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FUT6 (human)

Overview FUT6 Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates. Belongs to the glycosyltransferase 10 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase; EC 2.4.1.65 Cellular Component: Golgi apparatus; integral to membrane Molecular Function: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; alpha(1,3)-fucosyltransferase activity; fucosyltransferase activity Biological Process: protein amino acid glycosylation; L-fucose catabolic process Reference #:  P51993 (UniProtKB) Alt. Names/Synonyms: Alpha-(1,3)-fucosyltransferase; FCT3A; FLJ40754; FT1A; Fuc-TVI; Fucosyltransferase 6; fucosyltransferase 6 (alpha (1,3) fucosyltransferase); Fucosyltransferase VI; FucT-VI; FUT6; Galactoside 3-L-fucosyltransferase Gene Symbols: FUT6 Molecular weight: 41,860 Da Basal Isoelectric point: 8.92  Predict pI for various phosphorylation states

Select Structure to View Below FUT6

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	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		S123-p	PSAQLPRsPRRQGQR
0	1		Y208-p	PNSARVRyyQSLQAH
0	1		Y209-p	NSARVRyyQSLQAHL
0	1		Y221-p	AHLKVDVyGRSHKPL

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