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Protein Page:
PPP2R2C (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
PPP2R2C The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B family. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Protein phosphatase, regulatory subunit
Cellular Component: protein phosphatase type 2A complex
Molecular Function: protein binding; protein phosphatase type 2A regulator activity
Biological Process: regulation of catalytic activity; signal transduction
Reference #:  Q9Y2T4 (UniProtKB)
Alt. Names/Synonyms: 2ABG; B55-GAMMA; gamma isoform of regulatory subunit B55, protein phosphatase 2; IMYPNO; IMYPNO1; MGC33570; phosphoprotein phosphatase 2A BR gamma regulatory chain; PP2A subunit B isoform B55-gamma; PP2A subunit B isoform gamma; PP2A subunit B isoform PR55-gamma; PP2A subunit B isoform R2-gamma; PP2A, subunit B, B-gamma isoform; PP2A, subunit B, B55-gamma isoform; PP2A, subunit B, PR55-gamma isoform; PP2A, subunit B, R2-gamma isoform; PPP2R2C; PR52; PR55G; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform; protein phosphatase 2, regulatory subunit B, gamma; protein phosphatase 2A1 B gamma subunit; serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, gamma isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
Gene Symbols: PPP2R2C
Molecular weight: 51,515 Da
Basal Isoelectric point: 5.92  Predict pI for various phosphorylation states
Select Structure to View Below

PPP2R2C

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 4 K125-ub WKITERDkRPEGYNL
0 1 K133 RPEGYNLKDEEGKLK
0 1 K138 NLKDEEGKLKDLSTV
0 2 K263-ub ALCDKHSkLFEEPED
0 1 T318-p MEARPIEtYQVHDYL
0 1 S405-p KRRRDDIsVDsLDFT
0 1 S408-p RDDIsVDsLDFTKKI
  mouse

 
K125-ub WKITERDkRPEGYNL
K133-ac RPEGYNLkDEEGkLK
K138-ac NLkDEEGkLKDLSTV
K263-ub ALCDKHSkLFEEPED
T318 MEARPIETYQVHDYL
S405 KRRRDDISVDSLDFT
S408 RDDISVDSLDFTKKI
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