Home

hnRNP A0 (human)

Overview hnRNP A0 a ubiquitously expressed heterogeneous nuclear ribonucleoprotein (hnRNP) of the A/B subfamily. hnRNPs are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. Has two repeats of RNA recognition motif domains (RRM), followed by a glycine-rich C-terminus. Note: This description may include information from UniProtKB. Protein type: RNA splicing; RNA binding protein Cellular Component: nucleoplasm; nucleolus; nucleus; ribonucleoprotein complex Molecular Function: RNA binding; nucleotide binding; AU-rich element binding; protein kinase binding Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; response to lipopolysaccharide; mRNA processing; inflammatory response Reference #:  Q13151 (UniProtKB) Alt. Names/Synonyms: Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0; HNRNPA0; HNRPA0; ROA0 Gene Symbols: HNRNPA0 Molecular weight: 30,841 Da Basal Isoelectric point: 9.34  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below hnRNP A0

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  DISEASE  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		S19-p	GGLNVQTsESGLRGH
0	14		K45-u	VVVNPQTkRsRCFGF
0	1		S47-p	VNPQTkRsRCFGFVt
0	1		T54-p	sRCFGFVtySNVEEA
0	1		Y55-p	RCFGFVtySNVEEAD
0	1		S68-p	ADAAMAAsPHAVDGN
0	1		T76-p	PHAVDGNtVELKRAV
1	3		S84-p	VELKRAVsREDSARP
0	2		K99-u	GAHAKVKkLFVGGLk
0	8		K106-u	kLFVGGLkGDVAEGD
0	20		K133-u	KAEIIADkQSGKKRG
0	1		R139	DkQSGKKRGFGFVyF
0	16		Y145-p	KRGFGFVyFQNHDAA
0	2		N148	FGFVyFQNHDAADKA
0	2		K159-u	ADKAAVVkFHPIQGH
0	562		Y180-p	AVPKEDIysGGGGGG
0	17		S181-p	VPKEDIysGGGGGGs
0	1		S188-p	sGGGGGGsrSSRGGR
0	1		-	gap
0	3		R189-m1	GGGGGGsrSSRGGRG
0	2		Y217-p	SKGGGGGyNSYGGYG
0	1		S219	GGGGGyNSYGGYGGG
0	1		Y220	GGGGyNSYGGYGGGG
0	1		Y231-p	GGGGGGGyNAyGGGG
0	1		Y234-p	GGGGyNAyGGGGGGS
0	1		Y265-p	YSQHQSSyGPMKsGG
0	1		S270-p	SSyGPMKsGGGGGGG
0	1		S279-p	GGGGGGGssWGGrSN
0	1		S280-p	GGGGGGssWGGrSNS
0	2		R284-m1	GGssWGGrSNSGPYr
0	25		R291-m1	rSNSGPYrGGYGGGG
0	40		R291-m2	rSNSGPYrGGYGGGG
0	1		S303-p	GGGGYGGsSF_____
0	1		S304	GGGYGGsSF______

	mouse
S19	GGLNVQTSESGLRGH
K45	VVVNPQTKRSRCFGF
S47	VNPQTKRSRCFGFVT
T54	SRCFGFVTYSNVEEA
Y55	RCFGFVTYSNVEEAD
S68	ADAAMAASPHAVDGN
T76	PHAVDGNTVELKRAV
S84-p	VELKRAVsREDSARP
K99-u	GAHAKVKkLFVGGLK
K106	kLFVGGLKGDVAEGD
K133-u	KAEIIADkQSGKKrG
R139-m1	DkQSGKKrGFGFVYF
Y145	KrGFGFVYFQsHDAA
S148-p	FGFVYFQsHDAADKA
K159	ADKAAVVKFHPIQGH
H180	AVPKEDIHAGGGGAr
A181	VPKEDIHAGGGGArA
A186	IHAGGGGArAARGGR
R187-m1	HAGGGGArAARGGRG
R190	GGGArAARGGRGGGR
Y224-p	GGGGGGGyNsyGGYG
S226-p	GGGGGyNsyGGYGGY
Y227-p	GGGGyNsyGGYGGYG
Y233	syGGYGGYGAYGGGG
Y236	GYGGYGAYGGGGGGG
Y268	YSQHQSSYGPMKSGG
S273	SSYGPMKSGGGGGGG
S282	GGGGGGGSWGGRSNS
-	gap
R286	GGGSWGGRSNSGPYr
R293-m1	RSNSGPYrGGYGGGY
R293-m2	RSNSGPYrGGYGGGY
G303	YGGGYGGGsF_____
S304-p	GGGYGGGsF______

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E Produced by 3rd Millennium  |  Design by Digizyme ©2003-2013 Cell Signaling Technology, Inc.