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Protein Page:
PLA2G2F (human)

Overview
PLA2G2F PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference. Belongs to the phospholipase A2 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Secreted; Phospholipase; EC 3.1.1.4; Lipid Metabolism - arachidonic acid; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - linoleic acid; Lipid Metabolism - glycerophospholipid; Secreted, signal peptide; Lipid Metabolism - ether lipid
Cellular Component: extracellular region; cytosol
Molecular Function: phospholipase A2 activity; calcium ion binding
Biological Process: biological_process; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; lipid catabolic process
Reference #:  Q9BZM2 (UniProtKB)
Alt. Names/Synonyms: GIIF sPLA2; Group IIF secretory phospholipase A2; PA2GF; Phosphatidylcholine 2-acylhydrolase 2F; RP3-340N1.1; sPLA2-IIF
Gene Symbols: PLA2G2F
Molecular weight: 18,658 Da
Basal Isoelectric point: 5.09  Predict pI for various phosphorylation states
Select Structure to View Below

PLA2G2F

Protein Structure Not Found.


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Modification Sites and Domains  

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