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Protein Page:
TOMM40 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
TOMM40 Channel-forming protein essential for import of protein precursors into mitochondria. Belongs to the Tom40 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Mitochondrial; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: pore complex; mitochondrion; mitochondrial outer membrane translocase complex; integral to membrane; integral to mitochondrial outer membrane
Molecular Function: protein transmembrane transporter activity; porin activity
Biological Process: cellular protein metabolic process; ion transport; protein targeting to mitochondrion
Reference #:  O96008 (UniProtKB)
Alt. Names/Synonyms: C19orf1; D19S1177E; Mitochondrial import receptor subunit TOM40 homolog; mitochondrial outer membrane protein; p38.5; PER-EC1; PEREC1; Protein Haymaker; TOM40; TOMM40; Translocase of outer membrane 40 kDa subunit homolog; translocase of outer mitochondrial membrane 40 homolog (yeast)
Gene Symbols: TOMM40
Molecular weight: 37,893 Da
Basal Isoelectric point: 6.79  Predict pI for various phosphorylation states
Select Structure to View Below

TOMM40

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K102 PIQMEGVKLTVNKGL
0 1 K107 GVKLTVNKGLSNHFQ
0 4 K175-ub LGPGLRSkMAIQTQQ
0 4 K184-ub AIQTQQSkFVNWQVD
0 1 Y194-p NWQVDGEyRGSDFTA
0 1 Y254-p VMSLAGKytLNNWLA
0 1 T255-p MSLAGKytLNNWLAT
0 1 T273-p GQAGMHAtYYHKASD
0 6 K309-ub GYQLDLPkANLLFKG
0 1 S317-p ANLLFKGsVDsNWIV
0 1 S320-p LFKGsVDsNWIVGAT
0 1 T338-p KLPPLPLtLALGAFL
  mouse

 
K102-ub PVQMEGVkLTVNkGL
K107-ub GVkLTVNkGLSNRFQ
K175-ub LSPGLRSkMAIQTQQ
K184 AIQTQQSKFVNWQVD
Y194 NWQVDGEYRGSDFTA
Y254 VMSLAGKYTLNNWLA
T255 MSLAGKYTLNNWLAT
T273 GQAGMHATYYHKASD
K309 GYQLDLPKANFLFKG
S317 ANFLFKGSVNSNWIV
S320 LFKGSVNSNWIVGAT
T338 KLPPLPLTLSLCAFL
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