a member of the non-receptor protein tyrosine phosphatase (PTP) family. Contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This gene was found to be expressed in brain, colon tissues, and several different tumor-derived cell lines. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor); EC 22.214.171.124
Chromosomal Location of Human Ortholog: 2q21.1
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; non-membrane spanning protein tyrosine phosphatase activity
Biological Process: protein amino acid dephosphorylation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.