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Protein Page:
ENO1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ENO1 an abundant cytoplasmic enzyme with 2-phospho-D-glycerate hydro-lyase activity. A target of excess protein nitration in Alzheimer disease (AD) brain. Tau-crystallin, a structural lens protein, is produced from an alternative translation start in the enolase gene. Note: This description may include information from UniProtKB.
Protein type: Lyase; EC 4.2.1.11; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Transcription, coactivator/corepressor
Cellular Component: extracellular space; phosphopyruvate hydratase complex; membrane; cytoplasm; plasma membrane; M band; nucleus; cytosol
Molecular Function: protein binding; DNA binding; magnesium ion binding; phosphopyruvate hydratase activity; transcription factor activity; transcription corepressor activity
Biological Process: glycolysis; transcription, DNA-dependent; response to virus; carbohydrate metabolic process; glucose metabolic process; negative regulation of cell growth; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; gluconeogenesis
Reference #:  P06733 (UniProtKB)
Alt. Names/Synonyms: 2-phospho-D-glycerate hydro-lyase; alpha enolase like 1; Alpha-enolase; C-myc promoter-binding protein; ENO1; ENO1L1; ENOA; Enolase 1; enolase 1, (alpha); MBP-1; MBPB1; MPB-1; MPB1; MYC promoter-binding protein 1; NNE; Non-neural enolase; Phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin
Gene Symbols: ENO1
Molecular weight: 47,169 Da
Basal Isoelectric point: 7.01  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ENO1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 3 K5-ac ___MSILkIHAREIF
0 1 K5-ub ___MSILkIHAREIF
0 1 S14-p HAREIFDsRGNPtVE
0 1 T19-p FDsRGNPtVEVDLFt
0 80 F25 PtVEVDLFtskGLFR
0 2 T26-p tVEVDLFtskGLFRA
0 3 S27-p VEVDLFtskGLFRAA
0 2 K28-ac EVDLFtskGLFRAAV
0 24 K28-ub EVDLFtskGLFRAAV
0 5 S37-p LFRAAVPsGAstGIy
0 15 S40-p AAVPsGAstGIyEAL
0 69 T41-p AVPsGAstGIyEALE
2 1927 Y44-p sGAstGIyEALELRD
0 1 K54-ac LELRDNDktRyMGkG
0 2 K54-ub LELRDNDktRyMGkG
0 2 T55-p ELRDNDktRyMGkGV
0 1 Y57-p RDNDktRyMGkGVSk
0 4 K60-ac DktRyMGkGVSkAVE
0 22 K60-ub DktRyMGkGVSkAVE
0 2 K64-ac yMGkGVSkAVEHINk
0 87 K64-ub yMGkGVSkAVEHINk
0 6 K71-ac kAVEHINktIAPALV
0 14 K71-ub kAVEHINktIAPALV
0 1 K71-sc kAVEHINktIAPALV
0 1 T72-p AVEHINktIAPALVs
0 4 S79-p tIAPALVskkLNVTE
0 30 K80-ac IAPALVskkLNVTEQ
0 25 K80-ub IAPALVskkLNVTEQ
0 1 K80-sc IAPALVskkLNVTEQ
0 2 K81-ac APALVskkLNVTEQE
0 7 K81-ub APALVskkLNVTEQE
0 5 K89-ac LNVTEQEkIDkLMIE
0 36 K89-ub LNVTEQEkIDkLMIE
0 4 K92-ac TEQEkIDkLMIEMDG
0 5 K92-ub TEQEkIDkLMIEMDG
0 1 K92 TEQEkIDKLMIEMDG
0 2 T100-p LMIEMDGtENkSkFG
0 1 K103-ac EMDGtENkSkFGANA
0 2 K103-ub EMDGtENkSkFGANA
0 1 K105-ac DGtENkSkFGANAIL
0 1 K105-ub DGtENkSkFGANAIL
0 45 K120-ub GVSLAVCkAGAVEkG
0 5 K126-ac CkAGAVEkGVPLyRH
0 11 K126-ub CkAGAVEkGVPLyRH
0 1 K126-sc CkAGAVEkGVPLyRH
0 7 Y131-p VEkGVPLyRHIADLA
0 1 K162 GGSHAGNKLAMQEFM
0 173 Y189-p MRIGAEVyHNLkNVI
0 9 K193-ac AEVyHNLkNVIkEkY
0 32 K193-ub AEVyHNLkNVIkEkY
0 1 K193-sc AEVyHNLkNVIkEkY
0 12 K197-ac HNLkNVIkEkYGkDA
0 44 K197-ub HNLkNVIkEkYGkDA
0 9 K199-ac LkNVIkEkYGkDAtN
0 13 K202-ac VIkEkYGkDAtNVGD
0 59 K202-ub VIkEkYGkDAtNVGD
0 1 K202-sc VIkEkYGkDAtNVGD
0 1 T205-p EkYGkDAtNVGDEGG
0 5 K221-ac APNILENkEGLELLk
0 27 K221-ub APNILENkEGLELLk
0 1 K221-sc APNILENkEGLELLk
0 7 K228-ac kEGLELLkTAIGkAG
0 10 K228-ub kEGLELLkTAIGkAG
0 2 K233-ac LLkTAIGkAGytDkV
0 5 K233-ub LLkTAIGkAGytDkV
0 2 Y236-p TAIGkAGytDkVVIG
0 2 T237-p AIGkAGytDkVVIGM
0 1 K239-ac GkAGytDkVVIGMDV
0 8 S254-p AASEFFRsGkyDLDF
0 19 K256-ac SEFFRsGkyDLDFks
0 33 K256-ub SEFFRsGkyDLDFks
0 1 K256-sc SEFFRsGkyDLDFks
0 3 Y257-p EFFRsGkyDLDFksP
0 1 K262-ac GkyDLDFksPDDPsR
0 2 K262-ub GkyDLDFksPDDPsR
0 1 K262-sc GkyDLDFksPDDPsR
0 39 S263-p kyDLDFksPDDPsRy
0 2 S268-p FksPDDPsRyIsPDQ
0 3 Y270-p sPDDPsRyIsPDQLA
0 10 S272-p DDPsRyIsPDQLADL
0 5 Y280-p PDQLADLyksFIkDy
0 10 K281-ac DQLADLyksFIkDyP
0 4 K281-ub DQLADLyksFIkDyP
0 1 K281-sc DQLADLyksFIkDyP
0 10 S282-p QLADLyksFIkDyPV
0 3 K285-ac DLyksFIkDyPVVsI
0 21 K285-ub DLyksFIkDyPVVsI
0 1 K285-sc DLyksFIkDyPVVsI
0 187 Y287-p yksFIkDyPVVsIED
0 4 S291-p IkDyPVVsIEDPFDQ
0 1 K306-ac DDWGAWQkFTASAGI
0 1 S310 AWQkFTASAGIQVVG
0 37 K326-ac DLTVTNPkRIAkAVN
0 11 K326-ub DLTVTNPkRIAkAVN
0 1 K330-ac TNPkRIAkAVNEksC
0 9 K330-ub TNPkRIAkAVNEksC
0 1 K330-sc TNPkRIAkAVNEksC
0 1 N333 kRIAkAVNEksCNCL
0 12 K335-ac IAkAVNEksCNCLLL
0 10 K335-ub IAkAVNEksCNCLLL
0 1 K335-sc IAkAVNEksCNCLLL
0 2 S336-p AkAVNEksCNCLLLk
0 63 K343-ac sCNCLLLkVNQIGSV
0 93 K343-ub sCNCLLLkVNQIGSV
0 1 S349 LkVNQIGSVTESLQA
0 2 K358-ac TESLQACkLAQANGW
0 1 K358-sc TESLQACkLAQANGW
0 1 A362 QACkLAQANGWGVMV
0 1 S370-p NGWGVMVsHRSGETE
0 3 K394-ub GLCTGQIkTGAPCRS
0 16 K406-ac CRSERLAkYNQLLRI
0 3 K406-ub CRSERLAkYNQLLRI
0 1 K406-sc CRSERLAkYNQLLRI
1 13 S419-p RIEEELGskAkFAGR
0 2 K420-ac IEEELGskAkFAGRN
0 38 K420-ub IEEELGskAkFAGRN
0 1 K420 IEEELGsKAkFAGRN
0 3 K422-ub EELGskAkFAGRNFR
0 1 R426 skAkFAGRNFRNPLA
0 5 N427 kAkFAGRNFRNPLAk
0 1 K434-ac NFRNPLAk_______
  mouse

 
R5 ___MSILRIHAREIF
R5 ___MSILRIHAREIF
S14 HAREIFDSRGNPTVE
T19 FDSRGNPTVEVDLyt
Y25-p PTVEVDLytAkGLFR
T26-p TVEVDLytAkGLFRA
A27 VEVDLytAkGLFRAA
K28-ac EVDLytAkGLFRAAV
K28-ub EVDLytAkGLFRAAV
S37-p LFRAAVPsGAstGIy
S40-p AAVPsGAstGIyEAL
T41-p AVPsGAstGIyEALE
Y44-p sGAstGIyEALELRD
K54-ac LELRDNDkTRFMGkG
K54-ub LELRDNDkTRFMGkG
T55 ELRDNDkTRFMGkGV
F57 RDNDkTRFMGkGVSQ
K60-ac DkTRFMGkGVSQAVE
K60-ub DkTRFMGkGVSQAVE
Q64 FMGkGVSQAVEHINk
Q64 FMGkGVSQAVEHINk
K71-ac QAVEHINkTIAPALV
K71-ub QAVEHINkTIAPALV
K71 QAVEHINKTIAPALV
T72 AVEHINkTIAPALVs
S79-p TIAPALVskkVNVVE
K80-ac IAPALVskkVNVVEQ
K80-ub IAPALVskkVNVVEQ
K80-sc IAPALVskkVNVVEQ
K81-ac APALVskkVNVVEQE
K81-ub APALVskkVNVVEQE
K89-ac VNVVEQEkIDkLMIE
K89-ub VNVVEQEkIDkLMIE
K92-ac VEQEkIDkLMIEMDG
K92-ub VEQEkIDkLMIEMDG
K92-sc VEQEkIDkLMIEMDG
T100 LMIEMDGTENkSKFG
K103 EMDGTENKSKFGANA
K103-ub EMDGTENkSKFGANA
K105 DGTENkSKFGANAIL
K105 DGTENkSKFGANAIL
K120 GVSLAVCKAGAVEkG
K126-ac CKAGAVEkGVPLYRH
K126 CKAGAVEKGVPLYRH
K126 CKAGAVEKGVPLYRH
Y131 VEkGVPLYRHIADLA
K162-ac GGSHAGNkLAMQEFM
Y189-p MRIGAEVyHNLkNVI
K193-ac AEVyHNLkNVIkEKY
K193-ub AEVyHNLkNVIkEKY
K193-sc AEVyHNLkNVIkEKY
K197-ac HNLkNVIkEKYGkDA
K197 HNLkNVIKEKYGkDA
K199 LkNVIkEKYGkDATN
K202-ac VIkEKYGkDATNVGD
K202-ub VIkEKYGkDATNVGD
K202-sc VIkEKYGkDATNVGD
T205 EKYGkDATNVGDEGG
K221-ac APNILENkEALELLk
K221-ub APNILENkEALELLk
K221-sc APNILENkEALELLk
K228-ac kEALELLkTAIAKAG
K228-ub kEALELLkTAIAKAG
K233 LLkTAIAKAGYTDQV
K233 LLkTAIAKAGYTDQV
Y236 TAIAKAGYTDQVVIG
T237 AIAKAGYTDQVVIGM
Q239 AKAGYTDQVVIGMDV
S254-p AASEFYRsGkYDLDF
K256-ac SEFYRsGkYDLDFks
K256-ub SEFYRsGkYDLDFks
K256 SEFYRsGKYDLDFks
Y257 EFYRsGkYDLDFksP
K262 GkYDLDFKsPDDPsR
K262 GkYDLDFKsPDDPsR
K262-sc GkYDLDFksPDDPsR
S263-p kYDLDFksPDDPsRy
S268-p FksPDDPsRyItPDQ
Y270-p sPDDPsRyItPDQLA
T272-p DDPsRyItPDQLADL
Y280 PDQLADLYKsFVQNy
K281 DQLADLYKsFVQNyP
K281 DQLADLYKsFVQNyP
K281 DQLADLYKsFVQNyP
S282-p QLADLYKsFVQNyPV
Q285 DLYKsFVQNyPVVSI
Q285 DLYKsFVQNyPVVSI
Q285 DLYKsFVQNyPVVSI
Y287-p YKsFVQNyPVVSIED
S291 VQNyPVVSIEDPFDQ
K306 DDWGAWQKFTAsAGI
S310-p AWQKFTAsAGIQVVG
K326-ac DLTVTNPkRIAKAAs
K326-ub DLTVTNPkRIAKAAs
K330 TNPkRIAKAAsEkSC
K330 TNPkRIAKAAsEkSC
K330 TNPkRIAKAAsEkSC
S333-p kRIAKAAsEkSCNCL
K335 IAKAAsEKSCNCLLL
K335-ub IAKAAsEkSCNCLLL
K335 IAKAAsEKSCNCLLL
S336 AKAAsEkSCNCLLLk
K343-ac SCNCLLLkVNQIGsV
K343-ub SCNCLLLkVNQIGsV
S349-p LkVNQIGsVTESLQA
K358 TESLQACKLAQsNGW
K358 TESLQACKLAQsNGW
S362-p QACKLAQsNGWGVMV
S370 NGWGVMVSHRSGETE
K394-ub GLCTGQIkTGAPCRS
K406-ac CRSERLAkYNQILRI
K406-ub CRSERLAkYNQILRI
K406 CRSERLAKYNQILRI
S419-p RIEEELGskAKFAGr
K420 IEEELGsKAKFAGrs
K420-ub IEEELGskAKFAGrs
K420-sc IEEELGskAKFAGrs
K422 EELGskAKFAGrsFR
R426-m1 skAKFAGrsFRNPLA
S427-p kAKFAGrsFRNPLAK
K434 sFRNPLAK_______
  rat

 
K5 ___MSILKIHAREIF
K5 ___MSILKIHAREIF
S14 HAREIFDSRGNPTVE
T19 FDSRGNPTVEVDLYT
Y25 PTVEVDLYTAKGLFR
T26 TVEVDLYTAKGLFRA
A27 VEVDLYTAKGLFRAA
K28 EVDLYTAKGLFRAAV
K28 EVDLYTAKGLFRAAV
S37 LFRAAVPSGAsTGIy
S40-p AAVPSGAsTGIyEAL
T41 AVPSGAsTGIyEALE
Y44-p SGAsTGIyEALELRD
K54 LELRDNDKTRFMGKG
K54 LELRDNDKTRFMGKG
T55 ELRDNDKTRFMGKGV
F57 RDNDKTRFMGKGVSk
K60 DKTRFMGKGVSkAVE
K60 DKTRFMGKGVSkAVE
K64 FMGKGVSKAVEHINK
K64-ub FMGKGVSkAVEHINK
K71 kAVEHINKTIAPALV
K71 kAVEHINKTIAPALV
K71 kAVEHINKTIAPALV
T72 AVEHINKTIAPALVs
S79-p TIAPALVsKKLNVVE
K80 IAPALVsKKLNVVEQ
K80 IAPALVsKKLNVVEQ
K80 IAPALVsKKLNVVEQ
K81 APALVsKKLNVVEQE
K81 APALVsKKLNVVEQE
K89 LNVVEQEKIDQLMIE
K89 LNVVEQEKIDQLMIE
Q92 VEQEKIDQLMIEMDG
Q92 VEQEKIDQLMIEMDG
Q92 VEQEKIDQLMIEMDG
T100 LMIEMDGTENKSKFG
K103 EMDGTENKSKFGANA
K103 EMDGTENKSKFGANA
K105 DGTENKSKFGANAIL
K105 DGTENKSKFGANAIL
K120 GVSLAVCKAGAVEKG
K126 CKAGAVEKGVPLYRH
K126 CKAGAVEKGVPLYRH
K126 CKAGAVEKGVPLYRH
Y131 VEKGVPLYRHIADLA
K162 GGSHAGNKLAMQEFM
Y189 MRIGAEVYHNLKNVI
K193 AEVYHNLKNVIKEKY
K193 AEVYHNLKNVIKEKY
K193 AEVYHNLKNVIKEKY
K197 HNLKNVIKEKYGKDA
K197 HNLKNVIKEKYGKDA
K199 LKNVIKEKYGKDATN
K202 VIKEKYGKDATNVGD
K202 VIKEKYGKDATNVGD
K202 VIKEKYGKDATNVGD
T205 EKYGKDATNVGDEGG
K221 APNILENKEALELLK
K221 APNILENKEALELLK
K221 APNILENKEALELLK
K228 KEALELLKSAIAKAG
K228 KEALELLKSAIAKAG
K233 LLKSAIAKAGYTDQV
K233 LLKSAIAKAGYTDQV
Y236 SAIAKAGYTDQVVIG
T237 AIAKAGYTDQVVIGM
Q239 AKAGYTDQVVIGMDV
A254 AASEFYRAGKYDLDF
K256 SEFYRAGKYDLDFKS
K256 SEFYRAGKYDLDFKS
K256 SEFYRAGKYDLDFKS
Y257 EFYRAGKYDLDFKSP
K262 GKYDLDFKSPDDASR
K262 GKYDLDFKSPDDASR
K262 GKYDLDFKSPDDASR
S263 KYDLDFKSPDDASRY
S268 FKSPDDASRYITPDQ
Y270 SPDDASRYITPDQLA
T272 DDASRYITPDQLADL
Y280 PDQLADLYKSFIKDY
K281 DQLADLYKSFIKDYP
K281 DQLADLYKSFIKDYP
K281 DQLADLYKSFIKDYP
S282 QLADLYKSFIKDYPV
K285 DLYKSFIKDYPVVSI
K285 DLYKSFIKDYPVVSI
K285 DLYKSFIKDYPVVSI
Y287 YKSFIKDYPVVSIED
S291 IKDYPVVSIEDPFDQ
K306 DDWDAWQKFTATAGI
T310 AWQKFTATAGIQVVG
K326 DLTVTNPKRIAKAAG
K326 DLTVTNPKRIAKAAG
K330 TNPKRIAKAAGEKSC
K330 TNPKRIAKAAGEKSC
K330 TNPKRIAKAAGEKSC
G333 KRIAKAAGEKSCNCL
K335 IAKAAGEKSCNCLLL
K335 IAKAAGEKSCNCLLL
K335 IAKAAGEKSCNCLLL
S336 AKAAGEKSCNCLLLK
K343 SCNCLLLKVNQIGSV
K343 SCNCLLLKVNQIGSV
S349 LKVNQIGSVTESLQA
K358 TESLQACKLAQSNGW
K358 TESLQACKLAQSNGW
S362 QACKLAQSNGWGVMV
S370 NGWGVMVSHRSGETE
K394 GLCTGQIKTGAPCRS
K406 CRSERLAKYNQILRI
K406 CRSERLAKYNQILRI
K406 CRSERLAKYNQILRI
S419-p RIEEELGsKAKFAGR
K420 IEEELGsKAKFAGRS
K420 IEEELGsKAKFAGRS
K420 IEEELGsKAKFAGRS
K422 EELGsKAKFAGRSFR
R426 sKAKFAGRSFRNPLA
S427 KAKFAGRSFRNPLAK
K434 SFRNPLAK_______
  chicken

 
K5 ___MSILKIHAREIF
K5 ___MSILKIHAREIF
S14 HAREIFDSRGNPTVE
T19 FDSRGNPTVEVDLYT
Y25 PTVEVDLYTNKGLFR
T26 TVEVDLYTNKGLFRA
N27 VEVDLYTNKGLFRAA
K28 EVDLYTNKGLFRAAV
K28 EVDLYTNKGLFRAAV
S37 LFRAAVPSGASTGIy
S40 AAVPSGASTGIyEAL
T41 AVPSGASTGIyEALE
Y44-p SGASTGIyEALELRD
K54 LELRDNDKTRYLGKG
K54 LELRDNDKTRYLGKG
T55 ELRDNDKTRYLGKGV
Y57 RDNDKTRYLGKGVSK
K60 DKTRYLGKGVSKAVE
K60 DKTRYLGKGVSKAVE
K64 YLGKGVSKAVEHVNK
K64 YLGKGVSKAVEHVNK
K71 KAVEHVNKTIAPALI
K71 KAVEHVNKTIAPALI
K71 KAVEHVNKTIAPALI
T72 AVEHVNKTIAPALIS
S79 TIAPALISKNVNVVE
K80 IAPALISKNVNVVEQ
K80 IAPALISKNVNVVEQ
K80 IAPALISKNVNVVEQ
N81 APALISKNVNVVEQE
N81 APALISKNVNVVEQE
K89 VNVVEQEKIDKLMLE
K89 VNVVEQEKIDKLMLE
K92 VEQEKIDKLMLEMDG
K92 VEQEKIDKLMLEMDG
K92 VEQEKIDKLMLEMDG
T100 LMLEMDGTENKSKFG
K103 EMDGTENKSKFGANA
K103 EMDGTENKSKFGANA
K105 DGTENKSKFGANAIL
K105 DGTENKSKFGANAIL
K120 GVSLAVCKAGAAEKG
K126 CKAGAAEKGVPLYRH
K126 CKAGAAEKGVPLYRH
K126 CKAGAAEKGVPLYRH
Y131 AEKGVPLYRHIADLA
K162 GGSHAGNKLAMQEFM
Y189 MRIGAEVYHNLKNVI
K193 AEVYHNLKNVIKEKY
K193 AEVYHNLKNVIKEKY
K193 AEVYHNLKNVIKEKY
K197 HNLKNVIKEKYGKDA
K197 HNLKNVIKEKYGKDA
K199 LKNVIKEKYGKDATN
K202 VIKEKYGKDATNVGD
K202 VIKEKYGKDATNVGD
K202 VIKEKYGKDATNVGD
T205 EKYGKDATNVGDEGG
K221 APNILENKEALELLK
K221 APNILENKEALELLK
K221 APNILENKEALELLK
K228 KEALELLKTAIGKAG
K228 KEALELLKTAIGKAG
K233 LLKTAIGKAGYSDKV
K233 LLKTAIGKAGYSDKV
Y236 TAIGKAGYSDKVVIG
S237 AIGKAGYSDKVVIGM
K239 GKAGYSDKVVIGMDV
D254 AASEFYRDGKYDLDF
K256 SEFYRDGKYDLDFKS
K256 SEFYRDGKYDLDFKS
K256 SEFYRDGKYDLDFKS
Y257 EFYRDGKYDLDFKSP
K262 GKYDLDFKSPDDPSR
K262 GKYDLDFKSPDDPSR
K262 GKYDLDFKSPDDPSR
S263 KYDLDFKSPDDPSRY
S268 FKSPDDPSRYISPDQ
Y270 SPDDPSRYISPDQLA
S272 DDPSRYISPDQLADL
Y280 PDQLADLYLGFVKNY
L281 DQLADLYLGFVKNYP
L281 DQLADLYLGFVKNYP
L281 DQLADLYLGFVKNYP
G282 QLADLYLGFVKNYPV
K285 DLYLGFVKNYPVVSI
K285 DLYLGFVKNYPVVSI
K285 DLYLGFVKNYPVVSI
Y287 YLGFVKNYPVVSIED
S291 VKNYPVVSIEDPFDQ
K306 DDWAAWKKFTASVGI
S310 AWKKFTASVGIQVVG
K326 DLTVTNPKRIAKAVE
K326 DLTVTNPKRIAKAVE
K330 TNPKRIAKAVEEKSC
K330 TNPKRIAKAVEEKSC
K330 TNPKRIAKAVEEKSC
E333 KRIAKAVEEKSCNCL
K335 IAKAVEEKSCNCLLL
K335 IAKAVEEKSCNCLLL
K335 IAKAVEEKSCNCLLL
S336 AKAVEEKSCNCLLLK
K343 SCNCLLLKVNQIGSV
K343 SCNCLLLKVNQIGSV
S349 LKVNQIGSVTESLQA
K358 TESLQACKLAQSNGW
K358 TESLQACKLAQSNGW
S362 QACKLAQSNGWGVMV
S370 NGWGVMVSHRSGETE
K394 GLCTGQIKTGAPCRS
K406 CRSERLAKYNQLLRI
K406 CRSERLAKYNQLLRI
K406 CRSERLAKYNQLLRI
S419 RIEEELGSKARFAGR
K420 IEEELGSKARFAGRN
K420 IEEELGSKARFAGRN
K420 IEEELGSKARFAGRN
R422 EELGSKARFAGRNFR
R426 SKARFAGRNFRNPRI
N427 KARFAGRNFRNPRIN
N434 NFRNPRIN_______
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