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Protein Page:
TFIIIB50 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
TFIIIB50 General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Belongs to the TFIIB family. Note: This description may include information from UniProtKB.
Protein type: Transcription regulation
Cellular Component: nucleoplasm
Molecular Function: zinc ion binding
Biological Process: transcription from RNA polymerase III promoter; regulation of transcription, DNA-dependent; transcription initiation; gene expression
Reference #:  Q9HAW0 (UniProtKB)
Alt. Names/Synonyms: B-related factor 2; BRF-2; BRF2; BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; BRFU; FLJ11052; hBRFU; hTFIIIB50; RNA polymerase III transcription initiation factor BRFU; TFIIIB50; transcription factor IIB- related factor, TFIIIB50; Transcription factor IIIB 50 kDa subunit
Gene Symbols: BRF2
Molecular weight: 46,533 Da
Basal Isoelectric point: 8.28  Predict pI for various phosphorylation states
Select Structure to View Below

TFIIIB50

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T140-p LTMGAICtLLYADLD
0 1 S150-p YADLDVFsSTYMQIV
0 1 K192-ub ASPSVPAkyVEDKEK
0 1 Y193-p SPSVPAkyVEDKEKM
0 1 S202-p EDKEKMLsRTMQLVE
0 1 T218-p ANETWLVtGRHPLPV
0 2 Y260-p LANVDLPyPASSRLQ
0 1 S306-p DLLQHRQsLVRSAFR
0 1 K324-ub AEVETREkEPPGWGQ
0 13 S353-p PQGKRPAsPALLLPP
0 10 S365-p LPPCMLKsPKRICPV
0 3 S385-p VTGDENIsDSEIEQY
  mouse

 
T140 LTMGTICTLLYADLD
S150 YADLDLFSGTYMQMV
K192 ASPSVPAKYVEDKDK
Y193 SPSVPAKYVEDKDKM
S202 EDKDKMLSRTLLLVE
T218 ADETWLVTGRHPLPI
Y260 LANVDLPYPAASRLQ
M306 DLLQHRHMLVRTAFR
- gap
S354 PKRKRRASPTPLLPP
P366 LPPCMLKPPKRTHTL
S386-p VTGDEDIsDSEIEQY
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