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Protein Page:
CCNA1 (human)

Overview
CCNA1 May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. Belongs to the cyclin family. Cyclin AB subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cancer Testis Antigen (CTA)
Cellular Component: microtubule cytoskeleton; nucleoplasm; cytosol
Molecular Function: protein binding; protein kinase binding
Biological Process: G1/S-specific transcription in mitotic cell cycle; mitosis; male meiosis I; regulation of G2/M transition of mitotic cell cycle; spermatogenesis; mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; G2/M transition of mitotic cell cycle; G1/S transition of mitotic cell cycle
Reference #:  P78396 (UniProtKB)
Alt. Names/Synonyms: CCNA1; CT146; cyclin A1; Cyclin-A1
Gene Symbols: CCNA1
Molecular weight: 52,358 Da
Basal Isoelectric point: 4.99  Predict pI for various phosphorylation states
CST Pathways:  AMPK Signaling
Select Structure to View Below

CCNA1

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T168-p VYEVDTGtLKSDLHF
0 1 S280-p DRFLSCMsVLRGKLQ
0 1 T291 GKLQLVGTAAMLLAS
0 1 S298 TAAMLLASKYEEIYP
  mouse

 
M124 VYEVDTSMLKSDLHF
S236 DRFLSCMSVLRGKLQ
T247-p GKLQLVGtAAILLAs
S254-p tAAILLAsKYEEIYP
  rat

 
M124 VYEVDTSMLKSDLHF
S236 DRFLSCMSVLRGKLQ
T247 GKLQLVGTAAILLAS
S254 TAAILLASKYEEIYP
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