Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Belongs to the dynein light chain family. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Microtubule-binding; Motor
Molecular Function: protein binding; cytoskeletal protein binding; motor activity
Biological Process: macroautophagy; transport; apoptosis; organelle organization and biogenesis; programmed cell death; antigen processing and presentation of exogenous peptide antigen via MHC class II; synaptic target recognition; microtubule-based process
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.