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Protein Page:
Dcp1b (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
Dcp1b an mRNA decapping enzyme. Plays a role in regulating the mRNA degradation pathway. Note: This description may include information from UniProtKB.
Protein type: RNA binding protein; Hydrolase; EC 3.-.-.-
Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleus; cytosol
Molecular Function: protein binding; hydrolase activity
Biological Process: RNA metabolic process; mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA catabolic process, deadenylation-dependent decay; mRNA metabolic process
Reference #:  Q8IZD4 (UniProtKB)
Alt. Names/Synonyms: DCP1; DCP1 decapping enzyme homolog B (S. cerevisiae); DCP1B; decapping enzyme hDcp1b; hDcp1b; mRNA-decapping enzyme 1B
Gene Symbols: DCP1B
Molecular weight: 67,723 Da
Basal Isoelectric point: 8.75  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

Dcp1b

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K89-ub NRTEPITkDLDFQLQ
0 14 Y110-p RNARLSIyGIWFYDK
0 27 Y133-p LMKNLTQyEQLKAHQ
0 1 T142-p QLKAHQGtGAGIsPV
0 2 I146 HQGtGAGIsPVILNS
0 5 S147-p QGtGAGIsPVILNSG
0 1 I150 GAGIsPVILNSGEGK
0 1 Y172-p LIKAKDEytKCKTCS
0 1 T173-p IKAKDEytKCKTCSE
0 2 S186-p SEPKKITsssAIyDN
0 1 S187-p EPKKITsssAIyDNP
0 3 S188-p PKKITsssAIyDNPN
0 280 Y191-p ITsssAIyDNPNLIK
0 6 S227-p DPEPQHLsLtALFGK
0 1 T229-p EPQHLsLtALFGKQD
0 52 S275-p QGVVRSLsyEEPRRH
0 34 Y276-p GVVRSLsyEEPRRHs
0 12 S283-p yEEPRRHsPPIEKQL
0 1 S336-p TGPVQPGsPHNIGTS
0 18 T362-p LFEKLQStPGAANKC
0 1 S372-p AANKCDPstPAPASS
0 27 T373-p ANKCDPstPAPASSA
0 1 S385-p SSAALNRsRAPTSVt
0 2 T392-p sRAPTSVtPVAPGKG
0 4 S448-p TGSSGVIsPQELLKK
0 3 T504-p TPNTEQQtPLFQVIs
0 5 S511-p tPLFQVIsPQRIPAT
0 1 Y588-p QLQEALLyLIQNDDN
  mouse

 
K89 NRTEPITKDLDFQLQ
Y110 RNGTLSIYGIWFYDK
S133 LMKNLTQSEQLKACH
- gap
S144-p KACHGAGssPVtLSS
S145-p ACHGAGssPVtLSSG
T148-p GAGssPVtLSSGEGQ
Y170 LTKAKDEYTKCKTCS
T171 TKAKDEYTKCKTCSE
N184 SEPKQMTNSSAICDN
S185 EPKQMTNSSAICDNP
S186 PKQMTNSSAICDNPK
C189 MTNSSAICDNPKLIK
S225 DPEPQHLSLTALFGK
T227 EPQHLSLTALFGKQD
S274 HGVACSLSCEEPRKL
C275 GVACSLSCEEPRKLs
S282-p CEEPRKLsLPVEKQL
S335 PGPVQLGSPWNGRVA
A361 LLEQLQGAPGAVHKY
C371 AVHKYNPCAPTGPAV
A372 VHKYNPCAPTGPAVA
- gap
T380 PTGPAVATQVAPGQS
T437 SSPTVLPTQELLRKL
A490 TASMEKQAPLLQSTC
- gap
N550 QLQEALLNLIQNDDN
  rat

 
K89 NRTEPITKDLDFQLQ
Y110 RNGTLSIYGIWFYDK
C133 LMKNLTQCEQLKACH
A142 QLKACHGAGAGSSPV
S146 CHGAGAGSSPVTLSS
S147 HGAGAGSSPVTLSSG
T150 GAGSSPVTLSSGEGR
Y172 LTKAKDEYTKCRSCS
T173 TKAKDEYTKCRSCSE
S186 SEPKQMTSSSAICDN
S187 EPKQMTSSSAICDNP
S188 PKQMTSSSAICDNPK
C191 MTSSSAICDNPKLIK
P227 DPEPQHLPLTALFGK
T229 EPQHLPLTALFGKQD
A277 HGVACSLACEDPRKL
C278 GVACSLACEDPRKLS
S285 CEDPRKLSLPVEKQL
A338 PGPVQLGAPWNGRAA
A364 LLEQLQGAPAAVHKY
C374 AVHKYSFCAPASPAV
A375 VHKYSFCAPASPAVT
- gap
T383 PASPAVTTQVAPGQS
T440 SSPTVLPTQELLRKL
A493 TASMEKQAPLLQSTC
- gap
N553 QLQEALLNLIQNDDN
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