAEEDSkkDVEDNCS
0	2		K78-u	ATLLHNIkVRYSKDR
0	1		T88-p	YSKDRIYtYVANILI
0	2		Y100-p	ILIAVNPyFDIPKIY
0	1		Y107	yFDIPKIYssEAIKS
0	1		S108-p	FDIPKIYssEAIKSY
0	1		S109-p	DIPKIYssEAIKSYQ
0	1		Y167-p	NTKFVLRyLTESYGT
0	5		K196-u	LEAFGNAkTVRNNNS
0	3		S267-p	REKLHLSsPDNFRYL
0	1		K285	CTRYFANKETDKQIL
0	1		S297-p	QILQNRKsPEyLKAG
0	2		Y300-p	QNRKsPEyLKAGSMK
0	1		K326-a	RMCTAMKkIGLDDEE
0	6		K334-a	IGLDDEEkLDLFRVV
3	5		T405-p	TAGGTKGtVIKVPLK
0	1		K408	GTKGtVIKVPLKVEQ
0	1		K412	tVIKVPLKVEQANNA
0	2		K425-u	NARDALAkTVYSHLF
0	1		K490-u	FFNERILkEEQELYQ
0	1		S539	ENRLPQPSDQHFTSA
0	1		T544	QPSDQHFTSAVHQKH
0	1		S545	PSDQHFTSAVHQKHK
0	1		S604	NNDALHMSLESLICE
0	3		K629-u	ESSTNNNkDTkQKAG
0	3		K632-u	TNNNkDTkQKAGKLs
0	1		S639-p	kQKAGKLsFISVGNk
0	3		K646-u	sFISVGNkFkTQLNL
0	1		K648-u	ISVGNkFkTQLNLLL
0	1		S660-p	LLLDKLRstGAsFIR
0	1		T661-p	LLDKLRstGAsFIRC
0	1		S664-p	KLRstGAsFIRCIKP
0	1		K750-u	GLNENDYkFGLTkVF
0	4		K755-u	DYkFGLTkVFFRPGK
0	1		K782-u	DHLAELVkRVNHWLT
0	2		K795-u	LTCSRWKkVQWCSLS
0	1		T845-p	DGLVKVGtLKKRLDK
0	1		K852	tLKKRLDKFNEVVSV
0	1		K886-u	DTLMAKIkSTMMTQE
0	1		K897-u	MTQEQIQkEYDALVK
0	1		S911-p	KSSEELLsALQkKKQ
0	2		K915-u	ELLsALQkKKQQEEE
0	14		K993-u	EAQLARQkEEESQQQ
0	1		S1025	QSEAELISDEAQADL
0	37		K1076-u	GPAVLATkAAAGTkK
0	2		K1082-u	TkAAAGTkKYDLSKW
0	1		K1090-u	KYDLSKWkYAELRDT
0	27		K1119-u	EEFHRRLkVyHAWkS
0	37		Y1121-p	FHRRLkVyHAWkSKN
0	2		K1125-u	LkVyHAWkSKNKKRN
0	23		K1141-u	ETEQRAPkSVtDyDF
0	1		T1144-p	QRAPkSVtDyDFAPF
0	19		Y1146-p	APkSVtDyDFAPFLN
0	2		S1155	FAPFLNNSPQQNPAA
0	10		Y1191-p	FIRPADQykDPQskK
0	10		K1192-u	IRPADQykDPQskKK
0	1		S1196-p	DQykDPQskKKGWWY
0	1		K1197-u	QykDPQskKKGWWYA
0	1		T1283-p	ESRQARPtyATAMLQ
0	2		Y1284-p	SRQARPtyATAMLQS
0	2		K1294-u	AMLQSLLk_______

	MYO6 iso4
K37	TIEPLNQKGKTFLAL
K56	FPAEEDSKKDVEDNC
K57	PAEEDSKKDVEDNCS
K78	ATLLHNIKVRYSKDR
T88	YSKDRIYTYVANILI
Y100	ILIAVNPYFDIPKIY
Y107	YFDIPKIYSSEAIKS
S108	FDIPKIYSSEAIKSY
S109	DIPKIYSSEAIKSYQ
Y167	NTKFVLRYLTESYGT
K196	LEAFGNAKTVRNNNS
S267	REKLHLSSPDNFRYL
K285	CTRYFANKETDKQIL
S297	QILQNRKSPEYLKAG
Y300	QNRKSPEYLKAGSMK
K326	RMCTAMKKIGLDDEE
K334	IGLDDEEKLDLFRVV
T405	TAGGTKGTVIKVPLK
K408	GTKGTVIKVPLKVEQ
K412	TVIKVPLKVEQANNA
K425	NARDALAKTVYSHLF
K490	FFNERILKEEQELYQ
S539	ENRLPQPSDQHFTSA
T544	QPSDQHFTSAVHQKH
S545	PSDQHFTSAVHQKHK
S604	NNDALHMSLESLICE
K629	ESSTNNNKDTKQKAG
K632	TNNNKDTKQKAGKLS
S639	KQKAGKLSFISVGNK
K646	SFISVGNKFKTQLNL
K648	ISVGNKFKTQLNLLL
S660	LLLDKLRSTGASFIR
T661	LLDKLRSTGASFIRC
S664	KLRSTGASFIRCIKP
K750	GLNENDYKFGLTKVF
K755	DYKFGLTKVFFRPGK
K782	DHLAELVKRVNHWLT
K795	LTCSRWKKVQWCSLS
T845	DGLVKVGTLKKRLDK
K852	TLKKRLDKFNEVVSV
K886	DTLMAKIKSTMMTQE
K897	MTQEQIQKEYDALVK
S911	KSSEELLSALQKKKQ
K915	ELLSALQKKKQQEEE
K993	EAQLARQKEEESQQQ
S1025	QSEAELISDEAQADL
K1076	GPAVLATKAAAGTKK
K1082	TKAAAGTKKYDLSKW
K1090	KYDLSKWKYAELRDT
K1119	EEFHRRLKVYHAWKS
Y1121	FHRRLKVYHAWKSKN
K1125	LKVYHAWKSKNKKRN
K1141-u	ETEQRAPkSVTDyPQ
T1144	QRAPkSVTDyPQQNP
Y1146-p	APkSVTDyPQQNPAA
-	gap
Y1182	FIRPADQYKDPQSKK
K1183	IRPADQYKDPQSKKK
S1187	DQYKDPQSKKKGWWY
K1188	QYKDPQSKKKGWWYA
T1274	ESRQARPTYATAMLQ
Y1275	SRQARPTYATAMLQS
K1285	AMLQSLLK_______

	MYO6 iso5
K37	TIEPLNQKGKTFLAL
K56	FPAEEDSKKDVEDNC
K57	PAEEDSKKDVEDNCS
K78	ATLLHNIKVRYSKDR
T88	YSKDRIYTYVANILI
Y100	ILIAVNPYFDIPKIY
Y107	YFDIPKIYSSEAIKS
S108	FDIPKIYSSEAIKSY
S109	DIPKIYSSEAIKSYQ
Y167	NTKFVLRYLTESYGT
K196	LEAFGNAKTVRNNNS
S267	REKLHLSSPDNFRYL
K285	CTRYFANKETDKQIL
S297	QILQNRKSPEYLKAG
Y300	QNRKSPEYLKAGSMK
K326	RMCTAMKKIGLDDEE
K334	IGLDDEEKLDLFRVV
T405	TAGGTKGTVIKVPLK
K408	GTKGTVIKVPLKVEQ
K412	TVIKVPLKVEQANNA
K425	NARDALAKTVYSHLF
K490	FFNERILKEEQELYQ
S539	ENRLPQPSDQHFTSA
T544	QPSDQHFTSAVHQKH
S545	PSDQHFTSAVHQKHK
S604	NNDALHMSLESLICE
K629	ESSTNNNKDTKQKAG
K632	TNNNKDTKQKAGKLS
S639	KQKAGKLSFISVGNK
K646	SFISVGNKFKTQLNL
K648	ISVGNKFKTQLNLLL
S660	LLLDKLRSTGASFIR
T661	LLDKLRSTGASFIRC
S664	KLRSTGASFIRCIKP
K750	GLNENDYKFGLTKVF
K755	DYKFGLTKVFFRPGK
K782	DHLAELVKRVNHWLT
K795	LTCSRWKKVQWCSLS
T845	DGLVKVGTLKKRLDK
K852	TLKKRLDKFNEVVSV
K886	DTLMAKIKSTMMTQE
K897	MTQEQIQKEYDALVK
S911	KSSEELLSALQKKKQ
K915	ELLSALQKKKQQEEE
K993	EAQLARQKEEESQQQ
S1025	QSEAELISDEAQADL
K1044	GPAVLATKAAAGTKK
K1050	TKAAAGTKKYDLSKW
K1058	KYDLSKWKYAELRDT
K1087	EEFHRRLKVyHAWKS
Y1089-p	FHRRLKVyHAWKSKN
K1093	LKVyHAWKSKNKKRN
K1109-u	ETEQRAPkSVTDyPQ
T1112	QRAPkSVTDyPQQNP
Y1114-p	APkSVTDyPQQNPAA
-	gap
Y1150	FIRPADQYKDPQSKK
K1151	IRPADQYKDPQSKKK
S1155	DQYKDPQSKKKGWWY
K1156	QYKDPQSKKKGWWYA
T1242	ESRQARPTYATAMLQ
Y1243	SRQARPTYATAMLQS
K1253	AMLQSLLK_______

	mouse ► Hide Isoforms
K37-u	TIEPLNQkGKTFGAL
K56	FPAEEDSKKDVEDNC
K57	PAEEDSKKDVEDNCS
K78-u	ATLLHNVkVRYSKDR
T88	YSKDRIYTYVANILI
Y100	ILIAVNPYFDIPKIY
Y107	YFDIPKIYSSDTIKS
S108	FDIPKIYSSDTIKSY
S109	DIPKIYSSDTIKSYQ
I167	NTKFGSKIPDRILWT
K196-u	LEAFGNAkTVRNNNS
S267-p	REKLHLSsPDNFRYL
K285-u	CTRFFANkETDKQIL
S297	QILQNRKSPEYVKAG
Y300	QNRKSPEYVKAGSLE
K326	QDVHSHEKNWFGMMK
K334	NWFGMMKKNFDLFRV
T406-p	TAGGTKGtVIkVPLk
K409-u	GTKGtVIkVPLkVEQ
K413-u	tVIkVPLkVEQANNA
K426-u	NARDALAkTVYSHLF
K491	FFNERILKEEQELYQ
S540-p	ENRLPQPsDQHFtsV
T545-p	QPsDQHFtsVVHQKH
S546-p	PsDQHFtsVVHQKHK
S607-p	NNDALHMsLESLICE
K632	ESSTNNSKDTKQKAG
K635	TNNSKDTKQKAGKLs
S642-p	KQKAGKLsFISVGNk
K649-u	sFISVGNkFKTQLNL
K651	ISVGNkFKTQLNLLL
S663	LLLDKLRSTGASFIR
T664	LLDKLRSTGASFIRC
S667	KLRSTGASFIRCIKP
K753	GLNEVDYKFGLTQVF
Q758	DYKFGLTQVFFRPGK
K785	DHLAELVKRVNLWLV
K798	LVCSRWKKVQWCSLS
T848	DGLVKVGTLKKRLDk
K855-u	TLKKRLDkFNEVVSA
T889	DALMAKFTSTMMTRE
K900	MTREQIQKEYDALVK
S914	KSSEDLLSALQkKKQ
K918-u	DLLSALQkKKQQEEE
R996	EAQLARQREEESQQQ
S1028-p	QNESELIsDEAQGDM
K1047	GPAVQATKAASGTKK
K1053	TKAASGTKKHDLSKW
K1061	KHDLSKWKYAELRDT
K1090-u	EEFHRRLkVYHAWkS
Y1092	FHRRLkVYHAWkSKN
K1096-u	LkVYHAWkSKNKKRN
K1112-u	ETEQRAPkSVTDYDF
T1115	QRAPkSVTDYDFAPF
Y1117	APkSVTDYDFAPFLN
S1126-p	FAPFLNNsPQQNPAA
Y1162	FIRPADQYKDPQNKK
K1163	IRPADQYKDPQNKKK
N1167	DQYKDPQNKKKGWWY
K1168	QYKDPQNKKKGWWYA
T1254	ESRQARPTYATAMLQ
Y1255	SRQARPTYATAMLQN
K1265	AMLQNLLK_______

	MYO6 iso6
K37	TIEPLNQKGKTFLAL
K56	FPAEEDSKKDVEDNC
K57	PAEEDSKKDVEDNCS
K78	ATLLHNVKVRYSKDR
T88	YSKDRIYTYVANILI
Y100	ILIAVNPYFDIPKIY
Y107	YFDIPKIYSSDTIKS
S108	FDIPKIYSSDTIKSY
S109	DIPKIYSSDTIKSYQ
Y167	NTKFVLRYLTESYGT
K196	LEAFGNAKTVRNNNS
S267	REKLHLSSPDNFRYL
K285	CTRFFANKETDKQIL
S297	QILQNRKSPEYVKAG
Y300	QNRKSPEYVKAGSLK
K326	RMCTAMKKIGLDDEE
K334	IGLDDEEKLDLFRVV
T405	TAGGTKGTVIKVPLK
K408	GTKGTVIKVPLKVEQ
K412	TVIKVPLKVEQANNA
K425	NARDALAKTVYSHLF
K490	FFNERILKEEQELYQ
S539	ENRLPQPSDQHFTSV
T544	QPSDQHFTSVVHQKH
S545	PSDQHFTSVVHQKHK
S604	NNDALHMSLESLICE
K629-u	ESSTNNNkDTkQKAG
K632-u	TNNNkDTkQKAGKLS
S639	kQKAGKLSFISVGNK
K646	SFISVGNKFKTQLNL
K648	ISVGNKFKTQLNLLL
S660	LLLDKLRSTGASFIR
T661	LLDKLRSTGASFIRC
S664	KLRSTGASFIRCIKP
K750	GLNEVDYKFGLTKVF
K755	DYKFGLTKVFFRPGK
K782	DHLAELVKRVNLWLV
K795	LVCSRWKKVQWCSLS
T845	DGLVKVGTLKKRLDK
K852	TLKKRLDKFNEVVSA
K886	DALMAKIKSTMMTRE
K897	MTREQIQKEYDALVK
S911	KSSEDLLSALQKKKQ
K915	DLLSALQKKKQQEEE
R993	EAQLARQREEESQQQ
S1025	QNESELISDEAQGDM
K1044-u	GPAVQATkAAAGTKK
K1050	TkAAAGTKKHDLSKW
K1058	KHDLSKWKYAELRDT
K1087	EEFHRRLKVYHAWKS
Y1089	FHRRLKVYHAWKSKN
K1093	LKVYHAWKSKNKKRN
K1109	ETEQRAPKSVTDYDF
T1112	QRAPKSVTDYDFAPF
Y1114	APKSVTDYDFAPFLN
S1123	FAPFLNNSPQQNPAA
Y1159	FIRPADQYKDPQNKK
K1160	IRPADQYKDPQNKKK
N1164	DQYKDPQNKKKGWWY
K1165	QYKDPQNKKKGWWYA
T1251	ESRQARPTYATAMLQ
Y1252	SRQARPTYATAMLQN
K1262	AMLQNLLK_______

	MYO6 iso7
K37	TIEPLNQKGKTFLAL
K56	FPAEEDSKKDVEDNC
K57	PAEEDSKKDVEDNCS
K78	ATLLHNVKVRYSKDR
T88	YSKDRIYTYVANILI
Y100	ILIAVNPYFDIPKIY
Y107	YFDIPKIYSSDTIKS
S108	FDIPKIYSSDTIKSY
S109	DIPKIYSSDTIKSYQ
Y167	NTKFVLRYLTESYGT
K196	LEAFGNAKTVRNNNS
S267	REKLHLSSPDNFRYL
K285	CTRFFANKETDKQIL
S297	QILQNRKSPEYVKAG
Y300	QNRKSPEYVKAGSLK
K326	RMCTAMKKIGLDDEE
K334	IGLDDEEKLDLFRVV
T405	TAGGTKGTVIKVPLK
K408	GTKGTVIKVPLKVEQ
K412	TVIKVPLKVEQANNA
K425	NARDALAKTVYSHLF
K490	FFNERILKEEQELYQ
S539	ENRLPQPSDQHFTSV
T544	QPSDQHFTSVVHQKH
S545	PSDQHFTSVVHQKHK
S604	NNDALHMSLESLICE
K629-u	ESSTNNNkDTkQKAG
K632-u	TNNNkDTkQKAGKLS
S639	kQKAGKLSFISVGNK
K646	SFISVGNKFKTQLNL
K648	ISVGNKFKTQLNLLL
S660	LLLDKLRSTGASFIR
T661	LLDKLRSTGASFIRC
S664	KLRSTGASFIRCIKP
K750	GLNEVDYKFGLTKVF
K755	DYKFGLTKVFFRPGK
K782	DHLAELVKRVNLWLV
K795	LVCSRWKKVQWCSLS
T845	DGLVKVGTLKKRLDK
K852	TLKKRLDKFNEVVSA
K886	DALMAKIKSTMMTRE
K897	MTREQIQKEYDALVK
S911	KSSEDLLSALQKKKQ
K915	DLLSALQKKKQQEEE
R993	EAQLARQREEESQQQ
S1025	QNESELISDEAQGDM
K1057-u	GPAVQATkAAAGTKK
K1063	TkAAAGTKKHDLSKW
K1071	KHDLSKWKYAELRDT
K1100	EEFHRRLKVYHAWKS
Y1102	FHRRLKVYHAWKSKN
K1106	LKVYHAWKSKNKKRN
K1122-u	ETEQRAPkSVTDYAQ
T1125	QRAPkSVTDYAQQNP
Y1127	APkSVTDYAQQNPAA
-	gap
Y1163	FIRPADQYKDPQNKK
K1164	IRPADQYKDPQNKKK
N1168	DQYKDPQNKKKGWWY
K1169	QYKDPQNKKKGWWYA
T1255	ESRQARPTYATAMLQ
Y1256	SRQARPTYATAMLQN
K1266	AMLQNLLK_______

	rat
K37	TIEPLNQKGKTFLAL
K56	FPAEEDSKKDVEDNC
K57	PAEEDSKKDVEDNCS
K78	ATLLHNVKVRYSKDR
T88	YSKDRIYTYVANILI
Y100-p	ILIAVNPyFDIPKIy
Y107-p	yFDIPKIySSDTIKS
S108	FDIPKIySSDTIKSY
S109	DIPKIySSDTIKSYQ
Y167	NTKFVLRYLTESYGT
K196	LEAFGNAKTVRNNNS
S267	REKLHLSSPDNFRYL
K285	CTRYFANKETDKQIL
S297	QILQNRKSPEYVKAG
Y300	QNRKSPEYVKAGSLK
K326	RMCTAMKKIGLDDEE
K334-a	IGLDDEEkLDLFRVV
T405	TAGGTKGTVIKVPLK
K408	GTKGTVIKVPLKVEQ
K412	TVIKVPLKVEQANSA
K425	SARDALAKTVYSHLF
K490	FFNERILKEEQELYQ
S539	ENRLPQPSDQHFTSV
T544	QPSDQHFTSVVHQKH
S545	PSDQHFTSVVHQKHK
S604	NNDALHMSLESLICE
K629	ESSTNNNKDTKQKAG
K632	TNNNKDTKQKAGKLS
S639	KQKAGKLSFISVGNK
K646	SFISVGNKFKTQLNL
K648	ISVGNKFKTQLNLLL
S660	LLLDKLRSTGASFIR
T661	LLDKLRSTGASFIRC
S664	KLRSTGASFIRCIKP
K750	GLNEVDYKFGLTKVF
K755	DYKFGLTKVFFRPGK
K782	DHLAELVKRVNLWLV
K795	LVCSRWKKVQWCSLS
T845	DGLVKVGTLKKRLDK
K852	TLKKRLDKFNEVVSA
K886	DALMAKIKSTMMTRE
K897	MTREQIQKEYDALVK
S911	KSSEDLLSALQKKKQ
K915	DLLSALQKKKQQEEE
R993	EAQLARQREEESQQQ
S1025	QNESELISDEAQGDT
K1044-u	GPAVQATkAAAGTKK
K1050	TkAAAGTKKHDLSKW
K1058	KHDLSKWKYAELRDT
K1087	EEFHRRLKVYHAWKS
Y1089	FHRRLKVYHAWKSKN
K1093	LKVYHAWKSKNKKRN
K1109-u	ETEQRAPkSVTDYDF
T1112	QRAPkSVTDYDFAPF
Y1114	APkSVTDYDFAPFLN
S1123	FAPFLNNSPQQNPAA
Y1159	FIRPADQYKDPQNKK
K1160	IRPADQYKDPQNKKK
N1164	DQYKDPQNKKKGWWY
K1165	QYKDPQNKKKGWWYA
T1251	ESRQARPTYATAMLQ
Y1252	SRQARPTYATAMLQN
K1262	AMLQNLLK_______

	pig
K37	TIEPLNQKGKTFLAL
K56	FPAEEDSKKDVEDNC
K57	PAEEDSKKDVEDNCS
K78	ATLLHNIKVRYSKDR
T88	YSKDRIYTYVANILI
Y100	ILIAVNPYFDIPKIY
Y107	YFDIPKIYSSETIKS
S108	FDIPKIYSSETIKSY
S109	DIPKIYSSETIKSYQ
Y167	NTKFVLRYLTESYGT
K196	LEAFGNAKTVRNNNS
S267	RERLHLSSPDNFRYL
K285	CTRYFANKETDKQIL
S297	QILQNRKSPEYLKAG
Y300	QNRKSPEYLKAGSLK
K326	RMCTAMKKIGLDDEE
K334	IGLDDEEKLDLFRVV
T406-p	TAGGAKGtVIKVPLK
K409	GAKGtVIKVPLKVEQ
K413	tVIKVPLKVEQANNA
K426	NARDALAKTVYSHLF
K491	FFNERILKEEQELYQ
S540	ENRLPQPSDQHFTSA
T545	QPSDQHFTSAGHQKH
S546	PSDQHFTSAGHQKHK
S605	NNDALHMSLESLICE
K630	ESSTNNNKDTKQKAG
K633	TNNNKDTKQKAGKLS
S640	KQKAGKLSFISVGNK
K647	SFISVGNKFKTQLNL
K649	ISVGNKFKTQLNLLL
S661	LLLDKLRSTGASFIR
T662	LLDKLRSTGASFIRC
S665	KLRSTGASFIRCIKP
K751	GLNEIDYKFGLTKVF
K756	DYKFGLTKVFFRPGK
K783	DHLAELVKRVNHWLI
K796	LICSRWKKVQWCSLS
T846	DGLVKVGTLKKRLDK
K853	TLKKRLDKFNEVVSA
K887	DALMAKIKSTMMTRE
K898	MTREQIQKEYDALVK
S912	KSSAVLLSALQKKKQ
K916	VLLSALQKKKQQEEE
R994	EAQLARQREEESQQQ
S1026	QSEAELISDEAQADP
K1045	GPAVQATKAAAGTKK
K1051	TKAAAGTKKYDLSKW
K1059	KYDLSKWKYAELRDT
K1088	EEFHRRLKVYHAWKS
Y1090	FHRRLKVYHAWKSKN
K1094	LKVYHAWKSKNKKRN
K1110	ETEQRAPKSVTDYAQ
T1113	QRAPKSVTDYAQQNP
Y1115	APKSVTDYAQQNPAV
-	gap
Y1151	FIRSADQYKDPQNKK
K1152	IRSADQYKDPQNKKK
N1156	DQYKDPQNKKKGWWY
K1157	QYKDPQNKKKGWWYA
T1243	ESRQARPTYATAMLQ
Y1244	SRQARPTYATAMLQN
K1254	AMLQNLLK_______

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