Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
Dcp1b (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
Dcp1b an mRNA decapping enzyme. Plays a role in regulating the mRNA degradation pathway. Note: This description may include information from UniProtKB.
Protein type: RNA binding protein; EC 3.-.-.-; Hydrolase
Cellular Component: intracellular membrane-bound organelle; cytoplasm; cytosol; nucleus
Molecular Function: protein binding; hydrolase activity
Biological Process: RNA metabolic process; mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA metabolic process; mRNA catabolic process, deadenylation-dependent decay
Reference #:  Q8IZD4 (UniProtKB)
Alt. Names/Synonyms: DCP1; DCP1 decapping enzyme homolog B (S. cerevisiae); DCP1B; decapping enzyme hDcp1b; hDcp1b; mRNA-decapping enzyme 1B
Gene Symbols: DCP1B
Molecular weight: 67,723 Da
Basal Isoelectric point: 8.75  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

Dcp1b

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  ENZYME  |  Source  |  InnateDB  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K89-u NRTEPITkDLDFQLQ
0 14 Y110-p RNARLSIyGIWFYDK
0 27 Y133-p LMKNLTQyEQLKAHQ
0 1 T142-p QLKAHQGtGAGIsPV
0 2 - gap
0 3 S147-p QGtGAGIsPVILNSG
0 1 Y172-p LIKAKDEyTKCKTCS
0 2 S186-p SEPKKITsSsAIyDN
0 3 S188-p PKKITsSsAIyDNPN
0 294 Y191-p ITsSsAIyDNPNLIK
0 6 S227-p DPEPQHLsLTALFGK
0 50 S275-p QGVVRSLsyEEPRRH
0 34 Y276-p GVVRSLsyEEPRRHs
0 11 S283-p yEEPRRHsPPIEKQL
0 18 T362-p LFEKLQStPGAANKC
0 29 T373-p ANKCDPStPAPASSA
0 1 T392-p SRAPTSVtPVAPGKG
0 3 S448-p TGSSGVIsPQELLKK
0 3 T504-p TPNTEQQtPLFQVIs
0 5 S511-p tPLFQVIsPQRIPAT
0 1 Y588-p QLQEALLyLIQNDDN
  mouse

 
K89 NRTEPITKDLDFQLQ
Y110 RNGTLSIYGIWFYDK
S133 LMKNLTQSEQLKACH
- gap
S144-p KACHGAGssPVTLSS
S145-p ACHGAGssPVTLSSG
Y170 LTKAKDEYTKCKTCS
N184 SEPKQMTNSSAICDN
S186 PKQMTNSSAICDNPK
C189 MTNSSAICDNPKLIK
S225 DPEPQHLSLTALFGK
S274 HGVACSLSCEEPRKL
C275 GVACSLSCEEPRKLs
S282-p CEEPRKLsLPVEKQL
- gap
- gap
T380 PTGPAVATQVAPGQS
- gap
- gap
- gap
N550 QLQEALLNLIQNDDN
  rat

 
K89 NRTEPITKDLDFQLQ
Y110 RNGTLSIYGIWFYDK
C133 LMKNLTQCEQLKACH
- gap
S146 CHGAGAGSSPVTLSS
S147 HGAGAGSSPVTLSSG
Y172 LTKAKDEYTKCRSCS
S186 SEPKQMTSSSAICDN
S188 PKQMTSSSAICDNPK
C191 MTSSSAICDNPKLIK
P227 DPEPQHLPLTALFGK
A277 HGVACSLACEDPRKL
C278 GVACSLACEDPRKLS
S285 CEDPRKLSLPVEKQL
- gap
- gap
T383 PASPAVTTQVAPGQS
- gap
- gap
- gap
N553 QLQEALLNLIQNDDN
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.