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Protein Page:
FLNB (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
FLNB a ubiquitous cytoskeletal protein that links actin filaments to membrane glycoproteins. Six alternatively spliced isoforms have been described. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoforms 1 and 2 are expressed in placenta, bone marrow, brain, umbilical vein endothelial cells, retina and skeletal muscle. Isoform 1 is predominantly expressed in prostate, uterus, liver, thyroid, stomach, lymph node, small intestine, spleen, skeletal muscle, kidney, placenta, pancreas, heart, lung, platelets, endothelial cells, megakaryocytic and erythroleukemic cell lines. Isoform 2 is predominantly expressed in spinal cord and platelets. Also expressed in thyroid adenoma, neurofibrillary tangles (NFT), senile plaques in the hippocampus and cerebral cortex in Alzheimer's disease. Isoform 3 and isoform 6 are expressed predominantly in lung, heart, skeletal muscle, testis, spleen, thymus and leukocytes. Isoform 4 and isoform 5 are expressed in heart. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Actin binding protein
Cellular Component: focal adhesion; cytoplasm; stress fiber; plasma membrane; integral to membrane; cell cortex; Z disc; cytosol; actin cytoskeleton
Molecular Function: identical protein binding; protein binding; actin binding
Biological Process: skeletal muscle development; cytoskeletal anchoring; cytokine and chemokine mediated signaling pathway; cell differentiation; actin cytoskeleton organization and biogenesis; signal transduction
Reference #:  O75369 (UniProtKB)
Alt. Names/Synonyms: ABP-278; ABP-280; ABP-280 homolog; actin binding protein 278; Actin-binding-like protein; AOI; Beta-filamin; DKFZp686A1668; DKFZp686O033; Fh1; filamin 1 (actin-binding protein-280)-like; filamin B, beta; Filamin homolog 1; Filamin-3; Filamin-B; FLN-B; FLN1L; FLN3; FLNB; LRS1; SCT; TABP; TAP; Thyroid autoantigen; Truncated ABP; Truncated actin-binding protein
Gene Symbols: FLNB
Molecular weight: 278,164 Da
Basal Isoelectric point: 5.47  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

FLNB

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  Phospho3D  |  DISEASE  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 3 K15-a LAEDAPWkkIQQNTF
0 4 K16-u AEDAPWkkIQQNTFT
0 3 K60-u LLEVLSQkRMYRKYH
0 2 T267-p YGRGIEPtGNMVKQP
0 1 S346-p SKSPFEVsVDKAQGD
0 2 K492-a GELGVTMkGPkGLEE
0 1 K492 GELGVTMKGPkGLEE
0 3 K495-u GVTMkGPkGLEELVk
0 2 K502-u kGLEELVkQKDFLDG
0 2 Y511 KDFLDGVYAFEYYPs
0 6 S518-p YAFEYYPstPGRYSI
0 24 T519-p AFEYYPstPGRYSIA
0 1 T528-p GRYSIAItWGGHHIP
0 1 S537-p GGHHIPKsPFEVQVG
0 2 Y596-p PSQAKIEyNDQNDGS
0 1 S630-p DDEDIKDsPYMAFIH
0 1 T640-p MAFIHPAtGGYNPDL
0 2 S658-p YGPGLEKsGCIVNNL
0 4 K677-a VDPKDAGkAPLkIFA
0 16 K681-a DAGkAPLkIFAQDGE
0 1 K681-u DAGkAPLkIFAQDGE
0 1 K697 QRIDIQMKNRMDGTy
0 127 Y704-p KNRMDGTyACSytPV
0 3 Y708-p DGTyACSytPVKAIK
0 2 T709-p GTyACSytPVKAIKH
0 3 S730-p GGVNIPHsPyRVNIG
0 1 Y732-p VNIPHsPyRVNIGQG
0 2 S740-p RVNIGQGsHPQKVKV
0 6 S833-p ASQEIPAsPFRVKVD
0 2 S886-p PLNVQFNsPLPGDAV
0 1 Y902-p DLDIIDNyDySHTVK
0 19 Y904-p DIIDNyDySHTVKYT
0 2 S932-p GGDPIPKsPFTVGVA
0 1 T965-p VGKDQEFtVDtRGAG
0 1 T968-p DQEFtVDtRGAGGQG
0 2 T980-p GQGKLDVtILsPSRK
0 11 S983-p KLDVtILsPSRKVVP
0 1 Y1020-p LYAVDVTydGHPVPG
0 1 D1021-ca YAVDVTydGHPVPGs
0 2 S1028-p dGHPVPGsPYTVEAS
1 0 K1147-u GPGLEHGkVGEAGLL
0 1 S1181-p SGTKAEVsIQNNKDG
0 1 T1198-p AVTYVPLtAGMYtLT
0 1 T1203-p PLtAGMYtLTMKYGG
0 1 K1241 FGPGIEGKDVFREAT
0 1 T1259-p TVDSRPLtQVGGDHI
0 4 S1316-p DDVPIPNsPFKVAVT
0 1 K1339 QAQGPGLKEAFTNKP
0 1 Y1395 IPFAPGDYDVNITYG
0 1 S1422-p VKDVVDPsKVKIAGP
0 5 S1433-p IAGPGLGsGVRARVL
0 1 S1448-p QSFTVDSsKAGLAPL
0 1 D1476-ca VNVVDNGdGTHTVTY
0 18 S1505-p ADEEIPRsPFKVKVL
0 1 K1508 EIPRsPFKVKVLPTY
0 61 Y1530-p SGPGLSSyGVPAsLP
0 1 S1535-p SSyGVPAsLPVDFAI
0 1 T1557 GLLAVQITDQEGKPK
0 1 K1572 RAIVHDNKDGTyAVt
0 3 Y1576-p HDNKDGTyAVtYIPD
0 1 T1579-p KDGTyAVtYIPDKTG
0 1 S1602-p GGDDIPLsPYRIRAt
0 8 T1609-p sPYRIRAtQTGDASK
0 1 K1641 VGFVVDAKTAGKGKV
0 2 Y1684-p TAAKPGTyVIyVRFG
0 10 Y1687-p KPGTyVIyVRFGGVD
0 3 Y1733-p PWVTEEAyVPVSDMN
0 1 K1757-u VIPFAVRkGEITGEV
0 1 T1773-p MPSGKTAtPEIVDNK
0 1 K1780 tPEIVDNKDGtVtVR
0 1 T1783-p IVDNKDGtVtVRYAP
0 1 T1785-p DNKDGtVtVRYAPtE
0 1 T1791-p VtVRYAPtEVGLHEM
0 2 K1897-u ILVKYNDkHIPGSPF
0 1 S1916-p TDDSRRCsQVKLGsA
0 1 S1922-p CsQVKLGsAADFLLD
0 1 K1955-u RDEPCLLkRLPNNHI
0 1 R2010-m1 RRAKVYGrGLsEGRT
0 1 S2013-p KVYGrGLsEGRTFEM
0 1 S2036-p DAGYGGIsLAVEGPS
0 6 S2083-p ADEHVPGsPFtVKIS
0 1 T2086-p HVPGsPFtVKISGEG
0 1 K2088 PGsPFtVKISGEGRV
0 1 S2098-p GEGRVKEsITRtSRA
0 1 T2100 GRVKEsITRtSRAPs
0 2 T2102-p VKEsITRtSRAPsVA
0 12 S2107-p TRtSRAPsVATVGSI
0 1 S2135-p DMSAHVTsPSGRVTE
0 1 K2170-a GVHTVSVkYRGQHVT
0 1 T2239-p GPSKAEItFDDHKNG
0 1 Y2260-p IAQEPGNyEVSIKFN
0 1 Y2276-p EHIPESPyLVPVIAP
0 2 T2291-p SDDARRLtVMSLQEs
0 1 S2298-p tVMSLQEsGLKVNQP
0 1 S2325-p KIDAKVHsPSGAVEE
0 29 Y2343-p SELEPDKyAVRFIPH
0 6 S2369-p NGSHVVGsPFKVRVG
0 1 S2403-p GGTTGIQsEFFINTt
0 1 T2410-p sEFFINTtRAGPGTL
0 1 S2425-p SVTIEGPsKVKMDCQ
0 1 Y2438-p CQETPEGyKVMYTPM
0 1 S2453-p APGNYLIsVKYGGPN
0 1 Y2456 NYLIsVKYGGPNHIV
0 10 S2465-p GPNHIVGsPFKAKVt
0 1 T2472-p sPFKAKVtGQRLVsP
0 12 S2478-p VtGQRLVsPGsANET
0 4 S2481-p QRLVsPGsANETSsI
0 1 S2487-p GsANETSsILVESVT
0 2 T2500-p VTRSSTEtCysAIPK
0 838 Y2502-p RSSTEtCysAIPKAS
0 4 S2503-p SSTEtCysAIPKASs
0 1 S2510-p sAIPKASsDASKVTs
0 1 S2517-p sDASKVTsKGAGLSk
0 2 K2524-a sKGAGLSkAFVGQKS
0 2 K2524-u sKGAGLSkAFVGQKS
0 2 T2553-p LIGVHGPttPCEEVS
0 7 T2554-p IGVHGPttPCEEVSM
0 1 N2566 VSMKHVGNQQYNVTY
0 1 K2576-a YNVTYVVkERGDYVL
  FLNB iso8  
K15 LAEDAPWKKIQQNTF
K16 AEDAPWKKIQQNTFT
K60 LLEVLSQKRMYRKYH
T267 YGRGIEPTGNMVKQP
S346 SKSPFEVSVDKAQGD
K492 GELGVTMKGPKGLEE
K492 GELGVTMKGPKGLEE
K495 GVTMKGPKGLEELVK
K502 KGLEELVKQKDFLDG
Y511 KDFLDGVYAFEYYPS
S518 YAFEYYPSTPGRYSI
T519 AFEYYPSTPGRYSIA
T528 GRYSIAITWGGHHIP
S537 GGHHIPKSPFEVQVG
Y596 PSQAKIEYNDQNDGS
S630 DDEDIKDSPYMAFIH
T640 MAFIHPATGGYNPDL
S658 YGPGLEKSGCIVNNL
K677 VDPKDAGKAPLKIFA
K681 DAGKAPLKIFAQDGE
K681 DAGKAPLKIFAQDGE
K697 QRIDIQMKNRMDGTY
Y704 KNRMDGTYACSYTPV
Y708 DGTYACSYTPVKAIK
T709 GTYACSYTPVKAIKH
S730 GGVNIPHSPYRVNIG
Y732 VNIPHSPYRVNIGQG
S740 RVNIGQGSHPQKVKV
S833 ASQEIPASPFRVKVD
S886 PLNVQFNSPLPGDAV
Y902 DLDIIDNYDYSHTVK
Y904 DIIDNYDYSHTVKYT
S932 GGDPIPKSPFTVGVA
T965 VGKDQEFTVDTRGAG
T968 DQEFTVDTRGAGGQG
T980 GQGKLDVTILSPSRK
S983 KLDVTILSPSRKVVP
Y1020 LYAVDVTYDGHPVPG
D1021 YAVDVTYDGHPVPGS
S1028 DGHPVPGSPYTVEAS
K1147 GPGLEHGKVGEAGLL
S1181 SGTKAEVSIQNNKDG
T1198 AVTYVPLTAGMYTLT
T1203 PLTAGMYTLTMKYGG
K1241 FGPGIEGKDVFREAT
T1259 TVDSRPLTQVGGDHI
S1316 DDVPIPNSPFKVAVT
K1339 QAQGPGLKEAFTNKP
Y1395 IPFAPGDYDVNITYG
S1422 VKDVVDPSKVKIAGP
S1433 IAGPGLGSGVRARVL
S1448 QSFTVDSSKAGLAPL
D1507 VNVVDNGDGTHTVTY
S1536 ADEEIPRSPFKVKVL
K1539 EIPRSPFKVKVLPTY
Y1561 SGPGLSSYGVPASLP
S1566 SSYGVPASLPVDFAI
T1588 GLLAVQITDQEGKPK
K1603 RAIVHDNKDGTYAVT
Y1607 HDNKDGTYAVTYIPD
T1610 KDGTYAVTYIPDKTG
S1633 GGDDIPLSPYRIRAT
T1640 SPYRIRATQTGDASK
K1672 VGFVVDAKTAGKGKV
Y1715 TAAKPGTYVIYVRFG
Y1718 KPGTYVIYVRFGGVD
Y1764 PWVTEEAYVPVSDMN
K1788 VIPFAVRKGEITGEV
T1804 MPSGKTATPEIVDNK
K1811 TPEIVDNKDGTVTVR
T1814 IVDNKDGTVTVRYAP
T1816 DNKDGTVTVRYAPTE
T1822 VTVRYAPTEVGLHEM
K1928 ILVKYNDKHIPGSPF
S1947 TDDSRRCSQVKLGSA
S1953 CSQVKLGSAADFLLD
K1986 RDEPCLLKRLPNNHI
R2041 RRAKVYGRGLSEGRT
S2044 KVYGRGLSEGRTFEM
S2067 DAGYGGISLAVEGPS
S2114 ADEHVPGSPFTVKIS
T2117 HVPGSPFTVKISGEG
K2119 PGSPFTVKISGEGRV
S2129 GEGRVKESITRTSRA
T2131 GRVKESITRTSRAPS
T2133 VKESITRTSRAPSVA
S2138 TRTSRAPSVATVGSI
S2166 DMSAHVTSPSGRVTE
K2201 GVHTVSVKYRGQHVT
T2270 GPSKAEITFDDHKNG
Y2291 IAQEPGNYEVSIKFN
Y2307 EHIPESPYLVPVIAP
T2322 SDDARRLTVMSLQES
S2329 TVMSLQESGLKVNQP
S2356 KIDAKVHSPSGAVEE
Y2374 SELEPDKYAVRFIPH
S2400 NGSHVVGSPFKVRVG
S2434 GGTTGIQSEFFINTT
T2441 SEFFINTTRAGPGTL
S2456 SVTIEGPSKVKMDCQ
Y2469 CQETPEGYKVMYTPM
S2484 APGNYLISVKYGGPN
Y2487 NYLISVKYGGPNHIV
S2496 GPNHIVGSPFKAKVT
T2503 SPFKAKVTGQRLVSP
S2509 VTGQRLVSPGSANET
S2512 QRLVSPGSANETSSI
S2518 GSANETSSILVESVT
T2531 VTRSSTETCYSAIPK
Y2533 RSSTETCYSAIPKAS
S2534 SSTETCYSAIPKASS
S2541 SAIPKASSDASKVTS
S2548 SDASKVTSKGAGLSK
K2555 SKGAGLSKAFVGQKS
K2555 SKGAGLSKAFVGQKS
T2584 LIGVHGPTTPCEEVS
T2585 IGVHGPTTPCEEVSM
N2597 VSMKHVGNQQYNVTY
K2607 YNVTYVVKERGDYVL
  mouse

 
K15-a LAEDAPWkkIQQNTF
K16-u AEDAPWkkIQQNTFT
K60 LLEVLSQKRMHHKYH
T267-p YGRGIEPtGNMVKQP
N346 SKSPFEVNVDKAQGD
K492 GELGVTVKGPkGLEE
K492-u GELGVTVkGPkGLEE
K495-u GVTVkGPkGLEELVk
K502-u kGLEELVkQKGFLDG
Y511-p KGFLDGVySFEYYPS
S518 ySFEYYPStPGKYSV
T519-p SFEYYPStPGKYSVA
T528 GKYSVAVTWGGHHIP
S537 GGHHIPKSPFEVQVG
Y596 PSQAKIEYDDQNDGS
S630 DDEDIKDSPYMAFIH
T640 MAFIHPATGDYNPDL
S658-p YGPGLEKsGCTINNP
S677 VDPKDAGSAPLKILA
K681 DAGSAPLKILAQDGE
K681 DAGSAPLKILAQDGE
K697-u QPIDIQMkSRMDGTy
Y704-p kSRMDGTyACSYtPL
Y708 DGTyACSYtPLKAIK
T709-p GTyACSYtPLKAIKH
S730 GGVNIPHSPYRVNIG
Y732 VNIPHSPYRVNIGQG
S740 RVNIGQGSHPQKVKV
S833-p ASQEIPAsPFRVKVD
S886 PLNVQFSSPLPGEAV
Y902 DLDIIDNYDySHTVK
Y904-p DIIDNYDySHTVKYT
S932 GGDPIPKSPFTVGVA
A965 VGKDQEFAIDTNGAG
T968 DQEFAIDTNGAGGQG
T980 GQGKLDVTILsPSRK
S983-p KLDVTILsPSRKVVP
Y1020 LFAVDVTYDGHPVPG
D1021 FAVDVTYDGHPVPGS
S1028 DGHPVPGSPYTVEAS
K1147 GPGLEHGKVGEPGIL
S1181 SGAKAEVSIQNNKDG
T1198 AVTYVPLTAGMYTLT
T1203 PLTAGMYTLTMKYGG
K1241-u FGPGIEGkDVFREAT
T1259 TVDSRPLTQVGGDHI
S1316-p DDVPIPNsPFKVAVT
K1339-u HAQGPGLkEAFTNKS
Y1395-p IPFAPGDyDVNITYG
S1422 SKDVVDPSKVKIAGP
S1433 IAGPGLSSCVRACIP
S1448 QSFTVDSSKAGLAPL
D1476 VNVVDNGDGTHTVTY
S1505-p ADEEIPRsPFkVKVL
K1508-u EIPRsPFkVKVLPTY
Y1530 SGPGLSAYGVPASLP
S1535 SAYGVPASLPVEFAI
T1557-p GLLAVQItDQEGKPQ
K1572-u RATVHDNkDGTYAVT
Y1576 HDNkDGTYAVTYIPD
T1579 kDGTYAVTYIPDKTG
S1602 GGDNIPLSPYRIRAT
T1609 SPYRIRATQTGDASK
K1641-u VGFVVDAkTAGKGKV
Y1684 TAAKPGTYVIYVRFG
Y1687 KPGTYVIYVRFGGVD
Y1733 PWVTEEAYVPVSDMN
K1757 VIPFAVRKGEITGTV
T1773 MPSGKKATPEIVDNk
K1780-u TPEIVDNkDGTVTVR
T1783 IVDNkDGTVTVRYAP
T1785 DNkDGTVTVRYAPTE
T1791 VTVRYAPTEVGLHEM
K1897-u ILVKYNDkHIPGSPF
S1916-p TDDNRRCsQVKLGSA
S1922 CsQVKLGSAADFLLD
K1955 RDEPCLLKRLPNNHI
Q2010 RRAKVYGQGLSEGRT
S2013 KVYGQGLSEGRTFEM
S2036 DAGYGGISLAVEGPS
S2083-p ADEHVPGsPFTVkIS
T2086 HVPGsPFTVkISGEG
K2088-u PGsPFTVkISGEGRV
S2098-p GEGRVREsItRTSRA
T2100-p GRVREsItRTSRAPA
T2102 VREsItRTSRAPAVA
A2107 tRTSRAPAVATVGSI
S2135 DMSAHVTSPSGHVTE
K2170 GVHTVSVKYRGQHVT
T2239 GPSKAEITFDDHKNG
Y2260 IAQEPGNYEVSIKFN
Y2276 EHIPDSPYLVPVIAP
T2291 SDDARCLTVLSLQES
S2298 TVLSLQESGLKVNQP
S2325 KIDAKVHSPSGAVEE
Y2343 SELEPDKYAVRFIPH
S2369-p NGSHVVGsPFKVRVG
S2403 TGTTGIQSEFFINTT
T2410 SEFFINTTQAGPGTL
S2425 SVTIEGPSKVKMDCQ
Y2438 CQEIPEGYKVMYTPM
G2453 APGNYLIGVKyGGPN
Y2456-p NYLIGVKyGGPNHIS
S2465-p GPNHISRsPFKAKVT
T2472 sPFKAKVTGQRLVsP
S2478-p VTGQRLVsPGsANET
S2481-p QRLVsPGsANETSSI
S2487 GsANETSSILVESVT
T2500 VTRSSTETCysAIPK
Y2502-p RSSTETCysAIPKSS
S2503-p SSTETCysAIPKSSS
S2510 sAIPKSSSDASKVTS
S2517 SDASKVTSKGAGLSk
K2524 SKGAGLSKAFVGQKS
K2524-u SKGAGLSkAFVGQKS
T2553-p LIGVHGPttPCEEVS
T2554-p IGVHGPttPCEEVSM
K2566-u VSMKHVGkQQYNVTY
K2576 YNVTYVVKERGDYVL
  rat

 
K15 LAEDAPWKKIQQNTF
K16 AEDAPWKKIQQNTFT
K60 LLEVLSQKRMHHKYH
T267 YGRGIESTGNMVKQP
N346 SKSPFEVNVDKAQGD
K492 GELAVTVKGPKGLEE
K492 GELAVTVKGPKGLEE
K495 AVTVKGPKGLEELVK
K502 KGLEELVKQKGFLDG
Y511 KGFLDGVYSFEYYPS
S518 YSFEYYPSTPGKYSI
T519 SFEYYPSTPGKYSIA
T528 GKYSIAVTWGGHHIP
S537 GGHHIPKSPFEVQVG
Y596 PSQAKIEYDDQNDGS
S630 DDEDIKDSPYMAFIH
T640 MAFIHPATGDYNPDL
T658 YGPGLEKTGCTINNP
N677 VDPKDAGNAPLKILA
K681 DAGNAPLKILAQDGE
K681 DAGNAPLKILAQDGE
K697 QPIDIQMKSRMDGTY
Y704 KSRMDGTYVCSYTPV
Y708 DGTYVCSYTPVKAIK
T709 GTYVCSYTPVKAIKH
S730 GGVNIPHSPYRVNIG
Y732 VNIPHSPYRVNIGQG
S740 RVNIGQGSHPQKVKV
S833 ASEEIPASPFRVKVD
S886 PLNVQFSSPVPGEAV
Y902 DLDIIDNYDYSHTVK
Y904 DIIDNYDYSHTVKYT
S932 GGDPIPKSPFTVGVA
A965 VGKDQEFAIDTNGAG
T968 DQEFAIDTNGAGGQG
T980 GQGKLDVTILSPSRK
S983 KLDVTILSPSRKVVP
Y1020 LFAVDVTYDGHPVPG
D1021 FAVDVTYDGHPVPGS
S1028 DGHPVPGSPYTVEAS
K1147 GPGLEHGKVGEPGIL
S1181 SGAKAEVSIQNNKDG
T1198 AVTYVPLTAGMYTLT
T1203 PLTAGMYTLTMKYGG
K1241 FGPGIEGKDVFREAT
T1259 TVDARPLTQVGGDHI
S1316 DDAPIPNSPFKVAVN
K1339 HAQGPGLKEAFTNKP
Y1395 IPFAPGDYDVNITYG
S1422 SKDVVDPSKVKIAGP
S1433 IAGPGLSSCVRACIP
S1448 QSFTVDTSKAGLAPL
D1476 VDVVDNGDGTHTVTY
S1505 ADEEIPRSPFKVKVL
K1508 EIPRSPFKVKVLPTY
Y1530 SGPGLSAYGVPASLP
S1535 SAYGVPASLPVEFAI
T1557 GLLAVQITDQEGKPQ
K1572 RATVHDNKDGTYAVT
Y1576 HDNKDGTYAVTYIPD
T1579 KDGTYAVTYIPDKTG
S1602 GGDNIPLSPYRIRAT
T1609 SPYRIRATQTGDASK
K1641 VGFVVDAKTAGKGKV
Y1684 TAAKPGTYVIYVRFG
Y1687 KPGTYVIYVRFGGVD
Y1709 VMVTEEAYVPVSDMN
K1733 VIPFAVRKGEITGQV
T1749 MPSGKKATPEIVDNK
K1756 TPEIVDNKDGTVTVR
T1759 IVDNKDGTVTVRYAP
T1761 DNKDGTVTVRYAPTE
T1767 VTVRYAPTEVGLHEM
K1873 ILVKYNDKHIPGSPF
S1892 TDDSRRCSQVKLGSA
S1898 CSQVKLGSAADFLLD
K1931 RDEPCLLKRLPNNHI
R1986 RRAKVYGRGLSEGRT
S1989 KVYGRGLSEGRTFEM
S2012 DAGYGGISLAVEGPS
S2059 ADEHVPGSPFTVKIS
T2062 HVPGSPFTVKISGEG
K2064 PGSPFTVKISGEGRV
S2074 GEGRVKESITRTSRA
T2076 GRVKESITRTSRAPs
T2078 VKESITRTSRAPsVA
S2083-p TRTSRAPsVATVGSI
S2111 DMSAHVTSPSGHVTE
K2146 GVHTVSVKYRGQHVT
T2215 GPSKAEITFDDHKNG
Y2236 IAQEPGNYEVSIKFN
Y2252 EHIPDSPYLVPVIAP
T2267 SDDARCLTVLSLQES
S2274 TVLSLQESGLKVNQP
S2301 KIDAKVHSPSGAVEE
Y2319 SELEPDKYAVRFIPH
S2345 NGSHVVGSPFKVRVG
S2379 AGTTGIQSEFFINTT
T2386 SEFFINTTQAGPGTL
S2401 SVTIEGPSKVKMDCQ
Y2414 CQEIPEGYKVMYTPM
S2429 APGNYLISVKYGGPN
Y2432 NYLISVKYGGPNHIS
S2441 GPNHISRSPFKAKVT
T2448 SPFKAKVTGQRLVTP
T2454 VTGQRLVTPGSANET
S2457 QRLVTPGSANETSSI
S2463 GSANETSSILVESVT
T2476 VTRSSTETCYSAIPK
Y2478 RSSTETCYSAIPKSS
S2479 SSTETCYSAIPKSSS
S2486 SAIPKSSSDASKVTS
S2493 SDASKVTSKGAGLSK
K2500 SKGAGLSKAFVGQKS
K2500 SKGAGLSKAFVGQKS
T2529 LIGVHGPTTPCEEVS
T2530 IGVHGPTTPCEEVSM
K2542 VSMKHVGKQQYNVTY
K2552 YNVTYVVKEKGDYVL
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