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Protein Page:
ATG3 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
ATG3 an E2-like enzyme essential for Apg8p lipidation. Note: This description may include information from UniProtKB.
Protein type: Enzyme, cellular metabolism; Ubiquitin conjugating system; EC 6.3.2.-; Autophagy
Cellular Component: cytoplasmic ubiquitin ligase complex; cytosol
Molecular Function: protein binding; enzyme binding; small conjugating protein ligase activity; APG8 conjugating enzyme activity; APG12 conjugating enzyme activity
Biological Process: protein ubiquitination; protein modification process; mitochondrial fragmentation during apoptosis; protein targeting to membrane; autophagic vacuole formation
Reference #:  Q9NT62 (UniProtKB)
Alt. Names/Synonyms: 2610016C12Rik; APG3; APG3 autophagy 3-like; APG3-like; APG3L; ATG3; ATG3 autophagy related 3 homolog (S. cerevisiae); autophagy Apg3p/Aut1p-like; Autophagy-related protein 3; DKFZp564M1178; FLJ22125; hApg3; MGC15201; PC3-96; Protein PC3-96
Gene Symbols: ATG3
Molecular weight: 35,864 Da
Basal Isoelectric point: 4.66  Predict pI for various phosphorylation states
CST Pathways:  Autophagy Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ATG3
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 K11 VINTVKGKALEVAEy
0 333 Y18-p KALEVAEyLtPVLKE
0 6 T20-p LEVAEyLtPVLKESK
0 1 K24 EyLtPVLKESKFKET
0 1 D104-ca IIEEDDGdGGWVDTy
0 6 Y111-p dGGWVDTyHNTGItG
0 2 T117-p TyHNTGItGITEAVK
0 1 K131 KEITLENKDNIRLQD
0 3 K185-u IVEACKAktDAGGED
0 1 T186-p VEACKAktDAGGEDA
0 5 K208-u DLYITYDkYYQTPRL
0 1 T244 SQDHVKKTVTIENHP
0 1 T246 DHVKKTVTIENHPHL
0 1 T313-p YDYTRHFtM______
  mouse

 
K11-u VINTVKGkALEVAEy
Y18-p kALEVAEyLTPVLkE
T20 LEVAEyLTPVLkESK
K24-u EyLTPVLkESKFKET
D104 IIEEDDGDGGWVDTY
Y111 DGGWVDTYHNTGITG
T117 TYHNTGITGITEAVK
K131-u KEITLESkDSIKLQD
K185 IVEACKAKADAGGED
A186 VEACKAKADAGGEDA
K208-u DLYITYDkYYQTPRL
T244-p SQDHVKKtVtIENHP
T246-p DHVKKtVtIENHPHL
T313 YDYTRHFTM______
  rat

 
K11 VINTVKGKALEVAEY
Y18 KALEVAEYLTPVLKE
T20 LEVAEYLTPVLKESK
K24 EYLTPVLKESKFKET
D104 IIEEDDGDGGWVDTY
Y111 DGGWVDTYHNTGITG
T117 TYHNTGITGITEAVK
K131 KEITLESKDSIKLQD
K185 IVEACKAKADAGGED
A186 VEACKAKADAGGEDA
K208 DLYITYDKYYQTPRL
T244 SQDHVKKTVTIENHP
T246 DHVKKTVTIENHPHL
T313 YDYTRHFTM______
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