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CCNA1 (human)

Overview CCNA1 May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. Belongs to the cyclin family. Cyclin AB subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: Cancer Testis Antigen (CTA) Cellular Component: nucleoplasm; microtubule cytoskeleton; cytosol Molecular Function: protein binding; protein kinase binding Biological Process: G1/S-specific transcription in mitotic cell cycle; mitosis; male meiosis I; cell division; spermatogenesis; mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; G2/M transition of mitotic cell cycle; G1/S transition of mitotic cell cycle Reference #:  P78396 (UniProtKB) Alt. Names/Synonyms: CCNA1; CT146; cyclin A1; Cyclin-A1 Gene Symbols: CCNA1 Molecular weight: 52,358 Da Basal Isoelectric point: 4.99  Predict pI for various phosphorylation states CST Pathways:  AMPK Signaling

Select Structure to View Below CCNA1

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	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		S280-p	DRFLSCMsVLRGKLQ
0	1		T291	GKLQLVGTAAMLLAS
0	1		S298	TAAMLLASKYEEIYP

	mouse
S236	DRFLSCMSVLRGKLQ
T247-p	GKLQLVGtAAILLAs
S254-p	tAAILLAsKYEEIYP

	rat
S236	DRFLSCMSVLRGKLQ
T247	GKLQLVGTAAILLAS
S254	TAAILLASKYEEIYP

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