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Protein Page:
FLNA (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
FLNA a ubiquitous cytoskeletal protein that promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Plays an essential role in embryonic cell migration. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interactions with filamin A may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Nuclear receptor co-regulator; Actin binding protein
Cellular Component: cytoplasm; plasma membrane; extracellular region; cell cortex; trans-Golgi network; cytosol; nucleus; actin cytoskeleton
Molecular Function: actin filament binding; small GTPase binding; protein binding; signal transducer activity; Rho GTPase binding; protein homodimerization activity; protein kinase C binding; Rac GTPase binding; Ral GTPase binding; glycoprotein binding; transcription factor binding
Biological Process: actin crosslink formation; platelet activation; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein stabilization; negative regulation of transcription factor activity; receptor clustering; dopamine receptor, adenylate cyclase inhibiting pathway; establishment of protein localization; platelet degranulation; early endosome to late endosome transport; actin cytoskeleton reorganization; positive regulation of transcription factor import into nucleus; cytoplasmic sequestering of protein; epithelial to mesenchymal transition; cilium biogenesis; blood coagulation; negative regulation of protein catabolic process
Reference #:  P21333 (UniProtKB)
Alt. Names/Synonyms: ABP-280; ABPX; actin binding protein 280; Actin-binding protein 280; Alpha-filamin; DKFZp434P031; Endothelial actin-binding protein; filamin 1; filamin A, alpha; Filamin-1; Filamin-A; FLN; FLN-A; FLN1; FLNA; FMD; MNS; NHBP; Non-muscle filamin; OPD; OPD1; OPD2
Gene Symbols: FLNA
Molecular weight: 280,739 Da
Basal Isoelectric point: 5.7  Predict pI for various phosphorylation states
CST Pathways:  MAPK/Erk in Growth and Differentiation  |  Regulation of Actin Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

FLNA
Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  Phospho3D  |  DISEASE  |  Source  |  NURSA  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Sites Implicated In
cytoskeletal reorganization: S2152‑p, S2523‑p
intracellular localization: S2523‑p
protein stabilization: S2152‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

► Hide Isoforms 		 
0 1 S2-p ______MsssHsRAG
0 1 S3-p _____MsssHsRAGQ
0 1 S4-p ____MsssHsRAGQs
0 1 S6-p __MsssHsRAGQsAA
0 2 S11-p sHsRAGQsAAGAAPG
0 3 A16 GQsAAGAAPGGGVDt
0 3 G20 AGAAPGGGVDtRDAE
0 1 T23-p APGGGVDtRDAEMPA
0 1 T31-p RDAEMPAtEKDLAED
0 6 K42-a LAEDAPWkkIQQNTF
0 4 K43-u AEDAPWkkIQQNTFT
0 1 T69-p KRIANLQtDLSDGLR
0 3 K87-u LLEVLSQkkMHRkHN
0 1 K88-u LEVLSQkkMHRkHNQ
0 1 K92-u SQkkMHRkHNQRPTF
0 1 K120 FLDRESIKLVSIDSK
0 1 K169-a EAKKQTPkQRLLGWI
0 1 Y287-p NPKKARAyGPGIEPT
0 2 K299-u EPTGNMVkKRAEFTV
0 1 K299-s EPTGNMVkKRAEFTV
0 9 Y319-p GQGEVLVyVEDPAGH
0 1 K331 AGHQEEAKVtANNDK
0 1 T333-p HQEEAKVtANNDKNR
1 1 S343 NDKNRTFSVWYVPEV
0 1 K367-u FAGQHIAksPFEVyV
0 1 S368-p AGQHIAksPFEVyVD
0 69 Y373-p AksPFEVyVDksQGD
0 4 K376-u PFEVyVDksQGDAsk
0 1 S377-p FEVyVDksQGDAskV
0 2 S382-p DksQGDAskVTAQGP
0 2 K383-u ksQGDAskVTAQGPG
0 1 T385 QGDAskVTAQGPGLE
0 5 Y403-p NIANKTTyFEIFTAG
0 3 T500-p KGVRVKEtADFkVyt
0 1 K504-a VKEtADFkVytkGAG
0 1 K504-u VKEtADFkVytkGAG
0 62 Y506-p EtADFkVytkGAGsG
0 6 T507-p tADFkVytkGAGsGE
0 1 K508-a ADFkVytkGAGsGEL
0 1 K508 ADFkVytKGAGsGEL
0 1 S512-p VytkGAGsGELKVTV
0 11 Y538-p KDLGDGVyGFEYYPM
0 31 K578-a GTECGNQkVRAWGPG
0 1 Y643-p WPQEAGEyAVHVLCN
0 1 K691 KTGVAVNKPAEFTVD
0 3 K700-a AEFTVDAkHGGKAPL
0 2 T730-p VKDNGNGtysCsyVP
0 86 Y731-p KDNGNGtysCsyVPR
0 17 S732-p DNGNGtysCsyVPRK
0 2 S734-p GNGtysCsyVPRKPV
0 2 Y735-p NGtysCsyVPRKPVK
0 1 S753-p MVSWGGVsIPNsPFR
0 1 S757-p GGVsIPNsPFRVNVG
0 2 S767-p RVNVGAGsHPNkVkV
0 3 K771-a GAGsHPNkVkVyGPG
0 2 K773-u GsHPNkVkVyGPGVA
0 29 Y775-p HPNkVkVyGPGVAkt
0 1 K781-a VyGPGVAktGLKAHE
0 4 K781-u VyGPGVAktGLKAHE
0 1 T782-p yGPGVAktGLKAHEP
0 1 T790-p GLKAHEPtyFtVDCA
0 11 Y791-p LKAHEPtyFtVDCAE
0 5 T793-p AHEPtyFtVDCAEAG
0 1 K837-a DNDTFTVkYTPRGAG
0 1 K837-u DNDTFTVkYTPRGAG
0 7 S860-p ADQATPTsPIRVkVE
0 2 K865-u PTsPIRVkVEPSHDA
0 1 K874-a EPSHDASkVKAEGPG
0 1 K891-a RTGVELGkPTHFTVN
0 1 K900 THFTVNAKAAGKGkL
0 3 K906-u AKAAGKGkLDVQFsG
0 1 S912-p GkLDVQFsGLtkGDA
0 1 T915-p DVQFsGLtkGDAVRD
0 1 K916-u VQFsGLtkGDAVRDV
0 1 S959 GGDPIPKSPFSVAVs
0 2 S966-p SPFSVAVsPsLDLsk
0 8 S968-p FSVAVsPsLDLskIK
0 1 S972-p VsPsLDLskIKVSGL
0 1 K973-a sPsLDLskIKVSGLG
0 1 K994-a KDQEFTVkSKGAGGQ
0 1 K1003-u KGAGGQGkVASKIVG
0 2 G1010 kVASKIVGPSGAAVP
0 5 K1019-u SGAAVPCkVEPGLGA
0 1 Y1047-p PYEVEVTydGVPVPG
0 1 D1048-ca YEVEVTydGVPVPGs
0 4 S1055-p dGVPVPGsPFPLEAV
0 2 K1071-a PTKPSKVkAFGPGLQ
0 3 K1071-u PTKPSKVkAFGPGLQ
0 7 S1081-p GPGLQGGsAGsPARF
0 29 S1084-p LQGGsAGsPARFTID
0 2 S1161-p VVPCFDAskVkCSGP
0 2 K1162-u VPCFDAskVkCSGPG
0 2 K1164-u CFDAskVkCSGPGLE
0 41 Y1261-p DTSGVQCyGPGIEGQ
0 1 T1286-p SVDARALtQTGGPHV
0 1 K1294 QTGGPHVKARVANPS
0 1 T1307-p PSGNLTEtyVQDRGD
0 16 Y1308-p SGNLTEtyVQDRGDG
0 1 T1334-p GLHSVDVtYdGsPVP
0 1 D1336-ca HSVDVtYdGsPVPSs
0 4 S1338-p VDVtYdGsPVPSsPF
0 2 S1343-p dGsPVPSsPFQVPVT
0 1 T1377-p TNKPNKFtVETRGAG
1 2 S1436-p GGHQVPGsPFKVPVH
0 1 T1446-p KVPVHDVtDAsKVKC
0 1 S1449-p VHDVtDAsKVKCsGP
0 1 S1454-p DAsKVKCsGPGLsPG
1 41 S1459-p KCsGPGLsPGMVRAN
0 2 S1470-p VRANLPQsFQVDtsk
0 2 T1475-p PQsFQVDtskAGVAP
0 1 S1476-p QsFQVDtskAGVAPL
0 6 K1477-u sFQVDtskAGVAPLQ
0 2 K1491-u QVKVQGPkGLVEPVD
0 1 D1504-ca VDVVDNAdGTQTVNY
0 1 S1514 QTVNYVPSREGPYSI
1 3 P1518 YVPSREGPYSISVLY
1 12 S1533-p GDEEVPRsPFKVkVL
0 1 K1538-a PRsPFKVkVLPTHDA
0 4 K1538-u PRsPFKVkVLPTHDA
0 1 T1542 FKVkVLPTHDAsKVK
0 1 S1546-p VLPTHDAsKVKASGP
0 1 K1590-u QITDPEGkPKKtHIQ
0 1 T1594-p PEGkPKKtHIQDNHD
0 14 T1603-p IQDNHDGtytVAYVP
0 433 Y1604-p QDNHDGtytVAYVPD
0 53 T1605-p DNHDGtytVAYVPDV
0 1 K1621-u GRYTILIkYGGDEIP
1 17 S1630-p GGDEIPFsPyRVRAV
0 2 Y1632-p DEIPFsPyRVRAVPT
0 1 Y1720-p TAPQPGKyVICVRFG
0 4 S1734-p GGEHVPNsPFQVtAL
0 2 T1739-p PNsPFQVtALAGDQP
0 9 P1750 GDQPSVQPPLRSQQL
0 4 Y1761-p SQQLAPQytyAQGGQ
0 6 T1762-p QQLAPQytyAQGGQQ
0 10 Y1763-p QLAPQytyAQGGQQT
0 2 K1801-u VIPFTIKkGEITGEV
0 4 K1824-u QPTITDNkDGTVTVR
0 2 Y1862-p PLQFYVDyVNCGHVT
0 4 Y1871-p NCGHVTAyGPGLTHG
0 1 Y1932-p LPVLPGDySILVKyN
0 1 Y1938-p DySILVKyNEQHVPG
0 1 S1946-p NEQHVPGsPFTARVT
0 1 S1957 ARVTGDDSMRMSHLk
0 1 S1961 GDDSMRMSHLkVGSA
0 2 K1964-u SMRMSHLkVGSAADI
0 1 S1976 ADIPINISETDLSLL
0 1 K2000-a REEPCLLkRLRNGHV
0 2 S2053-p DASRVRVsGQGLHEG
0 1 T2062-p QGLHEGHtFEPAEFI
0 1 S2088-p SLSIEGPsKVDINTE
0 12 S2128-p ADQHVPGsPFSVKVt
0 1 T2135-p sPFSVKVtGEGRVKE
0 1 S2143-p GEGRVKEsITRRRRA
10 959 S2152-p TRRRRAPsVANVGsH
0 102 S2158-p PsVANVGsHCDLsLK
0 4 S2163-p VGsHCDLsLKIPEIS
0 2 S2170 sLKIPEISIQDMTAQ
0 5 S2180-p DMTAQVTsPSGKTHE
0 1 T2197-p IVEGENHtyCIRFVP
0 14 Y2198-p VEGENHtyCIRFVPA
0 1 K2217-u HTVSVKYkGQHVPGs
0 1 S2224-p kGQHVPGsPFQFTVG
0 3 S2284-p GPSKAEIsFEDRKDG
1 0 S2292-p FEDRKDGsCGVAYVV
0 2 Y2305-p VVQEPGDyEVSVKFN
0 4 S2319-p NEEHIPDsPFVVPVA
0 10 S2327-p PFVVPVAsPSGDARR
0 2 S2329 VVPVAsPSGDARRLt
1 27 T2336-p SGDARRLtVsSLQES
0 1 S2338-p DARRLtVsSLQESGL
0 1 K2361-u AVSLNGAkGAIDAKV
1 2 S2370-p AIDAKVHsPsGALEE
0 2 S2372-p DAKVHsPsGALEECy
0 27 Y2379-p sGALEECyVtEIDQD
0 11 T2381-p ALEECyVtEIDQDKy
0 373 Y2388-p tEIDQDKyAVRFIPR
0 1 Y2400-p IPRENGVyLIDVKFN
0 8 S2414-p NGTHIPGsPFkIRVG
0 1 K2417-a HIPGsPFkIRVGEPG
0 1 K2417-u HIPGsPFkIRVGEPG
0 1 K2473-u IDGPSKVkMDCQECP
0 1 Y2483-p CQECPEGyRVTYTPM
0 1 Y2505-p SIKYGGPyHIGGsPF
0 7 S2510-p GPyHIGGsPFKAKVT
2 2 S2523-p VTGPRLVsNHsLHET
0 1 S2526-p PRLVsNHsLHETSSV
0 33 T2599-p VGVHGPRtPCEEILV
0 1 K2607-a PCEEILVkHVGSRLy
0 6 Y2614-p kHVGSRLySVSyLLk
1 2 S2615 HVGSRLySVSyLLkD
0 1 S2617 GSRLySVSyLLkDkG
0 1 Y2618-p SRLySVSyLLkDkGE
0 1 K2621-a ySVSyLLkDkGEYTL
0 2 K2623-a VSyLLkDkGEYTLVV
0 2 Y2642-p EHIPGSPyRVVVP__
4761 : Phospho-Filamin A (Ser2152) Antibody
  FLNA iso2  
S2 ______MSSSHSRAG
S3 _____MSSSHSRAGQ
S4 ____MSSSHSRAGQS
S6 __MSSSHSRAGQSAA
S11 SHSRAGQSAAGAAPG
A16 GQSAAGAAPGGGVDT
G20 AGAAPGGGVDTRDAE
T23 APGGGVDTRDAEMPA
T31 RDAEMPATEKDLAED
K42 LAEDAPWKKIQQNTF
K43 AEDAPWKKIQQNTFT
T69 KRIANLQTDLSDGLR
K87 LLEVLSQKKMHRKHN
K88 LEVLSQKKMHRKHNQ
K92 SQKKMHRKHNQRPTF
K120 FLDRESIKLVSIDSK
K169 EAKKQTPKQRLLGWI
Y287 NPKKARAYGPGIEPT
K299 EPTGNMVKKRAEFTV
K299 EPTGNMVKKRAEFTV
Y319 GQGEVLVYVEDPAGH
K331 AGHQEEAKVTANNDK
T333 HQEEAKVTANNDKNR
S343 NDKNRTFSVWYVPEV
K367 FAGQHIAKSPFEVYV
S368 AGQHIAKSPFEVYVD
Y373 AKSPFEVYVDKSQGD
K376 PFEVYVDKSQGDASK
S377 FEVYVDKSQGDASKV
S382 DKSQGDASKVTAQGP
K383 KSQGDASKVTAQGPG
T385 QGDASKVTAQGPGLE
Y403 NIANKTTYFEIFTAG
T500 KGVRVKETADFKVYT
K504 VKETADFKVYTKGAG
K504 VKETADFKVYTKGAG
Y506 ETADFKVYTKGAGSG
T507 TADFKVYTKGAGSGE
K508 ADFKVYTKGAGSGEL
K508 ADFKVYTKGAGSGEL
S512 VYTKGAGSGELKVTV
Y538 KDLGDGVYGFEYYPM
K578 GTECGNQKVRAWGPG
Y643 WPQEAGEYAVHVLCN
K691 KTGVAVNKPAEFTVD
K700 AEFTVDAKHGGKAPL
T730 VKDNGNGTYSCSYVP
Y731 KDNGNGTYSCSYVPR
S732 DNGNGTYSCSYVPRK
S734 GNGTYSCSYVPRKPV
Y735 NGTYSCSYVPRKPVK
S753 MVSWGGVSIPNSPFR
S757 GGVSIPNSPFRVNVG
S767 RVNVGAGSHPNKVKV
K771 GAGSHPNKVKVYGPG
K773 GSHPNKVKVYGPGVA
Y775 HPNKVKVYGPGVAKT
K781 VYGPGVAKTGLKAHE
K781 VYGPGVAKTGLKAHE
T782 YGPGVAKTGLKAHEP
T790 GLKAHEPTYFTVDCA
Y791 LKAHEPTYFTVDCAE
T793 AHEPTYFTVDCAEAG
K837 DNDTFTVKYTPRGAG
K837 DNDTFTVKYTPRGAG
S860 ADQATPTSPIRVKVE
K865 PTSPIRVKVEPSHDA
K874 EPSHDASKVKAEGPG
K891 RTGVELGKPTHFTVN
K900 THFTVNAKAAGKGKL
K906 AKAAGKGKLDVQFSG
S912 GKLDVQFSGLTKGDA
T915 DVQFSGLTKGDAVRD
K916 VQFSGLTKGDAVRDV
S959 GGDPIPKSPFSVAVS
S966 SPFSVAVSPSLDLSK
S968 FSVAVSPSLDLSKIK
S972 VSPSLDLSKIKVSGL
K973 SPSLDLSKIKVSGLG
K994 KDQEFTVKSKGAGGQ
K1003 KGAGGQGKVASKIVG
G1010 KVASKIVGPSGAAVP
K1019 SGAAVPCKVEPGLGA
Y1047 PYEVEVTYDGVPVPG
D1048 YEVEVTYDGVPVPGS
S1055 DGVPVPGSPFPLEAV
K1071 PTKPSKVKAFGPGLQ
K1071 PTKPSKVKAFGPGLQ
S1081 GPGLQGGSAGSPARF
S1084 LQGGSAGSPARFTID
S1161 VVPCFDASKVKCSGP
K1162 VPCFDASKVKCSGPG
K1164 CFDASKVKCSGPGLE
Y1261 DTSGVQCYGPGIEGQ
T1286 SVDARALTQTGGPHV
K1294 QTGGPHVKARVANPS
T1307 PSGNLTETYVQDRGD
Y1308 SGNLTETYVQDRGDG
T1334 GLHSVDVTYDGSPVP
D1336 HSVDVTYDGSPVPSS
S1338 VDVTYDGSPVPSSPF
S1343 DGSPVPSSPFQVPVT
T1377 TNKPNKFTVETRGAG
S1436 GGHQVPGSPFKVPVH
T1446 KVPVHDVTDASKVKC
S1449 VHDVTDASKVKCSGP
S1454 DASKVKCSGPGLSPG
S1459 KCSGPGLSPGMVRAN
S1470 VRANLPQSFQVDTSK
T1475 PQSFQVDTSKAGVAP
S1476 QSFQVDTSKAGVAPL
K1477 SFQVDTSKAGVAPLQ
K1491 QVKVQGPKGLVEPVD
D1504 VDVVDNADGTQTVNY
S1514 QTVNYVPSREGPYSI
P1518 YVPSREGPYSISVLY
S1533 GDEEVPRSPFKVKVL
K1538 PRSPFKVKVLPTHDA
K1538 PRSPFKVKVLPTHDA
T1542 FKVKVLPTHDASKVK
S1546 VLPTHDASKVKASGP
K1590 QITDPEGKPKKTHIQ
T1594 PEGKPKKTHIQDNHD
T1603 IQDNHDGTYTVAYVP
Y1604 QDNHDGTYTVAYVPD
T1605 DNHDGTYTVAYVPDV
K1621 GRYTILIKYGGDEIP
S1630 GGDEIPFSPYRVRAV
Y1632 DEIPFSPYRVRAVPT
Y1712 TAPQPGKYVICVRFG
S1726 GGEHVPNSPFQVTAL
T1731 PNSPFQVTALAGDQP
P1742 GDQPSVQPPLRSQQL
Y1753 SQQLAPQYTYAQGGQ
T1754 QQLAPQYTYAQGGQQ
Y1755 QLAPQYTYAQGGQQT
K1793 VIPFTIKKGEITGEV
K1816 QPTITDNKDGTVTVR
Y1854 PLQFYVDYVNCGHVT
Y1863 NCGHVTAYGPGLTHG
Y1924 LPVLPGDYSILVKYN
Y1930 DYSILVKYNEQHVPG
S1938 NEQHVPGSPFTARVT
S1949 ARVTGDDSMRMSHLK
S1953 GDDSMRMSHLKVGSA
K1956 SMRMSHLKVGSAADI
S1968 ADIPINISETDLSLL
K1992 REEPCLLKRLRNGHV
S2045 DASRVRVSGQGLHEG
T2054 QGLHEGHTFEPAEFI
S2080 SLSIEGPSKVDINTE
S2120 ADQHVPGSPFSVKVT
T2127 SPFSVKVTGEGRVKE
S2135 GEGRVKESITRRRRA
S2144 TRRRRAPSVANVGSH
S2150 PSVANVGSHCDLSLK
S2155 VGSHCDLSLKIPEIS
S2162 SLKIPEISIQDMTAQ
S2172 DMTAQVTSPSGKTHE
T2189 IVEGENHTYCIRFVP
Y2190 VEGENHTYCIRFVPA
K2209 HTVSVKYKGQHVPGS
S2216 KGQHVPGSPFQFTVG
S2276 GPSKAEISFEDRKDG
S2284 FEDRKDGSCGVAYVV
Y2297 VVQEPGDYEVSVKFN
S2311 NEEHIPDSPFVVPVA
S2319 PFVVPVASPSGDARR
S2321 VVPVASPSGDARRLT
T2328 SGDARRLTVSSLQES
S2330 DARRLTVSSLQESGL
K2353 AVSLNGAKGAIDAKV
S2362 AIDAKVHSPSGALEE
S2364 DAKVHSPSGALEECY
Y2371 SGALEECYVTEIDQD
T2373 ALEECYVTEIDQDKY
Y2380 TEIDQDKYAVRFIPR
Y2392 IPRENGVYLIDVKFN
S2406 NGTHIPGSPFKIRVG
K2409 HIPGSPFKIRVGEPG
K2409 HIPGSPFKIRVGEPG
K2465 IDGPSKVKMDCQECP
Y2475 CQECPEGYRVTYTPM
Y2497 SIKYGGPYHIGGSPF
S2502 GPYHIGGSPFKAKVT
S2515 VTGPRLVSNHSLHET
S2518 PRLVSNHSLHETSSV
T2591 VGVHGPRTPCEEILV
K2599 PCEEILVKHVGSRLY
Y2606 KHVGSRLYSVSYLLK
S2607 HVGSRLYSVSYLLKD
S2609 GSRLYSVSYLLKDKG
Y2610 SRLYSVSYLLKDKGE
K2613 YSVSYLLKDKGEYTL
K2615 VSYLLKDKGEYTLVV
Y2634 EHIPGSPYRVVVP__
  mouse

 
S2 ______MSSSHSRCG
S3 _____MSSSHSRCGQ
S4 ____MSSSHSRCGQS
S6 __MSSSHSRCGQSAA
S11 SHSRCGQSAAVAsPG
S16-p GQSAAVAsPGGsIDS
S20-p AVAsPGGsIDSRDAE
S23 sPGGsIDSRDAEMPA
T31 RDAEMPATEKDLAED
K42-a LAEDAPWkkIQQNTF
K43-u AEDAPWkkIQQNTFT
T69-p KRIANLQtDLSDGLR
K87-u LLEVLSQkKMHRKHN
K88 LEVLSQkKMHRKHNQ
K92 SQkKMHRKHNQRPTF
K120-a FLDRESIkLVSIDSK
K169 EAKKQTPKQRLLGWI
Y287 NPKKARAYGPGIEPT
K299 EPTGNMVKKRAEFTV
K299 EPTGNMVKKRAEFTV
Y319 GQGEVLVYVEDPAGH
K331-a AGHQEEAkVTANNDK
T333 HQEEAkVTANNDKNR
S343 NDKNRTFSVWYVPEV
K367 FAGQHIAKSPFEVyV
S368 AGQHIAKSPFEVyVD
Y373-p AKSPFEVyVDKSQGD
K376 PFEVyVDKSQGDAsK
S377 FEVyVDKSQGDAsKV
S382-p DKSQGDAsKVtAQGP
K383 KSQGDAsKVtAQGPG
T385-p QGDAsKVtAQGPGLE
Y403 NIANKTTYFEIFTAG
T500 KGVRVKETADFKVYT
K504 VKETADFKVYTkGAG
K504 VKETADFKVYTkGAG
Y506 ETADFKVYTkGAGSG
T507 TADFKVYTkGAGSGE
K508 ADFKVYTKGAGSGEL
K508-u ADFKVYTkGAGSGEL
S512 VYTkGAGSGELKVTV
Y538 KDLGDGVYGFEYYPT
K578-a GTECGNQkVRAWGPG
Y643 WPQEAGEYAVHVLCN
K691-a KTGVAVNkPAEFTVD
K700 AEFTVDAKHAGKAPL
T730 VKDNGNGTYSCSyVP
Y731 KDNGNGTYSCSyVPR
S732 DNGNGTYSCSyVPRK
S734 GNGTYSCSyVPRKPV
Y735-p NGTYSCSyVPRKPVK
S753 MVSWGGVSIPNSPFR
S757 GGVSIPNSPFRVNVG
S767 RVNVGAGSHPNKVKV
K771 GAGSHPNKVKVyGPG
K773 GSHPNKVKVyGPGVA
Y775-p HPNKVKVyGPGVAKT
K781 VyGPGVAKTGLKAHE
K781 VyGPGVAKTGLKAHE
T782 yGPGVAKTGLKAHEP
T790 GLKAHEPTYFTVDCT
Y791 LKAHEPTYFTVDCTE
T793 AHEPTYFTVDCTEAG
K837 DNDTFTVKYTPCGAG
K837 DNDTFTVKYTPCGAG
S860 ADQATPTSPIRVKVE
K865 PTSPIRVKVEPSHDA
K874 EPSHDASKVKAEGPG
K891 RTGVELGKPTHFTVN
K900-u THFTVNAkTAGKGKL
K906 AkTAGKGKLDVQFSG
S912 GKLDVQFSGLAKGDA
A915 DVQFSGLAKGDAVRD
K916 VQFSGLAKGDAVRDV
S959-p GGDHIPKsPFSVGVS
S966 sPFSVGVSPsLDLSK
S968-p FSVGVSPsLDLSKIK
S972 VSPsLDLSKIKVSGL
K973 SPsLDLSKIKVSGLG
K994 KDQEFTVKSKGAGGQ
K1003 KGAGGQGKVASKIVs
S1010-p KVASKIVsPSGAAVP
K1019 SGAAVPCKVEPGLGA
Y1047 PYEVEVTYDGVPVPG
D1048 YEVEVTYDGVPVPGs
S1055-p DGVPVPGsPFPLEAV
K1071 PTKPSKVKAFGPGLQ
K1071-u PTKPSKVkAFGPGLQ
N1081 GPGLQGGNAGsPARF
S1084-p LQGGNAGsPARFTID
S1161-p VAPCFDAsKVKCSGP
K1162 APCFDAsKVKCSGPG
K1164 CFDAsKVKCSGPGLE
Y1261 DTSGVQCYGPGIEGQ
T1286 SVDARALTQTGGPHV
K1294-u QTGGPHVkARVANPS
T1307 PSGNLTDTYVQDCGD
Y1308 SGNLTDTYVQDCGDG
T1334 GVHSVDVTYDGsPVP
D1336 HSVDVTYDGsPVPSS
S1338-p VDVTYDGsPVPSSPF
S1343 DGsPVPSSPFQVPVT
T1377 TNKPNKFTVETRGAG
S1436 GGHQVPGSPFKVPVH
T1446 KVPVHDVTDASKVKC
S1449 VHDVTDASKVKCSGP
S1454 DASKVKCSGPGLsPG
S1459-p KCSGPGLsPGMVRAN
S1470 VRANLPQSFQVDTSk
T1475 PQSFQVDTSkAGVAP
S1476 QSFQVDTSkAGVAPL
K1477-u SFQVDTSkAGVAPLQ
K1491-u QVKVQGPkGLVEPVD
D1504 VDVVDNADGTQTVNY
S1514-p QTVNYVPsREGsYSI
S1518-p YVPsREGsYSISVLY
S1533-p GEEEVPRsPFKVKVL
K1538 PRsPFKVKVLPtHDA
K1538 PRsPFKVKVLPtHDA
T1542-p FKVKVLPtHDASKVK
S1546 VLPtHDASKVKASGP
K1590 QITDPEGKPKKTHIQ
T1594 PEGKPKKTHIQDNHD
T1603 IQDNHDGTYTVAYVP
Y1604 QDNHDGTYTVAYVPD
T1605 DNHDGTYTVAYVPDV
K1621 GRYTILIKYGGDEIP
S1630-p GGDEIPFsPyRVRAV
Y1632-p DEIPFsPyRVRAVPT
Y1720 TAPQPGKYVICVRFG
S1734-p GGEHVPNsPFQVtAL
T1739-p PNsPFQVtALAGDQP
T1750-p GDQPTVQtPLRSQQL
Y1761 SQQLAPQYNYPQGSQ
N1762 QQLAPQYNYPQGSQQ
Y1763 QLAPQYNYPQGSQQT
K1801 VIPFTIKKGEITGEV
K1824-u QPSITDNkDGTVTVR
Y1862 PLQFYVDYVNCGHIT
Y1871 NCGHITAYGPGLTHG
Y1932 LPVLPGDYSILVKYN
Y1938 DYSILVKYNDQHIPG
S1946 NDQHIPGSPFTARVT
S1957-p ARVTGDDsMRMsHLK
S1961-p GDDsMRMsHLKVGSA
K1964 sMRMsHLKVGSAADI
S1976-p ADIPINIsETDLSLL
K2000 REEPCLLKRLRNGHV
S2053 DASRVRVSGQGLHEG
T2062 QGLHEGHTFEPAEFI
S2088 SLSIEGPSKVDINTE
S2128-p ADQHVPGsPFSVKVT
T2135 sPFSVKVTGEGRVKE
S2143-p GEGRVKEsITRRRRA
S2152-p TRRRRAPsVANIGsH
S2158-p PsVANIGsHCDLsLK
S2163-p IGsHCDLsLKIPEIs
S2170-p sLKIPEIsIQDMTAQ
S2180-p DMTAQVTsPSGKTHE
T2197 IVEGENHTYCIRFVP
Y2198 VEGENHTYCIRFVPA
K2217 HTVSVKYKGQHVPGS
S2224 KGQHVPGSPFQFTVG
S2284-p GPSKAEIsFEDRKDG
S2292 FEDRKDGSCGVAYVV
Y2305-p VVQEPGDyEVSVKFN
S2319-p NEEHIPDsPFVVPVA
S2327-p PFVVPVAsPsGDARR
S2329-p VVPVAsPsGDARRLt
T2336-p sGDARRLtVSSLQES
S2338 DARRLtVSSLQESGL
K2361 AVSLNGAKGAIDAKV
S2370-p AIDAKVHsPsGALEE
S2372-p DAKVHsPsGALEECy
Y2379-p sGALEECyVTEIDQD
T2381 ALEECyVTEIDQDKY
Y2388 TEIDQDKYAVRFIPR
Y2400 IPRENGIYLIDVKFN
S2414-p NGTHIPGsPFKIRVG
K2417 HIPGsPFKIRVGEPG
K2417 HIPGsPFKIRVGEPG
K2473 IDGPSKVKMDCQECP
Y2483 CQECPEGYRVTYTPM
Y2505 SIKYGGPYHIGGsPF
S2510-p GPYHIGGsPFKAKVT
S2523-p VTGPRLVsNHsLHET
S2526-p PRLVsNHsLHETSSV
T2599-p VGVHGPRtPCEEILV
K2607 PCEEILVKHMGSRLY
Y2614 KHMGSRLYsVsYLLK
S2615-p HMGSRLYsVsYLLKD
S2617-p GSRLYsVsYLLKDKG
Y2618 SRLYsVsYLLKDKGE
K2621 YsVsYLLKDKGEYTL
K2623 VsYLLKDKGEYTLVV
Y2642 EHIPGSPYRIMVP__
4761 : Phospho-Filamin A (Ser2152) Antibody
  rat

 
S2 ______MSSSHSRSG
S3 _____MSSSHSRSGQ
S4 ____MSSSHSRSGQS
S6 __MSSSHSRSGQSAA
S11 SHSRSGQSAAGASPA
S16 GQSAAGASPAGGIDT
G20 AGASPAGGIDTRDAE
T23 SPAGGIDTRDAEMPA
T31 RDAEMPATEKDLAED
K42 LAEDAPWKKIQQNTF
K43 AEDAPWKKIQQNTFT
T69 KRIANLQTDLSDGLR
K87 LLEVLSQKKMHRKHN
K88 LEVLSQKKMHRKHNQ
K92 SQKKMHRKHNQRPTF
K120 FLDRESIKLVSIDSK
K169 EAKKQTPKQRLLGWI
Y287 NPKKARAYGPGIEPT
K299 EPTGNMVKKRAEFTV
K299 EPTGNMVKKRAEFTV
Y319 GQGEVLVYVEDPAGH
K331 AGHQEEAKVTANNDK
T333 HQEEAKVTANNDKNR
S343-p NDKNRTFsVWYVPEV
K367 FAGQHIAKSPFEVYV
S368 AGQHIAKSPFEVYVD
Y373 AKSPFEVYVDKSQGD
K376 PFEVYVDKSQGDASK
S377 FEVYVDKSQGDASKV
S382 DKSQGDASKVTAQGP
K383 KSQGDASKVTAQGPG
T385 QGDASKVTAQGPGLE
Y403 NIANKTTYFEIFTAG
T500 KGVRVKETADFKVYT
K504 VKETADFKVYTKGAG
K504 VKETADFKVYTKGAG
Y506 ETADFKVYTKGAGSG
T507 TADFKVYTKGAGSGE
K508 ADFKVYTKGAGSGEL
K508 ADFKVYTKGAGSGEL
S512 VYTKGAGSGELKVTV
Y538 KDLGDGVYGFEYYPT
K578 GTECGNQKVRAWGPG
Y643 WPQEAGEYAVHVLCN
K691 KTGVAINKPAEFTVD
K700 AEFTVDAKHAGKAPL
T730 VKDNGNGTYSCSYVP
Y731 KDNGNGTYSCSYVPR
S732 DNGNGTYSCSYVPRK
S734 GNGTYSCSYVPRKPV
Y735 NGTYSCSYVPRKPVK
S753 MVSWGGVSIPNSPFR
S757 GGVSIPNSPFRVNVG
S767 RVNVGAGSHPNKVKV
K771 GAGSHPNKVKVYGPG
K773 GSHPNKVKVYGPGVA
Y775 HPNKVKVYGPGVAKT
K781 VYGPGVAKTGLKAHE
K781 VYGPGVAKTGLKAHE
T782 YGPGVAKTGLKAHEP
T790 GLKAHEPTYFTVDCT
Y791 LKAHEPTYFTVDCTE
T793 AHEPTYFTVDCTEAG
K837 DNDTFTVKYTPCGAG
K837 DNDTFTVKYTPCGAG
S860 ADQATPTSPIRVKVE
K865 PTSPIRVKVEPSHDA
K874 EPSHDASKVKAEGPG
K891 RTGVELGKPTHFTVN
K900 THFTVNAKTAGKGKL
K906 AKTAGKGKLDVQFSG
S912 GKLDVQFSGLAKGDA
A915 DVQFSGLAKGDAVRD
K916 VQFSGLAKGDAVRDV
S959 GGDHIPKSPFSVGVS
S966 SPFSVGVSPSLDLSK
S968 FSVGVSPSLDLSKIK
S972 VSPSLDLSKIKVSGL
K973 SPSLDLSKIKVSGLV
K994 KDQEFTVKSKGAGGQ
K1003 KGAGGQGKVASKIVS
S1010 KVASKIVSPSGAAVP
K1019 SGAAVPCKVEPGLGA
Y1047 PYEVEVTYDGVPVPG
D1048 YEVEVTYDGVPVPGS
S1055 DGVPVPGSPFPVEAV
K1071 PTKPSKVKAFGPGLQ
K1071 PTKPSKVKAFGPGLQ
N1081 GPGLQGGNAGSPARF
S1084 LQGGNAGSPARFTID
S1161 VVPCFDASKVKCSGP
K1162 VPCFDASKVKCSGPG
K1164 CFDASKVKCSGPGLE
Y1261 DTSGVQCYGPGIEGQ
T1286 SVDARALTQTGGPHV
K1294 QTGGPHVKARVANPS
T1307 PSGNLTDTYVQDCGD
Y1308 SGNLTDTYVQDCGDG
T1334 GVHSVDVTYDGSPVP
D1336 HSVDVTYDGSPVPSS
S1338 VDVTYDGSPVPSSPF
S1343 DGSPVPSSPFQVPVT
T1377 TNKPNKFTVETRGAG
S1436 GGHQVPGSPFKVPVH
T1446 KVPVHDVTDASKVKC
S1449 VHDVTDASKVKCSGP
S1454 DASKVKCSGPGLSPG
S1459 KCSGPGLSPGMVRAN
S1470 VRANLPQSFQVDTSK
T1475 PQSFQVDTSKAGVAP
S1476 QSFQVDTSKAGVAPL
K1477 SFQVDTSKAGVAPLQ
K1491 QVKVQGPKGLVEPVD
D1504 VDVVDNADGTQTVNY
S1514 QTVNYVPSREGsYSI
S1518-p YVPSREGsYSISVLY
S1533 GEEEVPRSPFKVKVL
K1538 PRSPFKVKVLPTHDA
K1538 PRSPFKVKVLPTHDA
T1542 FKVKVLPTHDASKVK
S1546 VLPTHDASKVKASGP
K1590 QITDPEGKPKKTHIQ
T1594 PEGKPKKTHIQDNHD
T1603 IQDNHDGTYTVAYVP
Y1604 QDNHDGTYTVAYVPD
T1605 DNHDGTYTVAYVPDV
K1621 GRYTILIKYGGDEIP
S1630 GGDEIPFSPYRVRAV
Y1632 DEIPFSPYRVRAVPT
Y1712 TAPQPGKYVICVRFG
S1726 GGEHVPNSPFQVTAL
T1731 PNSPFQVTALAGDQP
T1742 GDQPTVQTPLRPQQL
Y1753 PQQLPSQYTYPQGSQ
T1754 QQLPSQYTYPQGSQQ
Y1755 QLPSQYTYPQGSQQT
K1793 VIPFTIKKGEITGEV
K1816 QPSITDNKDGTVTVR
Y1854 PLQFYVDYVNCGHIT
Y1863 NCGHITAYGPGLTHG
Y1924 LPVLPGDYSILVKYN
Y1930 DYSILVKYNDQHIPG
S1938 NDQHIPGSPFTARVT
S1949 ARVTGDDSMRMSHLK
S1953 GDDSMRMSHLKVGSA
K1956 SMRMSHLKVGSAADI
S1968 ADIPINISETDLSLL
K1992 REEPCLLKRLRNGHV
S2045 DASRVRVSGQGLHEG
T2054 QGLHEGHTFEPAEFI
S2080 SLSIEGPSKVDINTE
S2120 ADQHVPGSPFSVKVT
T2127 SPFSVKVTGEGRVKE
S2135 GEGRVKESITRRRRA
S2144-p TRRRRAPsVANVGsH
S2150-p PsVANVGsHCDLSLK
S2155 VGsHCDLSLKIPEIS
S2162 SLKIPEISIQDMTAQ
S2172 DMTAQVTSPSGKTHE
T2189 IVEGENHTYCIRFVP
Y2190 VEGENHTYCIRFVPA
K2209 HTVSVKYKGQHVPGS
S2216 KGQHVPGSPFQFTVG
S2276 GPSKAEISFEDRKDG
S2284 FEDRKDGSCGVAYVV
Y2297 VVQEPGDYEVSVKFN
S2311 NEEHIPDSPFVVPVA
S2319 PFVVPVASPSGDARR
S2321 VVPVASPSGDARRLt
T2328-p SGDARRLtVSSLQES
S2330 DARRLtVSSLQESGL
K2353 AVSLNGAKGAIDAKV
S2362 AIDAKVHSPSGALEE
S2364 DAKVHSPSGALEECY
Y2371 SGALEECYVTEIDQD
T2373 ALEECYVTEIDQDKY
Y2380 TEIDQDKYAVRFIPR
Y2392 IPRENGVYLIDVKFN
S2406 NGTHIPGSPFKIRVG
K2409 HIPGSPFKIRVGEPG
K2409 HIPGSPFKIRVGEPG
K2465 IDGPSKVKMDCQECP
Y2475 CQECPEGYRVTYTPM
Y2497 SIKYGGPYHIGGSPF
S2502 GPYHIGGSPFKAKVT
S2515-p VTGPRLVsNHSLHET
S2518 PRLVsNHSLHETSSV
T2591 VGVHGPRTPCEEILV
K2599 PCEEILVKHMGSRLY
Y2606 KHMGSRLYsVSYLLK
S2607-p HMGSRLYsVSYLLKD
S2609 GSRLYsVSYLLKDKG
Y2610 SRLYsVSYLLKDKGE
K2613 YsVSYLLKDKGEYTL
K2615 VSYLLKDKGEYTLVV
Y2634 EHIPGSPYRIMVP__
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