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TOMM40 (human)

Overview TOMM40 Channel-forming protein essential for import of protein precursors into mitochondria. Belongs to the Tom40 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: Mitochondrial Cellular Component: pore complex; mitochondrial outer membrane translocase complex; mitochondrion; integral to membrane; integral to mitochondrial outer membrane Molecular Function: voltage-gated anion channel activity; protein transmembrane transporter activity; porin activity Biological Process: cellular protein metabolic process; protein targeting to mitochondrion Reference #:  O96008 (UniProtKB) Alt. Names/Synonyms: C19orf1; D19S1177E; Mitochondrial import receptor subunit TOM40 homolog; mitochondrial outer membrane protein; p38.5; PER-EC1; PEREC1; Protein Haymaker; TOM40; TOMM40; Translocase of outer membrane 40 kDa subunit homolog; translocase of outer mitochondrial membrane 40 homolog (yeast) Gene Symbols: TOMM40 Molecular weight: 37,893 Da Basal Isoelectric point: 6.79  Predict pI for various phosphorylation states

Select Structure to View Below TOMM40

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	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		K102	PIQMEGVKLTVNKGL
0	1		K107	GVKLTVNKGLSNHFQ
0	4		K175-u	LGPGLRSkMAIQTQQ
0	4		K184-u	AIQTQQSkFVNWQVD
0	1		Y194-p	NWQVDGEyRGSDFTA
0	6		K309-u	GYQLDLPkANLLFKG
0	1		T338-p	KLPPLPLtLALGAFL

	mouse
K102-u	PVQMEGVkLTVNkGL
K107-u	GVkLTVNkGLSNRFQ
K175-u	LSPGLRSkMAIQTQQ
K184	AIQTQQSKFVNWQVD
Y194	NWQVDGEYRGSDFTA
K309	GYQLDLPKANFLFKG
T338	KLPPLPLTLSLCAFL

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