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Protein Page:
4E-BP2 (human)

Overview
4E-BP2 eukaryotic translation initiation factor 4E binding protein 2 Note: This description may include information from UniProtKB.
Protein type: Translation initiation; Translation
Molecular Function: protein binding; eukaryotic initiation factor 4E binding
Biological Process: cAMP-mediated signaling; negative regulation of translational initiation; translation; insulin receptor signaling pathway
Reference #:  Q13542 (UniProtKB)
Alt. Names/Synonyms: 4E-BP2; 4EBP2; eIF4E-binding protein 2; EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2; Eukaryotic translation initiation factor 4E-binding protein 2; PHASII; phosphorylated, heat and acid stable regulated by insulin protein II
Gene Symbols: EIF4EBP2
Molecular weight: 12,939 Da
Basal Isoelectric point: 6.16  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

4E-BP2

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S4-p ____MSSsAGSGHQP
0 1 S25-p PTRTVAIsDAAQLPH
0 60 Y34-p AAQLPHDyCttPGGt
0 18 T36-p QLPHDyCttPGGtLF
1 64 T37-p LPHDyCttPGGtLFs
0 11 T41-p yCttPGGtLFsttPG
0 17 S44-p tPGGtLFsttPGGtR
0 15 T45-p PGGtLFsttPGGtRI
1 87 T46-p GGtLFsttPGGtRII
0 7 T50-p FsttPGGtRIIyDRK
0 4 Y54-p PGGtRIIyDRKFLLD
0 9 S65-p FLLDRRNsPMAQtPP
0 13 T70-p RNsPMAQtPPCHLPN
0 1 S83-p PNIPGVTsPGTLIED
4923 : Nonphospho-4E-BP1 (Thr46) (87D12) Rabbit mAb
  mouse

 
S4 ____MSASAGGSHQP
S25 PTRTVAISDAAQLPQ
Y34-p AAQLPQDyCttPGGt
T36-p QLPQDyCttPGGtLF
T37-p LPQDyCttPGGtLFs
T41-p yCttPGGtLFsttPG
S44-p tPGGtLFsttPGGtR
T45-p PGGtLFsttPGGtRI
T46-p GGtLFsttPGGtRII
T50-p FsttPGGtRIIyDRK
Y54-p PGGtRIIyDRKFLLD
S65-p FLLDRRNsPMAQtPP
T70-p RNsPMAQtPPCHLPN
S83 PNIPGVTSPGALIED
4923 : Nonphospho-4E-BP1 (Thr46) (87D12) Rabbit mAb
  rat

 
S4 ____MSASAGGGHQP
S25 PTRTVAISDAAQLPQ
Y34 AAQLPQDYCTtPGGT
T36 QLPQDYCTtPGGTLF
T37-p LPQDYCTtPGGTLFs
T41 YCTtPGGTLFsTtPG
S44-p tPGGTLFsTtPGGTR
T45 PGGTLFsTtPGGTRI
T46-p GGTLFsTtPGGTRII
T50 FsTtPGGTRIIYDRK
Y54 PGGTRIIYDRKFLLD
S65 FLLDRRNSPMAQTPP
T70 RNSPMAQTPPCHLPN
S83 PNIPGVTSPGALMED
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