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FLNB (human)

Overview FLNB a ubiquitous cytoskeletal protein that links actin filaments to membrane glycoproteins. Six alternatively spliced isoforms have been described. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoforms 1 and 2 are expressed in placenta, bone marrow, brain, umbilical vein endothelial cells, retina and skeletal muscle. Isoform 1 is predominantly expressed in prostate, uterus, liver, thyroid, stomach, lymph node, small intestine, spleen, skeletal muscle, kidney, placenta, pancreas, heart, lung, platelets, endothelial cells, megakaryocytic and erythroleukemic cell lines. Isoform 2 is predominantly expressed in spinal cord and platelets. Also expressed in thyroid adenoma, neurofibrillary tangles (NFT), senile plaques in the hippocampus and cerebral cortex in Alzheimer's disease. Isoform 3 and isoform 6 are expressed predominantly in lung, heart, skeletal muscle, testis, spleen, thymus and leukocytes. Isoform 4 and isoform 5 are expressed in heart. Note: This description may include information from UniProtKB. Protein type: Actin binding protein; Motility/polarity/chemotaxis Cellular Component: focal adhesion; cytoplasm; stress fiber; integral to membrane; plasma membrane; cell cortex; Z disc; cytosol; actin cytoskeleton Molecular Function: identical protein binding; protein binding; actin binding Biological Process: skeletal muscle development; cytoskeletal anchoring; cytokine and chemokine mediated signaling pathway; signal transduction; cell differentiation; actin cytoskeleton organization and biogenesis Reference #:  O75369 (UniProtKB) Alt. Names/Synonyms: ABP-278; ABP-280; ABP-280 homolog; actin binding protein 278; Actin-binding-like protein; AOI; Beta-filamin; DKFZp686A1668; DKFZp686O033; Fh1; filamin 1 (actin-binding protein-280)-like; filamin B, beta; Filamin homolog 1; Filamin-3; Filamin-B; FLN-B; FLN1L; FLN3; FLNB; LRS1; SCT; TABP; TAP; Thyroid autoantigen; Truncated ABP; Truncated actin-binding protein Gene Symbols: FLNB Molecular weight: 278,164 Da Basal Isoelectric point: 5.47  Predict pI for various phosphorylation states CST Pathways:  Regulation of Actin Dynamics Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below FLNB 2DI8 - A=1997-2096 (human) 2DI9 - A=1017-1140 (human) 2DIA - A=1016-1035 (human) 2DIB - A=1215-1335 (human) 2DIC - A=1325-1422 (human) 2DJ4 - A=1418-1518 (human) 2DLG - A=2104-2192 (human) 2DMB - A=1611-1721 (human) 2DMC - A=1899-2001 (human) 2E9I - A=2093-2192 (human) 2E9J - A=1504-1615 (human) 2EE6 - A=2186-2287 (human) 2EE9 - A=1736-1823 (human) 2EEA - A=1804-1915 (human) 2EEB - A=2284-2382 (human) 2EEC - A=2369-2488 (human) 2EED - A=2509-2602 (human) 2WA5 - A=2-242 (human) 2WA6 - A=2-242 (human) 2WA7 - A=2-242 (human) 3FER - A/D/C/B=1-252 (human) 4B7L - A/B=1-347 (human)

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB 2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L  |  Phospho3D  |  DISEASE 108720 108721 112310 150250 272460 603381  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	3		K15-a	LAEDAPWkkIQQNTF
0	4		K16-u	AEDAPWkkIQQNTFT
0	3		K60-u	LLEVLSQkRMYRKYH
0	1		K93	FLDRESIKLVSIDSK
0	1		K142-a	DAKKQTPkQRLLGWI
0	1		K169-a	NQNWQDGkALGALVD
0	2		T267-p	YGRGIEPtGNMVKQP
0	1		S339-p	LFAGQHIsKSPFEVs
0	1		S346-p	sKSPFEVsVDKAQGD
0	1		Y376-p	NIANKPTyFDIYTAG
0	1		Y414-p	EDKGNQVyRCVYKPM
0	1		Y418	NQVyRCVYKPMQPGP
0	1		S440-p	AGDTIPKsPFVVQVG
0	1		T472-p	KGVRIREttDFKVDT
0	1		T473-p	GVRIREttDFKVDTk
0	1		K480-a	tDFKVDTkAAGsGEL
0	1		S484-p	VDTkAAGsGELGVTM
0	2		K492-a	GELGVTMkGPkGLEE
0	1		K492	GELGVTMKGPkGLEE
0	3		K495-u	GVTMkGPkGLEELVk
0	1		K502-a	kGLEELVkQKDFLDG
0	2		K502-u	kGLEELVkQKDFLDG
0	2		Y511	KDFLDGVYAFEYYPs
0	6		S518-p	YAFEYYPstPGRYSI
0	24		T519-p	AFEYYPstPGRYSIA
0	1		T528-p	GRYSIAItWGGHHIP
0	1		S537-p	GGHHIPKsPFEVQVG
0	1		S567-p	HGGIVGRsADFVVES
0	2		Y596-p	PSQAKIEyNDQNDGS
0	1		S630-p	DDEDIKDsPyMAFIH
0	1		Y632-p	EDIKDsPyMAFIHPA
0	1		T640-p	MAFIHPAtGGYNPDL
0	2		S658-p	YGPGLEKsGCIVNNL
0	4		K677-a	VDPKDAGkAPLkIFA
0	16		K681-a	DAGkAPLkIFAQDGE
0	1		K681-u	DAGkAPLkIFAQDGE
0	1		K697	QRIDIQMKNRMDGTy
0	127		Y704-p	KNRMDGTyACsytPV
0	1		S707-p	MDGTyACsytPVKAI
0	3		Y708-p	DGTyACsytPVKAIK
0	2		T709-p	GTyACsytPVKAIKH
0	2		S730-p	GGVNIPHsPyRVNIG
0	1		Y732-p	VNIPHsPyRVNIGQG
0	2		S740-p	RVNIGQGsHPQKVKV
0	4		S833-p	ASQEIPAsPFRVKVD
0	1		T869-p	NGKPTHFtVYTKGAG
0	2		S886-p	PLNVQFNsPLPGDAV
0	1		Y902-p	DLDIIDNyDySHtVK
0	18		Y904-p	DIIDNyDySHtVKYT
0	1		T907-p	DNyDySHtVKYTPTQ
0	2		S932-p	GGDPIPKsPFTVGVA
0	1		T965-p	VGKDQEFtVDtRGAG
0	1		T968-p	DQEFtVDtRGAGGQG
0	2		T980-p	GQGKLDVtILsPsRK
0	10		S983-p	KLDVtILsPsRKVVP
0	1		S985-p	DVtILsPsRKVVPCL
0	1		Y1020-p	LYAVDVTydGHPVPG
0	1		D1021-ca	YAVDVTydGHPVPGs
0	2		S1028-p	dGHPVPGsPYTVEAS
1	0		K1147-u	GPGLEHGkVGEAGLL
0	1		S1181-p	SGTKAEVsIQNNKDG
0	1		T1189-p	IQNNKDGtYAVTYVP
0	1		T1198-p	AVTYVPLtAGMYtLT
0	1		T1203-p	PLtAGMYtLTMKYGG
0	1		K1241	FGPGIEGKDVFREAT
0	1		T1259-p	TVDSRPLtQVGGDHI
0	3		S1316-p	DDVPIPNsPFKVAVT
0	1		K1339	QAQGPGLKEAFTNKP
0	1		Y1395	IPFAPGDYDVNITYG
0	1		S1422-p	VKDVVDPsKVKIAGP
0	4		S1433-p	IAGPGLGsGVRARVL
0	1		S1448-p	QSFTVDSskAGLAPL
0	1		K1449-u	SFTVDSskAGLAPLE
0	1		D1476-ca	VNVVDNGdGTHTVTY
0	15		S1505-p	ADEEIPRsPFKVKVL
0	1		K1508	EIPRsPFKVKVLPTY
0	1		S1529-p	ASGPGLSsyGVPAsL
0	61		Y1530-p	SGPGLSsyGVPAsLP
0	1		S1535-p	SsyGVPAsLPVDFAI
0	1		T1557	GLLAVQITDQEGKPK
0	1		K1572	RAIVHDNKDGTyAVt
0	3		Y1576-p	HDNKDGTyAVtYIPD
0	1		T1579-p	KDGTyAVtYIPDKtG
0	1		T1585-p	VtYIPDKtGRYMIGV
0	1		S1602-p	GGDDIPLsPYRIRAt
0	8		T1609-p	sPYRIRAtQTGDASk
0	1		K1616-a	tQTGDASkCLATGPG
0	1		K1641-a	VGFVVDAkTAGKGKV
0	1		K1641	VGFVVDAKTAGKGKV
0	2		Y1684-p	TAAKPGTyVIyVRFG
0	10		Y1687-p	KPGTyVIyVRFGGVD
0	3		Y1733-p	PWVTEEAyVPVSDMN
0	1		K1757-u	VIPFAVRkGEITGEV
0	1		T1773-p	MPSGKTAtPEIVDNK
0	1		K1780	tPEIVDNKDGtVtVR
0	1		T1783-p	IVDNKDGtVtVRYAP
0	1		T1785-p	DNKDGtVtVRYAPtE
0	1		T1791-p	VtVRYAPtEVGLHEM
0	1		Y1833-p	AYGPGLVyGVANKTA
0	2		K1897-u	ILVKYNDkHIPGSPF
0	1		S1916-p	TDDSRRCsQVKLGsA
0	1		S1922-p	CsQVKLGsAADFLLD
0	1		S1937-p	ISETDLSsLTASIKA
0	1		K1955-u	RDEPCLLkRLPNNHI
0	1		S1997-p	VSIMVVQsEIGDARR
0	1		S2013-p	KVYGRGLsEGRTFEM
0	1		S2036-p	DAGYGGIsLAVEGPS
0	1		Y2061-p	DGTCKVSyFPTVPGV
0	4		S2083-p	ADEHVPGsPFtVKIS
0	1		T2086-p	HVPGsPFtVKISGEG
0	1		K2088	PGsPFtVKISGEGRV
0	1		S2098-p	GEGRVKEsITRtSRA
0	1		T2100	GRVKEsITRtSRAPs
0	2		T2102-p	VKEsITRtSRAPsVA
0	11		S2107-p	TRtSRAPsVATVGSI
0	1		S2135-p	DMSAHVTsPSGRVTE
0	1		K2170-a	GVHTVSVkYRGQHVT
0	1		T2239-p	GPSKAEItFDDHKNG
0	1		Y2260-p	IAQEPGNyEVSIKFN
0	1		Y2276-p	EHIPESPyLVPVIAP
0	2		T2291-p	SDDARRLtVMSLQEs
0	1		S2298-p	tVMSLQEsGLKVNQP
0	1		S2325-p	KIDAKVHsPsGAVEE
0	1		S2327-p	DAKVHsPsGAVEECH
0	1		S2336-p	AVEECHVsELEPDKy
0	29		Y2343-p	sELEPDKyAVRFIPH
0	4		S2369-p	NGSHVVGsPFKVRVG
0	1		S2403-p	GGTTGIQsEFFINTt
0	1		T2410-p	sEFFINTtRAGPGTL
0	1		S2425-p	SVTIEGPsKVKMDCQ
0	1		Y2438-p	CQETPEGyKVMYTPM
0	1		S2453-p	APGNYLIsVKYGGPN
0	1		Y2456	NYLIsVKYGGPNHIV
0	1		V2463	YGGPNHIVGsPFKAK
0	7		S2465-p	GPNHIVGsPFKAKVt
0	1		T2472-p	sPFKAKVtGQRLVsP
0	11		S2478-p	VtGQRLVsPGsANET
0	3		S2481-p	QRLVsPGsANETSsI
0	1		S2487-p	GsANETSsILVESVt
0	1		T2494-p	sILVESVtRSSTEtC
0	2		T2500-p	VtRSSTEtCysAIPK
0	835		Y2502-p	RSSTEtCysAIPKAS
0	3		S2503-p	SSTEtCysAIPKASs
0	1		S2510-p	sAIPKASsDASKVTs
0	1		S2517-p	sDASKVTsKGAGLSk
0	2		K2524-a	sKGAGLSkAFVGQKS
0	2		K2524-u	sKGAGLSkAFVGQKS
0	1		S2542-p	VDCSKAGsNMLLIGV
0	2		T2553-p	LIGVHGPttPCEEVS
0	7		T2554-p	IGVHGPttPCEEVSM
0	1		N2566	VSMKHVGNQQYNVTY
0	1		K2576-a	YNVTYVVkERGDYVL

	mouse
K15-a	LAEDAPWkkIQQNTF
K16-u	AEDAPWkkIQQNTFT
K60	LLEVLSQKRMHHKYH
K93-a	FLDHESIkLVSIDSK
K142	DAKKQTPKQRLLGWI
K169	NQNWQDGKALGALVD
T267-p	YGRGIEPtGNMVKQP
S339	LFAGQHISKSPFEVN
N346	SKSPFEVNVDKAQGD
Y376	NIANKPTYFDIYTAG
Y414	EDRGNQVYRCVYKPV
Y418	NQVYRCVYKPVQPGP
S440	AGDAIPKSPFGVQIG
T472	KGVRIRETADFKVDT
A473	GVRIRETADFKVDTK
K480	ADFKVDTKAAGSGEL
S484	VDTKAAGSGELGVTV
K492	GELGVTVKGPkGLEE
K492-u	GELGVTVkGPkGLEE
K495-u	GVTVkGPkGLEELVk
K502	kGLEELVKQKGFLDG
K502-u	kGLEELVkQKGFLDG
Y511-p	KGFLDGVySFEYYPS
S518	ySFEYYPStPGKYSV
T519-p	SFEYYPStPGKYSVA
T528	GKYSVAVTWGGHHIP
S537	GGHHIPKSPFEVQVG
S567	HGGIVGRSADFVVES
Y596	PSQAKIEYDDQNDGS
S630	DDEDIKDSPYMAFIH
Y632	EDIKDSPYMAFIHPA
T640	MAFIHPATGDYNPDL
S658-p	YGPGLEKsGCTINNP
S677	VDPKDAGSAPLKILA
K681	DAGSAPLKILAQDGE
K681	DAGSAPLKILAQDGE
K697-u	QPIDIQMkSRMDGTy
Y704-p	kSRMDGTyACSYtPL
S707	MDGTyACSYtPLKAI
Y708	DGTyACSYtPLKAIK
T709-p	GTyACSYtPLKAIKH
S730	GGVNIPHSPYRVNIG
Y732	VNIPHSPYRVNIGQG
S740	RVNIGQGSHPQKVKV
S833-p	ASQEIPAsPFRVKVD
T869	NGKPTHFTVHTKGAG
S886	PLNVQFSSPLPGEAV
Y902	DLDIIDNYDYSHTVK
Y904	DIIDNYDYSHTVKYT
T907	DNYDYSHTVKYTPTQ
S932	GGDPIPKSPFTVGVA
A965	VGKDQEFAIDTNGAG
T968	DQEFAIDTNGAGGQG
T980	GQGKLDVTILsPSRK
S983-p	KLDVTILsPSRKVVP
S985	DVTILsPSRKVVPCL
Y1020	LFAVDVTYDGHPVPG
D1021	FAVDVTYDGHPVPGS
S1028	DGHPVPGSPYTVEAS
K1147	GPGLEHGKVGEPGIL
S1181	SGAKAEVSIQNNKDG
T1189	IQNNKDGTYAVTYVP
T1198	AVTYVPLTAGMYTLT
T1203	PLTAGMYTLTMKYGG
K1241-u	FGPGIEGkDVFREAT
T1259	TVDSRPLTQVGGDHI
S1316	DDVPIPNSPFKVAVT
K1339-u	HAQGPGLkEAFTNKS
Y1395-p	IPFAPGDyDVNITYG
S1422	SKDVVDPSKVKIAGP
S1433	IAGPGLSSCVRACIP
S1448	QSFTVDSSKAGLAPL
K1449	SFTVDSSKAGLAPLE
D1476	VNVVDNGDGTHTVTY
S1505-p	ADEEIPRsPFkVKVL
K1508-u	EIPRsPFkVKVLPTY
A1529	ASGPGLSAYGVPASL
Y1530	SGPGLSAYGVPASLP
S1535	SAYGVPASLPVEFAI
T1557-p	GLLAVQItDQEGKPQ
K1572-u	RATVHDNkDGTYAVT
Y1576	HDNkDGTYAVTYIPD
T1579	kDGTYAVTYIPDKTG
T1585	VTYIPDKTGRYMIGV
S1602	GGDNIPLSPYRIRAT
T1609	SPYRIRATQTGDASK
K1616	TQTGDASKCLATGPG
K1641	VGFVVDAKTAGKGKV
K1641-u	VGFVVDAkTAGKGKV
Y1684	TAAKPGTYVIYVRFG
Y1687	KPGTYVIYVRFGGVD
Y1733	PWVTEEAYVPVSDMN
K1757	VIPFAVRKGEITGTV
T1773	MPSGKKATPEIVDNk
K1780-u	TPEIVDNkDGTVTVR
T1783	IVDNkDGTVTVRYAP
T1785	DNkDGTVTVRYAPTE
T1791	VTVRYAPTEVGLHEM
Y1833	AYGPGLVYGVANKTA
K1897-u	ILVKYNDkHIPGSPF
S1916	TDDNRRCSQVKLGSA
S1922	CSQVKLGSAADFLLD
T1937	ISETDLSTLTASIKA
K1955	RDEPCLLKRLPNNHI
S1997	VSIMVVQSEIGDARR
S2013	KVYGQGLSEGRTFEM
S2036	DAGYGGISLAVEGPS
Y2061	DGTCKVSYFPTVPGV
S2083-p	ADEHVPGsPFTVkIS
T2086	HVPGsPFTVkISGEG
K2088-u	PGsPFTVkISGEGRV
S2098-p	GEGRVREsItRTSRA
T2100-p	GRVREsItRTSRAPA
T2102	VREsItRTSRAPAVA
A2107	tRTSRAPAVATVGSI
S2135	DMSAHVTSPSGHVTE
K2170	GVHTVSVKYRGQHVT
T2239	GPSKAEITFDDHKNG
Y2260	IAQEPGNYEVSIKFN
Y2276	EHIPDSPYLVPVIAP
T2291	SDDARCLTVLSLQES
S2298	TVLSLQESGLKVNQP
S2325	KIDAKVHSPSGAVEE
S2327	DAKVHSPSGAVEECH
S2336	AVEECHVSELEPDKY
Y2343	SELEPDKYAVRFIPH
S2369-p	NGSHVVGsPFKVRVG
S2403	TGTTGIQSEFFINTT
T2410	SEFFINTTQAGPGTL
S2425	SVTIEGPSKVKMDCQ
Y2438	CQEIPEGYKVMYTPM
G2453	APGNYLIGVKyGGPN
Y2456-p	NYLIGVKyGGPNHIs
S2463-p	yGGPNHIsRsPFKAK
S2465-p	GPNHIsRsPFKAKVT
T2472	sPFKAKVTGQRLVsP
S2478-p	VTGQRLVsPGsANET
S2481-p	QRLVsPGsANETSSI
S2487	GsANETSSILVESVT
T2494	SILVESVTRSSTETC
T2500	VTRSSTETCysAIPK
Y2502-p	RSSTETCysAIPKSS
S2503-p	SSTETCysAIPKSSS
S2510	sAIPKSSSDASKVTS
S2517	SDASKVTSKGAGLSk
K2524	SKGAGLSKAFVGQKS
K2524-u	SKGAGLSkAFVGQKS
S2542	VDCSKAGSNMLLIGV
T2553-p	LIGVHGPttPCEEVS
T2554-p	IGVHGPttPCEEVSM
K2566-u	VSMKHVGkQQYNVTY
K2576	YNVTYVVKERGDYVL

	rat
K15	LAEDAPWKKIQQNTF
K16	AEDAPWKKIQQNTFT
K60	LLEVLSQKRMHHKYH
K93	FLDHESIKLVSIDSK
K142	DAKKQTPKQRLLGWI
K169	NQNWQDGKALGALVD
T267	YGRGIESTGNMVKQP
S339	LFAGQHISKSPFEVN
N346	SKSPFEVNVDKAQGD
Y376	NIANKPTYFDIYTAG
Y414-p	EDRGNQVyRCVyKPL
Y418-p	NQVyRCVyKPLQPGP
S440	AGDAIPKSPFGVQIG
T472	KGVRIRETADFKVDT
A473	GVRIRETADFKVDTK
K480	ADFKVDTKAAGSGEL
S484	VDTKAAGSGELAVTV
K492	GELAVTVKGPKGLEE
K492	GELAVTVKGPKGLEE
K495	AVTVKGPKGLEELVK
K502	KGLEELVKQKGFLDG
K502	KGLEELVKQKGFLDG
Y511	KGFLDGVYSFEYYPS
S518	YSFEYYPSTPGKYSI
T519	SFEYYPSTPGKYSIA
T528	GKYSIAVTWGGHHIP
S537	GGHHIPKSPFEVQVG
S567	HGGIVGRSADFVVES
Y596	PSQAKIEYDDQNDGS
S630	DDEDIKDSPYMAFIH
Y632	EDIKDSPYMAFIHPA
T640	MAFIHPATGDYNPDL
T658	YGPGLEKTGCTINNP
N677	VDPKDAGNAPLKILA
K681	DAGNAPLKILAQDGE
K681	DAGNAPLKILAQDGE
K697	QPIDIQMKSRMDGTY
Y704	KSRMDGTYVCSYTPV
S707	MDGTYVCSYTPVKAI
Y708	DGTYVCSYTPVKAIK
T709	GTYVCSYTPVKAIKH
S730	GGVNIPHSPYRVNIG
Y732	VNIPHSPYRVNIGQG
S740	RVNIGQGSHPQKVKV
S833	ASEEIPASPFRVKVD
T869	NGKPTHFTVHTKGAG
S886	PLNVQFSSPVPGEAV
Y902	DLDIIDNYDYSHTVK
Y904	DIIDNYDYSHTVKYT
T907	DNYDYSHTVKYTPTQ
S932	GGDPIPKSPFTVGVA
A965	VGKDQEFAIDTNGAG
T968	DQEFAIDTNGAGGQG
T980	GQGKLDVTILSPSRK
S983	KLDVTILSPSRKVVP
S985	DVTILSPSRKVVPCL
Y1020	LFAVDVTYDGHPVPG
D1021	FAVDVTYDGHPVPGS
S1028	DGHPVPGSPYTVEAS
K1147	GPGLEHGKVGEPGIL
S1181	SGAKAEVSIQNNKDG
S1189	IQNNKDGSYAVTYVP
T1198	AVTYVPLTAGMYTLT
T1203	PLTAGMYTLTMKYGG
K1241	FGPGIEGKDVFREAT
T1259	TVDARPLTQVGGDHI
S1316	DDAPIPNSPFKVAVN
K1339	HAQGPGLKEAFTNKP
Y1395	IPFAPGDYDVNITYG
S1422	SKDVVDPSKVKIAGP
S1433	IAGPGLSSCVRACIP
S1448	QSFTVDTSKAGLAPL
K1449	SFTVDTSKAGLAPLE
D1476	VDVVDNGDGTHTVTY
S1505	ADEEIPRSPFKVKVL
K1508	EIPRSPFKVKVLPTY
A1529	ASGPGLSAYGVPASL
Y1530	SGPGLSAYGVPASLP
S1535	SAYGVPASLPVEFAI
T1557	GLLAVQITDQEGKPQ
K1572	RATVHDNKDGTYAVT
Y1576	HDNKDGTYAVTYIPD
T1579	KDGTYAVTYIPDKTG
T1585	VTYIPDKTGRYMIGV
S1602	GGDNIPLSPYRIRAT
T1609	SPYRIRATQTGDASK
K1616	TQTGDASKCLATGPG
K1641	VGFVVDAKTAGKGKV
K1641	VGFVVDAKTAGKGKV
Y1684	TAAKPGTYVIYVRFG
Y1687	KPGTYVIYVRFGGVD
Y1733	PWVTEEAYVPVSDMN
K1757	VIPFAVRKGEITGQV
T1773	MPSGKKATPEIVDNK
K1780	TPEIVDNKDGTVTVR
T1783	IVDNKDGTVTVRYAP
T1785	DNKDGTVTVRYAPTE
T1791	VTVRYAPTEVGLHEM
Y1833	AYGPGLVYGVANKTA
K1897	ILVKYNDKHIPGSPF
S1916	TDDSRRCSQVKLGSA
S1922	CSQVKLGSAADFLLD
T1937	ISETDLSTLTASIKA
K1955	RDEPCLLKRLPNNHI
S1997	VSIMVVQSEIGDARR
S2013	KVYGRGLSEGRTFEM
S2036	DAGYGGISLAVEGPS
Y2061	DGTCKVSYFPTVPGV
S2083	ADEHVPGSPFTVKIS
T2086	HVPGSPFTVKISGEG
K2088	PGSPFTVKISGEGRV
S2098	GEGRVKESITRTSRA
T2100	GRVKESITRTSRAPs
T2102	VKESITRTSRAPsVA
S2107-p	TRTSRAPsVATVGSI
S2135	DMSAHVTSPSGHVTE
K2170	GVHTVSVKYRGQHVT
T2239	GPSKAEITFDDHKNG
Y2260	IAQEPGNYEVSIKFN
Y2276	EHIPDSPYLVPVIAP
T2291	SDDARCLTVLSLQES
S2298	TVLSLQESGLKVNQP
S2325	KIDAKVHSPSGAVEE
S2327	DAKVHSPSGAVEECH
S2336	AVEECHVSELEPDKY
Y2343	SELEPDKYAVRFIPH
S2369	NGSHVVGSPFKVRVG
S2403	AGTTGIQSEFFINTT
T2410	SEFFINTTQAGPGTL
S2425	SVTIEGPSKVKMDCQ
Y2438	CQEIPEGYKVMYTPM
S2453	APGNYLISVKYGGPN
Y2456	NYLISVKYGGPNHIS
S2463	YGGPNHISRSPFKAK
S2465	GPNHISRSPFKAKVT
T2472	SPFKAKVTGQRLVTP
T2478	VTGQRLVTPGSANET
S2481	QRLVTPGSANETSSI
S2487	GSANETSSILVESVT
T2494	SILVESVTRSSTETC
T2500	VTRSSTETCYSAIPK
Y2502	RSSTETCYSAIPKSS
S2503	SSTETCYSAIPKSSS
S2510	SAIPKSSSDASKVTS
S2517	SDASKVTSKGAGLSK
K2524	SKGAGLSKAFVGQKS
K2524	SKGAGLSKAFVGQKS
S2542	VDCSKAGSNMLLIGV
T2553	LIGVHGPTTPCEEVS
T2554	IGVHGPTTPCEEVSM
K2566	VSMKHVGKQQYNVTY
K2576	YNVTYVVKEKGDYVL

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